Sodium Copper Chlorophyllin (SCC) Induces Genetic Damage in Postmeiotic and Somatic Wing Cells of Drosophila melanogaster

REFERENCES

• Cruces , M. P. , Pimentel , E. and Zimmering , S. 2003 . Evidence suggesting that chlorophyllin (CHLN) may act as an inhibitor or a promoter of genetic damage induced by chromium (VI) oxide (CrO3) in somatic cells of Drosophila. . Mutat. Res , 536 : 139 – 144 .
   PubMed Web of Science ®Google Scholar
• Cruces , M. P. , Pimentel , E. and Zimmering , S. 2009 . Evidence that low concentrations of chlorophyllin (CHLN) increase the genetic damage induced by gamma rays in somatic cells of Drosophila. . Mutat. Res , 679 : 84 – 86 .
   PubMed Web of Science ®Google Scholar
• Egner , P. A. , Wang , J. B. , Zhu , Y. R. , Zhang , B.C. , Wu , Y. , Zhang , Q. N. , Qian , G. S. , Kuang , S. Y. , Gange , S. J. , Jacobson , L. P. , Helzlsouer , K. J. , Bailey , G. S. , Groopman , J. D. and Kensler , T. W. 2001 . Chlorophyllin intervention reduces aflatoxin–DNA adducts in individuals at high risk for liver cancer . Proc. Natl. Acad. Sci. USA , 98 : 14601 – 14606 .
   PubMed Web of Science ®Google Scholar
• Ferguson , L.R. and Philpott , M. 2008 . Nutrition and mutagenesis . Annu. Rev. Nutr , 28 : 313 – 329 .
   PubMed Web of Science ®Google Scholar
• Frei , F. and Würgler , F. E. 1988 . Statistical methods to decide whether mutagenicity test data from Drosophila assays indicate a positive, negative, or inconclusive result . Mutat. Res , 203 : 297 – 308 .
   PubMed Web of Science ®Google Scholar
• Frenzilli , G. , Bosco , E. and Barale , R. 2000 . Validation of single cell gel assay in human leukocytes with 18 reference compounds . Mutat. Res , 468 : 93 – 108 .
   PubMed Web of Science ®Google Scholar
• Graf , U. , Würgler , F. E. , Katz , A. J. , Frei , H. , Juon , H. , Hall , C. B. and Kale , P. G. 1984 . Somatic mutation and recombination test in Drosophila melanogaster. . Environ. Mutagen , 6 : 153 – 188 .
   PubMedGoogle Scholar
• Lee , W. R. , Abrahamson , S. , Valencia , R. , von Halle , E. S. , Würgler , F. E. and Zimmering , S. 1983 . “ The sex-linked recessive lethal test for mutagenesis in Drosophila melanogaster: A report of the U.S. environmental protection agency Gene-Tox program ” . In Mutat. Res Vol. 123 , 183 – 279 .
   Google Scholar
• Lindsley , D. and Zimm , G. 1992 . The genome of Drosophila melanogaster , San Diego , CA : Academic Press .
   Google Scholar
• Nelson , R. L. 1992 . Chlorophyllin, an antimutagen, acts as a tumor promoter in the rat-dimethylhydrazine colon carcinogenesis model . Anticancer Res , 12 : 737 – 739 .
   PubMed Web of Science ®Google Scholar
• Odin , A. P. 1997 . Antimutagenicity of the porphyrin and non-enzyme porphyrin-containing proteins . Mutat. Res , 387 : 55 – 68 .
   PubMed Web of Science ®Google Scholar
• Olvera , O. , Zimmering , S. , Arceo , C. and Cruces , M. 1993 . The protective effects of chlorophyllin in treatment with chromium (VI) oxide in somatic cells of Drosophila. . Mutat. Res , 301 : 201 – 204 .
   PubMed Web of Science ®Google Scholar
• Owen , D. B. 1962 . Handbook of statistical tables , London , UK : Addison-Wesley .
   Google Scholar
• Pimentel , E. , Cruces , M. P. and Zimmering , S. 1999 . On the persistence of the radioprotective effect of chlorophyllin (CHLN) in somatic cells of Drosophila. . Mutat. Res , 446 : 189 – 192 .
   PubMed Web of Science ®Google Scholar
• Pimentel , E. , Cruces , M. P. and Zimmering , S. 2000 . Evidence that chlorophyllin (CHLN) may behave as an inhibitor or a promoter of radiation-induced genetic damage in somatic cells of Drosophila. . Mutat. Res , 472 : 71 – 74 .
   PubMed Web of Science ®Google Scholar
• Pimentel , E. , Cruces , M. P. and Zimmering , S. 2011 . A study of the inhibition/promotion effects of sodium–copper chlorophyllin (SCC)-mediated mutagenesis in somatic cells of Drosophila. . Mutat. Res , 722 : 52 – 55 .
   PubMed Web of Science ®Google Scholar
• Pimentel , E. , Cruces , M. P. and Zimmering , S. 2013 . A further study of the role of copper in regard to the antimutagenic action of sodium copper chlorophyllin (SCC) in somatic cells of Drosophila melanogaster. . Biomarker Ins , 8 : 29 – 33 .
   PubMedGoogle Scholar
• Rigonato , J. , Mantovani , M. S. and Jordão , B. Q. 2004 . Mechanism of action of chlorophyllin against mitomycin-C mutagenicity in Allium cepa. . Cytologia , 69 : 459 – 465 .
   Google Scholar
• Romert , L.M. , Curvall , M. and Jenssen , D. 1992 . Chlorophyllin is both a positive and negative modifier of mutagenicity . Mutagenesis , 7 : 349 – 355 .
   PubMed Web of Science ®Google Scholar
• Sarkar , D. , Sharma , A. and Talukder , G. 1996 . Chlorophyll and chromosome breakage . Mutat Res , 360 : 87 – 91 .
   Google Scholar
• Vesenick , D. C. , Aparecida de Paula , N. , Megumi , A. and Mantovani , M. S. 2012 . Evaluation of the effects of chlorophyllin on apoptosis induction, inhibition of cellular proliferation and mRNA expression of CASP8, CASP9, APC and β-catenin . Curr. Res. J. Biol. Sci , 4 : 315 – 322 .
   Google Scholar
• Waters , M. D. , Stack , H. F. , Jackson , M. A. , Brockman , H. E. and De Flora , S. 1996 . Activity profiles of antimutagens: In vitro and in vivo data . Mutat. Res , 350 : 109 – 129 .
   PubMed Web of Science ®Google Scholar
• Xu , M. , Orner , G. A. , Bailey , G. S. , Stoner , G. D. , Horio , D. T. and Dashwood , R. H. 2001 . Post-initiation effects of chlorophyllin and indole-3-carbinol in rats given 1,2-dimethylhydrazine or 2-amino-3-methyl- imidazo . Carcinogenesis , 22 : 309 – 314 .
   PubMed Web of Science ®Google Scholar
• Zimmering , S. , Olvera , O. , Hernández , M. E. , Cruces , M. P. , Arceo , C. and Pimentel , E. 1990 . Evidence for radioprotective effects of chlorophyllin in Drosophila. . Mutat. Res , 245 : 47 – 49 .
   PubMed Web of Science ®Google Scholar
• Zimmering , S. and Thompson , E. 1984 . Comparison of rates of sex-linked recessive lethals induced by ethylnitrosourea (ENU) in postmeiotic cells of the male and oogonia of the female . Drosophila. Environ. Mutagen , 6 : 617 – 619 .
   PubMedGoogle Scholar