Development of a Screening System for the Detection of Chemically Induced DNA Methylation Alterations in a Zebrafish Liver Cell Line

REFERENCES

• Alders, M., Bliek, J., van der Lip, K., van der Bogaard, R., and Mannens, M. 2009. Determination of KCNQ1OT1 and H19 methylation levels in BWS and SRS patients using methylation-sensitive high-resolution melting analysis. Eur. J. Hum. Genet. 17: 467–473.
   PubMed Web of Science ®Google Scholar
• Anway, M. D., Cupp, A. S., Uzumcu, M., and Skinner, M. K. 2005. Epigenetic transgenerational actions of endocrine disruptors and mate fertility. Science 308: 1466–1469.
   PubMed Web of Science ®Google Scholar
• Baccarelli, A., and Bollati, V. 2009. Epigenetics and environmental chemicals. Curr. Opin. Pediatr. 21: 243–251.
   PubMed Web of Science ®Google Scholar
• Bollati, V., and Baccarelli, A. 2010. Environmental epigenetics. Heredity 105: 105–112.
   PubMed Web of Science ®Google Scholar
• Chen, H., Li, S. F., Liu, J., Diwan, B. A., Barrett, J. C., and Waalkes, M. P. 2004. Chronic inorganic arsenic exposure induces hepatic global and individual gene hypomethylation: Implications for arsenic hepatocarcinogenesis. Carcinogenesis 25: 1779–1786.
   PubMed Web of Science ®Google Scholar
• Christman, J. K. 2002. 5-Azacytidine and 5-aza-2’-deoxycytidine as inhibitors of DNA methylation: Mechanistic studies and their implications for cancer therapy. Oncogene 21: 5483–5495.
   PubMed Web of Science ®Google Scholar
• Chu, D. C., Chuang, C. K., Fu, J. B., Huang, H. S., Tseng, C. P., and Sun, C. F. 2002. The use of real-time quantitative polymerase chain reaction to detect hypermethylation of the CpG islands in the promoter region flanking the GSTP1 gene to diagnose prostate carcinoma. J. Urol. 167:1854–1858.
   PubMed Web of Science ®Google Scholar
• Davis, A., Murphy, C., Rosenstein, M., Wiegers, T., and Mattingly, C. 2008. The Comparative Toxicogenomics Database facilitates identification and understanding of chemical-gene-disease associations: Arsenic as a case study. BMC Med. Genomics 1: 48.
   PubMed Web of Science ®Google Scholar
• Dragan, Y. P., Campbell, H. A., Baker, K., Vaughan, J., Mass, M., and Pitot, H. C. 1994. Focal and nonfocal hepatic expression of placental glutathion-S-transferase in carcinogen-treated rats. Carcinogenesis 15: 2587–2591.
   PubMed Web of Science ®Google Scholar
• Ehrlich, M. 2002. DNA methylation in cancer: Too much, but also too little. Oncogene 21: 5400–5413.
   PubMed Web of Science ®Google Scholar
• Esteller, M., Corn, P. G., Baylin, S. B., and Herman, J. G. 2001. A gene hypermethylation profile of human cancer. Cancer Res 61: 3225–3229.
   PubMed Web of Science ®Google Scholar
• Esteller, M., and Herman, J. G. 2002. Cancer as an epigenetic disease: DNA methylation and chromatin alterations in human tumours. J. Pathol. 196: 1–7.
   PubMed Web of Science ®Google Scholar
• Giusti, R. M., Iwamoto, K., and Hatch, E. E. 1995. Diethylstilbestrol revisited—A review of the long-term health effects. Ann. Intern. Med. 122: 778–788.
   PubMed Web of Science ®Google Scholar
• Gronbaek, K., Hother, C., and Jones, P. A. 2007. Epigenetic changes in cancer. APMIS 115: 1039–1059.
   PubMed Web of Science ®Google Scholar
• Hamdi, M., Yoshinaga, M., Packianathan, C., Qin, J., Hallauer, J., McDermott, J. R., Yang, H. C., Tsai, K. J., and Liu, Z. J. 2012. Identification of an S-adenosylmethionine (SAM) dependent arsenic methyltransferase in Danio rerio. Toxicol Appl Pharmacol 262: 185–193.
   PubMed Web of Science ®Google Scholar
• Hanna, C. W., Bloom, M. S., Robinson, W. P., Kim, D., Parsons, P. J., Saal, F. S. V., Taylor, J. A., Steuerwald, A. J., and Fujimoto, V. Y. 2012. DNA methylation changes in whole blood is associated with exposure to the environmental contaminants, mercury, lead, cadmium and bisphenol A, in women undergoing ovarian stimulation for IVF. Hum. Reprod. 27: 1401–1410.
   PubMed Web of Science ®Google Scholar
• Henry, T. R., Nesbit, D. J., Heideman, W., and Peterson, R. E. 2001. Relative potencies of polychlorinated dibenzo-p-dioxin, dibenzofuran, and biphenyl congeners to induce cytochrome P4501A mRNA in a zebrafish liver cell line. Environ. Toxicol. Chem. 20: 1053–1058.
   PubMed Web of Science ®Google Scholar
• Jensen, E. V., and Jordan, V. C. 2003. The estrogen receptor: A model for molecular medicine. Clin. Cancer Res. 9: 1980–1989.
   PubMed Web of Science ®Google Scholar
• Jiang, M., Zhang, Y., Fei, J., Chang, X., Fan, W., Qian, X., Zhang, T., and Lu, D. 2010. Rapid quantification of DNA methylation by measuring relative peak heights in direct bisulfite-PCR sequencing traces. Lab. Invest. 90: 282–290.
   PubMed Web of Science ®Google Scholar
• Jirtle, R. L., and Skinner, M. K. 2007. Environmental epigenomics and disease susceptibility. Nat. Rev. Genet. 8: 253–262.
   PubMed Web of Science ®Google Scholar
• Kamiya, K., Sato, T., Nishimura, N., Goto, Y., Kano, K., and Iguchi, T. 1996. Expression of estrogen receptor and proto-oncogene messenger ribonucleic acids in reproductive tracts of neonatally diethylstilbestrol-exposed female mice with or without postpuberal estrogen administration. Exp. Clin. Endocrinol. Diabet. 104: 111–122.
   PubMedGoogle Scholar
• Karon, M., Sieger, L., Leimbroc.S, Finklest.Jz, Nesbit, M. E., and Swaney, J. J. 1973. 5-Azacytidine—New active agent for treatment of acute leukemia. Blood 42: 359–365.
   PubMed Web of Science ®Google Scholar
• Lee, J. S. 2007. GSTP1 promoter hypermethylation is an early event in breast carcinogenesis. Virchows Arch. 450: 637–642.
   PubMed Web of Science ®Google Scholar
• Li, L. C., and Dahiya, R. 2002. MethPrimer: Designing primers for methylation PCRs. Bioinformatics 18: 1427–1431.
   PubMed Web of Science ®Google Scholar
• Li, S. F., Hursting, S. D., Davis, B. J., McLachlan, J. A., and Barrett, J. C. 2003. Environmental exposure, DNA methylation, and gene regulation—Lessons from diethylstilbesterol-induced cancers. Epigenet. Cancer Prev. Early Detect. Risk Assess. 983: 161–169.
   Google Scholar
• Lopez, J., Percharde, M., Coley, H. M., Webb, A., and Crook, T. 2009. The context and potential of epigenetics in oncology. Br. J. Cancer 100: 571–577.
   PubMed Web of Science ®Google Scholar
• Lyons, B. P., Stentiford, G. D., Bignell, J., Goodsir, F., Sivyer, D. B., Devlin, M. J., Lowe, D., Beesley, A., Pascoe, C. K., Moore, M. N., and Garnacho, E. 2006. A biological effects monitoring survey of Cardigan Bay using flatfish histopathology, cellular biomarkers and sediment bioassays: Findings of the Prince Madog Prize 2003. Mar. Environ. Res. 62: S342–S346.
   PubMed Web of Science ®Google Scholar
• McClure, E. A., North, C. M., Kaminski, N. E., and Goodman, J. I. 2011. Changes in DNA methylation and gene expression during 2,3,7,8-tetrachlorodibenzo-p-dioxin-induced suppression of the lipopolysaccharide-stimulated IgM response in splenocytes. Toxicol. Sci. 120: 339–348.
   PubMed Web of Science ®Google Scholar
• Mirbahai, L., Williams, T. D., Zhan, H. Q., Gong, Z. Y., and Chipman, J. K. 2011a. Comprehensive profiling of zebrafish hepatic proximal promoter CpG island methylation and its modification during chemical carcinogenesis. BMC Genomics 12: 16.
   Web of Science ®Google Scholar
• Mirbahai, L., Yin, G. L., Bignell, J. P., Li, N., Williams, T. D., and Chipman, J. K. 2011b. DNA methylation in liver tumorigenesis in fish from the environment. Epigenetics 6: 1319–1333.
   PubMed Web of Science ®Google Scholar
• Morgan, H. D., Santos, F., Green, K., Dean, W., and Reik, W. 2005. Epigenetic reprogramming in mammals. Hum. Mol. Genet. 14: R47–R58.
   PubMed Web of Science ®Google Scholar
• Nagase, H., and Ghosh, S. 2008. Epigenetics: Differential DNA methylation in mammalian somatic tissues. FEBS J. 275: 1617–1623.
   PubMed Web of Science ®Google Scholar
• Nelson, K. G., Sakai, Y., Eitzman, B., Steed, T., and McLachlan, J. 1994. Exposure to diethylstilbestrol during a critical developmental period of the mouse reproductive tract leads to persistent induction of 2 estrogen-regulated genes. Cell Growth Differ. 5: 595–606.
   PubMedGoogle Scholar
• Nile, C. J., Read, R. C., Akil, M., Duff, G. W., and Wilson, A. G. 2008. Methylation status of a single CpG site in the IL6 promoter is related to IL6 messenger RNA levels and rheumatoid arthritis. Arthritis Rheumatism 58: 2686–2693.
   PubMed Web of Science ®Google Scholar
• Pitot, H. C., Dragan, Y., Sargent, L., and Xu, Y. H. 1991. Biochemical markers associated with the stages of promotion and progression during hepatocarcinogenesis in the rat. Environ. Health Perspect. 93: 181–189.
   PubMed Web of Science ®Google Scholar
• Reik, W., Dean, W., and Walter, J. 2001. Epigenetic reprogramming in mammalian development. Science 293: 1089–1093.
   PubMed Web of Science ®Google Scholar
• Schreer, A., Tinson, C., Sherry, J. P., and Schirmer, K. 2005. Application of Alamar blue/5-carboxyfluorescein diacetate acetoxymethyl ester as a noninvasive cell viability assay in primary hepatocytes from rainbow trout. Anal. Biochem. 344: 76–85.
   PubMed Web of Science ®Google Scholar
• Sharma, S., Kelly, T. K., and Jones, P. A. 2010. Epigenetics in cancer. Carcinogenesis 31:27–36.
   PubMed Web of Science ®Google Scholar
• Skinner, M. K., Manikkam, M., and Guerrero-Bosagna, C. 2011. Epigenetic transgenerational actions of endocrine disruptors. Reprod. Toxicol. 31: 337–343.
   PubMed Web of Science ®Google Scholar
• Small, H. J., Williams, T. D., Sturve, J., Chipman, J. K., Southam, A. D., Bean, T. P., Lyons, B. P., and Stentiford, G. D. 2010. Gene expression analyses of hepatocellular adenoma and hepatocellular carcinoma from the marine flatfish Limanda limanda. Dis. Aquat. Organisms 88: 127–141.
   PubMed Web of Science ®Google Scholar
• Southam, A. D., Easton, J. M., Stentiford, G. D., Ludwig, C., Arvanitis, T. N., and Viant, M. R. 2008. Metabolic changes in flatfish hepatic tumours revealed by NMR-based metabolomics and metabolic correlation networks. J. Proteome Res. 7: 5277–5285.
   PubMed Web of Science ®Google Scholar
• Steinmetz, K. L., Pogribny, I. P., James, S. J., and Pitot, H. C. 1998. Hypomethylation of the rat glutathione S-transferase pi(GSTP) promoter region isolated from methyl-deficient livers and GSTP-positive liver neoplasms. Carcinogenesis 19: 1487–1494.
   PubMed Web of Science ®Google Scholar
• Stentiford, G. D., Bignell, J. P., Lyons, B. P., and Feist, S. W. 2009. Site-specific disease profiles in fish and their use in environmental monitoring. Mar. Ecol. Prog. Ser. 381: 1–15.
   Web of Science ®Google Scholar
• Tischoff, I., and Tannapfel, A. 2008. DNA methylation in hepatocellular carcinoma. World J Gastroenterol 14: 1741–1748.
   PubMed Web of Science ®Google Scholar
• Tollefsen, K. E., Blikstad, C., Eikvar, S., Farmen Finne, E., and Katharina Gregersen, I. 2008. Cytotoxicity of alkylphenols and alkylated non-phenolics in a primary culture of rainbow trout (Onchorhynchus mykiss) hepatocytes. Ecotoxicol. Environ. Safety 69: 64–73.
   PubMed Web of Science ®Google Scholar
• Tollefsen, K. E., Petersen, K., and Rowland, S. J. 2012. Toxicity of synthetic naphthenic acids and mixtures of these to fish liver cells. Environ. Sci. Technol. 46: 5143–5150.
   PubMed Web of Science ®Google Scholar
• Valinluck, V., Tsai, H. H., Rogstad, D. K., Burdzy, A., Bird, A., and Sowers, L. C. 2004. Oxidative damage to methyl-CpG sequences inhibits the binding of the methyl-CpG binding domain (MBD) of methyl-CpG binding protein 2 (MeCP2). Nucleic Acids Res. 32: 4100–4108.
   PubMed Web of Science ®Google Scholar
• Xie, S. P., Wang, Z. J., Okano, M., Nogami, M., Li, Y., He, W. W., Okumura, K., and Li, E. 1999. Cloning, expression and chromosome locations of the human DNMT3 gene family. Gene 236: 87–95.
   PubMed Web of Science ®Google Scholar
• Zhao, C. Q., Young, M. R., Diwan, B. A., Coogan, T. P., and Waalkes, M. P. 1997. Association of arsenic-induced malignant transformation with DNA hypomethylation and aberrant gene expression. Proc. Natl. Acad. Sci. USA 94: 10907–10912.
   PubMed Web of Science ®Google Scholar