Pollutant Particles Induce Arginase II in Human Bronchial Epithelial Cells

REFERENCES

• Abbey , D. E. , Petersen , F. , Mills , P. K. and Beeson , W. L. 1993 . Long-term ambient concentrations of total suspended particulates, ozone, and sulfur dioxide and respiratory symptoms in a nonsmoking population . Arch. Environ. Health , 48 : 33 – 46 .
   PubMed Web of Science ®Google Scholar
• Barksdale , A. R. , Bernard , A. C. , Maley , M. E. , Gellin , G. L. , Kearney , P. A. , Boulanger , B. R. , Tsuei , B. J. and Ochoa , J. B. 2004 . Regulation of arginase expression by T-helper II cytokines and isoproterenol . Surgery , 135 : 527 – 35 .
   PubMed Web of Science ®Google Scholar
• Becker , S. , Dailey , L. A. , Soukup , J. M. , Grambow , S. C. , Devlin , R. B. and Huang , Y. C. 2005a . Seasonal variations in air pollution particle-induced inflammatory mediator release and oxidative stress . Environ. Health Perpect. , 113 : 1032 – 38 .
   PubMed Web of Science ®Google Scholar
• Becker , S. , Mundandhara , S. , Devlin , R. B. and Madden , M. 2005b . Regulation of cytokine production in human alveolar macrophages and airway epithelial cells in response to ambient air pollution particles: Further mechanistic studies . Toxicol. Appl. Pharmacol. , 207 : 269 – 75 .
   PubMedGoogle Scholar
• Becker , S. , Soukup , J. M. , Sioutas , C. and Cassee , F. R. 2003 . Response of human alveolar macrophages to ultrafine, fine, and coarse urban air pollution particles . Exp. Lung Res. , 29 : 29 – 44 .
   PubMed Web of Science ®Google Scholar
• Benson , R. C. , Hardy , K. A. and Morris , C. R. 2011 . Arginase and arginine dysregulation in asthma . J. Allergy (Cairo) , 2011 : 736319
   PubMedGoogle Scholar
• Bergeron , C. , Boulet , L. P. , Page , N. , Laviolette , M. , Zimmermann , N. , Rothenberg , M. E. and Hamid , Q. 2007 . Influence of cigarette smoke on the arginine pathway in asthmatic airways: Increased expression of arginase I . J. Allergy Clin. Immunol. , 119 : 391 – 97 .
   PubMed Web of Science ®Google Scholar
• Blanchet , S. , Ramgolam , K. , Baulig , A. , Marano , F. and Baeza-Squiban , A. 2004 . Fine particulate matter induces amphiregulin secretion by bronchial epithelial cells . Am. J. Respir. Cell. Mol. Biol. , 30 : 421 – 27 .
   PubMed Web of Science ®Google Scholar
• Bronte , V. and Zanovello , P. 2005 . Regulation of immune responses by L-arginine metabolism . Nat. Rev. Immunol. , 5 : 641 – 54 .
   PubMed Web of Science ®Google Scholar
• Brunekreef , B. and Forsberg , B. 2005 . Epidemiological evidence of effects of coarse airborne particles on health . Eur. Respir. J. , 26 : 309 – 18 .
   PubMed Web of Science ®Google Scholar
• Bune , A. J. , Shergill , J. K. , Cammack , R. and Cook , H. T. 1995 . L-Arginine depletion by arginase reduces nitric oxide production in endotoxic shock: An electron paramagnetic resonance study . FEBS Lett. , 366 : 127 – 30 .
   PubMed Web of Science ®Google Scholar
• Cao , D. , Bromberg , P. A. and Samet , J. M. 2010 . Diesel particle-induced transcriptional expression of p21 involves activation of EGFR, Src, and Stat3 . Am. J. Respir. Cell. Mol. Biol. , 42 : 88 – 95 .
   PubMed Web of Science ®Google Scholar
• Cao , D. , Tal , T. L. , Graves , L. M. , Gilmour , I. , Linak , W. , Reed , W. , Bromberg , P. A. and Samet , J. M. 2007 . Diesel exhaust particulate-induced activation of Stat3 requires activities of EGFR and Src in airway epithelial cells . Am. J. Physiol. Lung Cell. Mol. Physiol. , 292 : L422 – 29 .
   PubMed Web of Science ®Google Scholar
• Chen , L. C. , Miller , P. D. , Amdur , M. O. and Gordon , T. 1992 . Airway hyperresponsiveness in guinea pigs exposed to acid-coated ultrafine particles . J. Toxicol. Environ. Health , 35 : 165 – 74 .
   PubMed Web of Science ®Google Scholar
• Corraliza , I. and Moncada , S. 2002 . Increased expression of arginase II in patients with different forms of arthritis. Implications of the regulation of nitric oxide . J. Rheumatol. , 29 : 2261 – 65 .
   PubMed Web of Science ®Google Scholar
• D'Amato , G. , Liccardi , G. , D'Amato , M. and Holgate , S. 2005 . Environmental risk factors and allergic bronchial asthma . Clin. Exp. Allergy , 35 : 1113 – 24 .
   PubMed Web of Science ®Google Scholar
• Das , P. , Lahiri , A. and Chakravortty , D. 2010 . Modulation of the arginase pathway in the context of microbial pathogenesis: A metabolic enzyme moonlighting as an immune modulator . PLoS Pathog. , 6 : e1000899
   PubMed Web of Science ®Google Scholar
• Dreher , K. , Jaskot , R. , Kodavanti , U. , Lehmann , J. , Winsett , D. and Costa , D. 1996 . Soluble transition metals mediate the acute pulmonary injury and airway hyperreactivity induced by residual oil fly ash particles . Chest. , 109 : 33S – 34S .
   PubMed Web of Science ®Google Scholar
• Ebtekar , M. 2006 . Air pollution induced asthma and alterations in cytokine patterns . Iran J. Allergy Asthma Immunol. , 5 : 47 – 56 .
   PubMedGoogle Scholar
• Erdely , A. , Kepka-Lenhart , D. , Clark , M. , Zeidler-Erdely , P. , Poljakovic , M. , Calhoun , W. J. and Morris , S. M., Jr . 2006 . Inhibition of phosphodiesterase 4 amplifies cytokine-dependent induction of arginase in macrophages . Am. J. Physiol. Lung Cell. Mol. Physiol. , 290 : L534 – 39 .
   PubMed Web of Science ®Google Scholar
• Gavett , S. H. and Koren , H. S. 2001 . The role of particulate matter in exacerbation of atopic asthma . Int. Arch. Allergy Immunol. , 124 : 109 – 12 .
   PubMed Web of Science ®Google Scholar
• Gavett , S. H. , Madison , S. L. , Dreher , K. L. , Winsett , D. W. , McGee , J. K. and Costa , D. L. 1997 . Metal and sulfate composition of residual oil fly ash determines airway hyperreactivity and lung injury in rats . Environ. Res. , 72 : 162 – 72 .
   PubMed Web of Science ®Google Scholar
• Ghio , A. J. , Kim , C. and Devlin , R. B. 2000 . Concentrated ambient air particles induce mild pulmonary inflammation in healthy human volunteers . Am. J. Respir. Crit. Care Med. , 162 : 981 – 88 .
   PubMed Web of Science ®Google Scholar
• Hamada , K. , Goldsmith , C. A. and Kobzik , L. 1999 . Increased airway hyperresponsiveness and inflammation in a juvenile mouse model of asthma exposed to air-pollutant aerosol . J. Toxicol. Environ. Health A , 58 : 129 – 43 .
   PubMed Web of Science ®Google Scholar
• Huang , Y. C. , Ghio , A. J. , Stonehuerner , J. , McGee , J. , Carter , J. D. , Grambow , S. C. and Devlin , R. B. 2003 . The role of soluble components in ambient fine particles-induced changes in human lungs and blood . Inhal. Toxicol. , 15 : 327 – 42 .
   PubMed Web of Science ®Google Scholar
• Huang , Y. C. , Karoly , E. D. , Dailey , L. A. , Schmitt , M. T. , Silbajoris , R. , Graff , D. W. and Devlin , R. B. 2011 . Comparison of gene expression profiles induced by coarse, fine, and ultrafine particulate matter . J. Toxicol. Environ. Health A , 74 : 296 – 312 .
   PubMed Web of Science ®Google Scholar
• Huang , Y. C. , Li , Z. , Hyseni , X. , Schmitt , M. , Devlin , R. B. , Karoly , E. D. and Soukup , J. M. 2008 . Identification of gene biomarkers for respiratory syncytial virus infection in a bronchial epithelial cell line . Genomic Med. , 2 : 113 – 25 .
   PubMedGoogle Scholar
• Huang , Y. C. , Wu , W. , Ghio , A. J. , Carter , J. D. , Silbajoris , R. , Devlin , R. B. and Samet , J. M. 2002 . Activation of EGF receptors mediates pulmonary vasoconstriction induced by residual oil fly ash . Exp. Lung Res. , 28 : 19 – 38 .
   PubMed Web of Science ®Google Scholar
• Huynh , N. N. and Chin-Dusting , J. 2006 . Amino acids, arginase and nitric oxide in vascular health . Clin. Exp. Pharmacol. Physiol. , 33 : 1 – 8 .
   PubMed Web of Science ®Google Scholar
• Iyer , R. , Jenkinson , C. P. , Vockley , J. G. , Kern , R. M. , Grody , W. W. and Cederbaum , S. 1998 . The human arginases and arginase deficiency . J. Inherit. Metab. Dis. , 21 : 86 – 100 .
   PubMed Web of Science ®Google Scholar
• Klasen , S. , Hammermann , R. , Fuhrmann , M. , Lindemann , D. , Beck , K. F. , Pfeilschifter , J. and Racke , K. 2001 . Glucocorticoids inhibit lipopolysaccharide-induced up-regulation of arginase in rat alveolar macrophages . Br. J. Pharmacol. , 132 : 1349 – 57 .
   PubMed Web of Science ®Google Scholar
• Lee , C. C. , Liao , J. W. and Kang , J. J. 2004 . Motorcycle exhaust particles induce airway inflammation and airway hyperresponsiveness in BALB/C mice . Toxicol. Sci. , 79 : 326 – 34 .
   PubMed Web of Science ®Google Scholar
• Lee , S. L. , Wong , W. H. and Lau , Y. L. 2006 . Association between air pollution and asthma admission among children in Hong Kong . Clin. Exp. Allergy , 36 : 1138 – 46 .
   PubMed Web of Science ®Google Scholar
• Li , H. , Romieu , I. , Sienra-Monge , J. J. , Ramirez-Aguilar , M. , Estela Del Rio-Navarro , B. , Kistner , E. O. , Gjessing , H. K. , Lara-Sanchez Idel , C. , Chiu , G. Y. and London , S. J. 2006 . Genetic polymorphisms in arginase I and II and childhood asthma and atopy . J. Allergy Clin. Immunol. , 117 : 119 – 26 .
   PubMed Web of Science ®Google Scholar
• Li , N. , Hao , M. , Phalen , R. F. , Hinds , W. C. and Nel , A. E. 2003 . Particulate air pollutants and asthma. A paradigm for the role of oxidative stress in PM-induced adverse health effects . Clin. Immunol. , 109 : 250 – 65 .
   PubMed Web of Science ®Google Scholar
• Maarsingh , H. , Leusink , J. , Bos , I. S. , Zaagsma , J. and Meurs , H. 2006 . Arginase strongly impairs neuronal nitric oxide-mediated airway smooth muscle relaxation in allergic asthma . Respir. Res. , 7 : 6
   PubMed Web of Science ®Google Scholar
• Maarsingh , H. , Zaagsma , J. and Meurs , H. 2009 . Arginase: A key enzyme in the pathophysiology of allergic asthma opening novel therapeutic perspectives . Br. J. Pharmacol. , 158 : 652 – 64 .
   PubMed Web of Science ®Google Scholar
• Matsumoto , G. , Nakagawa , N. K. , Vieira , R. P. , Mauad , T. , da Silva , L. F , de Andre , C. D. , Carvalho-Oliveira , R. , Saldiva , P. H. and Garcia , M. L. 2010 . The time course of vasoconstriction and endothelin receptor A expression in pulmonary arterioles of mice continuously exposed to ambient urban levels of air pollution . Environ. Res. , 110 : 237 – 43 .
   PubMed Web of Science ®Google Scholar
• Matthiesen , S. , Lindemann , D. , Warnken , M. , Juergens , U. R. and Racke , K. 2008 . Inhibition of NADPH oxidase by apocynin inhibits lipopolysaccharide (LPS) induced up-regulation of arginase in rat alveolar macrophages . Eur. J. Pharmacol. , 579 : 403 – 10 .
   PubMed Web of Science ®Google Scholar
• Milligan , P. J. , Brabin , B. J. , Kelly , Y. J. , Pearson , M. G. , Mahoney , G. , Dunne , E. , Heaf , D. and Reid , J. 1998 . Association of spatial distribution of childhood respiratory morbidity with environmental dust pollution . J. Toxicol. Environ. Health A , 55 : 169 – 84 .
   PubMed Web of Science ®Google Scholar
• Miyabara , Y. , Ichinose , T. , Takano , H. and Sagai , M. 1998 . Diesel exhaust inhalation enhances airway hyperresponsiveness in mice . Int. Arch. Allergy Immunol. , 116 : 124 – 31 .
   PubMed Web of Science ®Google Scholar
• Mori , M. and Gotoh , T. 2000 . Regulation of nitric oxide production by arginine metabolic enzymes . Biochem. Biophys. Res. Commun. , 275 : 715 – 19 .
   PubMed Web of Science ®Google Scholar
• Morris , C. R. , Poljakovic , M. , Lavrisha , L. , Machado , L. , Kuypers , F. A. and Morris , S. M., Jr . 2004 . Decreased arginine bioavailability and increased serum arginase activity in asthma . Am. J. Respir. Crit. Care Med. , 170 : 148 – 53 .
   PubMed Web of Science ®Google Scholar
• Morris , S. M., Jr . 2006 . Arginine: Beyond protein . Am. J. Clin. Nutr. , 83 : 508S – 512S .
   PubMed Web of Science ®Google Scholar
• Morris , S. M., Jr , Kepka-Lenhart , D. and Chen , L. C. 1998 . Differential regulation of arginases and inducible nitric oxide synthase in murine macrophage cells . Am. J. Physiol. , 275 : E740 – 47 .
   PubMed Web of Science ®Google Scholar
• Munder , M. 2009 . Arginase: An emerging key player in the mammalian immune system . Br. J. Pharmacol. , 158 : 638 – 51 .
   PubMed Web of Science ®Google Scholar
• Nelin , L. D. , Chicoine , L. G. , Reber , K. M. , English , B. K. , Young , T. L. and Liu , Y. 2005 . Cytokine-induced endothelial arginase expression is dependent on epidermal growth factor receptor . Am. J. Respir. Cell. Mol. Biol. , 33 : 394 – 401 .
   PubMed Web of Science ®Google Scholar
• North , M. L. , Amatullah , H. , Khanna , N. , Urch , B. , Grasemann , H. , Silverman , F. and Scott , J. A. 2011 . Augmentation of arginase 1 expression by exposure to air pollution exacerbates the airways hyperresponsiveness in murine models of asthma . Respir. Res. , 12 : 19
   PubMed Web of Science ®Google Scholar
• North , M. L. , Khanna , N. , Marsden , P. A. , Grasemann , H. and Scott , J. A. 2009 . Functionally important role for arginase 1 in the airway hyperresponsiveness of asthma . Am. J. Physiol. Lung Cell. Mol. Physiol. , 296 : L911 – 20 .
   PubMed Web of Science ®Google Scholar
• Nurkiewicz , T. R. , Porter , D. W. , Hubbs , A. F. , Stone , S. , Moseley , A. M. , Cumpston , J. L. , Goodwill , A. G. , Frisbee , S. J. , Perrotta , P. L. , Brock , R. W. , Frisbee , J. C. , Boegehold , M. A. , Frazer , D. G. , Chen , B. T. and Castranova , V. 2011 . Pulmonary particulate matter and systemic microvascular dysfunction . Res. Rep. Health Eff. Inst. , : 3 – 48 .
   PubMedGoogle Scholar
• Oosterlee , A. , Drijver , M. , Lebret , E. and Brunekreef , B. 1996 . Chronic respiratory symptoms in children and adults living along streets with high traffic density . Occup. Environ. Med. , 53 : 241 – 47 .
   PubMed Web of Science ®Google Scholar
• Ozaki , M. , Gotoh , T. , Nagasaki , A. , Miyanaka , K. , Takeya , M. , Fujiyama , S. , Tomita , K. and Mori , M. 1999 . Expression of arginase II and related enzymes in the rat small intestine and kidney . J. Biochem. , 125 : 586 – 93 .
   PubMed Web of Science ®Google Scholar
• Penttinen , P. , Vallius , M. , Tiittanen , P. , Ruuskanen , J. and Pekkanen , J. 2006 . Source-specific fine particles in urban air and respiratory function among adult asthmatics . Inhal. Toxicol. , 18 : 191 – 98 .
   PubMed Web of Science ®Google Scholar
• Pope , C. A. , 3rd, Dockery , D. W. , Spengler , J. D. and Raizenne , M. E. 1991 . Respiratory health and PM10 pollution. A daily time series analysis . Am. Rev. Respir. Dis. , 144 : 668 – 74 .
   PubMed Web of Science ®Google Scholar
• Que , L. G. , George , S. E. , Gotoh , T. , Mori , M. and Huang , Y. C. 2002 . Effects of arginase isoforms on NO Production by nNOS . Nitric Oxide , 6 : 1 – 8 .
   PubMed Web of Science ®Google Scholar
• Que , L. G. , Kantrow , S. P. , Jenkinson , C. P. , Piantadosi , C. A. and Huang , Y. C. 1998 . Induction of arginase isoforms in the lung during hyperoxia . Am. J. Physiol. , 275 : L96 – 102 .
   PubMed Web of Science ®Google Scholar
• Rumelhard , M. , Ramgolam , K. , Hamel , R. , Marano , F. and Baeza-Squiban , A. 2007 . Expression and role of EGFR ligands induced in airway cells by PM2.5 and its components . Eur. Respir. J. , 30 : 1064 – 73 .
   PubMed Web of Science ®Google Scholar
• Salimuddin , Nagasaki , A. , Gotoh , T. , Isobe , H. and Mori , M. 1999 . Regulation of the genes for arginase isoforms and related enzymes in mouse macrophages by lipopolysaccharide . Am. J. Physiol. , 277 : E110 – 17 .
   PubMed Web of Science ®Google Scholar
• Samet , J. M. , Dewar , B. J. , Wu , W. and Graves , L. M. 2003 . Mechanisms of Zn(2+)-induced signal initiation through the epidermal growth factor receptor . Toxicol. Appl. Pharmacol. , 191 : 86 – 93 .
   PubMed Web of Science ®Google Scholar
• Soukup , J. M. and Becker , S. 2001 . Human alveolar macrophage responses to air pollution particulates are associated with insoluble components of coarse material, including particulate endotoxin . Toxicol. Appl. Pharmacol. , 171 : 20 – 26 .
   PubMed Web of Science ®Google Scholar
• Steenhof , M. , Gosens , I. , Strak , M. , Godri , K. J. , Hoek , G. , Cassee , F. R. , Mudway , I. S. , Kelly , F. J. , Harrison , R. M. , Lebret , E. , Brunekreef , B. , Janssen , N. A. and Pieters , R. H. 2011 . In vitro toxicity of particulate matter (PM) collected at different sites in the Netherlands is associated with PM composition, size fraction and oxidative potential—The RAPTES project . Part. Fibre. Toxicol. , 8 : 26
   PubMed Web of Science ®Google Scholar
• Tal , T. L. , Bromberg , P. A. , Kim , Y. and Samet , J. M. 2008 . Epidermal growth factor receptor activation by diesel particles is mediated by tyrosine phosphatase inhibition . Toxicol. Appl. Pharmacol. , 233 : 382 – 88 .
   PubMed Web of Science ®Google Scholar
• Tal , T. L. , Graves , L. M. , Silbajoris , R. , Bromberg , P. A. , Wu , W. and Samet , J. M. 2006 . Inhibition of protein tyrosine phosphatase activity mediates epidermal growth factor receptor signaling in human airway epithelial cells exposed to Zn2+ . Toxicol. Appl. Pharmacol. , 214 : 16 – 23 .
   PubMed Web of Science ®Google Scholar
• Tewari , A. K. , Popova-Butler , A. , El-Mahdy , M. A. and Zweier , J. L. 2011 . Identification of differentially expressed proteins in blood plasma of control and cigarette smoke-exposed mice by 2-D DIGE/MS . Proteomics , 11 : 2051 – 62 .
   PubMed Web of Science ®Google Scholar
• Toby , I. T. , Chicoine , L. G. , Cui , H. , Chen , B. and Nelin , L. D. 2010 . Hypoxia-induced proliferation of human pulmonary microvascular endothelial cells depends on epidermal growth factor receptor tyrosine kinase activation . Am. J. Physiol. Lung Cell Mol. Physiol. , 298 : L600 – 6 .
   PubMed Web of Science ®Google Scholar
• Trasande , L. and Thurston , G. D. 2005 . The role of air pollution in asthma and other pediatric morbidities . J. Allergy Clin. Immunol. , 115 : 689 – 99 .
   PubMed Web of Science ®Google Scholar
• Vigotti , M. A. , Chiaverini , F. , Biagiola , P. and Rossi , G. 2007 . Urban air pollution and emergency visits for respiratory complaints in Pisa, Italy . J. Toxicol. Environ. Health A. , 70 : 266 – 69 .
   PubMed Web of Science ®Google Scholar
• von Klot , S. , Wolke , G. , Tuch , T. , Heinrich , J. , Dockery , D. W. , Schwartz , J. , Kreyling , W. G. , Wichmann , H. E. and Peters , A. 2002 . Increased asthma medication use in association with ambient fine and ultrafine particles . Eur. Respir. J. , 20 : 691 – 702 .
   PubMed Web of Science ®Google Scholar
• Vonk , J. M. , Postma , D. S. , Maarsingh , H. , Bruinenberg , M. , Koppelman , G. H. and Meurs , H. 2010 . Arginase 1 and arginase 2 variations associate with asthma, asthma severity and beta2 agonist and steroid response . Pharmacogenet Genomics , 20 : 179 – 86 .
   PubMed Web of Science ®Google Scholar
• Walters , D. M. , Breysse , P. N. and Wills-Karp , M. 2001 . Ambient urban Baltimore particulate-induced airway hyperresponsiveness and inflammation in mice . Am. J. Respir. Crit. Care Med. , 164 : 1438 – 43 .
   PubMed Web of Science ®Google Scholar
• Weiland , S. K. , Mundt , K. A. , Ruckmann , A. and Keil , U. 1994 . Self-reported wheezing and allergic rhinitis in children and traffic density on street of residence . Ann. Epidemiol. , 4 : 243 – 247 .
   PubMedGoogle Scholar
• Wu , G. and Morris , S. M., Jr . 1998 . Arginine metabolism: Nitric oxide and beyond . Biochem. J. , 336 : 1 – 17 .
   PubMed Web of Science ®Google Scholar
• Wu , W. , Samet , J. M. , Ghio , A. J. and Devlin , R. B. 2001 . Activation of the EGF receptor signaling pathway in airway epithelial cells exposed to Utah Valley PM . Am. J. Physiol. Lung Cell Mol. Physiol. , 281 : L483 – 89 .
   PubMed Web of Science ®Google Scholar
• Yang , C. Y. , Chen , Y. S. , Yang , C. H. and Ho , S. C. 2004 . Relationship between ambient air pollution and hospital admissions for cardiovascular diseases in Kaohsiung, Taiwan . J. Toxicol. Environ. Health A. , 67 : 483 – 93 .
   PubMed Web of Science ®Google Scholar
• Zimmermann , N. , King , N. E. , Laporte , J. , Yang , M. , Mishra , A. , Pope , S. M. , Muntel , E. E. , Witte , D. P. , Pegg , A. A. , Foster , P. S. , Hamid , Q. and Rothenberg , M. E. 2003 . Dissection of experimental asthma with DNA microarray analysis identifies arginase in asthma pathogenesis . J. Clin. Invest. , 111 : 1863 – 74 .
   PubMed Web of Science ®Google Scholar
• Zimmermann , N. and Rothenberg , M. E. 2006 . The arginine-arginase balance in asthma and lung inflammation . Eur. J. Pharmacol. , 533 : 253 – 62 .
   PubMed Web of Science ®Google Scholar