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Original Articles

Analysis of the miRNA–mRNA networks in malignant transformation BEAS-2B cells induced by alpha-particles

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References

  • Antonelli, F., Campa, A., Esposito, G., Giardullo, P., Belli, M., Dini, V., Meschini, S., Simone, G., Sorrentino, E., Gerardi, S., Cirrone, G. A., and Tabocchini, M. A. 2015. Induction and repair of DNA DSB as revealed by γ-H2AX phosphorylation fin human fibroblasts exposed to low- and high-LET radiation: Relationship with early and delayed reproductive cell death. Radiat. Res. 183: 417–431.
  • Cao, M., Li, Y., Lu, H., Meng, Q., Wang, L., Cai, L., and Dong, X. 2014. MiR-23a-mediated migration/invasion is rescued by its target, IRS-1, in non-small cell lung cancer cells. J. Cancer Res. Clin. Oncol. 140: 1661–1670.
  • Chen, Z., Wu, Y., Meng, Q., and Xia, Z. 2015. Elevated microRNA-25 inhibits cell apoptosis in lung cancer by targeting RGS3. In Vitro Cell Dev. Biol. Anim. 52: 62–67.
  • Cui, F., Li, J., Chen, Q., Du, H., Zhang, S., Nie, J., Cao, J., Zhou, P., Hei, T. K., and Tong, J. 2012. Radon-induced alterations in micro-RNA expression profiles in transformed BEAS-2B cells. J. Toxicol. Environ. Health A 76: 107–119.
  • Dasgupta, S., Hoque, M. O., Upadhyay, S., and Sidransky, D. 2008. Mitochondrial cytochrome B gene mutation promotes tumor growth in bladder cancer. Cancer Res. 68: 700–706.
  • Dong, W., Yao, C., Teng, X., Chai, J., Yang, X., and Li, B. 2015. MiR-140-3p suppressed cell growth and invasion by downregulating the expression of ATP8A1 in non-small cell lung cancer. Tumour Biol. 37: 2973–2985.
  • Duport, P., Jiang, H., Shilnikova, N.S.,Krewski, D., and Zielinski, J. M. 2012. Database of radiogenic cancer in experimental animals exposed to low doses of ionizing radiation. J. Toxicol. Environ. Health B 15: 186–209.
  • Eisenreich, A., Zakrzewicz, A., Huber, K., Thierbach, H., Pepke, W., Goldin-Lang, P., Schultheiss, H. P., Pries, A., and Rauch, U. 2013. Regulation of pro-angiogenic tissue factor expression in hypoxia-induced human lung cancer cells. Oncol. Rep. 30: 462–470.
  • Fang, L., Cai, J., Chen, B., Wu, S., Li, R., Xu, X., Yang, Y., Guan, H., Zhu, X., Zhang, L., Yuan, J., Wu, J., and Li, M. 2015. Aberrantly expressed miR-582-3p maintains lung cancer stem cell-like traits by activating Wnt/beta-catenin signalling. Nat. Commun. 6: 8640.
  • Gentilella, A., Kozma, S.C., and Thomas, G. 2015. A liaison between mTOR signaling, ribosome biogenesis and cancer. Biochim. Biophys. Acta 1849: 812–820.
  • Gerstein, M.B., Kundaje, A., Hariharan, M., Landt, S.G., Yan, K.K., Cheng, C., Mu, .J.,Khurana, E., Rozowsky, J., Alexander, R., Min, R., Alves, P., Abyzov, A., Addleman, N.,Bhardwaj, N., Boyle, A.P., Cayting, P., Charos, A., Chen, D.Z., Cheng, Y., Clarke, D.,Eastman, C., Euskirchen, G., Frietze, S., Fu, Y., Gertz, J., Grubert, F., Harmanci, A., Jain, P., Kasowski, M., Lacroute, P., Leng, J., Lian, J., Monahan, H., O’Geen, H., Ouyang, Z.,Partridge, E.C., Patacsil, D., Pauli, F., Raha, D., Ramirez, L., Reddy, T.E., Reed, B., Shi, M., Slifer, T., Wang, J., Wu, L., Yang, X., Yip, K.Y., Zilberman-Schapira, G., Batzoglou, S., Sidow, A., Farnham, P.J., Myers, R.M., Weissman, S.M., and Snyder, M. 2012. Architectureof the human regulatory network derived from ENCODE data. Nature 489: 91–100.
  • Goobie, G. C., Bernatsky, S., Ramsey-Goldman, R., and Clarke, A. E. 2015. Malignancies in systemic lupus erythematosus: a 2015 update. Curr. Opin. Rheumatol. 27: 454–460.
  • Herbertz, S., Sawyer, J. S., Stauber, A. J., Gueorguieva, I., Driscoll, K. E., Estrem, S. T., Cleverly, A. L., Desaiah, D., Guba, S. C., Benhadji, K. A., Slapak, C. A., and Lahn, M. M. 2015. Clinical development of galunisertib (LY2157299 monohydrate), a small molecule inhibitor of transforming growth factor-beta signaling pathway. Drug Des. Dev. Ther. 9: 4479–4499.
  • Jassam, S. A., Maherally, Z., Smith, J. R., Ashkan, K., Roncaroli, F., Fillmore, H. L., and Pilkington, G. J. 2015. TNF-alpha enhancement of CD62E mediates adhesion of non-small cell lung cancer cells to brain endothelium via CD15 in lung-brain metastasis. Neuro Oncol. 18: 679–690.
  • Jeong, H. C. 2014. Clinical aspect of microRNA in lung cancer. Tuberc. Respir. Dis. (Seoul). 77: 60–64.
  • Kang, H. W., Crawford, M., Fabbri, M., Nuovo, G., Garofalo, M., Nana-Sinkam, S. P., and Friedman, A. 2013. A mathematical model for microRNA in lung cancer. PLoS ONE 8: e53663.
  • Katoh, Y., and Katoh, M. 2004. Identification and characterization of ARHGAP27 gene in silico. Int. J. Mol. Med. 14: 943–947.
  • Kim, J. H., Cho, E. B., Lee, J., Jung, O., Ryu, B. J., Kim, S. H., Cho, J. Y., Ryou, C., and Lee, S. Y. 2015. Emetine inhibits migration and invasion of human non-small-cell lung cancer cells via regulation of ERK and p38 signaling pathways. Chem. Biol. Interact. 242: 25–33.
  • Kitajima, S., Iwata, Y., Furuichi, K., Sagara, A., Shinozaki, Y., Toyama, T., Sakai, N., Shimizu, M., Sakurai, T., Kaneko, S., and Wada, T. 2015. Messenger RNA expression profile of sleep-related genes in peripheral blood cells in patients with chronic kidney disease. Clin. Exp. Nephrol. 20: 218–225.
  • Kreuzer, M., Fenske, N., Schnelzer, M., and Walsh, L. 2015. Lung cancer risk at low radon exposure rates in German uranium miners. Br. J. Cancer. 113: 1367–1369.
  • Lemjabbar-Alaoui, H., Hassan, O. U., Yang, Y. W., and Buchanan, P. 2015. Lung cancer: Biology and treatment options. Biochim. Biophys. Acta 1856: 189–210.
  • Leppert, U., and Eisenreich, A. 2015. The role of tissue factor isoforms in cancer biology. Int. J. Cancer 137: 497–503.
  • Li, F., Chen, X., Xu, B., and Zhou, H. 2015. Curcumin induces p53-independent necrosis in H1299 cells via a mitochondria-associated pathway. Mol. Med. Rep. 12: 7806–7814.
  • Li, B., Sun, J., W Hong., Cheng Y., Xue, L., Cheng, Z., Wan, J., Wang, A., Hei, T. K., and Tong, J. 2012. Radon-induced reduced apoptosis in human bronchial epithelial cells with knock-down of mitochondria DNA. J. Toxicol. Environ. Health A 75: 1111–1119.
  • Liang, J., Liu, X., Xue, H., Qiu, B., Wei, B., and Sun, K. 2015. MicroRNA-103a inhibits gastric cancer cell proliferation, migration and invasion by targeting c-Myb. Cell Prolif. 48: 78–85.
  • Lino, A. R., Abrahao, C. M., Amarante, M. P., and de Sousa Cruz, M. R. 2015. The role of the implementation of policies for the prevention of exposure to radon in Brazil—A strategy for controlling the risk of developing lung cancer. Ecancermedicalscience 9:572.
  • Liu, L., Xia, H., Luan, X., Dun, Z., Zhu, Z., Dushan, B., and Li, W. 2015. Gene expression profiling by mRNA array reveals different pattern in Chinese glioblastoma patients between Uygur and Han populations. Int. J. Clin. Exp. Med. 8: 9022–9029.
  • Liu, W., Xiao, L., Dong, C., He, M., Pan, Y., Xie, Y., Tu, W., Fu, J., and Shao, C. 2014. Long-term low-dose alpha-particle enhanced the potential of malignant transformation in human bronchial epithelial cells through MAPK/Akt pathway. Biochem. Biophys. Res. Commun. 447: 388–393.
  • Mao, G., Liu, Y., Fang, X., Liu, Y., Fang, L., Lin, L., Liu, X., and Wang, N. 2015a. Tumor-derived microRNA-494 promotes angiogenesis in non-small cell lung cancer. Angiogenesis 18: 373–382.
  • Mao, S., Shen, H., and Zhang, J. 2015b. Systemic lupus erythematosus and malignancies risk. J. Cancer Res. Clin. Oncol. 142: 253–262.
  • Modica-Napolitano, J. S, and Singh, K. K. 2000. Mitochondrial dysfunction in cancer. Mitochondrion 4: 755–762.
  • Ni, R., Huang, Y., and Wang, J. 2015. miR-98 targets ITGB3 to inhibit proliferation, migration, and invasion of non-small-cell lung cancer. Onco Targets Ther. 8: 2689–2697.
  • Oh, S. Y., Brandal, S., Kapur, R., Zhu, Z., and Takemoto, C. M. 2014. Global microRNA expression is essential for murine mast cell development in vivo. Exp. Hematol. 42: 919–923.e1.
  • Park, Y. H., Kim, D., Dai, J., and Zhang, Z. 2015. Human bronchial epithelial BEAS-2B cells, an appropriate in vitro model to study heavy metals induced carcinogenesis. Toxicol. Appl. Pharmacol. 287: 240–245.
  • Palmer, A. M., Greengrass, P. M., and Cavalla, D. 2000. The role of mitochondria in apoptosis. Drug News Perspect. 13: 398–384.
  • Ruano-Ravina, A., Aragones, N., Perez-Rios, M., Lopez-Abente, G., and Barros-Dios, J. M. 2014. Residential radon exposure and esophageal cancer. An ecological study from an area with high indoor radon concentration (Galicia, Spain). Int. J. Radiat. Biol. 90: 299–305.
  • Saki, N., Abroun, S., Soleimani, M., Hajizamani, S., Shahjahani, M., Kast, R. E., and Mortazavi, Y. 2015. Involvement of microRNA in T-Cell differentiation and malignancy. Int. J. Hematol. Oncol. Stem Cell Res. 9: 33–49.
  • Smiley, S. T., Reers, M., Mottola-Hartshorn, C., Lin, M., Chen, A., Smith, T. W., Steele, G. D., Jr., and Chen, L. B. 1991. Intracellular heterogeneity in mitochondrial membrane potentials revealed by a J-aggregate-forming lipophilic cation JC-1. Proc. Natl. Acad. Sci. USA 88: 3671–3675.
  • Sousa, S. I., Branco, P. T., Nunes, R. A., Alvim-Ferraz, M. C., and Martins F. G. 2015. Radon levels in nurseries and primary schools in braganca district-preliminary assessment. J. Toxicol. Environ. Health A 78: 805–813.
  • Takahashi, Y., Forrest, A. R., Maeno, E., Hashimoto, T., Daub, C. O., and Yasuda, J. 2009. MiR-107 and MiR-185 can induce cell cycle arrest in human non-small cell lung cancer cell lines. PLoS ONE 4: e6677.
  • Takino, T., Nakada, M., Li, Z., Yoshimoto, T., Domoto, T., and Sato, H. 2015. Tip60 regulates MT1-MMP transcription and invasion of glioblastoma cells through NF-kappaB pathway. Clin. Exp. Metastasis. 33: 45–52.
  • Tian, L., Shan, W., Zhnag, Y., Lv, X., Li, X., and Wei, C. 2015. Up-regulation of miR-21 expression predicate advanced clinicopathological features and poor prognosis in patients with non-small cell lung cancer. Pathol Oncol Res. 22: 161–167.
  • Tong, J., Qin, L., Cao, Y., Li, J., Zhang, J., Nie, J., and An Y. 2012. Environmental radon exposure and childhood leukemia. J. Toxicol. Environ. Health B 15: 332–347.
  • Vuong, W., Sartor, O., and Pal, S. K. 2014. Radium-223 in metastatic castration resistant prostate cancer. Asian J. Androl. 16: 348–353.
  • Wang, J., Chen, H., Liao, Y., Chen, N., Liu, T., Zhang, H., and Zhang, H. 2015. Expression and clinical evidence of miR-494 and PTEN in non-small cell lung cancer. Tumour Biol. 36: 6965–6972.
  • Wang, Y., Zhang, Z., Wang, H., Zhang, Y., Ji, M., Xu, H., Wang, C., Sun, Z., Gao, W., and Wang, S. L. 2015. miR-138-1* regulates aflatoxin B1-induced malignant transformation of BEAS-2B cells by targeting PDK1. Arch Toxicol. 90: 1239–1249.
  • Yang, L., Wang, Y., Lin, Z., Zhou, X., Chen, T., He, H., Huang, H., Yang, T., Jiang, Y., Xu, W., Yao, W., Liu, T., and Liu, G. 2015. Mitochondrial OGG1 protects against PM2.5-induced oxidative DNA damage in BEAS-2B cells. Exp. Mol. Pathol. 99: 365–373.
  • Yao, Q., Lin, M., Wang, Y., Lai, Y., Hu, J., Fu, T., Wang, L., Lin, S., Chen, L., and Guo, Y. 2015. Curcumin induces the apoptosis of A549 cells via oxidative stress and MAPK signaling pathways. Int J Mol Med. 36: 1118–1126.
  • Yuan, X., Wang, Y., Li, L., Zhou, W., Tian, D., Lu, C., Yu, S., Zhao, J., and Peng, S. 2015. PM induces embryonic growth retardation: Potential involvement of ROS-MAPKs-apoptosis and G0/G1 arrest pathways. Environ Toxicol. doi:10.1002/tox.22203.
  • Yun, Y., Gao, R., Yue, H., Li, G., Zhu, N., and Sang, N. 2015. Synergistic effects of particulate matter (PM10) and SO2 on human non-small cell lung cancer A549 via ROS-mediated NF-kappaB activation. J. Environ. Sci. (China) 31: 146–153.
  • Zhang, S., Wen, G., Huang, S. X., Wang, J., Tong, J., and Hei, T. K. 2013. Mitochondrial alteration in malignantly transformed human small airway epithelial cells induced by alpha-particles. Int. J. Cancer 132: 19–28.
  • Zhang, Z., Zhang, L., Yin, Z. Y., Fan, X.L., Hu, B., Wang, L. Q., and Zhang, D. 2014. miR-107 regulates cisplatin chemosensitivity of A549 non-small cell lung cancer cell line by targeting cyclin dependent kinase 8. Int. J. Clin. Exp. Pathol. 7: 7236–7241.
  • Zhou, S., Kachhap, S., Sun, W., Wu, G., Chuang, A., Poeta, L., Grumbine, L., Mithani, S. K., Chatterjee, A., Koch, W., Westra, W.H., Maitra, A., Glazer, C., Carducci, M., Sidransky, D., McFate, T., Verma, A., and Califano, J. A. 2007. Frequency and phenotypic implications of mitochondrial DNA mutations in human squamous cell cancers of the head and neck. Proc. Natl. Acad. Sci. USA 104: 7540–7545.
  • Zhu, Q., Liang, X., Dai, J., and Guan, X. 2015. Prostaglandin transporter, SLCO2A1, mediates the invasion and apoptosis of lung cancer cells via PI3K/AKT/mTOR pathway. Int. J. Clin. Exp. Pathol. 8: 9175–9181.

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