Can Standard Genotoxicity Tests be Applied to Nanoparticles?

REFERENCES

• Collins , A. R. 2004 . The comet assay for DNA damage and repair: Principles, applications, and limitations . Mol. Biotechnol. , 26 : 249 – 61 .
   PubMed Web of Science ®Google Scholar
• EFSA Scientific Committee . 2011 . Guidance on the risk assessment of the application of nanoscience and nanotechnologies in the food and feed chain . EFSA J. , 9 : 2140 – 76 .
   Google Scholar
• Damoiseaux , R. , George , S. , Li , M. , Pokhrel , S. , Ji , Z. , France , B. , Xia , T. , Suarez , E. , Rallo , R. , Mädler , L. , Cohen , Y. , Hoek , E. M. and Nel , A. 2011 . No time to lose—High throughput screening to assess nanomaterial safety . Nanoscale , 3 : 1345 – 60 .
   PubMed Web of Science ®Google Scholar
• Fenech , M. 1997 . The advantages and disadvantages of the cytokinesis-block micronucleus method . Mutat. Res. , 392 : 11 – 18 .
   PubMed Web of Science ®Google Scholar
• Fenech , M. 2000 . The in vitro micronucleus technique . Mutat. Res. , 455 : 81 – 95 .
   PubMed Web of Science ®Google Scholar
• Fenech , M. , Chang , W.P. , Kirsch-Volders , M. , Holland , N. , Bonassi , S. and Zeiger , E. 2003 . HUMN project: Detailed description of the scoring criteria for the cytokinesis-block micronucleus assay using isolated human lymphocyte cultures . Mutat. Res. , 534 : 65 – 75 .
   PubMed Web of Science ®Google Scholar
• Karlsson , H. L. 2010 . The comet assay in nanotoxicology research . Anal. Bioanal. Chem. , 398 : 651 – 66 .
   PubMed Web of Science ®Google Scholar
• Kroll , A. , Pillukat , M. H. , Hahn , D. and Schnekenburger , J. 2009 . Current in vitro methods in nanoparticle risk assessment: Limitations and challenges . Eur. J. Pharm. Biopharm. , 72 : 370 – 77 .
   PubMed Web of Science ®Google Scholar
• Magdolenova , Z , Bilanicova , D , Pojana , G , Fjellsbø , LM , Hudecova , A , Hasplova , K , Marcomini , A and Dusinska , M. 2012 . Impact of agglomeration and different dispersions of titanium dioxide nanoparticles on the human related in vitro cytotoxicity and genotoxicity . J. Environ. Monit , 14 : 455 – 64 .
   PubMed Web of Science ®Google Scholar
• Maynard , A. D. , Warheit , D. B. and Philbert , M. A. 2011 . The new toxicology of sophisticated materials: nanotoxicology and beyond . Toxicol. Sci. , 120 ( suppl. 1 ) : S109 – 29 .
   PubMed Web of Science ®Google Scholar
• Oberdörster , G. , Maynard , A. , Donaldson , K. , Castranova , V. , Fitzpatrick , J. , Ausman , K. , Carter , J. , Karn , B. , Kreyling , W. , Lai , D. , Olin , S. , Monteiro-Riviere , N. , Warheit , D. and Yang , H. 2005 . ILSI Research Foundation/Risk Science Institute Nanomaterial Toxicity Screening Working Group. Principles for characterizing the potential human health effects from exposure to nanomaterials: Elements of a screening strategy . Part. Fibre Toxicol. , 2 : 8
   PubMed Web of Science ®Google Scholar
• Scientific Committee on Emerging and Newly-Identified Health Risks . 2009 . Health effects of exposure to EMF , Brussels , , Belgium : European Commission .
   Google Scholar
• Stone , V. , Johnston , H. and Schins , R. P. 2009 . Development of in vitro systems for nanotoxicology: Methodological considerations . Crit. Rev. Toxicol. , 39 : 613 – 26 .
   PubMed Web of Science ®Google Scholar
• Zhao , J. and Castranova , V. 2011 . Toxicology of nanomaterials used in medicince . J. Toxicol. Environ. Health B , 14 : 593 – 632 .
   PubMed Web of Science ®Google Scholar