Integrated Disinfection By-Products (DBP) Mixtures Research: Gene Expression Alterations in Primary Rat Hepatocyte Cultures Exposed to DBP Mixtures Formed by Chlorination and Ozonation/Postchlorination

REFERENCES

• Ammerschlaeger , M. , Beigel , J. , Klein , K. and Mueller , S. O. 2004 . Characterization of the species-specificity of peroxisome proliferators in rat and human hepatocytes . Toxicol. Sci. , 78 : 229 – 240 .
   PubMed Web of Science ®Google Scholar
• Baker , V. A. , Harries , H. M. , Waring , J. F. , Duggan , C. M. , Ni , H. A. , Jolly , R. A. , Yoon , L. W. , De Souza , A. T. , Schmid , J. E. , Brown , H. R. , Ulrich , R. G. and Rockett , J. C. 2004 . Clofibrate-induced gene expression changes in rat liver: A cross-laboratory analysis using membrane cDNA arrays . Environ. Health. Perspect. , 112 : 428 – 438 .
   PubMed Web of Science ®Google Scholar
• Bull , R. J. , Sanchez , I. M. , Nelson , M. A. , Larson , J. L. and Lansing , A. J. 1990 . Liver tumor induction in B6C3F1 mice by dichloroacetate and trichloroacetate . Toxicology , 63 : 341 – 359 .
   PubMed Web of Science ®Google Scholar
• Cantor , K. P. 1977 . Drinking water and cancer . Cancer Causes Control , 8 : 292 – 308 .
   Web of Science ®Google Scholar
• Cornwell , P. D. , De Souza , A. T. and Ulrich , R. G. 2004 . Profiling of hepatic gene expression in rats treated with fibric acid analogs . Mutat. Res. , 549 : 131 – 145 .
   PubMed Web of Science ®Google Scholar
• Crosby , L. M. , Hyder , K. S. , DeAngelo , A. B. , Kepler , T. A. , Gaskill , B. , Benavides , B. R. , Yoon , L. and Morgan , K. T. 2000 . Morphologic analysis correlates with gene expression changes in cultured F344 rat mesothelial cells . Toxicol. Appl. Pharmacol. , 169 : 205 – 221 .
   PubMed Web of Science ®Google Scholar
• Crunkhorn , S. E. , Plant , K. E. , Gibson , G. G. , Kramer , K. , Lyon , J. , Lord , P. G. and Plant , N. J. 2003 . Gene expression changes in rat liver following exposure to liver growth agents: Role of Kupffer cells in xenobiotic-mediated liver growth . Biochem. Pharmacol. , 67 : 107 – 118 .
   Web of Science ®Google Scholar
• Daniel , F. B. , DeAngelo , A. B. , Stober , J. A. , Olson , G. and Page , N. P. 1992 . Hepatocarcinogenicity of chloral hydrate, 2-chloroacetaldehyde, and dichloroacetic acid in the male B6C3F1 mouse . Fundam. Appl. Toxicol. , 19 : 159 – 168 .
   PubMedGoogle Scholar
• DeAngelo , A. B. , Daniel , F. B. , Stober , J. A. and Olson , G. R. 1991 . The carcinogenicity of dichloroacetic acid in the male B6C3F1 mouse . Fundam. Appl. Toxicol. , 16 : 337 – 347 .
   PubMedGoogle Scholar
• DeAngelo , A. B. , Daniel , F. B. , McMillan , L. , Wersing , P. and Savage , R. E. 1989 . Species and strain sensitivity to the induction of peroxisome proliferation by chloroacetic acid . Toxicol. Appl. Pharmacol. , 101 : 285 – 298 .
   PubMed Web of Science ®Google Scholar
• DeAngelo , A. B. , Daniel , F. B. , Most , B. M. and Olson , G. R. 1996 . The carcinogenicity of dichloroacetic acid in the male Fischer 344 rat . Toxicology , 114 : 207 – 221 .
   PubMed Web of Science ®Google Scholar
• DeAngelo , A. B. , George , J. H. and House , D. E. 1999 . Hepatocarcinogenicity in the male B6C3F1 mouse following a life-time exposure to dichloroacetic acid in the drinking water: Dose response and mode of action . J. Toxicol. Environ. Health A , 58 : 485 – 507 .
   PubMed Web of Science ®Google Scholar
• DeAngelo , A. B. , George , J. H. , Kilburn , S. R. , Moore , T. M. and Wolf , D. C. 1998 . Carcinogenicity of potassium bromate administered in the drinking water to male B6C3F1 mice and F344 rats . Toxicol. Pathol. , 26 : 587 – 594 .
   PubMed Web of Science ®Google Scholar
• DeAngelo , A. B. , Geter , D. R. , Rosenberg , D. W. and George , M. H. 2002 . The induction of aberrant crypt foci (ACF) in the colons of rats by brominated trihalomethanes administered in the drinking water . Cancer Lett. , 187 : 25 – 31 .
   PubMed Web of Science ®Google Scholar
• Decker , T. and Lohmann-Matthes , M.-L. 1998 . A quick and simple method for the quantitation of lactate dehydrogenase release in measurements of cellular cytotoxicity and tumor necrosis factor (TNF) activity . J. Immunol. Methods , 15 : 61 – 69 .
   Google Scholar
• Everhart , J. L. , Kurtz , D. T. and McMillan , J. M. 1998 . Dichloroacetic acid induction of peroxisome proliferation in cultured hepatocytes . J. Biochem. Mol. Toxicol. , 12 : 351 – 359 .
   PubMed Web of Science ®Google Scholar
• George , M. H. , Kilburn , S. R. , Moore , T. M. and DeAngelo , A. B. 2000 . The carcinogenicity of chloral hydrate administered in the drinking water to male B6C3F1 mice and F344 rats . Toxicol. Pathol. , 28 : 610 – 618 .
   PubMed Web of Science ®Google Scholar
• George , M. H , Kilburn , S. , Moore , T. M. and DeAngelo , A. B. 2002 . Evaluation of the carcinogenicity of bromodichloromethane administered in the drinking water to male B6C3F1 mice and F344 rats . Int. J. Toxicol. , 21 : 1 – 12 .
   Web of Science ®Google Scholar
• Geter , D. R. , George , M. H. , Moore , T. M. , Kilburn , S. , Huggins-Clark , G. and DeAngelo , A. B. 2003 . Vehicle and route of administration effects on the induction of ACF in the colons of male F344/N rats exposed to bromo-dichloromethane . J. Toxicol. Environ. Health A , 67 : 23 – 29 .
   Web of Science ®Google Scholar
• Geter , D. R. , George , M. H. , Moore , T. M. , Kilburn , S. , Huggins-Clark , G. and DeAngelo , A. B. 2004 . The effects of a high animal fat diet on the induction of aberrant crypt foci in the colons of male F344/N rats exposed to trihalomethanes in the drinking water . Toxicol. Lett. , 147 : 245 – 252 .
   PubMed Web of Science ®Google Scholar
• Geter , D. R. , Moore , T. M. , George , M. H. , Kilburn , S. R. , Swank , A. E. , Huggins-Clark , G. , Allen , J. W. , Nelson , G. M. , Winkfield , E. and DeAngelo , A. B. 2005 . Tribromo-methane exposure and dietary folate deficiency in the formation of aberrant crypt foci in the colons of F344/N rats . Food Chem. Toxicol. , 43 : 1405 – 1412 .
   PubMed Web of Science ®Google Scholar
• Kepler , T. B. , Crosby , L. and Morgan , K. T. 2002 . Normalization and analysis of DNA microarray data by self-consistency and local regression . Genome Biol. , 28 : 3
   Google Scholar
• Klaunig , J. E. , Babich , M. A. , Baetcke , K. P. , Cook , J. C. , Corton , J. C. , David , R. M.. , DeLuca , J. G. , Lai , D.Y. , McKee , R. H. , Peters , J. M. , Roberts , R. A. and Fenner-Crisp , P. A. 2003 . PPARalpha antagonist-induced rodent tumors: Modes of action and human relevance . Crit. Rev. Toxicol. , 33 : 655 – 780 .
   PubMed Web of Science ®Google Scholar
• Krasner , S. W. , Weinberg , H. S. , Richardson , S. D. , Pastor , S. J. , Sclimenti , M. J. , Onstad , G. D. and Thruston , A. D. Jr. 2006 . Occurrence of a new generation of disinfection byproducts . Environ. Sci. Technol. , 40 : 7175 – 7185 .
   PubMed Web of Science ®Google Scholar
• Kumar , V. , Abbas , A. K. , Mitchell , R. and Fausto , N. 2007 . Robbins basic pathology , 8th , Philadelphia : W. B. Saunders .
   Google Scholar
• Legrand , C. , Bour , J. M and Jacob , C. 1992 . Lactate dehydrogenase (LDH) activity of the number of dead cells in the medium of cultured eukaryotic cells as marker . J. Biotechnol. , 25 : 231 – 243 .
   PubMed Web of Science ®Google Scholar
• Miltner , R. J. , Speth , T. F. , Richardson , S. D. , Krasner , S. W. , Weinberg , H. S. and Simmons , J. E. 2008 . Integrated disinfection byproducts mixtures research: Disinfection of drinking waters by chlorination and ozonation/postchlorination treatment scenarios . J. Toxicol. Environ. Health A , this issue.
   Web of Science ®Google Scholar
• Morgan , K. T. , Ni , H. , Brown , H. R. , Yoon , L. , Qualls , C. W. , Crosby , L. M. , Reynolds , R. , Gaskill , B. , Anderson , S. P. , Kepler , T. B. , Brainard , T. , Liv , N. , Easton , M. , Merrill , C. , Creech , D. , Sprenger , D. , Conner , G. , Johnson , P. R. , Fox , T. , Sartor , M. , Richard , E. , Kuruvilla , S. , Casey , W. and Benavides , G. 2002 . Application of cDNA microarray technology to in vitro toxicology and the selection of genes for a real-time RT-PCR-based screen for oxidative stress in Hep-G2 cells . Toxicol. Pathol. , 30 : 435 – 451 .
   PubMed Web of Science ®Google Scholar
• Morris , R. , Audet , A.-M. , Angelillo , I. , Chalmers , T. and Mosteller , F. 1992 . Chlorination, chlorination by-products and cancer: A meta-analysis . Am. J. Public Health , 82 : 955 – 963 .
   PubMed Web of Science ®Google Scholar
• Richardson , S. D. , Thruston , A. D. , Krasner , S. W. , Weinberg , H. S. , Miltner , R. J. , Speth , T. F. , Schenck , K. M. , Narotsky , M. G. , McKague , B. and Simmons , J. E . 2008 . Integrated disinfection byproducts mixtures research: Comprehensive characterization of water concentrates prepared from chlorinated and ozonated/postchlorinated drinking water . J. Toxicol. Environ. Health A , this issue.
   Web of Science ®Google Scholar
• Simmons , J. E. , Teuschler , L. K. , Gennings , C. , Speth , T. F. , Richardson , S. D. , Miltner , R. J. , Narotsky , M. G. , Schenck , K. M. , Hunter , E. S. III and Rice , G. 2004 . Component-based and whole-mixture techniques for addressing the toxicity of drinking-water disinfection by-product mixtures . J. Toxicol. Environ. Health A , 67 : 741 – 754 .
   PubMed Web of Science ®Google Scholar
• Simmons , J. E. , Richardson , S. D. , Speth , T. F. , Miltner , R. J. , Rice , G. , Schenck , K. M. , Hunter , S. and Teuschler , L. K. 2002 . Development of a research strategy for integrated technology-based toxicological and chemical evaluation of complex mixtures of drinking water disinfection byproducts . Environ. Health Perspect. , 110 : 1013 – 1024 .
   PubMed Web of Science ®Google Scholar
• Simmons , J. E. , Richardson , S. D. , Teuschler , L .K. , Miltner , R. J. , Speth , T. F , Schenck , K. M. , Hunter , S. and Rice , G. 2008 . The research issues underlying the Four-Lab Study: Integrated disinfection byproducts mixtures research . J. Toxicol. Environ. Health A , this issue.
   Web of Science ®Google Scholar
• Simmons , J. E. , Teuschler , L. K. and Gennings , C. 2001 . “ The toxicology of disinfection by-product mixtures: Methods for multi-chemical assessment; present research efforts; and, future research directions ” . In Microbial pathogen and disinfection by-products in drinking water: Health effects and management of risks , Edited by: Craun , G. F. , Hauchman , F. S. and Robinson , D. E. 305 – 325 . Washington, DC : ILSI Press .
   Google Scholar
• Speth , T. F. , Miltner , R. J. , Richardson , S. D. and Simmons , J. E. 2008 . Integrated disinfection by-products mixtures research: Concentration by reverse osmosis membrane techniques of disinfection byproducts from water disinfected by chlorination and ozonation/postchlorination . J. Toxicol. Environ. Health A , this issue.
   Web of Science ®Google Scholar
• U. S. Enviromental Protection Agency . 2000 . Conducting a risk assessment for mixtures of disinfection byproducts (DBPs) for drinking water treatment systems , Cincinnati, OH : U.S. Environmental Protection Agency . NCEA-C-0791.
   Google Scholar
• Villanueva , C. M. , Cantor , K. P. , Grimalt , J. O. , Malats , N. , Silverman , D. , Tardon , A. , Garcia-Closas , R. , Serra , C. , Carrato , A. , Castaño-Vinyals , G. , Marcos , R. , Rothman , N. , Real , F. X. , Dosemeci , M. and Kogevinas , M. 2007 . Bladder cancer and exposure to water disinfection by-products through ingestion, bathing, showering, and swimming in pools . Am. J. Epidemiol. , 165 : 148 – 156 .
   PubMed Web of Science ®Google Scholar
• Walgren , J. L. , Jollow , D. J. and McMillan , J. M. 2004 . Induction of peroxisome proliferation in cultured hepatocytes by a series of halogenated acetates . Toxicology , 197 : 189 – 197 .
   PubMed Web of Science ®Google Scholar
• Weinberg , H. , Krasner , S. W. , Richardson , S. D. and Thruston , A. D. Jr. The occurrence of disinfection by-products (DBPs) of health concern in drinking water: Results of a nationwide DBP occurrence study . EPA/600/R-02/068 . 2002 .
   Google Scholar
• Wong , J. S. and Gill , S. S. 2002 . Gene expression changes induced in mouse liver by di(2-ethylhexyl) phthalate . Toxicol. Appl. Pharmacol. , 185 : 180 – 196 .
   PubMed Web of Science ®Google Scholar
• Xu , Y. , Cook , T. J. and Knipp , G. T. 2005 . Effects of di-(2-ethylhexyl)-phthalate (DEHP) and its metabolites on fatty acid homeostasis regulating proteins in rat placental HRP-1 trophoblast cells . Toxicol. Sci. , 84 : 287 – 300 .
   PubMed Web of Science ®Google Scholar