Are Atlantic Cod in Store Lungegårdsvann, a Seawater Recipient in Bergen, Affected by Environmental Contaminants? A qRT-PCR Survey

REFERENCES

• Allen , Y. , Matthiessen , P. , Scott , A. P. , Haworth , S. , Feist , S. and Thain , J. E. 1999 . The extent of oestrogenic contamination in the UK estuarine and marine environments - further surveys of flounder . Sci. Total Environ. , 233 : 5 – 20 .
   PubMed Web of Science ®Google Scholar
• Anderson , L. and Seilhamer , J. 1997 . A comparison of selected mRNA and protein abundances in human liver . Electrophoresis , 18 : 533 – 537 .
   PubMed Web of Science ®Google Scholar
• Arukwe , A. , Knudsen , F. R. and Goks⊘yr , A. 1997 . Fish zona radiata (eggshell) protein: A sensitive biomarker for environmental estrogens . Environ. Health Perspect. , 105 : 418 – 422 .
   PubMed Web of Science ®Google Scholar
• Arukwe , A. and Goks⊘yr , A. 2003 . Eggshell and egg yolk proteins in fish: hepatic proteins for the next generation: Oogenetic, population, and evolutionary implications of endocrine disruption . Comp.Hepatol. , 2 : 4
   PubMedGoogle Scholar
• Blume , J. E. and Shapiro , D. J. 1989 . Ribosome loading, but not protein-synthesis, is required for estrogen stabilization of Xenopus laevis vitellogenin messenger-RNA . Nucleic Acids Res. , 17 : 9003 – 9014 .
   PubMed Web of Science ®Google Scholar
• Bradford , M. 1976 . A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein–dye binding . Anal. Biochem , 72 : 248 – 254 .
   PubMed Web of Science ®Google Scholar
• Brammell , B. F. , Price , D. J. , Birge , W. J. and Elskus , A. A. 2004 . Apparent lack of CYP1A response to high PCB body burdens in fish from a chronically contaminated PCB site . Mar. Environ. Res. , 58 : 251 – 255 .
   PubMed Web of Science ®Google Scholar
• Brown , J. N. , Paxeus , N. , Förlin , L. and Larsson , D. G. J. 2007 . Variations in bioconcentration of human pharmaceuticals from sewage effluents into fish blood plasma . Environ. Toxicol. Pharmacol. , 24 : 267 – 274 .
   PubMed Web of Science ®Google Scholar
• Burnett , K. G. , Bain , L. J. , Baldwin , W. S. , Callard , G. V. , Cohen , S. , Di Giulio , R. T. , Evans , D. H. , Gómez-Chiarri , M. , Hahn , M. E. , Hoover , C. A. , Karchner , S. I. , Katoh , F. , MacLatchy , D. L. , Marshall , W. S. , Meyer , J. N. , Naccik , D. E. , Oleksiak , M. F. , Rees , B. B. , Singer , T. D. , Stegeman , J. J. , Towle , D. W. , Van Veld , P. A. , Vogelbein , W. K. , Whitehead , A. , Winn , R. N. and Crawford , D. L. 2007 . Fundulus as the premier teleost model in environmental biology: Opportunities for new insights using genomics . Comp. Biochem. Physiol. D Genom. Proteom. , 2 : 257 – 286 .
   PubMed Web of Science ®Google Scholar
• Cohen , A. M. , Mansour , A. A. H. and Banoub , J. H. 2005 . ‘De novo’ sequencing of Atlantic cod vitellogenin tryptic peptides by matrix-assisted laser desorption/ionization quadrupole time-of-flight tandem mass spectrometry: Similarities with haddock vitellogenin . Rapid Commun. Mass Spectrom. , 19 : 2454 – 2460 .
   PubMed Web of Science ®Google Scholar
• Corley-Smith , G. E. , Su , H. T. , Wang-Buhler , J. L. , Tseng , H. P. , Hu , C. H. , Hoang , T. , Chung , W. G. and Buhler , D. R. 2006 . CYP3C1,the first member of a new cytochrome P450 subfamily found in zebrafish (Danio rerio) . Biochem. Biophys. Res. Commun. , 340 : 1039 – 1046 .
   PubMed Web of Science ®Google Scholar
• Daughton , C. G. and Ternes , T. A. 1999 . Pharmaceuticals and personal care products in the environment: agents of subtle change? . Environ. Health Perspect. , 107 : 907 – 938 .
   PubMed Web of Science ®Google Scholar
• Desta , Z. , Zhao , X. J. , Shin , J. G. and Flockhart , D. A. 2002 . Clinical significance of the cytochrome P4502C19 genetic polymorphism . Clin. Pharmacokinet. , 41 : 913 – 958 .
   PubMed Web of Science ®Google Scholar
• Elskus , A. A. 2004 . Estradiol and estriol suppress CYP1A expression in rainbow trout primary hepatocytes . Mar. Environ. Res. , 58 : 463 – 467 .
   PubMed Web of Science ®Google Scholar
• Fent , K. , Weston , A. A. and Caminada , D. 2006 . Ecotoxicology of human pharmaceuticals . Aquat. Toxicol. , 76 : 122 – 159 .
   PubMed Web of Science ®Google Scholar
• Fossi , M. C. , Casini , S. and Marsill , L. 2007 . Potential toxicological hazard due to endocrine-disrupting chemicals on Mediterranean top predators: State of art, gender differences and methodological tools . Environ. Res. , 104 : 174 – 182 .
   PubMed Web of Science ®Google Scholar
• Goks⊘yr , A. , Andersson , T. , Hansson , T. , Klungs⊘yr , J. , Zhang , Y. and Förlin , L. 1987 . Species characteristics of the hepatic xenobiotic and steroid biotransformation systems of 2 teleost fish, Atlantic cod (Gadus morhua) and rainbow trout (Salmo gairdneri) . Toxicol. Appl. Pharmacol. , 89 : 347 – 360 .
   PubMed Web of Science ®Google Scholar
• Goks⊘yr , A. 1995 . Use of cytochrome P450 1A in fish as a biomarker of aquatic pollution . Arch. Toxicol. Suppl. , 17 : 80 – 95 .
   PubMedGoogle Scholar
• Goks⊘yr , A. 2006 . Endocrine disruptors in the marine environment: Mechanisms of toxicity and their influence on reproductive processes in fish . J. Toxicol. Environ. Health A , 69 : 175 – 184 .
   PubMed Web of Science ®Google Scholar
• Gray , E. S. , Woodin , B. R. and Stegeman , J. J. 1991 . Sex-differences in hepatic monooxygenases in winter flounder (Pseudopleuronectes americanus) and scup (Stenotomus chrysops) and regulation of P450 forms by estradiol . J. Exp. Zool. , 259 : 330 – 342 .
   PubMedGoogle Scholar
• Harvey , S. 1993 . Benzodiazepine antagonism of thyrotropin-releasing-hormone receptors—Biphasic actions on growth-hormone secretion in domestic-fowl . J. Endocrinol. , 137 : 35 – 42 .
   PubMed Web of Science ®Google Scholar
• Hasselberg , L. , Gr⊘svik , B. E. , Goks⊘yr , A. and Celander , M. C. 2005 . Interactions between xenoestrogens and ketoconazole on hepatic CYP1A and CYP3A, in juvenile Atlantic cod (Gadus morhua) . Comp. Hepatol. , 4 : 2
   PubMedGoogle Scholar
• Hemmer , M. J. , Bowman , C. J. , Hemmer , B. L. , Friedman , S. D. , Marcovich , D. , Kroll , K. J. and Denslow , N. D. 2002 . Vitellogenin mRNA regulation and plasma clearance in male sheepshead minnows, (Cyprinodon variegatus) after cessation of exposure to 17 beta-estradiol and p-nonylphenol . Aquat. Toxicol. , 58 : 99 – 112 .
   PubMed Web of Science ®Google Scholar
• Hiramatsu , N. , Cheek , A. O. , Sullivan , C. V. , Matsubara , T. and Hara , A. 2005 . “ Vitellogenesis and endocrine disruption ” . In Environmental toxicology , Edited by: Mommsen , T. P. and Moon , T. W. 431 – 471 . Amsterdam : Elsevier .
   Google Scholar
• Humbert , T. 1994 . Benzodiazepines neuroendocrine effects . Ann. Med. Psychol. , 152 : 161 – 171 .
   PubMed Web of Science ®Google Scholar
• Johnsen , T. M. , Bjerkeng , B. , Molvær , J. and Nygaard , E. Milj⊘vurdering av utfylling av sprengstein i Store Lungegårdsvann . Oslo, Norway: NIVA, Report 3927-98 . 1998 .
   Google Scholar
• Julshamn , K. , Maage , A. , Norli , H. S. , Grobecker , K. H. , Jorhem , L. and Fecher , P. 2007 . Determination of arsenic, cadmium, mercury, and lead by inductively coupled plasma/mass spectrometry in foods after pressure digestion: NMKL1 inter-laboratory study . J. Am. Off. Assoc. Chem. Int. , 90 : 844 – 856 .
   Google Scholar
• Kidd , K. A. , Blanchfield , P. J. , Mills , K. H. , Palace , V. P. , Evans , R. E. , Lazorchak , J. M. and Flick , R. W. 2007 . Collapse of a fish population after exposure to a synthetic estrogen . Proc. Natl. Acad. Sci. USA , 104 : 8897 – 8901 .
   PubMed Web of Science ®Google Scholar
• Langford , K. H. , Barron , L. and Thomas , K. V. April 2008 2008 . Determination of pharmaceutical compounds in hospital effluents and their contribution to wastewater treatment works , April 2008 , 2 – 4 . Trondheim, Norway : 2nd Norwegian Environmental Toxicology Symposium .
   Google Scholar
• Larsson , D. G. J. , Pedro , C. D. and Paxeus , N. 2007 . Effluent from drug manufactures contains extremely high levels of pharmaceuticals . J. Haz. Mater. , 148 : 751 – 755 .
   PubMed Web of Science ®Google Scholar
• Meyer , J. N. , Nacci , D. E. and Di Giulio , R. T. 2002 . Cytochrome P4501A (CYP1A) in killifish (Fundulus heteroclitus): Heritability of altered expression and relationship to survival in contaminated sediments . Toxicol. Sci. , 68 : 69 – 81 .
   PubMed Web of Science ®Google Scholar
• Metcalfe , C. D. , Metcalfe , T. L. , Kiparissis , Y. , Koenig , B. G. , Khan , C. , Hughes , R. J. , Croley , T. R. , March , R. E. and Potter , T. 2001 . Estrogenic potency of chemicals detected in sewage treatment plant effluents as determined by in vivo assays with Japanese medaka (Oryzias latipes) . Environ. Toxicol. Chem. , 20 : 297 – 308 .
   PubMed Web of Science ®Google Scholar
• Navas , J. M. and Segner , H. 2001 . Estrogen-mediated suppression of cytochrome P4501A (CYP1A) expression in rainbow trout hepatocytes: Role of estrogen receptor . Chem. Biol. Interact. , 138 : 285 – 298 .
   PubMed Web of Science ®Google Scholar
• Navas , J. M. and Segner , H. 2006 . Vitellogenin synthesis in primary cultures of fish liver cells as endpoint for in vitro screening of the (anti) estrogenic activity of chemical substances . Aquat. Toxicol. , 80 : 1 – 22 .
   PubMed Web of Science ®Google Scholar
• Nilsen , B. M. , Berg , K. and Goks⊘yr , A. 1998 . Induction of cytochrome P450 1A (CYP1A) in fish. A biomarker for environmental pollution . Methods Mol. Biol , 107 : 423 – 438 .
   PubMedGoogle Scholar
• Ohtake , F. , Takeyama , K. , Matsumoto , T. , Kitagawa , H. , Yamamoto , Y. , Nohara , K. , Tohyama , C. , Krust , A. , Mimura , J. , Chambon , P. , Yanagisawa , J. , Fujii-Kuriyama , Y. and Kato , S. 2003 . Modulation of oestrogen receptor signalling by association with the activated dioxin receptor . Nature , 423 : 545 – 550 .
   PubMed Web of Science ®Google Scholar
• Ohtake , F. , Baba , A. , Takada , I. , Okada , M. , Iwasaki , K. , Miki , H. , Takahashi , S. , Kouzmenko , A. , Nohara , K. , Chiba , T. , Fujii-Kuriyama , Y. and Kato , S. 2007 . Dioxin receptor is a ligand-dependent E3 ubiquitin ligase . Nature , 446 : 562 – 566 .
   PubMed Web of Science ®Google Scholar
• Ohtake , F. , Baba , A. , Fujii-Kuriyama , Y. and Kato , S. 2008 . Intrinsic AhR function underlies cross-talk of dioxins with sex hormone signalings . Biochem. Biophys. Res. Commun. , March 19 [Epub ahead of print]
   Web of Science ®Google Scholar
• Pait , A. S. and Nelson , J. 2002 . Endocrine disruption in fish: An assessment of recent research and results , NOAA Technical Memo. Silver Spring : NOAA, Center for Coastal Monitoring & Assessment .
   Google Scholar
• Pandelova , M. , Henkelmann , B. , Roots , O. , Simm , M. , Jaerv , L. , Benfenati , E. and Schramm , K. W. 2008 . Levels of PCDD/F and dioxin-like PCB in Baltic fish of different age and gender . Chemosphere , 71 : 369 – 378 .
   PubMed Web of Science ®Google Scholar
• Porte , C. , Janer , G. , Lorusso , L. C. , Ortiz-Zarragoitia , M. , Cajaraville , M. P. , Fossi , M. C. and Canesi , L. 2006 . Endocrine disruptors in marine organisms: Approaches and perspectives . Comp. Biochem. Physiol. C Toxicol. Pharmacol. , 143 : 303 – 315 .
   PubMed Web of Science ®Google Scholar
• Raj , A. , Peskin , C. S. , Tranchina , D. , Vargas , D. Y. and Tyagi , S. 2006 . Stochastic mRNA synthesis in mammalian cells . PLoS Biol. , 4 : 1707 – 1719 .
   Web of Science ®Google Scholar
• Reith , M. , Munholland , J. , Kelly , J. , Finn , R. N. and Fyhn , H. J. 2001 . Lipovitellins derived from two forms of vitellogenin are dif0ferentially processed during oocyte maturation in haddock (Melanogrammus aeglefinus) . J. Exp. Zool. , 291 : 58 – 67 .
   PubMedGoogle Scholar
• Roberts , P. H. and Thomas , K. V. 2006 . The occurrence of selected pharmaceuticals in wastewater effluent and surface waters of the lower Tyne catchment . Sci. Total Environ. , 356 : 143 – 153 .
   PubMed Web of Science ®Google Scholar
• Ruus , A. , Berge , J. A. , Hylland , K. , Bjerkeng , B. , Bakke , T. and Naes , K. 2006 . Polychlorinated dibenzo-p-dioxins (PCDDs) and dibenzofurans (PCDFs) in the Grenland Fjords (Norway)—Disposition, levels, and effects . J. Toxicol. Environ. Health A , 69 : 185 – 200 .
   PubMed Web of Science ®Google Scholar
• Schultz , I. R. , Orner , G. , Merdink , J. L. and Skillman , A. 2001 . Dose-response relationships and pharmacokinetics of vitellogenin in rainbow trout after intravascular administration of 17 alpha-ethynylestradiol . Aquat. Toxicol. , 51 : 305 – 318 .
   PubMed Web of Science ®Google Scholar
• Thomas , K. V. , Dye , C. , Schlabach , M. and Langford , K. H. 2007 . Source to sink tracking of selected human pharmaceuticals from two Oslo city hospitals and a wastewater treatment works . J. Environ. Monit. , 9 : 1410 – 1418 .
   PubMed Web of Science ®Google Scholar
• Towbin , H. , Staehelin , T. and Gordon , J. 1979 . Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets—Procedure and some applications . Proc. Natl. Acad. Sci. USA , 76 : 4350 – 4354 .
   PubMed Web of Science ®Google Scholar
• Trudeau , V. L. , Metcalfe , C. D. , Mimeault , C. and Moon , T. W. 2005 . “ Pharmaceuticals in the environment: Drugged fish? ” . In Environmental toxicology , Edited by: Mommsen , T. P. and Moon , T. W. 475 – 494 . Amsterdam : Elsevier .
   Google Scholar
• Tseng , H. P. , Hseu , T. H. , Buhler , D. R. , Wang , W. D. and Hu , C. H. 2005 . Constitutive and xenobiotics-induced expression of a novel CYP3A gene from zebrafish larva . Toxicol. Appl. Pharmacol. , 205 : 247 – 258 .
   PubMed Web of Science ®Google Scholar
• Vandesompele , J. , De Preter , K. , Pattyn , F. , Poppe , B. , Van Roy , N. , De Paepe , A. and Speleman , F. 2002 . Accurate normalization of real-time quantitative RT-PCR data by geometric averaging of multiple internal control genes . Genome Biol. , 3 RESEARCH0034
   PubMed Web of Science ®Google Scholar
• Weigel , S. , Berger , U. , Jensen , E. , Kallenborn , R. , Thoresen , H. and Hühnerfuss , H. 2004 . Determination of selected pharmaceuticals and caffeine in sewage and seawater from Troms⊘/Norway with emphasis on ibuprofen and its metabolites . Chemosphere , 56 : 583 – 592 .
   PubMed Web of Science ®Google Scholar