355
Views
50
CrossRef citations to date
0
Altmetric
Original Articles

Reactive Oxygen Species- and Nitric Oxide-Mediated Lung Inflammation and Mitochondrial Dysfunction in Wild-Type and iNOS-Deficient Mice Exposed to Diesel Exhaust Particles

, , , , , , & show all
Pages 560-570 | Received 20 Oct 2008, Accepted 05 Dec 2008, Published online: 06 Mar 2009

REFERENCES

  • Baulig , A. , Garlatti , M. , Bonvallot , V. , Marchand , A. , Barouki , R. , Marano , F. and Baeza-Squiban , A. 2003 . Involvement of reactive oxygen species in the metabolic pathways triggered by diesel exhaust particles in human airway epithelial cells . Am. J. Physiol. Lung Cell. Mol. Physiol. , 285 : L671 – L679 .
  • Bondy , S. C. and Naderi , S. 1994 . Contribution of hepatic cytochrome P450 systems to the generation of reactive oxygen species . Biochem. Pharmacol. , 48 : 155 – 159 .
  • Brandon , M. , Baldi , P. and Wallace , D. C. 2006 . Mitochondrial mutations in cancer . Oncogene , 25 : 4647 – 4662 .
  • Castranova , V. , Ma , J. Y , Yang , H. M. , Antonini , J. M. , Butterworth , L. , Barger , M. W. , Roberts , J. and Ma , J. K. 2001 . Effect of exposure to diesel exhaust particles on the susceptibility of the lung to infection . Environ. Health Perspect. , 109 ( Suppl. 4 ) : 609 – 612 .
  • Chung , F. 2001 . Anti-inflammatory cytokines in asthma and allergy: Interleukin-10, interleukin-12, interferon-gamma . Mediators Inflamm. , 10 : 51 – 59 .
  • Dellinger , B. P. W. 2001 . Role of free radicals in the toxicity of airborne fine particulate matter . Chem. Res. Toxicol. , 14 : 1371 – 1377 .
  • Department of Labor. Mine Safety and Health Administration . 1980 . Diesel particulate matter exposure in underground metal and non-metal mines. 30 CFR57 . Fed. Reg. , 63 : 58104 – 58148 .
  • Fisher , A. B. 1980 . Metabolism of rat granular pneumocytes isolated in primary culture . J. Appl. Physiol. Respir. Environ. Exercise Physiol. , 49 : 743 – 750 .
  • Green , D. R. and Reed , J. C. 1998 . Mitochondria and apoptosis . Science , 281 : 1309 – 1312 .
  • Health Assessment Document for Diesel Engine Exhaust . 2002 . Environmental Protection Agency, Office of Research and Development, National Center for Environmental Assessment, Washington Office Washington, DC EPA/600/8-90/057F
  • Hiura , T. S. , Kaszubowski , M. P. , Li , N. and Nel , A. E. 1999 . Chemicals in diesel exhaust particles generate reactive oxygen radicals and induce apoptosis in macrophages . J. Immunol. , 163 : 5582 – 5591 .
  • Hiura , T. S. , Li , N. , Kaplan , R. , Horwitz , M. , Seagrave , J. C. and Nel , A. E. 2000 . The role of a mitochondrial pathway in the induction of apoptosis by chemicals extracted from diesel exhaust particles . J. Immunol. , 165 : 2703 – 2711 .
  • Huang , Y. C. , Soukup , J. , Harder , S. and Becker , S. 2003 . Mitochondrial oxidant production by a pollutant dust and NO-mediated apoptosis in human alveolar macrophages . Am. J. Physiol. Cell. Physiol. , 284 : C24 – 32 .
  • Kondoh , H. , Lleonart , M. E. , Bernard , D. and Gil , J. 2007 . Protection from oxidative stress by enhanced glycolysis; A possible mechanism of cellular immortalization . Histol. Histopathol. , 22 : 85 – 90 .
  • Kumagai , Y. , Arimoto , T. , Shinyashiki , M. , Shimojo , N. , Nakai , Y. , Yoshikawa , T. and Sagai , M. 1997 . Generation of reactive oxygen species during interaction of diesel exhaust particle components with NADPH-cytochrome P450 reductase and involvement of the bioactivation in the DNA damage . Free Radical Biol. Med. , 22 : 479 – 487 .
  • Kumagai , Y. , Nakajima , H. , Midorikawa , K. , Homma-Takeda , S. and Shimojo , N. 1998 . Inhibition of nitric oxide formation by neuronal nitric oxide synthase by quinones: Nitric oxide synthase as a quinone reductase . Chem. Res. Toxicol. , 11 : 608 – 613 .
  • Kumagai , Y. , Taira , J. and Sagai , M. 1995 . Apparent inhibition of superoxide dismutase activity in vitro by diesel exhaust particles . Free Radical Biol. Med. , 18 : 365 – 371 .
  • Li , N. , Sioutas , C. , Cho , A. , Schmitz , D. , Misra , C. , Sempf , J. , Wang , M. , Oberley , T. , Froines , J. and Nel , A . 2003 . Ultrafine particulate pollutants induce oxidative stress and mitochondrial damage . Environ. Health Perspect. , 111 : 455 – 460 .
  • Lin , H. L. , Kent , U. M. , Zhang , H. , Waskell , L. and Hollenberg , P. F. 2003 . Mutation of tyrosine 190 to alanine eliminates the inactivation of cytochrome P450 2B1 by peroxynitrite . Chem. Res. Toxicol. , 16 : 129 – 136 .
  • Ma , J. Y. , Barger , M. W. , Hubbs , A. F. , Castranova , V. , Weber , S. L. and Ma , J. K. 1999 . Use of tetrandrine to differentiate between mechanisms involved in silica- versus bleomycin-induced fibrosis . J. Toxicol. Environ. Health A , 57 : 247 – 266 .
  • Otterbein , L. , Sylvester , S. L. and Choi , A. M. 1995 . Hemoglobin provides protection against lethal endotoxemia in rats: The role of heme oxygenase-1 . Am. J. Respir. Cell. Mol. Biol. , 13 : 595 – 601 .
  • Pan , C. J. , Schmitz , D. A. , Cho , A. K. , Froines , J. and Fukuto , J. M. 2004 . Inherent redox properties of diesel exhaust particles: Catalysis of the generation of reactive oxygen species by biological reductants . Toxicol. Sci. , 81 : 225 – 232 .
  • Rao , K. M. 2000 . Molecular mechanisms regulating iNOS expression in various cell types . J. Toxicol. Environ. Health B , 3 : 27 – 58 .
  • Raychaudhuri , B. , Fisher , C. J. , Farver , C. F. , Malur , A. , Drazba , J. , Kavuru , M. S. and Thomassen , M. J. 2000 . Interleukin 10 (IL-10)-mediated inhibition of inflammatory cytokine production by human alveolar macrophages . Cytokine , 12 : 1348 – 1355 .
  • Rengasamy , A. , Barger , M. W. , Kane , E. , Ma , J. K. , Castranova , V. and Ma , J. Y. 2003 . Diesel exhaust particle-induced alterations of pulmonary phase I and phase II enzymes of rats . J. Toxicol. Environ. Health A , 66 : 153 – 167 .
  • Risom , L. , Dybdahl , M. , Bornholdt , J. , Vogel , U. , Wallin , H. , Moller , P. and Loft , S. 2003 . Oxidative DNA damage and defence gene expression in the mouse lung after short-term exposure to diesel exhaust particles by inhalation . Carcinogenesis , 24 : 1847 – 1852 .
  • Sawa , T. , Akaike , T. and Maeda , H. 2000 . Tyrosine nitration by peroxynitrite formed from nitric oxide and superoxide generated by xanthine oxidase . J. Biol. Chem. , 275 : 32467 – 32474 .
  • Segal , A. W. 1989 . The electron transport chain of the microbicidal oxidase of phagocytic cells and its involvement in the molecular pathology of chronic granulomatous disease . J. Clin. Invest. , 83 : 1785 – 1793 .
  • Takano , H. , Lim , H. B. , Miyabara , Y. , Ichinose , T. , Yoshikawa , T. and Sagai , M. 1999 . Manipulation of the L-arginine-nitric oxide pathway in airway inflammation induced by diesel exhaust particles in mice . Toxicology , 139 : 19 – 26 .
  • Trinchieri , G. and Gerosa , F. 1996 . Immunoregulation by interleukin-12 . J. Leukocyte Biol. , 59 : 505 – 511 .
  • Tsurudome , Y. , Hirano , T. , Yamato , H. , Tanaka , I. , Sagai , M. , Hirano , H. , Nagata , N. , Itoh , H. and Kasai , H. 1999 . Changes in levels of 8-hydroxyguanine in DNA, its repair and OGG1 mRNA in rat lungs after intratracheal administration of diesel exhaust particles . Carcinogenesis , 20 : 1573 – 1576 .
  • White , K. A. and Marletta , M. A. 1992 . Nitric oxide synthase is a cytochrome P-450 type hemoprotein . Biochemistry , 31 : 6627 – 6631 .
  • Yang , H. M. , Antonini , J. M. , Barger , M. W. , Butterworth , L. , Roberts , B. R. , Ma , J. K. , Castranova , V. and Ma , J. Y. 2001 . Diesel exhaust particles suppress macrophage function and slow the pulmonary clearance of Listeria monocytogenes in rats . Environ. Health Perspect. , 109 : 515 – 521 .
  • Yang , H. M. , Barger , M. W. , Castranova , V. , Ma , J. K. , Yang , J. J. and Ma , J. Y. 1999 . Effects of diesel exhaust particles (DEP), carbon black, and silica on macrophage responses to lipopolysaccharide: Evidence of DEP suppression of macrophage activity . J. Toxicol. Environ. Health A , 58 : 261 – 278 .
  • Yin , X. J. , Ma , J. Y. , Antonini , J. M. , Castranova , V. and Ma , J. K. 2004 . Roles of reactive oxygen species and heme oxygenase-1 in modulation of alveolar macrophage-mediated pulmonary immune responses to Listeria monocytogenes by diesel exhaust particles . Toxicol. Sci. , 82 : 143 – 153 .
  • Yin , X. J. , Schafer , R. , Ma , J. Y. , Antonini , J. M. , Roberts , J. R. , Weissman , D. N. , Siegel , P. D. and Ma , J. K. 2003 . Alteration of pulmonary immunity to Listeria monocytogenes by diesel exhaust particles (DEPs). II. Effects of DEPs on T-cell-mediated immune responses in rats . Environ. Health Perspect. , 111 : 524 – 530 .
  • Yin , X. J. , Schafer , R. , Ma , J. Y. , Antonini , J. M. , Weissman , D. D. , Siegel , P. D. , Barger , M. W. , Roberts , J. R. and Ma , J. K. 2002 . Alteration of pulmonary immunity to Listeria monocytogenes by diesel exhaust particles (DEPs). I. Effects of DEPs on early pulmonary responses . Environ. Health Perspect. , 110 : 1105 – 1111 .
  • Zeidler , P. C. , Roberts , J. R. , Castranova , V. , Chen , F. , Butterworth , L. , Andrew , M. E. , Robinson , V. A. and Porter , D. W. 2003 . Response of alveolar macrophages from inducible nitric oxide synthase knockout or wild-type mice to an in vitro lipopolysaccharide or silica exposure . J. Toxicol. Environ. Health A , 66 : 995 – 1013 .
  • Zhao , H. , Barger , M. W. , Ma , J. K. , Castranova , V. and Ma , J. Y. 2006 . Cooperation of the inducible nitric oxide synthase and cytochrome P450 1A1 in mediating lung inflammation and mutagenicity induced by diesel exhaust particles . Environ. Health Perspect. , 114 : 1253 – 1258 .

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.