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Original Articles

Effects of Diuron on Male Rat Reproductive Organs: A Developmental and Postnatal Study

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Pages 1059-1069 | Published online: 01 Aug 2012

REFERENCES

  • Abass , K. , Reponen , P. , Turpeinen , M. , Jalonen , J. and Pelkonen , O. 2007 . Characterization of diuron N-demethylation by mammalian hepatic microsomes and cDNA-expressed human cytochrome P450 enzymes . Drug Metab. Dispos. , 35 : 1634 – 41 .
  • Agrawal , R. C. and Kumar , S. 1999 . Hepato-toxic effect of diuron in adult rats . Indian J. Exp. Biol. , 37 : 503 – 4 .
  • Agrawal , R. C. and Melhrota , N. K. 1997 . Effect of diuron on germ cells of mice . Indian J. Exp. Biol. , 35 : 1256 – 57 .
  • Ashby , J. , Tinwell , H. , Lefevre , P. A. , Joiner , R. and Haseman , J. 2003 . The effect on sperm production in adult Sprague-Dawley rats exposed by gavage to bisphenol A between postnatal days 91–97 . Toxicol. Sci. , 74 : 129 – 38 .
  • Bauer , E. R. , Meyer , H. H. , Stahlschmidt-Allner , P. and Sauerwein , H. 1998 . Application of an androgen receptor assay for the characterization of the androgenic or antiandrogenic of activity of various phenylurea herbicides and their derivatives . Analyst , 123 : 2485 – 87 .
  • Bhatt , R. V. 2000 . Environmental influence on reproductive health . Int. J. Gynaecol. Obstet. , 70 : 69 – 75 .
  • Choi , S. M. , Yoo , S. D. and Lee , B. M. 2004 . Toxicological characteristics of endocrine-disrupting chemicals: Developmental toxicity, carcinogenicity and mutagenicity . J. Toxicol. Environ. Health B , 7 : 1 – 24 .
  • Clegg , E. D. , Perreault , D. and Klinefelter , G. R. 2001 . “ Assessment of male reproductive toxicity ” . In Principles and methods of toxicology , Edited by: Hayes , A. W. 1263 – 1300 . Philadelphia , PA : Taylor & Francis .
  • Collins , T. F. , Sprando , R. L. , Shackelford , M. E. , Hansen , D. K. and Welsh , J. J. 1999 . Food and drug administration proposed testing guidelines for reproduction studies . Regul. Toxicol. Pharmacol. , 30 : 29 – 38 .
  • Diamanti-Kandarakis , E. , Bourguignon , J. P. , Giudice , L. C. , Hauser , R. , Prins , G. S. , Soto , A. M. , Zoeller , R. T. and Gore , A. C. 2009 . Endocrine-disrupting chemicals: An Endocrine Society scientific statement . Endocr. Rev. , 30 : 293 – 342 .
  • Domingues , A. , Barbisan , L. F. , Martins , P. R. and Spinardi-Barbisan , A. L. 2011 . Diuron exposure induces systemic and organ-specific toxicity following acute and sub-chronic exposure in male Wistar rats . Environ. Toxicol. Pharmacol. , 31 : 387 – 96 .
  • Domingues , A. , Grassi , T. F. , Spinardi-Barbisan , A. L. T. and Barbisan , L. F. 2012 . Developmental exposure to diuron causes splenotoxicity in male Sprague-Dawley rat pups . J. Environ. Sci. Health B , 47 : 420 – 26 .
  • Favareto , A. P. , Fernandez , C. D. , da Silva , D. A. , Anselmo-Franci , J. A. and Kempinas , W. G. 2011 . Persistent impairment of testicular histology and sperm motility in adult rats treated with cisplatin at peri-puberty . Basic Clin. Pharmacol. Toxicol. , 109 : 85 – 96 .
  • Fernandes , G. S. A. , Arena , A. C. , Fernandez , C. D. , Mercadante , A. , Barbisan , L. F. and Kempinas , W. G. 2007 . Reproductive effects in male rats exposed to diuron . Reprod. Toxicol. , 23 : 106 – 12 .
  • Field , J. A. , Reed , R. L. , Sawyer , T. E. , Griffith , S. M. and Wigington , P. J. 2003 . Diuron occurrence and distribution in soil and surface and ground ware associated with grass seed production . J. Environ. Qual. , 32 : 171 – 79 .
  • Filler , R. 1993 . “ Methods for evaluation of rats epididymal sperm morphology ” . In Male reproductive toxicology , Edited by: Chapin , R. E. and Heindel , J. H. 334 – 43 . San Diego , CA : Academic Press .
  • Foster , W. G. , Neal , M. S. , Han , M.-S. and Dominguez , M. M. 2008 . Environmental contaminants and human infertility: Hypothesis or cause for concern . J. Toxicol. Environ. Health B , 11 : 162 – 76 .
  • França , L. R. , Avelar , G. F. and Almeida , F. F. L. 2005 . Spermatogenesis and transit through the epididymis in mammals with emphasis on pigs . Theriogenology , 63 : 300 – 18 .
  • Giacomazzi , S. and Cochet , N. 2004 . Environmental impact of diuron transformation: A review . Chemosphere , 56 : 1021 – 32 .
  • Grassi , T. F. , Guerra , M. T. , Perobelli , J. E. , de Toledo , F. C. , da Silva , D. S. , De Grava Kempinas , W. and Barbisan , L. F. 2011 . Assessment of female reproductive endpoints in Sprague-Dawley rats developmentally exposed to diuron: Potential ovary toxicity . Birth Defects Res. B. Dev. Reprod. Toxicol. , 92 : 478 – 86 .
  • Iyer , P. 2002 . Evidence on the developmental and reproductive toxicity of diuron draft. Reproductive and cancer hazard assessment section , 43 Sacramento : Office of Environmental Health Hazard Assessment (OEHHA), California Environmental Protection Agency .
  • Khera , K. S. , Whalen , C. , Trivett , G. and Angers , G. 1979 . Teratogenicity studies on pesticidal formulations of dimethoate, diuron and lindane in rats . Bull. Environ. Contam. Toxicol. , 22 : 522 – 29 .
  • Klinefelter , G. R. 2002 . “ Actions of toxicants on the structure and function of the epididymis ” . In The epididymis—From molecules to clinical practice , Edited by: Robaire , B. and Hinton , B. T. 353 – 69 . New York , NY : Kluwer Academic/Plenum .
  • Lo , S. , King , I. , Alléra , A. and Klingmüller , D. 2007 . Effects of various pesticides on human 5alpha-reductase activity in prostate and LNCaP cells . Toxicol. In Vitro , 21 : 502 – 8 .
  • Mann , T. 1974 . Secretory function of the prostate, seminal vesicle and other male accessory organs of reproduction . J. Reprod. Fertil. , 37 : 179 – 88 .
  • Makris , S. L. , Kim , J. H. , Ellis , A. , Faber , W. , Harrouk , W. , Lewis , J. M. , Paule , M. G. , Seed , J. , Tassinari , M. and Tyl , R. 2011 . Current and future needs for developmental toxicity testing . Birth Defects Res. B Dev. Reprod. Toxicol. , 92 : 384 – 94 .
  • McIntyre , B. S. , Barlow , N. J. and Foster , P. M. 2002 . Male rats exposed to linuron in utero exhibit permanent changes in anogenital distance, nipple retention, and epididymal malformations that result in subsequent testicular atrophy . Toxicol. Sci. , 65 : 62 – 70 .
  • Nassr , A. C. , Arena , A. C. , Toledo , F. C. , Bissacot , D. Z. , Fernandez , C. D. , Spinardi-Barbisan , A. L. , Pires , P. W. and Kempinas , W. G. 2010 . Effects of gestational and lactational fenvalerate exposure on immune and reproductive systems of male rats . J. Toxicol. Environ. Health A , 73 : 952 – 64 .
  • OEHHA. 2001. Office of Environmental Health Hazard Assessment—OEHHA. Proposition 65 – notices of Intent to List. California Sacramento (CA). http://www.oehha.org/Prop65/CRNR_notices/admin_listing/intent_to_list/referenced_docs/pkg11b2.html (http://www.oehha.org/Prop65/CRNR_notices/admin_listing/intent_to_list/referenced_docs/pkg11b2.html)
  • Okamura , H. , Aoyama , I. , Ono , Y. and Nishida , T. 2003 . Antifouling herbicides in the coastal waters of western Japan . Mar. Pollut. Bull. , 47 : 59 – 67 .
  • Perobelli , J. E. , Martinez , M. F. , Franchi , C. A. S. , Fernandez , C. D. , Camargo , J. L. and Kempinas , W. G. 2010 . Decreased sperm motility in rats orally exposed to single or mixed pesticides . J. Toxicol. Environ. Health A , 73 : 991 – 1002 .
  • Phillips , K. P. and Tanphaichitr , N. 2008 . Human exposure to endocrine disrupters and semen quality . J. Toxicol. Environ. Health B , 11 : 188 – 220 .
  • Robb , G. W. , Amman , R. P. and Killian , G. J. 1978 . Daily sperm production and epididymal sperm reserves of puberal and adult rats . J. Reprod. Fertil. , 54 : 103 – 7 .
  • Roy , D. , Palangat , M. , Chen , C.-W. , Thomas , R. D. , Colerangle , J. , Atkinson , A. and Yan , Z.-J. 1998 . Biochemical and molecular changes at the cellular level in reponse to exposure to environmental estrogen-like chemicals . J. Toxicol. Environ. Health , 50 : 1 – 29 .
  • Scarano , W. R. , Toledo , F. C. , Guerra , M. T. , Pinheiro , P. F. , Domeniconi , R. F. , Felisbino , S. L. , Campos , S. G. , Taboga , S. R. and Kempinas , W. G. 2010 . Functional and morphological reproductive aspects in male rats exposed to di-n-butyl phthalate (DBP) in utero and during lactation . J. Toxicol. Environ. Health A , 73 : 972 – 84 .
  • Seed , J. , Chapi , R. E. , Clegg , E. D. , Dostal , L. A. , Foote , R. E. , Hurtt , M. E. , Klinefelter , G. R. , Makris , S. L. , Perreault , S. D. , Schrader , S. , Seyler , D. , Sprando , R. , Treinen , K. A. , Veeramachaneni , D. N. and Wise , L. D. 1996 . Methods for assessing sperm motility, morphology, and counts in the rat, rabbit, and dog: A consensus report . Reprod. Toxicol. , 10 : 237 – 44 .
  • Turner , K. J. , McIntyre , B. S. , Phillips , S. L. , Barlow , N. J. , Bowman , C. J. and Foster , P. M. 2003 . Altered gene expression during rat Wolffian duct development in response to in utero exposure to the antiandrogen linuron . Toxicol. Sci. , 74 : 114 – 28 .
  • U.S. Environmental Protection Agency . 2003 . Reregistration eligibility decision for diuon. List A. Case 0046 , Vol. 22 , Washington , DC : Office of Prevetion, Pesticides and Toxic Substances, U.S. EPA .
  • U. S. Environmental Protection Agency (USEPA) . 2004 . Chemicals Evaluated for Carcinogenic Potential , Washington , D.C. : Office of Pesticide Programs, HealthEffects Division. Science Information Management Branch . Science Information Management Branch
  • Van Boven , M. , Laruelle , L. and Daenens , P. 1990 . HPLC analysis of diuron and metabolites in blood and urine . J. Anal. Toxicol. , 14 : 231 – 34 .
  • Vinggaard , A. M. , Breinholt , V. and Larsen , J. C. 1999 . Screening of selected pesticides for oestrogen receptor activation in vitro . Food Addit. Contam. , 16 : 533 – 42 .
  • Vinggaard , A. M. , Hnida , C. , Breinholt , V. and Larsen , J. C. 2000 . Screening of selected pesticides for inhibition of CYP19 aromatase activity in vitro . Toxicol. In Vitro , 14 : 227 – 34 .
  • Wittke , K. , Hajimiragha , H. , Dunemann , L. and Begerow , J. 2001 . Determination of dichloroanilines in human urine by GC-MS, GC-MS-MS, and GC-ECD as markers of low-level pesticide exposure . J. Chromatogr. B. Biomed. Sci. Appl. , 755 : 215 – 28 .
  • Wolf , C. J. , LeBlanc , G. A. , Ostby , J. S. and Gray , L. E. 2000 . Characterization of the period of sensitivity of fetal male sexual development to vinclozolin . Toxicol. Sci. , 55 : 152 – 61 .
  • Zenick , H. , Clegg , E. D. , Perreault , S. D. , Klinefelter , G. R. and Gray , L. E. 1994 . “ Assessment of male reproductive toxicity: A risk assessment approach ” . In Principles and methods of toxicology , 3rd , Edited by: Hayes , A. W. 937 – 88 . New York , NY : Raven .

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