BDE-154 Induces Mitochondrial Permeability Transition and Impairs Mitochondrial Bioenergetics

REFERENCES

• Adam-Vizi , V. 2005 . Production of reactive oxygen species in brain mitochondria: Contribution by electron transport chain and non-electron transport chain sources . Antioxid. Redox. Signal , 7 : 1140 – 1149 .
   PubMed Web of Science ®Google Scholar
• Agency for Toxic Substances and Disease Registry. 2004. Toxicological profile for polybrominated biphenyls and polybrominated diphenyls and polybrominated diphenyls ethers. Atlanta, GA: U.S. Department of Health and Human Services, Public Health Service, Agency for Toxic Substances and Disease Registry http://www.atsdr.cdc.gov/ToxProfiles/tp68.pdf (http://www.atsdr.cdc.gov/ToxProfiles/tp68.pdf) (Accessed: 19 April 2012 ).
   Google Scholar
• Akerman , K. E. O. and Wikstrom , M. K. F. 1976 . Safranine as a probe of the mitochondrial membrane potential . FEBS Lett , 68 : 191 – 197 .
   PubMed Web of Science ®Google Scholar
• Alaee , M. , Arias , P. , Sjodin , A. and Bergman , A. 2003 . An overview of commercially used brominated flame retardants, their applications, their use patterns in different countries/regions and possible modes of release . Environ. Int , 29 : 683 – 689 .
   PubMed Web of Science ®Google Scholar
• Bernardi , P. and Rasola , A. 2007 . Calcium and cell death: The mitochondrial connection . Subcell. Biochem , 45 : 481 – 506 .
   PubMedGoogle Scholar
• Cain , K. and Skilleter , D. N. 1987 . “ Preparation and use of mitochondria in toxicological research ” . In Biochemical toxicology: A practical approach , Edited by: Snell , K. and Mullock , B. 217 – 254 . Oxford , UK : IRL Press .
   Google Scholar
• Cálgaro-Helena , A. F. , Devienne , K. F. , Rodrigues , T. , Dorta , D. J. , Raddi , M. S. , Vilegas , W. , Uyemura , S. A. , Santos , A. C. and Curti , C. 2006 . Effects of isocoumarins isolated from Paepalanthus bromelioides on mitochondria: Uncoupling, and induction/inhibition of mitochondrial permeability transition . Chem. Biol. Interact , 161 : 155 – 164 .
   PubMed Web of Science ®Google Scholar
• Cathcart , R. , Schwiers , E. and Ames , B. N. 1983 . Detection of picomole levels of hydroperoxides using a fluorescent dichlorofluorescein assay . Anal. Biochem , 134 : 111 – 116 .
   PubMed Web of Science ®Google Scholar
• Chance , B. and Williams , G. R. 1956 . The respiratory chain and oxidative phosphorylation . Adv. Enzymol , 17 : 65 – 134 .
   PubMedGoogle Scholar
• Chen , Q. , Vazquez , E.J. , Moghaddas , S. , Hoppel , C. L. and Lesnefsky , E. 2003 . Production of reactive oxygen species by mitochondria: Central role of complex III . J. Biol. Chem , 278 : 36027 – 36031 .
   PubMed Web of Science ®Google Scholar
• Costa , L. G. , Giordano , G. , Tagliaferri , S. , Caglieri , A. and Mutti , A. 2008 . Polybrominated diphenyl ethers (PBDE) flame retardant: Environmental contamination, human body burden and potential adverse health effects . Acta Biomed , 79 : 172 – 183 .
   PubMedGoogle Scholar
• De Wit , C. A. 2002 . An overview of brominated flame retardants in the environment . Chemosphere , 46 : 583 – 624 .
   PubMed Web of Science ®Google Scholar
• Diamond , J. M , Latimer , H. A , Munkittrick , K. R , Thornton , K. W. , Bartell , S. M. and Kidd , K. A. 2011 . Prioritizing contaminants of emerging concern for ecological screening assesments . Environ. Toxicol. Chem , 30 : 2385 – 2394 .
   PubMed Web of Science ®Google Scholar
• Duchen , M. R. 2004 . Mitochondria in health and disease: Perspectives on a new mitochondrial biology . Mol. Aspects. Med , 4 : 365 – 451 .
   Google Scholar
• Hakk , H. , Huwe , J. K. and Larsen , G. L. 2009 . Absorption, distribution, metabolism and excretion (ADME) study with 2,2′, 4,4′, 5,6′-hexabromodiphenyl ether (BDE-154) in male Sprague –Dawley rats . Xenobiotica , 39 : 46 – 56 .
   PubMed Web of Science ®Google Scholar
• Halestrap , A. 2005 . Biochemistry: A pore way to die . Nature , 434 : 578 – 579 .
   PubMed Web of Science ®Google Scholar
• Harold , F. M. 1986 . The vital force: A study of bioenergetics , New York , NY : Freeman .
   Google Scholar
• Hatefi , Y. 1985 . The mitochondrial electron transport and oxidative phosphorylation system . Annu. Rev. Biochem , 54 : 1015 – 1069 .
   PubMed Web of Science ®Google Scholar
• Hissin , P. J. and Hilf , R. 1976 . A fluorimetric method for determination of oxidized and reduced glutathione in tissues . Anal. Biochem , 74 : 214 – 226 .
   PubMed Web of Science ®Google Scholar
• Hites , R. A. 2004 . Polybrominated diphenyl ethers in the environment and in people: A meta-analysis of concentrations . Environ. Sci. Technol , 38 : 945 – 956 .
   PubMed Web of Science ®Google Scholar
• Hu , X. Z. , Xu , Y. , Hu , D. C. , Hui , Y. and Yang , F. X. 2007 . Apoptosis induction on human hepatoma cells HepG2 of decabrominated diphenyl ether (PBDE-209) . Toxicol. Lett , 171 : 19 – 28 .
   PubMed Web of Science ®Google Scholar
• Huang , S. C. , Giordano , G. and Costa , L. G. 2010 . Comparative cytotoxicity and intracellular accumulation of five polybrominated siphenyl ether congeners in mouse cerebellar granule neurons . Toxicol. Sci , 114 : 124 – 132 .
   PubMed Web of Science ®Google Scholar
• Jocelyn , P. C. 1987 . Spectrophotometric assay of thiols . Methods Enzymol , 143 : 44 – 67 .
   PubMed Web of Science ®Google Scholar
• Kehrer , J. P. and Lund , L. G. 1994 . Cellular reducing equivalents and oxidative stress . Free Radical Biol. Med , 17 : 65 – 75 .
   PubMed Web of Science ®Google Scholar
• Lapidus , R. G. and Sokolove , P. M. 1993 . Spermine inhibition of the permeability transition of isolated rat liver mitochondria: An investigation of mechanism . Arch. Biochem. Biophys , 306 : 246 – 253 .
   PubMed Web of Science ®Google Scholar
• Lee , J. , Yu , B. P. and Herlihy , J. T. 1999 . Modulation of cardiac mitochondrial membrane fluidity by age and calorie intake . Free Radical Biol. Med , 26 : 260 – 265 .
   PubMed Web of Science ®Google Scholar
• Leist , M. , Single , B. , Castoldi , A.F. , Kuhnle , S. and Nicotera , P. 1997 . Intracellular adenosine triphosphate (ATP) concentration: A switch in the decision between apoptosis and necrosis . J. Exp. Clin. Med , 185 : 1481 – 1486 .
   Google Scholar
• Leite , S. , Martins , N. M. , Dorta , D. J. , Curti , C. , Uyemura , S. A. and Dos Santos , A. C. 2006 . Mitochondrial uncoupling by the sulindac metabolite, sulindac sulfide . Pharmacol. Toxicol , 99 : 294 – 299 .
   Google Scholar
• Lemasters , J. J. and Hackenbrock , C. R. 1976 . Continuous measurement and rapid kinetics of ATP synthesis in rat liver mitochondria, mitoplasts and inner membrane vesicles determined by firefly-luciferase luminescence . Eur. J. Biochem , 67 : 1 – 10 .
   PubMedGoogle Scholar
• Letcher , R. J. , Bustnes , J. O. , Dietz , R. , Jenssen , B. M. , Jorgensen , E. H. , Sonne , C. , Verreault , C. , Vijayan , M. M. and Gabrielsen , G. W. 2010 . Exposure and effects assessment of persistent organohalogen contaminants in arctic wildlife and fish . Sci. Total Environ , 408 : 2995 – 3043 .
   PubMed Web of Science ®Google Scholar
• Li , J. , Yu , H. , Zhao , Y. , Zhang , G. and Wu , Y. 2008 . Levels of polybrominated diphenyl ethers (PBDEs) in breast milk from Beijing, China . Chemosphere , 73 : 182 – 186 .
   PubMed Web of Science ®Google Scholar
• Ma , S. , Yu , Z. , Zhong , X. , Ren , G. , Peng , P. , Shen , G. and Fu , J. 2012 . Levels and congeners profiles of polybrominated diphenyl ethers (PBDEs) in breast milk from Shangai: Implications for exposure route of higher brominated BDEs . Environ Int , 47 : 72 – 77 .
   Web of Science ®Google Scholar
• Madia , F. , Giordano , G. , Fattori , V. , Vitalone , A. , Branchi , I. , Capone , F. and Costa , L. G. 2004 . Differential in vitro neurotoxicity of the flame retardant PBDE-99 and the PCB Aroclor 1254 in human astrocytoma cells . Toxicol Lett , 154 : 11 – 21 .
   PubMed Web of Science ®Google Scholar
• Meironyté , D. , Norén , K. and Bergman , Å. 1999 . Analysis of polybrominated diphenyl ethers in Swedish human milk. A time-related trend study, 1972–1997 . J. Toxicol. Environ. Health A , 58 : 329 – 341 .
   PubMed Web of Science ®Google Scholar
• Norstrom , R. J. , Simon , M. , Moisey , J. , Wakeford , B. and Weseloh , D. V. C. 2002 . Geographical distribution (2000) and temporal trends (1981–2000) of brominated diphenyl ethers in Great Lakes herring gull eggs . Environ Sci Technol , 36 : 4783 – 4789 .
   PubMed Web of Science ®Google Scholar
• Oliveira , H. C. , Cosso , R. G. , Alberici , L. C. , Maciel , E. N. , Salerno , A. G. , Dorighello , G. G. , Velho , J. A. , De Faria , E. C. and Vercesi , A. E. 2005 . Oxidative stress in atherosclerosis-prone mouse is due to low antioxidant capacity of mitochondria . FASEB J , 19 : 278 – 280 .
   PubMedGoogle Scholar
• Parolini , M. , Pedriali , A. and Binelli , A. 2012 . Variation of antioxidant activity in Dreissena polymorpha specimens exposed to 2,2′, 4,4′, 5,6′-hexa BDE (BDE-154) . Water Air Soil Pollut , 223 : 3067 – 3076 .
   Web of Science ®Google Scholar
• Pedersen , P. L. , Greenawalt , J. W. , Reynafarje , B. , Hullihen , J. , Decker , G. L. , Soper , J. W. and Bustamente , E. 1978 . Preparation and characterization of mitochondria and submitochondrial particles of rat liver and liver-derived tissues . Methods Cell. Biol , 20 : 411 – 481 .
   PubMedGoogle Scholar
• Pereira , L.C. , Souza , A.O. and Dorta , D.J. 2013 . Polybrominated diphenyl ether congener (BDE-100) induces mitochondrial impairment . Basic Clin. Pharmacol. Toxicol , doi: 10.1111/bcpt.12046
   PubMed Web of Science ®Google Scholar
• Pestana , C. R. , Borges , K. B. , Fonseca , P. and Oliveira , D. P. 2008 . Retardantes de chama bromados—uma revisão sobre éteres de difenilas polibromadas . Rev. Brasil Toxicol , 21 : 41 – 8 .
   Google Scholar
• Rodil , R. , Quintana , J.B. , Concha-Graña , E. , López-Mahía , P. , Muniategui-Lorenzo , S. and Prada-Rodríguez , D. 2012 . Emerging pollutants in sewage, surface and drinking water in Galicia (NW Spain) . Chemosphere , 86 : 1040 – 1049 .
   PubMed Web of Science ®Google Scholar
• Rodrigues , T. , Santos , A. C. , Pigoso , A. A. , Mingatto , F. E. , Uyemura , S. A. and Curti , C. 2002 . Thioridazine interacts with the membrane of mitochondria acquiring antioxidant activity toward apoptosis—Potentially implicated mechanisms . Br. J. Pharmacol , 136 : 136 – 142 .
   PubMed Web of Science ®Google Scholar
• Scatena , R. , Bottoni , P. , Botta , G. , Martorana , G. E. and Giardina , B. 2007 . The role of mitochondria in pharmacotoxicology: A reevaluation of an old, newly emerging topic . Am. J. Physiol Cell Physiol , 293 : 12 – 21 .
   PubMed Web of Science ®Google Scholar
• Scatena , R. 2012 . “ Mitochondria and drugs ” . In Advances in mitochondrial medicine , Edited by: Scatena , R. , Bottoni , P. and Giradina , B. 329 – 346 . New York , NY : Springer .
   Google Scholar
• Sellström , U. , Jansson , B. , Kierkegaard , A. , De Wit , C. , Odsjö , T. and Olsson , M. 1993 . Polybrominated diphenyl ethers (PBDE) in biological samples from the Swedish environment . Chemosphere , 26 : 1703 – 1718 .
   Web of Science ®Google Scholar
• Shao , J. , White , C. C. , Dabrowski , M. J. , Kavanagh , T. J. , Eckert , M. L. and Gallagher , E. P. 2008 . The role of mitochondrial and oxidative injury in BDE-47 toxicity to human fetal liver hematopoietic stem cells . Toxicol. Sci , 101 : 81 – 90 .
   PubMed Web of Science ®Google Scholar
• Shen , H. , Ding , G. , Han , G. , Wang , X. , Xu , X. , Han , J. , Lou , X. , Xu , C. and Cai , D. 2010 . Distribution of PCDD\Fs, PCBs, PBDEs and organochorine residues in children's blood from Zheijiang . Chemosphere , 80 : 170 – 175 .
   PubMed Web of Science ®Google Scholar
• Siddiqi , M. A. , Laessig , R. H. and Reed , K. D. 2003 . Polybrominated diphenyl ethers (PBDEs): New pollutants—Old diseases . Clin. Med. Res , 1 : 281 – 290 .
   PubMedGoogle Scholar
• Sjödin , A. , Jones , R. S. , Focant , J. F. , Lapeza , C. , Wang , R. Y. , McGahee , E. E. , Zhang , Y. , Turner , W. E. , Slazyk , B. , Needham , L. L. and Patterson , D. G. J. R. 2004 . Retrospective time-trend study of polybrominated diphenyl ether and polybrominated and polychlorinated biphenyl levels in human serum from the United States . Environ. Health Perspect , 112 : 655 – 658 .
   Google Scholar
• Slavík , J. 1982 . Anilinonaphthalene sulfonate as a probe of membrane composition and function . Biochim. Biophys. Acta , 694 : 1 – 25 .
   PubMed Web of Science ®Google Scholar
• Teclechiel , D. , Sundström , M. and Marsh , G. 2008 . Synthesis of polybrominated diphenyl ethers via symmetrical tetra- and hexabrominated diphenyliodonium salts . Chemosphere , 74 : 421 – 427 .
   PubMed Web of Science ®Google Scholar
• U.S. Environmental Protection Agency. 2006. Polybrominated diphenyl ethers (PBDEs). Project Plan Office of Prevention, Pesticides, and Toxic Substances. March http://www.epa.gov/oppts/pbde (http://www.epa.gov/oppts/pbde)
   Google Scholar
• U.S. Environmental Protection Agency. 2008. Toxicological review of 2,2′,4,4′,5,5′-hexabromodiphenyl ether (BDE-153). In support of summary information on the Integrated Risk Information System (IRIS). June http://www.epa.gov/iris (http://www.epa.gov/iris)
   Google Scholar
• Vrkoslavová , J. , Demnerová , K. , Macková , M. , Zemanová , T. , Macek , T. , Hajslová , J. , Pulkrabová , J. , Hrádková , P. and Stiborová , H. 2010 . Absorption and translocation of polybrominated diphenyl ethers (PBDEs) by plants from contaminated sewage sludge . Chemosphere , 81 : 381 – 386 .
   PubMed Web of Science ®Google Scholar
• Wallace , K. B. and Starkov , A. A. 2000 . Mitochondrial targets of drug toxicity . Annu. Rev. Pharmacol. Toxicol , 40 : 353 – 388 .
   PubMed Web of Science ®Google Scholar
• Weihong , H. , Ping , H. , Aiguo , W. , Tao , X. , Bayi , X. and Xuemin , C. 2009 . Effects of PBDE-47 on cytoxicity and genotoxicity in human neuroblastoma cells . in vitro. Mutat. Res , 649 : 62 – 70 .
   Web of Science ®Google Scholar
• Wu , J.-P. , Luo , X.-J. , Zhang , Y. , Yu , M. , Chen , S.-J. , Mai , B.-X. and Yang , Z.-Y. 2009 . Biomagnification of Polybrominated diphenyl ethers (PBDEs) and polychlorinated biphenyls in a highly contaminated freshwater food web from South China . Environ. Pollut , 157 : 904 – 909 .
   PubMed Web of Science ®Google Scholar
• Zhou , T. , Ross , D. G. , Devito , M. J. and Crofton , K. M. 2001 . Effects of short-term in vivo exposure to polybrominated diphenyl ethers on thyroid hormones and hepatic enzyme activities in weanling rats . Toxicol. Sci , 61 : 76 – 82 .
   PubMed Web of Science ®Google Scholar
• Zoratti , M. and Szabò , I. 1995 . The mitochondrial permeability transition . Biochim. Biophys. Acta , 1241 : 139 – 176 .
   PubMed Web of Science ®Google Scholar