125
Views
13
CrossRef citations to date
0
Altmetric
Original Articles

The Use of Cultured Primary Bovine Colon Epithelial Cells as a Screening Model to Detect Genotoxic Effects of Heterocyclic Aromatic Amines in the Comet Assay

&
Pages 947-953 | Published online: 04 Jun 2008

REFERENCES

  • Babich , H. and Borenfreund , E. 1992 . “ Neutral red assay for toxicology in vitro ” . In In vitro methods of toxicology , Edited by: Watson , R. R. Boca Raton, FL : CRC Press . Chapter 17.
  • Birkner , S. , Weber , S. , Dohle , A. , Achmahl , G. , Bolt , H. M. and Föllmann , W. 2004 . Growth and characterization of primary bovine colon epithelial cells in vitro . ATLA , 32 : 555 – 571 .
  • Birkner , S. , Weber , S. , Dohle , A. , Achmahl , G. , Bolt , H. M. and Föllmann , W. 2003 . Activities of drug metabolizing enzymes in bovine colon epithelial cell cultures . Arch. Toxicol. , 77 : 621 – 629 .
  • Booth , C. , Patel , S. , Bennion , G. R. and Potten , C. S. 1995 . The isolation and culture of adult mouse colonic epithelium . Epithelial Cell Biol. , 4 : 76 – 86 .
  • Carman , R. J. , Van Tassel , R. L. , Kingston , D. G. , Bashir , M. and Wilkins , T. D. 1987 . Conversion of IQ, a dietary pyrolysis carcinogen to a direct-acting mutagen by normal intestinal bacteria of humans . Mutat. Res. , 206 : 335 – 342 .
  • Crofts , F. G. , Strickland , P. T. , Hayes , C. L. and Sutter , T. R. 1997 . Metabolism of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhiP) by human cytochrome P450 1B1 . Carcinogenesis , 18 : 1793 – 1798 .
  • Deveney , C. W. , Rand-Luby , L. , Rutten , M. J. , Luttropp , C. A. , Fowler , W. M. , Land , J. , Meichsner , C. L. , Farahmand , M. , Sheppard , B. C. , Crass , R. A. and Deveney , M. D. 1996 . Establishment of human colonic epithelial cells in long-term culture . J. Surg. Res. , 64 : 161 – 169 .
  • Eisenbrand , G. and Tang , W. 1993 . Food-borne heterocyclic amines. Chemistry, formation, occurrence and biological activities. A literature review . Toxicology , 84 : 1 – 82 .
  • Föllmann , W. , Weber , S. and Birkner , S. 2000 . Primary cell cultures of bovine colon epithelium: Isolation and cell culture of colonocytes . Toxicol. In Vitro , 14 : 435 – 445 .
  • Fonti , R. , Latella , G. , Bises , G. , Magliocca , F. , Nobili , F. , Caprilli , R. and Sambuy , Y. 1994 . Human colonocytes in primary culture: a model to study epithelial growth, metabolism and differentiation . Int. J. Colorect. Dis. , 9 : 13 – 22 .
  • Garner , R. C. , Lightfoot , T. J. , Cupid , B. C. , Russel , D. , Coxhead , J M. , Kutschera , W. , Priller , A. , Rom , W. , Steier , P. , Alexander , D. J. , Leveson , S. H. , Dingley , K. H. , Mauthe , R. J. and Turteltaub , K. W. 1999 . Comparative biotransformation studies of MelQx and PhiP in animal models and humans . Cancer Lett. , 143 : 161 – 165 .
  • Hayatsu , H. , ed. 1990 . Mutagens in food: Detection and prevention , Boca Raton, FL : CRC Press .
  • Hidalgo , I. J. 1996 . Cultured intestinal epithelial cell models . Pharm. Biotechnol. , 8 : 35 – 50 .
  • Marquardt , H. and Schäfer , S. G. , eds. 1994 . Lehrbuch der Toxikologie , Leipzig : Wissenschaftsverlag Mannheim .
  • Peters , W. H. , Boon , C. E. , Roelofs , H. M. , Wobbes , T. , Nagengast , F. M. and Kremers , P. G. 1992 . Expression of drug-metabolizing enzymes and P-170 glycoprotein in colorectal carcinoma and normal mucosa . Gastroenterology , 103 : 448 – 455 .
  • Petry , T. W. , Josephy , P. D. , Pagano , D. A. , Zeiger , E. , Knecht , K. T. and Eling , T. E. 1989 . Prostaglandin hydroperoxidase-dependent activation of heterocyclic aromatic amines . Carcinogenesis , 10 : 2201 – 2207 .
  • Pool-Zobel , B. L. and Leucht , U. 1997 . Induction of DNA damage by risk factors of colon cancer in human colon cells derived from biopsies . Mutat. Res. , 375 : 105 – 115 .
  • Reddy , P. M. , Sahi , J. , Desai , G. , Vidyasagar , D. and Rao , M. C. 1996 . Altered growth and attachment of rabbit crypt colonocytes isolated from different developmental stages . Pediatr. Res. , 39 : 287 – 294 .
  • Rumney , C. J. , Rowland , I. R. and O'Neill , I. K. 1993 . Conversion of IQ to 7-OHIQ by gut microflora . Nutr. Cancer , 19 : 67 – 76 .
  • Schut , H. A. J. and Snyderwine , E. G. 1999 . DNA adducts of heterocyclic amine food mutagens: Implication for mutagenesis and carcinogenesis . Carcinogenesis , 20 : 353 – 368 .
  • Singh , N. P. , McCoy , M. T. , Tice , R. R. and Schneider , E. L. 1988 . A simple technique for quantification of low levels of DNA damage in cells . Exp. Cell Res. , 175 : 184 – 191 .
  • Thompson , A. A. , Dilworth , S. and Hay , R. J. 1985 . Isolation and culture of colonic epithelial cells in serum-free medium . J. Tissue Culture Methods , 9 : 117 – 122 .
  • Tice , R. R. , Agurell , E. , Anderson , D. , Burlinson , B. , Hartmann , A. , Kobayashi , H. , Miyamae , Y. , Rojas , E. , Ryu , J. C. and Sasaki , Y. S. 2000 . Single cell gel/comet assay: Guidelines for in vitro and in vivo genetic toxicology testing . Environ. Mol. Mutagen. , 35 : 206 – 221 .
  • Turesky , R. J. , Constable , A. , Laurent , B. F. and Guengerich , F. P. 1999 . Interspecies differences in metabolism of heterocyclic aromatic amines by rat and human P450 1A2 . Cancer Lett. , 143 : 109 – 112 .
  • Turesky , R. J. , Lang , N. P. , Butler , M. A. , Teitel , C. H. and Kadlubar , F. F. 1991 . Metabolic activation of carcinogenic heterocyclic aromatic amines by human liver and colon . Carcinogenesis , 12 : 1839 – 1845 .
  • Turteltaub , K. W. , Dingley , K. H. , Curtis , K. D. , Malfatti , M. A. , Turesky , R. J. , Garner , R. C. , Felton , J. S. and Lang , N. P. 1999 . Macromolecular adduct formation and metabolism of heterocyclic amines in humans and rodents at low doses . Cancer Lett. , 143 : 149 – 155 .
  • Van Tassel , R. L. , Kingston , D. G. I. and Wilkins , T. D. 1990 . Metabolism of dietary genotoxins by the human colonic microflora; The fecapentaenes and heterocyclic amines . Mutat. Res. , 238 : 209 – 221 .
  • Wakabayashi , K. , Nagao , M. , Esumi , H. and Sugimura , T. 1992 . Food-derived mutagens and carcinogens . Cancer Res. , 52 : 2092 – 2098 .
  • Weisburger , J. H. , Rivenson , A. , Reinhardt , J. , Aliaga , C. , Braley , J. , Dolan , L. M. , Williams , G. M. , Zang , E. , Kingston , D. G. and Bashir , M. 1994 . Genotoxicity and carcinogenicity in rats and mice of 2-amino-3,6-dihydro-3-methyl-7H-imidazolo[4,5-f]quinolin-7-one: An intestinal bacterial metabolite of 2-amino-3-methyl-3H-imidazo[4,5-f]quinoline . J. Natl. Cancer Inst. , 86 : 25 – 30 .
  • Whitehead , R. H. , Brown , A. and Bhatha , l P. S. 1987 . A method for the isolation and culture of human colonic crypts in collagen gels . In Vitro Cell Dev. Biol. , 23 : 436 – 442 .
  • Yeh , K. Y. and Chorpra , D. P. 1980 . Epithelial cell cultures from the colon of the suckling rat . In Vitro , 16 : 976 – 986 .

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.