114
Views
9
CrossRef citations to date
0
Altmetric
Articles

A reduction in DNA damage in neural tissue and peripheral blood of old mice treated with caffeine

ORCID Icon, ORCID Icon, , , ORCID Icon & ORCID Icon

References

  • Arendash, G. W., Schleif, W., Rezai-zadeh, K., Acksone, K. J., Zacharia, L. C., Cracchiolo, J. R., Shippy, D., and Tan, J. 2006. Caffeine protects Alzheimer’s mice against cognitive impairment and reduces brain amyloid production. Neuroscience 142: 941–952.
  • Ascherio, A., Zhang, S. M., Hernán, M. A., Kawachi, I., Colditz, G. A. A., Speizer, F. E., and Willett, W. C. 2001. Prospective study of caffeine consumption and risk of Parkinson’s diseases in men and woman. Ann. Neurol. 50: 56–63.
  • Azam, S., Hadin Uddin, K. N., and Mumtaz, H. S. 2003. Antioxidant and prooxidant properties of caffeine, theobromine and xanthine. Med. Sci. Monit. 9: 325–330.
  • Barale, R., Chelotti, L., Davini, T., Del Ry, S., Andreassi, M. G., Ballardin, M., Bulleri, M., He, J., Baldacci, S., Di Pede, F., Gemignani, F., and Landi, S. 1998. Sister chromatid exchange and micronucleus frequency in human lymphocytes of 1,650 subjects in an Italian population: II. Contribution of sex, age, and lifestyle. Environ. Mol. Mutagen. 31: 228–242.
  • Bartsch, T., and Wulff, P. 2015. The hippocampus in aging and disease: From plasticity to vulnerability. Neuroscience 19: 1–16.
  • Beckman, K., and Ames, B. 1998. The free radical theory of aging matures. Physiol. Rev. 78: 547–581.
  • Begg, D. P., Sinclair, A. J., and Weisinger, R. S. 2012. Reductions in water and sodium intake by aged male and female rats. Nutr. Res. 32: 865–872.
  • Beghi, E., Pupillo, E., Messina, P., Giussani, G., Chiò, A., Zoccolella, S., Moglia, C., Corbo, M., Logroscino, G., and EURALS Group. 2011. Coffee and amyotrophic lateral sclerosis: A possible preventive role. Am. J. Epidemiol. 174: 1002–1008.
  • Bolognesi, C., Abbondandolo, A., Barale, R., Casalone, R., Dalprà, L., De Ferrari, M., Degrassi, F., Forni, A., Lamberti, L., Lando, C., Migliore, L., Padovani, P., Pasquini, R., Puntoni, R., Sbrana, I., Stella, M., and Bonassi, S. 1997. Age-related increase of baseline frequencies of sister chromatid exchanges, chromosome aberrations, and micronuclei in human lymphocytes. Cancer Epidemiol. Biomarkers Prev. 6: 249–256.
  • Bonassi, S., Fenech, M., Lando, C., Lin, Y. P., Ceppi, M., Chang, W. P., Holland, N., Kirsch-Volders, M., Zeiger, E., Ban, S., Barale, R., Bigatti, M. P., Bolognesi, C., Jia, C., Di Giorgio, M., Ferguson, L. R., Fucic, A., Lima, O. G., Hrelia, P., Krishnaja, A. P., Lee, T. K., Migliore, L., Mikhalevich, L., Mirkova, E., Mosesso, P., Müller, W. U., Odagiri, Y., Scarffi, M. R., Szabova, E., Vorobtsova, I., Vral, A., and Zijno, A. 2001. Human MicroNucleus project: International database comparison for results with the cytokinesis-block micronucleus assay in human lymphocytes: I. Effect of laboratory protocol, scoring criteria, and host factors on the frequency of micronuclei. Environ. Mol. Mutagen. 37: 31–45.
  • Bravo, J., Arbillaga, L., de Peña, M. P., and Cid, C. 2013. Antioxidant and genoprotective effects of spent coffee extracts in human cells. Food Chem. Toxicol. 60: 397–403.
  • Bartsch, T., and Wulff, P. 2015. The hippocampus in aging and disease: From plasticity to vulnerability. Neuroscience 19: 1–16.
  • Cabelof, D. C., Raffoul, J. J., Yanamadala, S., Ganir, C., Guo, Z., and Heydari, A. R. 2002. Attenuation of DNA polymerase beta-dependent base excision repair and increased DMS-induced mutagenicity in aged mice. Mutat. Res. 500: 135–145.
  • Childs, E., and Wit, H. 2006. Subjective, behavioral, and physiological effects of acute caffeine in light, nondependent caffeine users. Psychopharmacology (Berl) 185: 514–523.
  • Christian, M. S., and Brent, R. L. 2001. Teratogen update: Evaluation of the reproductive and developmental risks of caffeine. Teratology 64: 51–78.
  • Collins, A., Dusinska, M., Franklin, M., Somorovska, M., Petrovska, H., Duthie, S., Fillion, L., Panayiotidis, M., Raslová, K., and Vaughan, N. 1997. Comet assay in human biomonitoring studies: Reliability, validation, and applications. Environ. Mol. Mutagen. 30: 139–146.
  • Costa, M. S., Botton, P., Mioranzza, H. S., Souza, D. O., and Porciúncula, L. O. 2008. Caffeine prevents age-associated recognition memory decline and changes brain-derived neurotrophic factor and tyrosine kinase receptor (trkb) content in mice. Neuroscience 153: 1071–1078.
  • Dass, S. B., Ali, S. F., Heflich, R. H., and Casciano, D. A. 1997. Frequency of spontaneous and induced micronuclei in the peripheral blood of aging mice. Mutat. Res. 381: 105–110.
  • Dröge, W., and Schipper, H. M. 2007. Oxidative stress and aberrant signaling in aging and cognitive decline. Aging Cell 6: 361–370.
  • Fairbairn, D. W., Olive, P. L., and O’Neill, K. L. 1995. The comet assay: A comprehensive review. Mutat. Res. 339: 37–59.
  • Ferk, F., Huber, W. W., Grasl-Kraupp, B., Speer, K., Buchmann, S., Bohacek, R., Mišík, M., Edelbauer, L., and Knasmüller, S. 2014. Protective effects of coffee against induction of DNA damage and pre-neoplastic foci by aflatoxin B1. Mol. Nutr. Food Res. 58: 229–238.
  • Froy, O., and Miskin, R. 2007. The interrelations among feeding, circadian rhythms and ageing. Prog. Neurobiol. 82: 142–150.
  • George, K. C., Hebbar, S. A., Kale, S. P., and Kesavan, P. C. 1999. Caffeine protects mice against whole-body lethal dose of gamma-irradiation. J. Radiol. Prot. 19: 171–176.
  • Gorbunova, V., and Seluanov, A. 2005. Making ends meet in old age: DSB repair and aging. Mech. Ageing Dev. 126: 621–628.
  • Hashimoto, K., Takasaki, W., Sato, I., and Tsuda, S. 2007. DNA damage measured by comet assay and 8-OH-dG formation related to blood chemical analyses in aged rats. J. Toxicol. Sci. 32: 249–259.
  • Heatherley, S. V., Hayward, R. C., Seers, H. E., and Rogers, P. J. 2005. Cognitive and psychomotor performance, mood, and pressor effects of caffeine after 4, 6 and 8 h caffeine abstinence. Psychopharmacology (Berl) 178: 461–470.
  • Heuser, V. D., Andrade, V. M., Peres, A., Braga, L. M. G. M., and Chies, J. A. B. 2008. Influence of age and sex on the spontaneous DNA damage detected by micronucleus test and comet assay in mice peripheral blood cells. Cell Biol. Int. 32: 1223–1229.
  • Hodgkinson, B., Evans, D., and Wood, J. 2003. Maintaining oral hydration in older adults: A systematic review. Int. J. Nurs. Pract. 9: 19–28.
  • Kato, K., Yamamura, E., Kawanishi, M., Yagi, T., Matsuda, T., Sugiyama, A., and Uno, Y. 2011. Application of the DNA adductome approach to assess the DNA-damaging capability of in vitro micronucleus test-positive compounds. Mutat. Res. 721: 21–26.
  • Krishna, G., and Hayashi, M. 2000. In vivo rodent micronucleus assay: Protocol, conduct and data interpretation. Mutat. Res. 455: 155–166.
  • Lagouge, M., and Larsson, N. G. 2013. The role of mitochondrial DNA mutations and free radicals in disease and ageing. J. Intern. Med. 273: 529–543.
  • Leite, M. R., Wilhelm, E. A., Jesse, C. R., Brandão, R., and Nogueira, C. W. 2011. Protective effect of caffeine and a selective A2A receptor antagonist on impairment of memory and oxidative stress of aged rats. Exp. Gerontol. 46: 309–315.
  • López-Diazguerrero, N. E., Luna-López, A., Gutiérrez-Ruiz, M. C., Zentella, A., and Königsberg, M. 2005. Susceptibility of DNA to oxidative stressors in young and aging mice. Life Sci. 77: 2840–2854.
  • López-Otín, C., Blasco, M. A., Partridge, L., Serrano, M., and Kroemer, G. 2013. The hallmarks of aging. Cell 153: 1194–1217.
  • MacKenzie, T., Comi, R., Sluss, P., Keisari, R., Manwar, S., Kim, J., Larson, R., and Baron, J. A. 2007. Metabolic and hormonal effects of caffeine: Randomized, double-blind, placebo-controlled crossover trial. Metabolism 56: 1694–1698.
  • Mavournin, K. H., Blakey, D. H., Cimino, M. C., Salamone, M. F., and Heddle, J. A. 1990. The in vivo micronucleus assay in mammalian bone marrow and peripheral blood. A report of the U.S. Environmental Protection Agency Gene-Tox Program. Mutat. Res. 239: 29–80.
  • McKinley, M. J., Denton, D. A., Thomas, C. J., Woods, R. L., and Mathai, M. L. 2006. Differential effects of aging on fluid intake in response to hypovolemia, hypertonicity, and hormonal stimuli in Munich Wistar rats. Proc. Natl. Acad. Sci. USA. 103: 3450–3455.
  • Morelli, M., Frau, L., and Simola, N. 2012. Alteration in the progression of dopamine neuron degeneration: May caffeine offer new perspective? Exp. Neurol. 237: 218–222.
  • Naylor, M. D., Karlawish, J. H., Arnold, S. E., Khachaturian, A. S., Khachaturian, Z. S., Lee, V. M., Baumgart, M., Banerjee, S., Beck, C., Blennow, K., Brookmeyer, R., Brunden, K. R., Buckwalter, K. C., Comer, M., Covinsky, K., Feinberg, L. F., Frisoni, G., Green, C., Guimaraes, R. M., Gwyther, L. P., Hefti, F. F., Hutton, M., Kawas, C., Kent, D. M., Kuller, L., Langa, K. M., Mahley, R. W., Maslow, K., Masters, C. L., Meier, D. E., Neumann, P. J., Paul, S. M., Petersen, R. C., Sager, M. A., Sano, M., Schenk, D., Soares, H., Sperling, R. A., Stahl, S. M., van Deerlin, V., Stern, Y., Weir, D., Wolk, D. A., and Trojanowski, J. Q. 2012. Advancing Alzheimer’s disease diagnosis, treatment, and care: Recommendations from the Ware Invitational Summit. Alzheimers Dement. 8: 445–452.
  • Nefic, H., and Handzic, I. 2013. The effect of age, sex, and lifestyle factors on micronucleus frequency in peripheral blood lymphocytes of the Bosnian population. Mutat. Res. 753: 1–11.
  • Nisitani, S., Hosokawa, M., Sasaki, M. S., Yasuoka, K., Naiki, H., Matsushita, T., and Takeda, T. 1990. Acceleration of chromosome aberrations in senescence-accelerated strains of mice. Mutat. Res. 237: 221–228.
  • Noschang, C. G., Pettenuzzo, L. F., Toigo, E. V. P., Andreazza, A. C., Krolow, R., Fachin, F., Ávila, M. C., Arcego, D., Crema, L. M., Diehl, L. A., Gonçalvez, C. A., and Vendite Dalmaz, C. 2009. Sex-specific differences on caffeine consumption and chronic stress-induced anxiety-like behavior and DNA breaks in the hippocampus. Pharmacol. Biochem. Behav. 94: 63–69.
  • Panza, F., Solfrizzi, V., Barulli, M. R., Bonfiglio, C., Guerra, V., Osella, A., Seripa, D., Sabbà, C., Pilotto, A., and Logroscino, G. 2015. Coffee, tea, and caffeine consumption and prevention of late-life cognitive decline and dementia: a systematic review. J. Nutr. Health Aging 19: 313–328.
  • Quarta, D., Ferre, S., Solinas, M., You, Z. B., Hockemeyer, J., Popoli, P., and Goldberg, S. R. 2004. Opposite modulatory roles for adenosine A1 and A2A receptors on glutamate and dopamine release in the shell of the nucleus accumbens. Effects of chronic caffeine exposure. J. Neurochem. 88: 1151–1158.
  • Rao, K. S. 2007. DNA repair in aging rat neurons. Neuroscience 145: 1330–1340.
  • Rossi, D. J., Seita, J., Czechowicz, A., Bhattacharya, D., Bryder, D., and Weissman, I. L. 2007. Hematopoietic stem cell quiescence attenuates DNA damage response and permits DNA damage accumulation during aging. Cell Cycle 6: 2371–2376.
  • Sato, S., Taketomi, M., Nakajima, M., Kitazawa, M., Shimada, H., Itoh, S., Igarashi, M., Higashikuni, N., Sutou, S., and Sasaki, Y.F. 1995. Effect of aging on spontaneous micronucleus frequencies in peripheral blood of nine mouse strains: The results of the 7th collaborative study organized by CSGMT/JEMS.MMS. Collaborative study group for the micronucleus test. Environmental mutagen society of Japan. Mammalian mutagenesis study group. Mutat. Res. 338: 51–57.
  • Shammas, M. A. 2011. Telomeres, lifestyle, cancer, and aging. Curr. Opin. Clin. Nutr. Metab. Care 14: 28–34.
  • Singh, N. P., McCoy, M. T., Tice, R. R., and Schneider, E. L. 1988. A simple technique for quantitation of low levels of DNA damage in individual cells. Exp. Cell Res. 175: 184–191.
  • Swai, U., and Rao, K. S. 2011. Study of DNA damage via the comet assay and base excision repair activities in rat brain neurons and astrocytes during aging. Mech. Ageing Dev. 132: 374–381.
  • Thunhorst, R. L., and Johnson, A. K. 2003. Thirst and salt appetite responses in young and old Brown Norway rats. Am. J. Physiol. Regul. Integr. Comp. Physiol. 284: 17–27.
  • Tice, R. R., Agurell, E., Anderson, D., Burlinson, B., Hartmann, A., Kobayashi, H., Miyamae, Y., Rojas, E., Ryu, J. C., and Sasaki, Y. F. 2000. Single cell gel/comet assay: Guidelines for in vitro and in vivo genetic toxicology testing. Environ. Mol. Mutagen. 35: 206–221.
  • Vijg, J. 2000. Somatic mutations and aging: A re-evaluation. Mutat. Res. 447: 117–135.
  • Vijg, J., and Suh, Y. 2013. Genome instability and aging. Annu. Ver. Physiol. 75: 645–668.
  • Wang, L., Shen, L., Ping, J., Zhang, L., Liu, Z., Wu, Y., Liu, Y., Huang, H., Chen, L., and Wang, H. 2014. Intrauterine metabolic programming alteration increased susceptibility to non-alcoholic adult fatty liver disease in prenatal caffeine-exposed rat offspring. Toxicol. Lett. 224: 311–318.
  • Warburton, D. M., Bersellini, E., and Sweeney, E. 2001. An evaluation of a caffeinated taurine drink on mood, memory and information processing in healthy volunteers without caffeine abstinence. Psychopharmacology (Berl) 158: 322–328.
  • Wentz, C. T., and Magavi, S. S. 2009. Caffeine alters proliferation of neuronal precursors in the adult hippocampus. Neuropharmacology 56: 994–1000.
  • Xi, H., Li, C., Ren, F., Zhang, H., and Zhang, L. 2013. Telomere, aging and age-related diseases. Aging Clin. Exp. Res. 25: 139–146.
  • Yoshimura, H. 2005. The potential of caffeine for functional modification from cortical synapses to neuron networks in the brain. Curr. Neuropharmacol. 3: 309–316.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.