Omic Approaches in Environmental Issues

REFERENCES

• Abbas , I. , Garcon , G. , Saint-Georges , F. , Billet , S. , Verdin , A. , Gosset , P. , Mulliez , P. and Shirali , P. 2010 . Occurrence of molecular abnormalities of cell cycle in L132 cells after in vitro short-term exposure to air pollution PM(2.5) . Chem. Biol. Interact , 188 : 558 – 65 .
   PubMed Web of Science ®Google Scholar
• Alban , A. , David , S. O. , Bjorkesten , L. , Andersson , C. , Sloge , E. , Lewis , S. and Currie , I. 2003 . A novel experimental design for comparative two-dimensional gel analysis: two-dimensional difference gel electrophoresis incorporating a pooled internal standard . Proteomics , 3 : 36 – 44 .
   PubMed Web of Science ®Google Scholar
• Anderson , R. B. , Cianciolo , G. J. , Kennedy , M. N. and Pizzo , S. V. 2008 . Alpha 2-macroglobulin binds CpG oligodeoxynucleotides and enhances their immunostimulatory properties by a receptor-dependent mechanism . J. Leukocyte Biol , 83 : 381 – 92 .
   PubMed Web of Science ®Google Scholar
• Araujo , J. A. 2010 . “ Particulate air pollution, systemic oxidative stress, inflammation, and atherosclerosis ” . In Air Qual Atmos Health , Springer .
   Google Scholar
• Avery , A. M. , Willetts , S. A. and Avery , S. V. 2004 . Genetic dissection of the phospholipid hydroperoxidase activity of yeast gpx3 reveals its functional importance . J. Biol. Chem , 279 : 46652 – 58 .
   PubMed Web of Science ®Google Scholar
• Berntssen , M. H. , Aspholm , O. O. , Hylland , K. , Wendelaar Bonga , S. E. and Lundebye , A. K. 2001 . Tissue metallothionein, apoptosis and cell proliferation responses in Atlantic salmon (Salmo salar L.) parr fed elevated dietary cadmium . Comp. Biochem. Physiol. C Toxicol. Pharmacol , 128 : 299 – 310 .
   PubMed Web of Science ®Google Scholar
• Bierl , C. , Voetsch , B. , Jin , R. C. , Handy , D. E. and Loscalzo , J. 2004 . Determinants of human plasma glutathione peroxidase (GPx-3) expression . J. Biol. Chem , 279 : 26839 – 45 .
   PubMed Web of Science ®Google Scholar
• Bonilla-Valverde , D. , Ruiz-Laguna , J. , Munoz , A. , Ballesteros , J. , Lorenzo , F. , Gomez-Ariza , J. L. and Land opez-Barea , J. 2004 . Evolution of biological effects of Aznalcollar mining spill in the Algerian mouse (Mus spretus) using biochemical biomarkers . Toxicology , 197 : 123 – 38 .
   PubMed Web of Science ®Google Scholar
• Bouraoui , Z. , Banni , M. , Chouba , L. , Ghedira , J. , Clerandeau , C. , Jebali , J. , Narbonne , J. F. and Boussetta , H. 2010 . Monitoring pollution in Tunisian coasts using a scale of classification based on biochemical markers in worms Nereis (Hediste) diversicolor . Environ. Monit. Assess , 164 : 691 – 700 .
   PubMed Web of Science ®Google Scholar
• Bouraoui , Z. , Banni , M. , Ghedira , J. , Clerandeau , C. , Narbonne , J. F. and Boussetta , H. 2009 . Evaluation of enzymatic biomarkers and lipoperoxidation level in Hediste diversicolor exposed to copper and benzo[a]pyrene . Ecotoxicol. Environ. Safety , 72 : 1893 – 98 .
   PubMed Web of Science ®Google Scholar
• Bradford , M. M. 1976 . A rapid and sensitive method fopr quantitation of microgram quantities of protein utilizing the principle of protein-dye binding . Ann. Biochem , 72 : 248 – 54 .
   Web of Science ®Google Scholar
• Brook , R. D. 2008 . Cardiovascular effects of air pollution . Clin. Sci. (Lond.) , 115 : 175 – 87 .
   PubMed Web of Science ®Google Scholar
• Chabicovsky , M. , Herkner , K. and Rossmanith , W. 2003 . Overexpression of activin beta(C) or activin beta(E) in the mouse liver inhibits regenerative deoxyribonucleic acid synthesis of hepatic cells . Endocrinology , 144 : 3497 – 504 .
   PubMed Web of Science ®Google Scholar
• Diatchenko , L. , Lau , Y. F. , Campbell , A. P. , Chenchik , A. , Moqadam , F. , Huang , B. , Lukyanov , S. , Lukyanov , K. , Gurskaya , N. , Sverdlov , E. D. and Siebert , P. D . 1996 . Suppression subtractive hybridization: A method for generating differentially regulated or tissue-specific cDNA probes and libraries . Proc. Natl. Acad. Sci. USA , 93 : 6025 – 30 .
   PubMed Web of Science ®Google Scholar
• Fedorenkova , A. , Vonk , J. A. , Lenders , H. J. , Ouborg , N. J. , Breure , A. M. and Hendriks , A. J. 2010 . Ecotoxicogenomics: Bridging the gap between genes and populations . Environ. Sci. Technol , 44 : 4328 – 33 .
   PubMed Web of Science ®Google Scholar
• Fliser , D. , Novak , J. , Thongboonkerd , V. , Argiles , A. , Jankowski , V. , Girolami , M. A. , Jankowski , J. and Mischak , H. 2007 . Advances in urinary proteome analysis and biomarker discovery . J. Am. Soc. Nephrol , 18 : 1057 – 71 .
   PubMed Web of Science ®Google Scholar
• Gabrielsen , B. O. and Opstvedt , J. 1980 . A biological assay for determination of availability of selenium for restoring blood plasma gluthathione peroxidase activity in selenium-depleted chicks . J. Nutr , 110 : 1089 – 95 .
   PubMed Web of Science ®Google Scholar
• Galloway , T. S. and Depledge , M. H. 2001 . Immunotoxicity in invertebrates: Measurement and ecotoxicological relevance . Ecotoxicology , 10 : 5 – 23 .
   PubMed Web of Science ®Google Scholar
• Gatehouse , H. S. , Markwick , N. P. , Poulton , J. , Ward , V. K. , Young , V. , Wilson , S. , Dellow , R. , Sneddon , K. , Gatehouse , L. N. , Simpson , R. M. , Janssen , B. J. , Bishop , R. and Schaffer , R. J. 2007 . Effects of EPPONPV infection on gene expression in Epiphyas postvittana larvae . N. Z. Plant Protect , 30 : 33 – 41 .
   Google Scholar
• Gomez-Ariza , J. L. , Gonzalez-Fernandez , M. , Garcia-Barrera , T. , Lopez-Barea , J. and Pueyo , C. 2008 . Integration of metallomics, proteomics and transcriptomics in environmental issues . Chem. Listy , 102 : s303 – 8 .
   Google Scholar
• Gonzalez-Fernandez , M. , Garcia-Barrera , T. , Arias-Borrego , A. , Jurado , J. , Pueyo , C. , Lopez-Barea , J. and Gomez-Ariza , J. L. 2009 . Metallomics integrated with proteomics in deciphering metal-related environmental issues . Biochimie , 91 : 1311 – 17 .
   PubMed Web of Science ®Google Scholar
• Gonzalez-Fernandez , M. , Garcia-Barrera , T. , Jurado , J. , Prieto-Álamo , M. J. , Pueyo , C. , Lopez-Barea , J. and Gomez-Ariza , J. L. 2008 . Integrated application of transcriptomics, proteomics and metallomics in environmental studies . Pure Appl. Chem , 12 : 2609 – 26 .
   Google Scholar
• Greene , C. M. and McElvaney , N. G. 2009 . Proteases and antiproteases in chronic neutrophilic lung disease—Relevance to drug discovery . Br. J. Pharmacol , 158 : 1048 – 58 .
   PubMed Web of Science ®Google Scholar
• Hashimoto , O. , Sekiyama , K. , Matsuo , T. and Hasegawa , Y. 2009 . Implication of activin E in glucose metabolism: Transcriptional regulation of the inhibin/activin betaE subunit gene in the liver . Life Sci , 85 : 534 – 40 .
   PubMed Web of Science ®Google Scholar
• Hines , A. , Oladiran , G. S. , Bignell , J. P. , Stentiford , G. D. and Viant , M. R. 2007 . Direct sampling of organisms from the field and knowledge of their phenotype: Key recommendations for environmental metabolomics . Environ. Sci. Technol , 41 : 3375 – 81 .
   PubMed Web of Science ®Google Scholar
• Ho , A. S. , Cheng , C. C. , Lee , S. C. , Liu , M. L. , Lee , J. Y. , Wang , W. M. and Wang , C. C. 2010 . Novel biomarkers predict liver fibrosis in hepatitis C . J. Biomed. Sci , 17 : 58
   PubMed Web of Science ®Google Scholar
• Hu , Y. , Malone , J. P. , Fagan , A. M. , Townsend , R. R. and Holtzman , D. M. 2005 . Comparative proteomic analysis of intra- and interindividual variation in human cerebrospinal fluid . Mol. Cell. Proteomics , 4 : 2000 – 9 .
   PubMed Web of Science ®Google Scholar
• Hui , X. , Zhu , W. , Wang , Y. , Lam , K. S. , Zhang , J. , Wu , D. , Kraegen , E. W. , Li , Y. and Xu , A. 2009 . Major urinary protein-1 increases energy expenditure and improves glucose intolerance through enhancing mitochondrial function in skeletal muscle of diabetic mice . J. Biol. Chem , 284 : 14050 – 57 .
   PubMed Web of Science ®Google Scholar
• Jiang , N. , Thangamani , S. , Chor , C. F. , Wang , S. Y. , Winarsih , I. , Du , R. J. , Sivaraman , J. , Ho , B. and Ding , J. L. 2009 . A novel serine protease inhibitor acts as an immunomodulatory switch while maintaining homeostasis . J. Innate Immun , 1 : 465 – 79 .
   PubMed Web of Science ®Google Scholar
• Kondo , T. 2008 . Tissue proteomics for cancer biomarker development: Laser microdissection and 2D-DIGE . BMB Rep , 41 : 626 – 34 .
   PubMed Web of Science ®Google Scholar
• LaMarre , J. , Wollenberg , G. K. , Gonias , S. L. and Hayes , M. A. 1991 . Cytokine binding and clearance properties of proteinase-activated alpha 2-macroglobulins . Lab. Invest , 65 : 3 – 14 .
   PubMed Web of Science ®Google Scholar
• Lee , S. Y. , Lee , B. L. and Soderhall , K. 2004 . Processing of crayfish hemocyanin subunits into phenoloxidase . Biochem. Biophys. Res. Commun , 322 : 490 – 96 .
   PubMed Web of Science ®Google Scholar
• Leong , M. L. , Maiyar , A. C. , Kim , B. , O'Keeffe , B. A. and Firestone , G. L. 2003 . Expression of the serum- and glucocorticoid-inducible protein kinase, Sgk, is a cell survival response to multiple types of environmental stress stimuli in mammary epithelial cells . J. Biol. Chem , 278 : 5871 – 82 .
   PubMed Web of Science ®Google Scholar
• Leoni , S. , Torrice , A. , Chiuchiarelli , G. , Bruscalupi , G. and Cristaldi , M. 2008 . Cell-cycle protein modifications in the kidney of Mus spretus from Donana National Park . Environ. Toxicol , 23 : 44 – 51 .
   PubMed Web of Science ®Google Scholar
• Lettieri , T. 2006 . Recent applications of DNA microarray technology to toxicology and ecotoxicology . Environ. Health Perspect , 114 : 4 – 9 .
   PubMed Web of Science ®Google Scholar
• Levicar , N. , Dewey , R. A. , Daley , E. , Bates , T. E. , Davies , D. , Kos , J. , Pilkington , G. J. and Lah , T. T. 2003 . Selective suppression of cathepsin L by antisense cDNA impairs human brain tumor cell invasion in vitro and promotes apoptosis . Cancer Gene Ther , 10 : 141 – 51 .
   PubMed Web of Science ®Google Scholar
• Lindon , J. C. , Keun , H. C. , Ebbels , T. M. , Pearce , J. M. , Holmes , E. and Nicholson , J. K. 2005 . The Consortium for Metabonomic Toxicology (COMET): Aims, activities and achievements . Pharmacogenomics , 6 : 691 – 99 .
   PubMed Web of Science ®Google Scholar
• Loffing , J. , Flores , S. Y. and Staub , O. 2006 . Sgk kinases and their role in epithelial transport . Annu. Rev. Physiol , 68 : 461 – 90 .
   PubMed Web of Science ®Google Scholar
• Luebke , R. W. , Chen , D. H. , Dietert , R. , Yang , Y. , King , M. and Luster , M. I. 2006 . The comparative immunotoxicity of five selected compounds following developmental or adult exposure . J. Toxicol. Environ. Health B , 9 : 1 – 26 .
   PubMed Web of Science ®Google Scholar
• Luna-Acosta , A. , Rosenfeld , E. , Amari , M. , Fruitier-Arnaudin , I. , Bustamante , P. and Thomas-Guyon , H. 2010 . First evidence of laccase activity in the Pacific oyster Crassostrea gigas . Fish Shellfish Immunol , 28 : 719 – 26 .
   PubMed Web of Science ®Google Scholar
• Lutz , J. , Thurmel , K. and Heemann , U. 2010 . Anti-inflammatory treatment strategies for ischemia/reperfusion injury in transplantation . J. Inflamm. (Lond.) , 7 : 27
   PubMed Web of Science ®Google Scholar
• Machreki-Ajmi , M. , Ketata , I. , Ladhar-Chaabouni , R. and Hamza-Chaffai , A . 2008 . The effect of in situ cadmium contamination on some biomarkers in Cerastoderma glaucum . Ecotoxicology , 17 : 1 – 11 .
   PubMed Web of Science ®Google Scholar
• Mahler , K. L. , Fleming , J. L. , Dworkin , A. M. , Gladman , N. , Cho , H. Y. , Mao , J. H. , Balmain , A. and Toland , A. E . 2008 . Sequence divergence of Mus spretus and Mus musculus across a skin cancer susceptibility locus . BMC Genomics , 9 : 626
   PubMed Web of Science ®Google Scholar
• Manzanares , W. , Biestro , A. , Galusso , F. , Torre , M. H. , Manay , N. , Pittini , G. , Facchin , G. and Hardy , G. 2009 . Serum selenium and glutathione peroxidase-3 activity: Biomarkers of systemic inflammation in the critically ill? . Intensive Care Med , 35 : 882 – 89 .
   PubMed Web of Science ®Google Scholar
• Menzel , R. , Swain , S. C. , Hoess , S. , Claus , E. , Menzel , S. , Steinberg , C. E. , Reifferscheid , G. and Sturzenbaum , S. R. 2009 . Gene expression profiling to characterize sediment toxicity—A pilot study using Caenorhabditis elegans whole genome microarrays . BMC Genomics , 10 : 160
   PubMed Web of Science ®Google Scholar
• Montes-Nieto , R. , Fuentes-Almagro , C. A. , Bonilla-Valverde , D. , Prieto-Alamo , M. J. , Jurado , J. , Carrascal , M. , Gomez-Ariza , J. L. , Lopez-Barea , J. and Pueyo , C. 2007 . Proteomics in free-living Mus spretus to monitor terrestrial ecosystems . Proteomics , 7 : 4376 – 87 .
   PubMed Web of Science ®Google Scholar
• Montes-Nieto , R. , Garcia-Barrera , T. , Gomez-Ariza , J. L. and Lopez-Barea , J. 2010 . Environmental monitoring of Domingo Rubio stream (Huelva Estuary, SW Spain) by combining conventional biomarkers and proteomic analysis in Carcinus maenas . Environ. Pollut , 158 : 401 – 8 .
   PubMed Web of Science ®Google Scholar
• PNUE/COI/AIEA/FAO . 1994 . Programme de surveillance continue des contaminants utilisant des organismes marins: Assurance de la qualité et bonnes pratiques au laboratoire . Méthodes de références pour les études de la pollution marine , 57 : 25
   Google Scholar
• Poynton , H. C. and Vulpe , C. D. 2009 . Ecotoxicogenomics: Emerging technologies for emerging contaminants . J. Am. Water Resources Assoc , 45 : 83 – 96 .
   Web of Science ®Google Scholar
• Prieto-Alamo , M. J. , Abril , N. , Osuna-Jimenez , I. and Pueyo , C. 2009 . Solea senegalensis genes responding to lipopolysaccharide and copper sulphate challenges: Large-scale identification by suppression subtractive hybridization and absolute quantification of transcriptional profiles by real-time RT-PCR . Aquat. Toxicol , 91 : 312 – 19 .
   PubMed Web of Science ®Google Scholar
• Prieto-Alamo , M. J. , Cabrera-Luque , J. M. and Pueyo , C. 2003 . Absolute quantitation of normal and ROS-induced patterns of gene expression: An in vivo real-time PCR study in mice . Gene Expression , 11 : 23 – 34 .
   PubMed Web of Science ®Google Scholar
• Reddy , P. S. , Tuberty , S. R. and Fingerman , M. 1997 . Effects of cadmium and mercury on ovarian maturation in the red swamp crayfish, Procambarus clarkii . Ecotoxicol Environ Saf , 37 : 62 – 65 .
   PubMed Web of Science ®Google Scholar
• Rioboo , C. , O'Connor , J. E. , Prado , R. , Herrero , C. and Cid , A. 2009 . Cell proliferation alterations in Chlorella cells under stress conditions . Aquat. Toxicol , 94 : 229 – 37 .
   PubMed Web of Science ®Google Scholar
• Rister , M. and Baehner , R. L. 1976 . The alteration of superoxide dismutase, catalase, glutathione peroxidase, and NAD(P)H cytochrome c reductase in guinea pig polymorphonuclear leukocytes and alveolar macrophages during hyperoxia . J. Clin. Invest , 58 : 1174 – 84 .
   PubMed Web of Science ®Google Scholar
• Romero-Ruiz , A. , Carrascal , M. , Alhama , J. , Gomez-Ariza , J. L. , Abian , J. and Lopez-Barea , J. 2006 . Utility of proteomics to assess pollutant response of clams from the Donana bank of Guadalquivir Estuary (SW Spain) . Proteomics , 6 ( suppl. 1 ) : S245 – 55 .
   Google Scholar
• Rossini Oliva , S. and Mingorance , M. D. 2004 . Study of the impact of industrial emission on the vegetation grown around Huelva (South of Spain) City . J. Atmos. Chem , 49 : 291 – 302 .
   Web of Science ®Google Scholar
• Ruiz-Laguna , J. , Abril , N. , Garcia-Barrera , T. , Gomez-Ariza , J. L. , Lopez-Barea , J. and Pueyo , C. 2006 . Absolute transcript expression signatures of Cyp and Gst genes in Mus spretus to detect environmental contamination . Environ. Sci. Technol , 40 : 3646 – 52 .
   PubMed Web of Science ®Google Scholar
• Ruiz-Laguna , J , Abril , N , Prieto-Alamo , MJ , Lopez-Barea , J and Pueyo , C . 2005 . Tissue, species, and environmental differences in absolute quantities of murine mRNAs coding for alpha, mu, omega, pi, and theta glutathione S-transferases . Gene Expression , 12 : 165 – 176 .
   PubMed Web of Science ®Google Scholar
• Sagone , A. L. Jr. , Husney , R. M. , O'Dorisio , M. S. and Metz , E. N. 1984 . Mechanisms for the oxidation of reduced gluthathione by stimulated granulocytes . Blood , 63 : 96 – 104 .
   PubMed Web of Science ®Google Scholar
• Salnikow , K. , Davidson , T. , Zhang , Q. , Chen , L. C. , Su , W. and Costa , M. 2003 . The involvement of hypoxia-inducible transcription factor-1-dependent pathway in nickel carcinogenesis . Cancer Res , 63 : 3524 – 30 .
   PubMed Web of Science ®Google Scholar
• Sawyer , K. , Mundandhara , S. , Ghio , A. J. and Madden , M. C. 2010 . The effects of ambient particulate matter on human alveolar macrophage oxidative and inflammatory responses . J. Toxicol. Environ. Health A , 73 : 41 – 57 .
   PubMed Web of Science ®Google Scholar
• Schlitt , T. and Kemmeren , P. 2004 . From microarray data to results. Workshop on genomic approaches to microarray data analysis . EMBO Rep , 5 : 459 – 63 .
   PubMed Web of Science ®Google Scholar
• Sellers , T. A. and Yates , J. R . 2003 . Review of proteomics with applications to genetic epidemiology . Genet. Epidemiol , 24 : 83 – 98 .
   PubMed Web of Science ®Google Scholar
• Serhan , C. N. and Chiang , N. 2008 . Endogenous pro-resolving and anti-inflammatory lipid mediators: a new pharmacologic genus . Br. J. Pharmacol , 153 ( suppl. 1 ) : S200 – 15 .
   PubMed Web of Science ®Google Scholar
• Shuhui , L. , Mok , Y. K. and Wong , W. S. 2009 . Role of mammalian chitinases in asthma . Int. Arch. Allergy Immunol , 149 : 369 – 77 .
   PubMed Web of Science ®Google Scholar
• Sies , H. 1993 . Strategies of antioxidant defense . Eur. J. Biochem , 215 : 213 – 19 .
   PubMedGoogle Scholar
• Smaoui-Damak , W. , Berthet , B. and Hamza-Chaffai , A. 2009 . In situ potential use of metallothionein as a biomarker of cadmium contamination in Ruditapes decussatus . Ecotoxicol. Environ. Safety , 72 : 1489 – 98 .
   PubMed Web of Science ®Google Scholar
• Snell , T. W. , Brogdon , S. E. and Morgan , M. B . 2003 . Gene expression profiling in ecotoxicology . Ecotoxicology , 12 : 475 – 83 .
   PubMed Web of Science ®Google Scholar
• Soderhall , K. and Cerenius , L. 1998 . Role of the prophenoloxidase-activating system in invertebrate immunity . Curr. Opin. Immunol , 10 : 23 – 28 .
   PubMed Web of Science ®Google Scholar
• Song , H. M. , Jang , A. S. , Ahn , M. H. , Takizawa , H. , Lee , S. H. , Kwon , J. H. , Lee , Y. M,. , Rhim , T. Y. and Park , C. S. 2008 . Ym1 and Ym2 expression in a mouse model exposed to diesel exhaust particles . Environ. Toxicol , 23 : 110 – 16 .
   PubMed Web of Science ®Google Scholar
• Stewart , A. G. 2009 . Mediators and receptors in the resolution of inflammation: drug targeting opportunities . Br. J. Pharmacol , 158 : 933 – 35 .
   PubMed Web of Science ®Google Scholar
• Suarez-Serrano , A. , Alcaraz , C. , Ibanez , C. , Trobajo , R. and Barata , C. 2010 . Procambarus clarkii as a bioindicator of heavy metal pollution sources in the lower Ebro River and Delta . Ecotoxicol. Environ. Safety , 73 : 280 – 86 .
   PubMed Web of Science ®Google Scholar
• Tastet , C. , Lescuyer , P. , Diemer , H. , Luche , S. , van Dorsselaer , A. and Rabilloud , T. 2003 . A versatile electrophoresis system for the analysis of high- and low-molecular-weight proteins . Electrophoresis , 24 : 1787 – 94 .
   PubMed Web of Science ®Google Scholar
• Tong , X. , Muchnik , M. , Chen , Z. , Patel , M. , Wu , N. , Joshi , S. , Rui , L. , Lazar , M. A. and Yin , L. 2010 . Transcriptional repressor E4-binding protein 4 (E4BP4) regulates metabolic hormone fibroblast growth factor 21 (FGF21) during circadian cycles and feeding . J. Biol. Chem , 285 : 36401 – 9 .
   PubMed Web of Science ®Google Scholar
• Ulrich , M. M. , Alink , G. M. , Kumarathasan , P. , Vincent , R. , Boere , A. J. F. and Cassee , F. R. 2002 . Health effects and time course of particulate matter on the cardiopulmonary system in rats with lung inflammation . J. Toxicol. Environ. Health A , 65 : 1571 – 95 .
   PubMed Web of Science ®Google Scholar
• Vejda , S. , Erlach , N. , Peter , B. , Drucker , C. , Rossmanith , W. , Pohl , J. , Schulte-Hermann , R. and Grusch , M. 2003 . Expression of activins C and E induces apoptosis in human and rat hepatoma cells . Carcinogenesis , 24 : 1801 – 9 .
   PubMed Web of Science ®Google Scholar
• Villarreal-Calderon , R. , Reed , W. , Palacios-Moreno , J. , Keefe , S. , Herritt , L. , Brooks , D. , Torres-Jardon , R. and Calderon-Garciduenas , L. In press . Urban air pollution produces up-regulation of myocardial inflammatory genes and dark chocolate provides cardioprotection . Exp. Toxicol. Pathol ,
   Google Scholar
• Vioque-Fernandez , A. , Alves de Almeida , E. and Lopez-Barea , J. 2009 . Assessment of Donana National Park contamination in Procambarus clarkii: Integration of conventional biomarkers and proteomic approaches . Sci. Total Environ , 407 : 1784 – 97 .
   PubMed Web of Science ®Google Scholar
• Waring , J. F. , Jolly , R. A. , Ciurlionis , R. , Lum , P. Y. , Praestgaard , J. T. , Morfitt , D. C. , Buratto , B. , Roberts , C. , Schadt , E. and Ulrich , R. G. 2001 . Clustering of hepatotoxins based on mechanism of toxicity using gene expression profiles . Toxicol. Appl. Pharmacol , 175 : 28 – 42 .
   PubMed Web of Science ®Google Scholar
• Watanabe , H. , Kobayashi , K. , Kato , Y. , Oda , S. , Abe , R. , Tatarazako , N. and Iguchi , T. 2008 . Transcriptome profiling in crustaceans as a tool for ecotoxicogenomics: Daphnia magna DNA microarray . Cell Biol. Toxicol , 24 : 641 – 47 .
   PubMed Web of Science ®Google Scholar
• Welch , J. S. , Escoubet-Lozach , L. , Sykes , D. B. , Liddiard , K. , Greaves , D. R. and Glass , C. K. 2002 . TH2 cytokines and allergic challenge induce Ym1 expression in macrophages by a STAT6-dependent mechanism . J. Biol. Chem , 277 : 42821 – 29 .
   PubMed Web of Science ®Google Scholar
• Williams , T. D. , Gensberg , K. , Minchin , S. D. and Chipman , J. K. 2003 . A DNA expression array to detect toxic stress response in European flounder (Platichthys flesus) . Aquat. Toxicol , 65 : 141 – 57 .
   PubMed Web of Science ®Google Scholar
• Zhou , Y. , Jiang , L. and Rui , L. 2009 . Identification of MUP1 as a regulator for glucose and lipid metabolism in mice . J. Biol. Chem , 284 : 11152 – 59 .
   PubMed Web of Science ®Google Scholar