358
Views
15
CrossRef citations to date
0
Altmetric
Original Articles

Taxonomic applicability of inflammatory cytokines in adverse outcome pathway (AOP) development

, , , , &
Pages 184-196 | Received 22 Sep 2015, Accepted 06 Nov 2015, Published online: 25 Feb 2016

References

  • Adeleye, Y., Andersen, M., Clewell, R., Davies, M., Dent, M., Edwards, S., Fowler, P., Malcomber, S., Nicol, B., Scott, A., Scott, S., Sun, B., Westmoreland, C., White, A., Zhang, Q., and Carmichael, P. L. 2015. Implementing Toxicity Testing in the 21st Century (TT21C): Making safety decisions using toxicity pathways, and progress in a prototype risk assessment. Toxicology 332: 102–111.
  • Angrish, M. M., Madden, M. C., and Pleil, J. D. 2015. Probe molecule (PrM) approach in adverse outcome pathway (AOP) based high-throughput screening (HTS): In vivo discovery for developing in vitro target methods. Chem. Res. Toxicol. 28: 551–559.
  • Arai, K. I., Lee, F., Miyajima, A., Miyatake, S., Arai, N., and Yokota, T. 1990. Cytokines: Coordinators of immune and inflammatory responses. Annu. Rev. Biochem. 59: 783–836.
  • Berg, E. L., Kunkel, E. J., Hytopoulos, E., and Plavec, I. 2006. Characterization of compound mechanisms and secondary activities by BioMAP analysis. J. Pharmacol. Toxicol. Methods 53: 67–74.
  • Bouman, A., Heineman, M. J., and Faas, M. M. 2005. Sex hormones and the immune response in humans. Hum. Reprod. Update 11: 411–423.
  • Boverhof, D. R., Burgoon, L. D., Tashiro, C., Sharratt, B., Chittim, B., Harkema, J. R., Mendrick, D. L., and Zacharewski, T. R. 2006. Comparative toxicogenomic analysis of the hepatotoxic effects of TCDD in Sprague Dawley rats and C57BL/6 mice. Toxicol. Sci. 94: 398–416.
  • Chen, W., Zhang, Q., Kaplan, B. L., Baker, G. L., and Kaminski, N. E. 2014. Induced T cell cytokine production is enhanced by engineered nanoparticles. Nanotoxicology 8(suppl. 1): 11–23.
  • Chowdhury, F., Williams, A., and Johnson, P. 2009. Validation and comparison of two multiplex technologies, Luminex and Mesoscale Discovery, for human cytokine profiling. J. Immunol. Methods 340: 55–64.
  • Chung, K. F., and Barnes, P. J. 1999. Cytokines in asthma. Thorax 54: 825–857.
  • Csaba, G. 2014. Hormones in the immune system and their possible role. A critical review. Acta Microbiol. Immunol. Hung. 61: 241–260.
  • Dorshkind, K., and Horseman, N. D. 2000. The roles of prolactin, growth hormone, insulin-like growth factor-I, and thyroid hormones in lymphocyte development and function: Insights from genetic models of hormone and hormone receptor deficiency. Endocr. Rev. 21: 292–312.
  • Duramad, P., and Holland, N. T. 2011. Biomarkers of immunotoxicity for environmental and public health research. Int. J. Environ. Res. Public Health 8: 1388–1401.
  • Fischer, S. K., Joyce, A., Spengler, M., Yang, T. Y., Zhuang, Y., Fjording, M. S., and Mikulskis, A. 2015. Emerging technologies to increase ligand binding assay sensitivity. Am. Assoc. Pharm. Sci. (AAPS) J. 17: 93–101.
  • Foster, B., Prussin, C., Liu, F., Whitmire, J. K., and Whitton, J. L. 2007. Detection of intracellular cytokines by flow cytometry. Curr. Protocols Immunol. Chapter 6: Unit 6 24. DOI 10.1002/0471142735.im0624s78
  • Gangur, V., Birmingham, N. P., and Thanesvorakul, S. 2002. Chemokines in health and disease. Vet. Immunol. Immunopathol. 86: 127–136.
  • Gerard, C., and Rollins, B. J. 2001. Chemokines and disease. Nat. Immunol. 2: 108–115.
  • Goodman, R. B., Strieter, R. M., Martin, D. P., Steinberg, K. P., Milberg, J. A., Maunder, R. J., Kunkel, S. L., Walz, A., Hudson, L. D., and Martin, T. R. 1996. Inflammatory cytokines in patients with persistence of the acute respiratory distress syndrome. Am. J. Respir. Crit. Care Med. 154: 602–611.
  • Hofmann, W., Koblinger, L., and Martonen, T. B. 1989. Structural differences between human and rat lungs: implications for Monte Carlo modeling of aerosol deposition. Health Phys. 57(suppl. 1): 41–46; discussion 46–47.
  • Houck, K. A., Dix, D. J., Judson, R. S., Kavlock, R. J., Yang, J., and Berg, E. L. 2009. Profiling bioactivity of the ToxCast chemical library using BioMAP primary human cell systems. J. Biomol. Screen 14: 1054–1066.
  • Huang, Q., and Riviere, J. E. 2014. The application of allometric scaling principles to predict pharmacokinetic parameters across species. Expert Opin. Drug Metab. Toxicol. 10: 1241–1253.
  • Judson, R., Houck, K., Martin, M., Knudsen, T., Thomas, R. S., Sipes, N., Shah, I., Wambaugh, J., and Crofton, K. 2014. In vitro and modelling approaches to risk assessment from the U.S. Environmental Protection Agency ToxCast programme. Basic Clin. Pharmacol. Toxicol. 115: 69–76.
  • LaLone, C. A., Berninger, J. P., Villeneuve, D. L., and Ankley, G. T. 2014. Leveraging existing data for prioritization of the ecological risks of human and veterinary pharmaceuticals to aquatic organisms. Philos. Trans. R. Soc. Lond. B Biol. Sci. 369: 20140022. http://dx.doi.org/10.1098/rstb.2014.0022
  • Locatelli, V., Bresciani, E., Tamiazzo, L., and Torsello, A. 2010. Central nervous system-acting drugs influencing hypothalamic–pituitary–adrenal axis function. Endocr. Dev. 17: 108–120.
  • Luckey, S. W., and Petersen, D. R. 2001. Activation of Kupffer cells during the course of carbon tetrachloride-induced liver injury and fibrosis in rats. Exp. Mol. Pathol. 71: 226–240.
  • Luebke, R. W., Chen, D. H., Dietert, R., Yang, Y., King, M., Luster, M. I., and Immunotoxicology Workgroup. 2006. The comparative immunotoxicity of five selected compounds following developmental or adult exposure. J. Toxicol. Environ. Health B 9: 1–26.
  • Madden, M. C., Stevens, T., Case, M., Schmitt, M., Diaz-Sanchez, D., Bassett, M., Montilla, T. S., Berntsen, J., and Devlin, R. B. 2014. Diesel exhaust modulates ozone-induced lung function decrements in healthy human volunteers. Part. Fibre Toxicol. 11: 37.
  • Martignoni, M., Groothuis, G. M., and de Kanter, R. 2006. Species differences between mouse, rat, dog, monkey and human CYP-mediated drug metabolism, inhibition and induction. Expert Opin. Drug Metab. Toxicol. 2: 875–894.
  • Mestas, J., and Hughes, C. C. 2004. Of mice and not men: Differences between mouse and human immunology. J. Immunol. 172: 2731–2738.
  • Mladineo, I., and Block, B. A. 2010. Expression of cytokines IL-1beta and TNF-alpha in tissues and cysts surrounding Didymocystis wedli (Digenea, Didymozoidae) in the Pacific bluefin tuna (Thunnus orientalis). Fish Shellfish Immunol. 29: 487–493.
  • Mnif, W., Hassine, A. I., Bouaziz, A., Bartegi, A., Thomas, O., and Roig, B. 2011. Effect of endocrine disruptor pesticides: A review. Int. J. Environ. Res. Public Health 8: 2265–2303.
  • Mora, J., Given Chunyk, A., Dysinger, M., Purushothama, S., Ricks, C., Osterlund, K., and Theobald, V. 2014. Next generation ligand binding assays—Review of emerging technologies’ capabilities to enhance throughput and multiplexing. Am. Assoc. Pharm. Sci (AAPS) J. 16: 1175–1184.
  • Moser, V. C., Stewart, N., Freeborn, D. L., Crooks, J., MacMillan, D. K., Hedge, J. M., Wood, C. E., McMahen, R. L., Strynar, M. J., and Herr, D. W. 2015. Assessment of serum biomarkers in rats after exposure to pesticides of different chemical classes. Toxicol. Appl. Pharmacol. 282: 161–174.
  • Muller, P. Y., and Brennan, F. R. 2009. Safety assessment and dose selection for first-in-human clinical trials with immunomodulatory monoclonal antibodies. Clin. Pharmacol. Ther. 85: 247–258.
  • Nan, Y. M., Kong, L. B., Ren, W. G., Wang, R. Q., Du, J. H., Li, W. C., Zhao, S. X., Zhang, Y. G., Wu, W. J., Di, H. L., Li, Y., and Yu, J. 2013. Activation of peroxisome proliferator activated receptor alpha ameliorates ethanol mediated liver fibrosis in mice. Lipids Health Dis. 12: 11.
  • Perkins, E. J., Chipman, J. K., Edwards, S., Habib, T., Falciani, F., Taylor, R., Van Aggelen, G., Vulpe, C., Antczak, P., and Loguinov, A. 2011. Reverse engineering adverse outcome pathways. Environ. Toxicol. Chem. 30: 22–38.
  • Phadnis-Moghe, A. S., Crawford, R. B., and Kaminski, N. E. 2014. Suppression of human B cell activation by 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) involves altered regulation of B cell lymphoma-6 (BCL-6). Toxicol. Sci. 144: 39–50.
  • Pleil, J. D., Beauchamp, J. D., Miekisch, W., and Funk, W. E. 2015. Adapting biomarker technologies to adverse outcome pathways (AOPs) research: Current thoughts on using in vivo discovery for developing in vitro target methods. J. Breath. Res. 9: 039001.
  • Pleil, J. D., and Sobus, J. R. 2013. Estimating lifetime risk from spot biomarker data and intraclass correlation coefficients (ICC). J. Toxicol. Environ. Health A 76: 747–766.
  • Pleil, J. D., Sobus, J. R., Stiegel, M. A., Hu, D., Oliver, K. D., Olenick, C., Strynar, M., Clark, M., Madden, M. C., and Funk, W. E. 2014. Estimating common parameters of lognormally distributed environmental and biomonitoring data: Harmonizing disparate statistics from publications. J. Toxicol. Environ. Health B 17: 341–368.
  • Pleil, J. D., Williams, M. A., and Sobus, J. R. 2012. Chemical Safety for Sustainability (CSS): Human in vivo biomonitoring data for complementing results from in vitro toxicology—A commentary. Toxicol. Lett. 215: 201–207.
  • Procaccini, C., Pucino, V., De Rosa, V., Marone, G., and Matarese, G. 2014. Neuro-endocrine networks controlling immune system in health and disease. Front. Immunol. 5: 143.
  • Raphael, I., Nalawade, S., Eagar, T. N., and Forsthuber, T. G. 2014. T cell subsets and their signature cytokines in autoimmune and inflammatory diseases. Cytokine 74: 5–17.
  • Rappaport, S. M. 2012. Discovering environmental causes of disease. J. Epidemiol. Commun. Health 66: 99–102.
  • Rappaport, S. M., and Smith, M. T. 2010. Epidemiology. Environment and disease risks. Science 330: 460–461.
  • Rissin, D. M., Kan, C. W., Campbell, T. G., Howes, S. C., Fournier, D. R., Song, L., Piech, T., Patel, P. P., Chang, L., Rivnak, A. J., Ferrell, E. P., Randall, J. D., Provuncher, G. K., Walt, D. R., and Duffy, D. C. 2010. Single-molecule enzyme-linked immunosorbent assay detects serum proteins at subfemtomolar concentrations. Nat. Biotechnol. 28: 595–599.
  • Romagnani, S. 2000. T-cell subsets (Th1 versus Th2). Ann. Allergy Asthma Immunol. 85: 9–18; quiz 18, 21.
  • Shvedova, A. A., Yanamala, N., Murray, A. R., Kisin, E. R., Khaliullin, T., Hatfield, M. K., Tkach, A. V., Krantz, Q. T., Nash, D., King, C., Ian Gilmour, M., and Gavett, S. H. 2013. Oxidative stress, inflammatory biomarkers, and toxicity in mouse lung and liver after inhalation exposure to 100% biodiesel or petroleum diesel emissions. J. Toxicol. Environ. Health A 76: 907–921.
  • Snyder-Talkington, B. N., Qian, Y., Castranova, V., and Guo, N. L. 2012. New perspectives for in vitro risk assessment of multiwalled carbon nanotubes: Application of coculture and bioinformatics. J. Toxicol. Environ. Health B 15: 468–492.
  • Sternberg, E. M. 2001. Neuroendocrine regulation of autoimmune/inflammatory disease. J. Endocrinol. 169: 429–435.
  • Stiegel, M. A., Pleil, J. D., Sobus, J. R., Morgan, M. K., and Madden, M. C. 2015. Analysis of inflammatory cytokines in human blood, breath condensate, and urine using a multiplex immunoassay platform. Biomarkers 20:35–46. doi: 10.3109/1354750X.2014.988646
  • Stiegel, M. A., Pleil, J. D., Sobus, J. R., and Madden, M. C., 2016. Inflammatory Cytokines and White Blood Cell Counts Response to Environmental Levels of Diesel Exhaust and Ozone Inhalation Exposures, PLoS ONE (submitted).
  • Suntharalingam, G., Perry, M. R., Ward, S., Brett, S. J., Castello-Cortes, A., Brunner, M. D., and Panoskaltsis, N. 2006. Cytokine storm in a phase 1 trial of the anti-CD28 monoclonal antibody TGN1412. N. Engl. J. Med. 355: 1018–1028.
  • Tarrant, J. M. 2010. Blood cytokines as biomarkers of in vivo toxicity in preclinical safety assessment: Considerations for their use. Toxicol. Sci. 117: 4–16.
  • Villarino, A. V., Kanno, Y., Ferdinand, J. R., and O’Shea, J. J. 2015. Mechanisms of Jak/STAT signaling in immunity and disease. J. Immunol. 194: 21–27.
  • Villeneuve, D. L., Crump, D., Garcia-Reyero, N., Hecker, M., Hutchinson, T. H., LaLone, C. A., Landesmann, B., Lettieri, T., Munn, S., Nepelska, M., Ottinger, M. A., Vergauwen, L., and Whelan, M. 2014a. Adverse outcome pathway (AOP) development I: Strategies and principles. Toxicol. Sci. 142: 312–320.
  • Villeneuve, D. L., Crump, D., Garcia-Reyero, N., Hecker, M., Hutchinson, T. H., LaLone, C. A., Landesmann, B., Lettieri, T., Munn, S., Nepelska, M., Ottinger, M. A., Vergauwen, L., and Whelan, M. 2014b. Adverse outcome pathway development II: Best practices. Toxicol. Sci. 142: 321–330.
  • Vos, J. G., and van Loveren, H. 1995. Markers for immunotoxic effects in rodents and man. Toxicol. Lett. 82–83:385–394.
  • Wasinger, V. C., Zeng, M., and Yau, Y. 2013. Current status and advances in quantitative proteomic mass spectrometry. Int. J. Proteomics 2013: 180605.
  • Wiedermann, F. J., Mayr, A. J., Kaneider, N. C., Fuchs, D., Mutz, N. J., and Schobersberger, W. 2004. Alveolar granulocyte colony-stimulating factor and alpha-chemokines in relation to serum levels, pulmonary neutrophilia, and severity of lung injury in ARDS. Chest 125: 212–219.
  • World Health Organization. 2012. Guidance for immunotoxicity risk assessment for chemicals. The Harmonization Project. Geneva, Switzerland: World Heatlth Organization.
  • Yoon, K., Kwack, S. J., Kim, H. S., and Lee, B. M. 2014. Estrogenic endocrine-disrupting chemicals: Molecular mechanisms of actions on putative human diseases. J. Toxicol. Environ. Health B 17: 127–174.
  • Yoshie, O. 2000. Role of chemokines in trafficking of lymphocytes and dendritic cells. Int. J. Hematol. 72: 399–407.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.