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Original Articles

Persistent Organochlorine Pesticide Exposure Related to a Formerly Used Defense Site on St. Lawrence Island, Alaska: Data from Sentinel Fish and Human Sera

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Pages 976-992 | Received 02 Feb 2015, Accepted 31 Mar 2015, Published online: 11 Aug 2015

REFERENCES

  • Arctic Monitoring and Assessment Programme. 2002. Artic Pollution 2002: Persistent organic pollutants, heavy metals, radioactivity, human health, changing pathways. Oslo, Norway: Arctic Monitoring and Assessment Programme (AMAP).
  • Arctic Monitoring and Assessment Programme. 2004. Assessment 2002: Persistent organic pollutants in the Arctic. Oslo, Norway: Arctic Monitoring and Assessment Programme (AMAP).
  • Arctic Monitoring and Assessment Programme. 2009. Assessment 2009: Human health in the Arctic. Oslo, Norway: Arctic Monitoring and Asessment Programme (AMAP).
  • Arctic Monitoring and Assessment Programme. 2014. Trends in Stockholm Convention persistent organic pollutants (POPs) in arctic air, human media and biota. Oslo, Norway: Arctic Monitoring and Asessment Programme (AMAP).
  • Bersamin, A., Zidenberg-Cherr, S., Stern, J. S., and Luick, B. R. 2007. Nutrient intakes are associated with adherence to a traditional diet among Yup’ik Eskimos living in remote Alaska Native communities: The CANHR Study. Int. J. Circumpolar Health 66: 62–70.
  • Bjerregaard, P., Dewailly, E., Ayotte, P., Pars, T., Ferron, L., and Mulvad, G. 2001. Exposure of Inuit in Greenland to organochlorines through the marine diet. J Toxicol. Environ. Health. A 62: 69–81.
  • Burkow, I. C., and Kallenborn, R. 2000. Sources and transport of persistent pollutants to the Arctic. Toxicol. Lett. 112–113:87–92.
  • Butler Walker, J., Seddon, L., McMullen, E., Houseman, J., Tofflemire, K., Corriveau, A., Weber, J.-P., Mills, C., Smith, S., and Van Oostdam, J. 2003. Organochlorine levels in maternal and umbilical cord blood plasma in Arctic Canada. Sci. Total Environ. 302: 27–52.
  • Carpenter, D. O., DeCaprio, A. P., O’Hehir, D., Akhtar, F., Johnson, G., Scrudato, R. J., Apatiki, L., Kava, J., Gologergen, J., and Miller, P. K. 2005. Polychlorinated biphenyls in serum of the Siberian Yupik people from St. Lawrence Island, Alaska. Int. J. Circumpolar Health 64: 322–335.
  • Castor, M. L., Smyser, M. S., Taualii, M. M., Park, A. N., Lawson, S. A., and Forquera, R. A. 2006. A nationwide population-based study identifying health disparities between American Indians/Alaska Natives and the general populations living in select urban counties. Am. J. Public Health 96: 1478–1484.
  • Centers for Disease Control and Prevention. 2005. Third report on human exposure to environmental chemicals. Atlanta, GA: U.S. Department of Health and Human Services, Centers for Disease Control and Prevention.
  • Damstra, T. 2002. Potential effects of certain persistent organic pollutants and endocrine disrupting chemicals on the health of children. J. Toxicol. Clin. Toxicol. 40: 457–465.
  • Dewailly, E., Ayotte, P., Bruneau, S., Laliberté, C., Muir, D., and Norstrom, R. J. 1993. Inuit exposure to organochlorines through the aquatic food chain in Arctic Quebec. Environ. Health Perspect. 101: 618–620.
  • Donaldson, S. G., Van Oostdam, J., Tikhonov, C., Feeley, M., Armstrong, B., Ayotte, P., Boucher, O., Bowers, W., Chan, L., Dallaire, F., Dallaire, R., Dewailly, É., Edwards, J., Egeland, G. M., Fontaine, J., Furgal, C., Leech, T., Loring, E., Muckle, G., Nancarrow, T., Pereg, D., Plusquellec, P., Potyrala, M., Receveur, O., and Shearer, R. G. 2010. Environmental contaminants and human health in the Canadian Arctic. Sci. Total Environ. 408: 5165–5234.
  • Ebbesson, S. O., Risica, P. M., Ebbesson, L. O., Kennish, J. M., and Tejero, M. E. 2005. Omega-3 fatty acids improve glucose tolerance and components of the metabolic syndrome in Alaskan Eskimos: The Alaska Siberia project. Int. J. Circumpolar Health 64: 396–408.
  • Elabbas, L. E., Finnilä, M. A., Herlin, M., Stern, N., Trossvik, C., Bowers, W. J., Nakai, J., Tuukkanen, J., Heimeier, R. A., Åkesson, A., and Håkansson, H. 2011. Perinatal exposure to environmental contaminants detected in Canadian Arctic human populations changes bone geometry and biomechanical properties in rat offspring. J. Toxicol. Environ. Health. A 74: 1304–1318.
  • Emeville, E., Giton, F., Giusti, A., Oliva, A., Fiet, J., Thome, J. P., Blanchet, P., and Multigner, L. 2013. Persistent organochlorine pollutants with endocrine activity and blood steroid hormone levels in middle-aged men. PLoS ONE 8(6): e66460.
  • Erber, E., Hopping, B. N., Beck, L., Sheehy, T., De Roose, E., and Sharma, S. 2010. Assessment of dietary adequacy in a remote Inuvialuit population. J. Hum. Nutr. Diet. 23: 35–42.
  • Eskenazi, B., Marks, A. R., Bradman, A., Fenster, L., Johnson, C., Barr, D. B., and Jewell, N. P. 2006. In utero exposure to dichlorodiphenyltrichloroethane (DDT) and dichlorodiphenyldichloroethylene (DDE) and neurodevelopment among young Mexican American children. Pediatrics 118: 233–241.
  • Falk, D. E., Yi, H., and Hiller-Sturmhofel, S. 2006. An epidemiologic analysis of co-occurring alcohol and tobacco use and disorders. Alcohol Res. Health 29: 162–171.
  • Flanagan Pritz, C. M., Schrlau, J. E., Massey Simonich, S. L., and Blett, T. F. 2014. Contaminants of emerging concern in fish from western U.S. and Alaskan national parks—Spatial distribution and health thresholds. J. Am. Water Resources Assoc. 50: 309–323.
  • Freire, C., Koifman, R. J., Sarcinelli, P. N., Rosa, A. C. S., Clapauch, R., and Koifman, S. 2013. Association between serum levels of organochlorine pesticides and sex hormones in adults living in a heavily contaminated area in Brazil. Int. J. Hyg. Environ. Health 217: 370–378.
  • Godduhn, A., and Duffy, L. K. 2003. Multi-generation health risks of persistent organic pollution in the far north: Use of the precautionary approach in the Stockholm Convention. Environ. Sci. Policy 6: 341–353.
  • Hardell, S., Tilander, H., Welfinger-Smith, G., Burger, J., and Carpenter, D. O. 2010. Levels of polychlorinated biphenyls (PCBs) and three organochlorine pesticides in fish from the Aleutian Islands of Alaska. PLoS ONE 5: e12396.
  • Hopping, B. N., Mead, E., Erber, E., Sheehy, C., Roache, C., and Sharma, S. 2010. Dietary adequacy of Inuit in the Canadian Arctic. J. Hum. Nutr. Diet. 23: 27–34.
  • Kelce, W. R., Stone, C. R., Laws, S. C., Gray, L. E., Kemppainen, J. A., and Wilson, E. M. 1995. Persistent DDT metabolite p,p’-DDE is a potent androgen receptor antagonist. Nature 375: 581–585.
  • Kidd, K. A., Hesslein, R. H., Ross, B. J., Koczanski, K., Stephens, G. R., and Muir, D. C. G. 1998. Bioaccumulation of organochlorines through a remote freshwater food web in the Canadian Arctic. Environ. Pollut. 102: 91–103.
  • Kitts, D. D., Chen, X.-M., and Broda, P. 2012. Polyaromatic hydrocarbons of smoked cured muscle foods prepared by Canadian Tl’azt’en and Llheidli T’enneh First Nation Communities. J Toxicol. Environ. Health. A 75: 1249–1252.
  • Kucklick, J. R., Struntz, W. D., Becker, P. R., York, G. W., O’Hara, T. M., and Bohonowych, J. E. 2002. Persistent organochlorine pollutants in ringed seals and polar bears collected from northern Alaska. Sci. Total Environ. 287: 45–59.
  • Kuhnlein, H. V., Receveur, O., Soueida, R., and Egeland, G. M. 2004. Arctic indigenous peoples experience the nutrition transition with changing dietary patterns and obesity. J. Nutr. 134: 1447–1453.
  • Laird, B. D., Goncharov, A. B., and Chan, H. M. 2013. Body burden of metals and persistent organic pollutants among Inuit in the Canadian Arctic. Environ. Int. 59: 33–40.
  • Lemaire, G., Mnif, W., Mauvais, P., Balaguer, P., and Rahmani, R. 2006. Activation of alpha- and beta-estrogen receptors by persistent pesticides in reporter cell lines. Life Sci. 79: 1160–1169.
  • Lemaire, G., Terouanne, B., Mauvais, P., Michel, S., and Rahmani, R. 2004. Effect of organochlorine pesticides on human androgen receptor activation in vitro. Toxicol. Appl. Pharmacol. 196: 235–246.
  • Makhoul, Z., Kristal, A. R., Gulati, R., Luick, B., Bersamin, A., O’Brien, D., Hopkins, S. E., Stephensen, C. B., Stanhope, K. L., Havel, P. J., and Boyer, B. 2011. Associations of obesity with triglycerides and C-reactive protein are attenuated in adults with high red blood cell eicosapentaenoic and docosahexaenoic acids. Eur. J. Clin. Nutr. 65: 808–817.
  • Middaugh, J., Verbrugge, L., Haars, M., Schloss, M., and Yett, G. 2001. Assessment of exposure to persistent organic pollutants (POPs) in 5 Aleutian and Pribilof villages. State Alaska Epidemiol. Bull. 5: 1–18.
  • Miller, P. K., Waghiyi, V., Welfinger-Smith, G., Byrne, S. C., Kava, J., Gologergen, J., Eckstein, L., Scrudato, R., Chiarenzelli, J., Carpenter, D. O., and Seguinot-Medina, S. 2013. Community-based participatory research projects and policy engagement to protect environmental health on St Lawrence Island, Alaska. Int. J. Circumpolar Health 72(suppl.): e21656. http://dx.doi.org/10.3402/ijch.v72i0.21656.
  • Mrema, E. J., Rubino, F. M., Brambilla, G., Moretto, A., Tsatsakis, A. M., and Colosio, C. 2013. Persistent organochlorinated pesticides and mechanisms of their toxicity. Toxicology 307: 74–88.
  • Odland, J. O., Deutch, B., Hansen, J. C., and Burkow, I. C. 2003. The importance of diet on exposure to and effects of persistent organic pollutants on human health in the Arctic. Acta Paediatr. 92: 1255–1266.
  • Puertas, R., Lopez-Espinosa, M.-J., Cruz, F., Ramos, R., Freire, C., Pérez-García, M., Abril, A., Julvez, J., Salvatierra, M., Campoy, C., and Olea, N. 2010. Prenatal exposure to mirex impairs neurodevelopment at age of 4 years. NeuroToxicology 31: 154–160.
  • Ribas-Fito, N., Cardo, E., Sala, M., Eulalia de Muga, M., Mazon, C., Verdu, A., Kogevinas, M., Grimalt, J. O., and Sunyer, J. 2003. Breastfeeding, exposure to organochlorine compounds, and neurodevelopment in infants. Pediatrics 111: e580–e585.
  • Rubin, C. H., Lanier, A., Kieszak, S., Brock, J. W., Koller, K. R., Strosnider, H., Needham, L., Zahm, S., and Harpster, A. 2006. Breast cancer among Alaska Native women potentially exposed to environmental organochlorine chemicals. Int. J. Circumpolar Health 65: 18–27.
  • Rubin, C. H., Lanier, A., Socha, M., Brock, J. W., Kieszak, S., and Zahm, S. 2001. Exposure to persistent organochlorines among Alaska Native women. Int. J. Circumpolar Health 60: 157–169.
  • Salehi, F., Turner, M. C., Phillips, K. P., Wigle, D. T., Krewski, D., and Aronson, K. J. 2008. Review of the etiology of breast cancer with special attention to organochlorines as potential endocrine disruptors. J. Toxicol. Environ. Health B 11: 276–300.
  • Scrudato, R., Chiarenzelli, J., Miller, P., Alexander, C., Arnason, J., Zamzow, K., Zweifel, K., Gologergen, J., Kava, J., Waghiyi, V., and Carpenter, D. O. 2012. Contaminants at arctic formerly used defense sites. J. Local Glob. Health Sci. 1: 1–15.
  • Sovocool, G. W., Lewis, R. G., Harless, R. L., Wilson, N. K., and Zehr, R. D. 1977. Analysis of technical chlordane by gas chromatography/mass spectrometry. Anal. Chem. 49: 734–740.
  • Suk, W. A., Avakian, M. D., Carpenter, D., Groopman, J. D., Scammell, M., and Wild, C. P. 2004. Human exposure monitoring and evaluation in the Arctic: The importance of understanding exposures to the development of public health policy. Environ. Health Perspect. 112: 113–120.
  • Sullivan, K. M., Dean, A., and Soe, M. M. 2009. OpenEpi: A web-based epidemiologic and statistical calculator for public health. Public Health Rep. 124: 471–474.
  • Tashiro, S., and Matsumura, F. 1978. Metabolism of trans-nonachlor and related chlordane components in rat and man. Arch. Environ. Contam. Toxicol 7: 113–127.
  • Teilmann, G., Juul, A., Skakkebæk, N. E., and Toppari, J. 2002. Putative effects of endocrine disrupters on pubertal development in the human. Best Pract. Res. Clin. Endocrinol. Metab. 16: 105–121.
  • Torres-Sanchez, L., Schnaas, L., Rothenberg, S. J., Cebrian, M. E., Osorio-Valencia, E., Hernandez Mdel, C., Garcia-Hernandez, R. M., and Lopez-Carrillo, L. 2013. Prenatal p,p-DDE exposure and neurodevelopment among children 3.5-5 years of age. Environ. Health Perspect. 121: 263–268.
  • Van Oostdam, J., Gilman, A., Dewailly, E., Usher, P., Wheatley, B., Kuhnlein, H., Neve, S., Walker, J., Tracy, B., Feeley, M., Jerome, V., and Kwavnick, B. 1999. Human health implications of environmental contaminants in Arctic Canada: A review. Sci. Total Environ. 230: 1–82.
  • Van Oostdam, J. C., Dewailly, E., Gilman, A., Hansen, J. C., Odland, J. O., Chashchin, V., Berner, J., Butler-Walker, J., Lagerkvist, B. J., Olafsdottir, K., Soininen, L., Bjerregard, P., Klopov, V., and Weber, J. P. 2004. Circumpolar maternal blood contaminant survey, 1994–1997 organochlorine compounds. Sci. Total Environ. 330: 55–70.
  • Welfinger-Smith, G., Minholz, J. L., Byrne, S., Waghiyi, V., Gologergen, J., Kava, J., Apatiki, M., Ungott, E., Miller, P. K., Arnason, J. G., and Carpenter, D. O. 2011. Organochlorine and metal contaminants in traditional foods from St. Lawrence Island, Alaska. J. Toxicol. Environ. Health A 74: 1195–214.
  • Wilson, R., Allen-Gil, S., Griffin, D., and Landers, D. 1995. Organochlorine contaminants in fish from an Arctic lake in Alaska, USA. Sci. Total Environ. 160–161:511–519.

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