Skin Exposure to Chronic But Not Acute UV Radiation Affects Peripheral T-Cell Function

REFERENCES

• Armstrong , B. K. and Kricker , A. 2001 . The epidemiology of UV induced skin cancer . J. Photochem. Photobiol. B , 63 : 8 – 18 .
   PubMed Web of Science ®Google Scholar
• Aubin , F. 2003 . Mechanisms involved in ultraviolet light-induced immunosuppression . Eur. J. Dermatol. , 13 : 515 – 23 .
   PubMed Web of Science ®Google Scholar
• Beissert , S. and Loser , K. 2008 . Molecular and cellular mechanisms of photocarcinogenesis . Photochem. Photobiol. , 84 : 29 – 34 .
   PubMed Web of Science ®Google Scholar
• Bernstein , I. A. and Vaughan , F. L. 1999 . Cultured keratinocytes in in vitro dermatotoxicological investigation: A review . J. Toxicol. Environ. Health B , 2 : 1 – 30 .
   PubMed Web of Science ®Google Scholar
• Bikle , D. D. 2008 . Vitamin D and the immune system: Role in protection against bacterial infection . Curr. Opin. Nephrol. Hypertens. , 17 : 348 – 52 .
   PubMed Web of Science ®Google Scholar
• Byrne , S. N. and Halliday , G. M. 2005 . B cells activated in lymph nodes in response to ultraviolet irradiation or by interleukin-10 inhibit dendritic cell induction of immunity . J. Invest. Dermatol. , 124 : 570 – 78 .
   PubMedGoogle Scholar
• Byrne , S. N. , Limon-Flores , A. Y. and Ullrich , S. E. 2008 . Mast cell migration from the skin to the draining lymph nodes upon ultraviolet irradiation represents a key step in the induction of immune suppression . J. Immunol. , 180 : 4648 – 55 .
   PubMed Web of Science ®Google Scholar
• Byrne , S. N. , Spinks , N. and Halliday , G. M. 2002 . Ultraviolet a irradiation of C57BL/6 mice suppresses systemic contact hypersensitivity or enhances secondary immunity depending on dose . J. Invest. Dermatol. , 119 : 858 – 64 .
   PubMed Web of Science ®Google Scholar
• Chesney , R. W. 2010 . Vitamin D and The Magic Mountain: The anti-infectious role of the vitamin . J. Pediatr. , 156 : 698 – 703 .
   PubMed Web of Science ®Google Scholar
• El-Abaseri , T. B. , Putta , S. and Hansen , L. A. 2006 . Ultraviolet irradiation induces keratinocyte proliferation and epidermal hyperplasia through the activation of the epidermal growth factor receptor . Carcinogenesis , 27 : 225 – 231 .
   PubMed Web of Science ®Google Scholar
• Fisher , M. S. and Kripke , M. L. 1978 . Further studies on the tumor-specific suppressor cells induced by ultraviolet radiation . J. Immunol. , 121 : 1139 – 44 .
   PubMed Web of Science ®Google Scholar
• Gonzalez Maglio , D. H. , Paz , M. L. , Ferrari , A. , Weill , F. S. , Czerniczyniec , A. , Leoni , J. and Bustamante , J. 2005 . Skin damage and mitochondrial dysfunction after acute ultraviolet B irradiation: Relationship with nitric oxide production . Photodermatol. Photoimmunol. Photomed. , 21 : 311 – 17 .
   PubMedGoogle Scholar
• Gonzalez Maglio , D. H. , Paz , M. L. , Ferrari , A. , Weill , F. S. , Nieto , J. and Leoni , J. 2010 . Alterations in skin immune response throughout chronic UVB irradiation—Skin cancer development and prevention by naproxen . Photochem. Photobiol. , 86 : 146 – 152 .
   PubMed Web of Science ®Google Scholar
• Gorman , S. , Tan , J. W. , Yerkovich , S. T. , Finlay-Jones , J. J. and Hart , P. H. 2007 . CD4+ T cells in lymph nodes of UVB-irradiated mice suppress immune responses to new antigens both in vitro and in vivo . J. Invest. Dermatol. , 127 : 915 – 24 .
   PubMedGoogle Scholar
• Greene , M. I. , Sy , M. S. , Kripke , M. and Benacerraf , B. 1979 . Impairment of antigen-presenting cell function by ultraviolet radiation . Proc. Natl. Acad. Sci. USA , 76 : 6591 – 95 .
   PubMed Web of Science ®Google Scholar
• Gurish , M. F. , Lynch , D. H. and Daynes , R. A. 1982 . Changes in antigen-presenting cell function in the spleen and lymph nodes of ultraviolet-irradiated mice . Transplantation , 33 : 280 – 84 .
   PubMed Web of Science ®Google Scholar
• Halliday , G. M. and Rana , S. 2008 . Waveband and dose dependency of sunlight-induced immunomodulation and cellular changes . Photochem. Photobiol. , 84 : 35 – 46 .
   PubMed Web of Science ®Google Scholar
• Jameson , J. , Ugarte , K. , Chen , N. , Yachi , P. , Fuchs , E. , Boismenu , R. and Havran , W. L. 2002 . A role for skin gammadelta T cells in wound repair . Science , 296 : 747 – 49 .
   PubMed Web of Science ®Google Scholar
• Jontell , M. , Eklof , C. , Dahlgren , U. I. and Bergenholtz , G. 1994 . Difference in capacity between macrophages and dendritic cells from rat incisor pulp to provide accessory signals to concanavalin-A-stimulated T-lymphocytes . J. Dent. Res. , 73 : 1056 – 60 .
   PubMedGoogle Scholar
• Kaminski , M. J. , Cruz , P. D. Jr. , Bergstresser , P. R. and Takashima , A. 1993 . Killing of skin-derived tumor cells by mouse dendritic epidermal T-cells . Cancer Res. , 53 : 4014 – 19 .
   PubMed Web of Science ®Google Scholar
• Kruisbeek , A. M. , Shevach , E. and Thornton , A. M. 2004 . Proliferative assays for T cell function . Curr. Protocol Immunol. , 3 : 3 – 12 . Unit
   Google Scholar
• Loser , K. , Apelt , J. , Voskort , M. , Mohaupt , M. , Balkow , S. , Schwarz , T. , Grabbe , S. and Beissert , S. 2007 . IL-10 controls ultraviolet-induced carcinogenesis in mice . J. Immunol. , 179 : 365 – 71 .
   PubMed Web of Science ®Google Scholar
• Loser , K. and Beissert , S. 2009 . Regulation of cutaneous immunity by the environment: An important role for UV irradiation and vitamin D . Int. Immunopharmacol. , 9 : 587 – 89 .
   PubMed Web of Science ®Google Scholar
• McLoone , P. , Woods , G. M. and Norval , M. 2005 . Decrease in langerhans cells and increase in lymph node dendritic cells following chronic exposure of mice to suberythemal doses of solar simulated radiation . Photochem. Photobiol. , 81 : 1168 – 73 .
   PubMed Web of Science ®Google Scholar
• Miller , J. and Gallo , R. L. 2010 . Vitamin D and innate immunity . Dermatol. Ther. , 23 : 13 – 22 .
   PubMed Web of Science ®Google Scholar
• Mulero , M. , Romeu , M. , Giralt , M. , Folch , J. , Nogues , M. R. , Fortuno , A. , Sureda , F. X. , Linares , V. , Cabre , M. , Paternain , J. L. and Mallol , J. 2006 . Oxidative stress-related markers and Langerhans cells in a hairless rat model exposed to UV radiation . J. Toxicol. Environ. Health A , 69 : 1371 – 85 .
   PubMed Web of Science ®Google Scholar
• Paz , M. L. , Ferrari , A. , Weill , F. S. , Leoni , J. and Maglio , D. H. 2008a . Time-course evaluation and treatment of skin inflammatory immune response after ultraviolet B irradiation . Cytokine , 44 : 70 – 77 .
   PubMedGoogle Scholar
• Paz , M. L. , González Maglio , D. H. , Weill , F. S. , Bustamante , J. and Leoni , J. 2008b . Mitochondrial dysfunction and cellular stress progression after ultraviolet B irradiation in human keratinocytes . Photodermatol. Photoimmunol. Photomed. , 24 : 115 – 22 .
   PubMedGoogle Scholar
• Schwarz , A. , Maeda , A. , Wild , M. K. , Kernebeck , K. , Gross , N. , Aragane , Y. , Beissert , S. , Vestweber , D. and Schwarz , T. 2004 . Ultraviolet radiation-induced regulatory T cells not only inhibit the induction but can suppress the effector phase of contact hypersensitivity . J. Immunol. , 172 : 1036 – 43 .
   PubMed Web of Science ®Google Scholar
• Schwarz , T. 2008 . 25 years of UV-induced immunosuppression mediated by T cells—From disregarded T suppressor cells to highly respected regulatory T cells . Photochem. Photobiol. , 84 : 10 – 18 .
   PubMed Web of Science ®Google Scholar
• Shreedhar , V. , Giese , T. , Sung , V. W. and Ullrich , S. E. 1998 . A cytokine cascade including prostaglandin E2, IL-4, and IL-10 is responsible for UV-induced systemic immune suppression . J. Immunol. , 160 : 3783 – 89 .
   PubMed Web of Science ®Google Scholar
• Sleijffers , A. , Garssen , J. and Van Loveren , H. 2002 . Ultraviolet radiation, resistance to infectious diseases, and vaccination responses . Methods , 28 : 111 – 21 .
   PubMed Web of Science ®Google Scholar
• Svobodova , A. , Walterova , D. and Vostalova , J. 2006 . Ultraviolet light induced alteration to the skin . Biomed. Papers Med. Fac. Univ. Palacky Olomouc Czech Repub. , 150 : 25 – 38 .
   PubMedGoogle Scholar
• Tong , Y. , Smith , M. A. and Tucker , S. B. 1997 . Chronic ultraviolet exposure-induced p53 gene alterations in Sencar mouse skin carcinogenesis model . J. Toxicol. Environ. Health , 51 : 219 – 34 .
   PubMed Web of Science ®Google Scholar
• Ullrich , S. E. and Kripke , M. L. 1984 . Mechanisms in the suppression of tumor rejection produced in mice by repeated UV irradiation . J. Immunol. , 133 : 2786 – 90 .
   PubMedGoogle Scholar
• Ward , M. D. , Sailstad , D. M. , Andrews , D. L. , Boykin , E. H. and Selgrade , M. K. 2004 . Ultraviolet radiation downregulates allergy in BALB/c mice . J. Toxicol. Environ. Health A , 67 : 73 – 85 .
   PubMed Web of Science ®Google Scholar