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Original Articles

Thioredoxin Overexpression Modulates Remodeling Factors in Stress Responses to Cigarette Smoke

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Pages 1490-1498 | Received 02 Jun 2008, Accepted 15 Jul 2008, Published online: 03 Oct 2008

REFERENCES

  • Arner , E. S. and Holmgren , A. 2000 . Physiological functions of thioredoxin and thioredoxin reductase . Eur. J. Biochem. , 267 : 6102 – 6109 .
  • Banzet , N. , Francois , D. and Polla , B. S. 1999 . Tobacco smoke induces mitochondrial depolarization along with cell death: Effects of antioxidants . Redox. Rep. , 4 : 229 – 236 .
  • Blobe , G. C. , Schiemann , W. P. and Lodish , H. F. 2000 . Role of transforming growth factor beta in human disease . N. Engl. J. Med. , 342 : 1350 – 1358 .
  • Bove , P. F. , Wesley , U. V. , Greul , A. K. , Hristova , M. , Dostmann , W. R. and van der Vliet , A. 2007 . Nitric oxide promotes airway epithelial wound repair through enhanced activation of MMP-9 . Am. J. Respir. Cell Mol. Biol. , 36 : 138 – 146 .
  • Bradford , M. M. 1976 . A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein–dye binding . Anal. Biochem. , 72 : 248 – 254 .
  • Carnevali , S. , Petruzzelli , S. , Longoni , B. , Vanacore , R. , Barale , R. , Cipollini , M. , Scatena , F. , Paggiaro , P. , Celi , A. and Giuntini , C. 2003 . Cigarette smoke extract induces oxidative stress and apoptosis in human lung fibroblasts . Am. J. Physiol. Lung Cell Mol. Physiol. , 284 : L955 – L963 .
  • Chen , Y. , Cai , J. and Jones , D. P. 2006 . Mitochondrial thioredoxin in regulation of oxidant-induced cell death . FEBS Lett. , 580 : 6596 – 6602 .
  • Fedorov , I. A. , Wilson , S. J. , Davies , D. E. and Holgate , S. T. 2005 . Epithelial stress and structural remodelling in childhood asthma . Thorax , 60 : 389 – 394 .
  • Gartel , A. L. and Tyner , A. L. 2002 . The role of the cyclin-dependent kinase inhibitor p21 in apoptosis . Mol. Cancer Ther. , 1 : 639 – 649 .
  • Hamilton , L. M. , Torres-Lozano , C. , Puddicombe , S. M. , Richter , A. , Kimber , I. , Dearman , R. J. , Vrugt , B. , Aalbers , R. , Holgate , S. T. , Djukanovic , R. , Wilson , S. J. and Davies , D. E. 2003 . The role of the epidermal growth factor receptor in sustaining neutrophil inflammation in severe asthma . Clin. Exp. Allergy , 33 : 233 – 240 .
  • Hansen , J. M. , Go , Y. M. and Jones , D. P. 2006 . Nuclear and mitochondrial compartmentation of oxidative stress and redox signaling . Annu. Rev. Pharmacol. Toxicol. , 46 : 215 – 234 .
  • Harper , J. W. , Adami , G. R. , Wei , N. , Keyomarsi , K. and Elledge , S. J. 1993 . The p21 Cdk-interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinases . Cell , 75 : 805 – 816 .
  • Hecht , S. S. 2003 . Tobacco carcinogens, their biomarkers and tobacco-induced cancer . Nat. Rev. Caner , 3 : 733 – 744 .
  • Hellermann , G. R. , Nagy , S. B. , Kong , X. , Lockey , R. F. and Mohapatra , S. S. 2002 . Mechanism of cigarette smoke condensate-induced acute inflammatory response in human bronchial epithelial cells . Respir. Res. , 3 : 22 – 29 .
  • Hirota , K. , Nakamura , H. , Masutani , H. and Yodoi , J. 2002 . Thioredoxin superfamily and thioredoxin-inducing agents . Ann. NY Acad. Sci. , 957 : 189 – 199 .
  • Hoffmann , D. and Hoffmann , I. 1997 . The changing cigarette, 1950–1995 . J. Toxicol. Environ. Health , 50 : 307 – 364 .
  • Holmgren , A. 1985 . Thioredoxin . Annu. Rev. Biochem. , 54 : 237 – 271 .
  • Hoshino , Y. , Mio , T. , Nagai , S. , Miki , H. , Ito , I. and Izumi , T. 2001 . Cytotoxic effects of cigarette smoke extract on an alveolar type II cell-derived cell line . Am. J. Physiol. Lung Cell Mol. Biol. , 281 : L509 – L516 .
  • Hsieh , C. C. and Papaconstantinou , J. 2006 . Thioredoxin-ASK1 complex levels regulate ROS-mediated p38 MAPK pathway activity in livers of aged and long-lived Snell dwarf mice . FASEB J. , 20 : 59 – 68 .
  • James , A. L. , Pare , P. D. and Hogg , J. C. 1989 . The mechanics of airway narrowing in asthma . Am. Rev. Respir. Dis. , 139 : 242 – 246 .
  • Kaimul Ahsan , M. , Nakamura , H. , Tanito , M. , Yamada , K. , Utsumi , H. and Yodoi , J. 2005 . Thioredoxin-1 suppresses lung injury and apoptosis induced by diesel exhaust particles (DEP) by scavenging reactive oxygen species and by inhibiting DEP-induced downregulation of Akt . Free Radical Biol. Med. , 39 : 1549 – 1559 .
  • Lee , Y. J. , Kim , J. H. , Chen , J. and Song , J. J. 2002 . Enhancement of metabolic oxidative stress-induced cytotoxicity by the thioredoxin inhibitor 1-methylpropyl 2-imidazolyl disulfide is mediated through the ASK1-SEK1-JNK1 pathway . Mol. Pharmacol. , 62 : 1409 – 1417 .
  • Liu , M. , Yang , S. C. , Sharma , S. , Luo , J. , Cui , X. , Peebles , K. A. , Huang , M. , Sato , M. , Ramirez , R. D. , Shay , J. W. , Minna , J. D. and Dubinett , S. M. 2007 . EGFR signaling is required for TGF-beta 1 mediated COX-2 induction in human bronchial epithelial cells . Am. J. Respir. Cell Mol. , 37 : 578 – 588 .
  • Martin , M. D. and Matrisian , L. M. 2007 . The other side of MMPs: Protective roles in tumor progression . Cancer Metastasis Rev. , 26 : 717 – 724 .
  • Massague , J. , Blain , S. W. and Lo , R. S. 2000 . TGFbeta signaling in growth control, cancer, and heritable disorders . Cell , 103 : 295 – 309 .
  • Murillo , M. M. , del Castillo , G. , Sánchez , A. , Fernández , M. and Fabregat , I. 2005 . Involvement of EGF receptor and c-Src in the survival signals induced by TGF-beta1 in hepatocytes . Oncogene , 24 : 4580 – 4587 .
  • Nakamura , H. , Nakamura , K. and Yodoi , J. 1997 . Redox regulation of cellular activation . Annu. Rev. Immunol. , 15 : 351 – 369 .
  • Nakamura , T. , Nakamura , H. , Hoshino , T. , Ueda , S. , Wada , H. and Yodoi , J. 2005 . Redox regulation of lung inflammation by thioredoxin . Antioxid. Redox Signal. , 7 : 60 – 71 .
  • Nonn , L. , Williams , R. R. , Erickson , R. P. and Powis , G. 2003 . The absence of mitochondrial thioredoxin 2 causes massive apoptosis, exencephaly, and early embryonic lethality in homozygous mice . Mol. Cell. Biol. , 23 : 916 – 922 .
  • Ohbayashi , H. and Shimokata , K. 2005 . Matrix metalloproteinase-9 and airway remodeling in asthma . Curr. Drug Targets Inflamm. Allergy , 4 : 177 – 181 .
  • Powis , G. and Montfort , W. R. 2001 . Properties and biological activities of thioredoxins . Annu. Rev. Pharmacol. , 41 : 261 – 295 .
  • Ryter , S. W. , Kim , H. P. , Hoetzel , A. , Park , J. W. , Nakahira , K. , Wang , X. and Choi , A. M. 2007 . Mechanisms of cell death in oxidative stress . Antioxid. Redox Signal. , 9 : 49 – 89 .
  • Sato , A. , Hara , T. , Nakamura , H. , Kato , N. , Hoshino , Y. , Kondo , N. , Mishima , M. and Yodoi , J. 2006 . Thioredoxin-1 suppresses systemic inflammatory responses against cigarette smoking . Antioxid. Redox Signal. , 8 : 1891 – 1896 .
  • Sato , A. , Hoshino , Y. , Hara , T. , Muro , S. , Nakamura , H. , Mishima , M. and Yodoi , J. 2008 . Thioredoxin-1 ameliorates cigarette smoke-induced lung inflammation and emphysema in mice . J. Pharmacol. Exp. Ther. , 325 : 380 – 388 .
  • Semlali , A. , Jacques , E. , Plante , S. , Biardel , S. , Milot , J. , Laviolette , M. , Boulet , L. P. and Chakir , J. 2008 . TGF-beta suppresses EGF-induced MAPK signaling and proliferation in asthmatic epithelial cells . Am. J. Respir. Cell Mol. Biol. , 38 : 202 – 208 .
  • Seomun , Y. , Kim , J. T. and Joo , C. K. 2008 . MMP-14 mediated MMP-9 expression is involved in TGF-beta1-induced keratinocyte migration . J. Cell Biochem. , 104 : 934 – 941 .
  • Sharma , S. V. , Bell , D. W. , Settleman , J. and Haber , D. A. 2007 . Epidermal growth factor receptor mutations in lung cancer . Nat. Rev. Cancer , 7 : 169 – 181 .
  • Sheng , G. , Bernabe , K. Q. , Guo , J. and Warner , B. W. 2006 . Epidermal growth factor receptor-mediated proliferation of enterocytes requires p21waf1/cip1 expression . Gastroenterology , 131 : 153 – 164 .
  • Tesfaigzi , Y. 2006 . Roles of apoptosis in airway epithelia . Am. J. Respir. Cell Mol. Biol. , 34 : 537 – 547 .
  • Tobiume , K. , Matsuzawa , A. , Takahashi , T. , Nishitoh , H. , Morita , K. , Takeda , K. , Minowa , O. , Miyazono , K. , Noda , T. and Ichijo , H. 2001 . ASK1 is required for sustained activations of JNK/p38 MAP kinases and apoptosis . EMBO Rep. , 2 : 222 – 228 .
  • Ueno , M. , Masutani , H. , Arai , R. J. , Yamauchi , A. , Hirota , K. , Sakai , T. , Inamoto , T. , Yamaoka , Y. , Yodoi , J. and Nikaido , T. 1999 . Thioredoxin-dependent redox regulation of p53-mediated p21 activation . J. Biol. Chem. , 274 : 35809 – 35815 .
  • Uttamsingh , S. , Bao , X. , Nguyen , K. T. , Bhanot , M. , Gong , J. , Chan , J. L. , Liu , F. , Chu , T. T. and Wang , L. H. 2007 . Synergistic effect between EGF and TGF-beta1 in inducing oncogenic properties of intestinal epithelial cells . Oncogene , 27 : 2626 – 2634 .
  • Wada , T. and Penninger , J. M. 2004 . Mitogen-activated protein kinases in apoptosis regulation . Oncogene , 23 : 2838 – 2849 .
  • Wald , N. J. and Hackshaw , A. K. 1996 . Cigarette smoking: An epidemiological overview . Br. Med. Bull. , 52 : 3 – 11 .
  • Watson , W. H. , Yang , X. , Choi , Y. E. , Jones , D. P. and Kehrer , J. P. 2004 . Thioredoxin and its role in toxicology . Toxicol. Sci. , 78 : 3 – 14 .
  • Wollman , E. E. , d'Auriol , L. , Rimsky , L. , Shaw , A. , Jacquot , J. P. , Wingfield , P. , Graber , P. , Dessarps , F. , Robin , P. and Galibert , F. 1988 . Cloning and expression of a cDNA for human thioredoxin . J. Biol. Chem. , 263 : 15506 – 15512 .
  • Xiong , Y. , Hannon , G. J. , Zhang , H. , Casso , D. , Kobayashi , R. and Beach , D. 1993 . p21 is a universal inhibitor of cyclin kinases . Nature , 366 : 701 – 704 .
  • Yamada , T. , Iwasaki , Y. , Nagata , K. , Fushiki , S. , Nakamura , H. , Marunaka , Y. and Yodoi , J. 2007 . Thioredoxin-1 protects against hyperoxia-induced apoptosis in cells of the alveolar walls . Pulmon. Pharmacol. Ther. , 20 : 650 – 659 .
  • Yamasaki , M. , Kang , H. R. , Homer , R. J. , Chapoval , S. P. , Cho , S. J. , Lee , B. J. , Elias , J. A. and Lee , C. G. 2008 . P21 regulates TGF-beta1-induced pulmonary responses via a TNF-alpha-signaling pathway . Am. J. Respir. Cell Mol. Biol. , 38 : 346 – 353 .
  • Yamauchi , K. and Inoue , H. 2007 . Airway remodeling in asthma and irreversible airflow limitation-ECM deposition in airway and possible therapy for remodeling . Allergol. Int. , 56 : 321 – 329 .
  • Yao , H. , Yang , S. R. , Kode , A. , Rajendrasozhan , S. , Caito , S. , Adenuga , D. , Henry , R. , Edirisinghe , I. and Rahman , I. 2007 . Redox regulation of lung inflammation: Role of NADPH oxidase and NF-kappaB signalling . Biochem. Soc. Trans. , 35 : 1151 – 1155 .
  • Yoneda , K. , Chang , M. M. , Chmiel , K. , Chen , Y. and Wu , R. 2003 . Application of high-density DNA microarray to study smoke- and hydrogen peroxide-induced injury and repair in human bronchial epithelial cells . J. Am. Soc. Nephrol. , 14 : S284 – S289 .
  • Yoon , H. K. , Cho , H. Y. and Kleeberger , S. R. 2007 . Protective role of matrix metalloproteinase-9 in ozone-induced airway inflammation . Environ. Health Perspect. , 115 : 1557 – 1563 .
  • Yoshida , T. , Oka , S. , Masutani , H. , Nakamura , H. and Yodoi , J. 2003 . The role of thioredoxin in the aging process: Involvement of oxidative stress . Antioxid. Redox Signal. , 5 : 563 – 570 .

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