Non-cancer, cancer, and dermal sensitization risk assessment of heavy metals in cosmetics

References

• Adepoju-Bello, A. A., O. O. Oguntibeju, R. A. Adebisi, N. Okpala, and H. A. B. Coker. 2012. Evaluation of the concentration of toxic metals in cosmetic products in Nigeria. African Journal Biotechnology 11:16360–64.
   Google Scholar
• Alqadami, A. A., M. A. Abdalla, Z. A. Alothman, and K. Omer. 2013. Application of solid phase extraction on multi walled carbon nanotubes of some heavy metal ions to analysis of skin whitening cosmetics using ICP-AES. International Journal Environment Researcher Public Health 10:361–74. doi:10.3390/ijerph10010361.
   PubMed Web of Science ®Google Scholar
• Al-Saleh, I., and I. Al-Doush. 1997. Mercury content in skin lightening creams and potential health hazards to the health of Saudi women. Journal Toxicogical Environment Health 51:123–30. doi:10.1080/00984109708984016.
   PubMed Web of Science ®Google Scholar
• Al-Saleh, I., and S. Al-Enazi. 2011. Trace metals in lipsticks. Toxicogical Environment Chemical 93:1149–65. doi:10.1080/02772248.2011.582040.
   Web of Science ®Google Scholar
• APHA (American Public Health Assoication). 1992. Standard methods for the examination of water and wastewater analysis, 18th ed. Washington, DC: APHA.
   Google Scholar
• Api, A. M., D. A. Basketter, P. A. Cadby, M. F. Cano, G. Ellis, G. F. Gerberick, P. Griem, P. M. McNamee, C. A. Ryan, and R. Safford. 2008. Dermal sensitization quantitative risk assessment (QRA) for fragrance ingredients. Regulatory Toxicology and Pharmacology 52:3–23. doi:10.1016/j.yrtph.2007.10.008.
   PubMed Web of Science ®Google Scholar
• Api, A. M., and M. Vey. 2008. Implementation of the dermal sensitization quantitative risk assessment (QRA) for fragrance ingredients. Regulatory Toxicology and Pharmacology 52:53–61. doi:10.1016/j.yrtph.2008.05.011.
   PubMed Web of Science ®Google Scholar
• ATSDR (Agency for Toxic Substances and Disease Registry). 1992. Agency for toxic substances and disease registry. toxicological profile for antimony. Atlanta, USA: U.S. Department of Health and Human Services, Public Health Service.
   Google Scholar
• ATSDR (Agency for Toxic Substances and Disease Registry). 1993. Toxicological profile for cadmium, USA. Department of Health &Human Services; Centers for Disease Control and Prevention; Agency for Toxic Substances and Disease Registry, Published Report.
   Google Scholar
• ATSDR (Agency for Toxic Substances and Disease Registry). 2007. Toxicological profile for lead. Atlanta, USA: U.S. Department of Health and Human Services, Public Health Service.
   Google Scholar
• ATSDR (Agency for Toxic Substances and Disease Registry). 2008. Toxicological profile for chromium. Atlanta, USA: U.S. Department of Health and Human Services, Public Health Service.
   Google Scholar
• Ayenimo, J. G., A. M. Yusuf, A. S. Adekunle, and O. W. Makinde. 2010. Heavy metal exposure from personal care products. Bulletin Environment Contamination Toxicogical 84:8–14. doi:10.1007/s00128-009-9867-5.
   PubMed Web of Science ®Google Scholar
• Barbosa, F., Jr. 2017. Toxicology of metals and metalloids: Promising issues for future studies in environmental health and toxicology. Journal Toxicogical Environment Heath A 80:137–44. doi:10.1080/15287394.2016.1259475.
   PubMed Web of Science ®Google Scholar
• Barlow, S., A. G. Renwick, J. Kleiner, J. W. Bridges, L. Busk, E. Dybing, L. Edler, G. Eisenbrand, J. Fink-Gremmels, A. Knaap, R. Kroes, D. Liem, D. J. Müller, S. Page, V. Rolland, J. Schlatter, A. Tritscher, W. Tueting, and G. Würtzen. 2006. Risk assessment of substances that are both genotoxic and carcinogenic - Report of an international conference organized by EFSA and WHO with support of ILSI Europe. Food Chemical Toxicogical 44:1636–50. doi:10.1016/j.fct.2006.06.020.
   PubMed Web of Science ®Google Scholar
• Basketter, D. A., K. E. Andersen, C. Liden, H. Van Loveren, A. Boman, I. Kimber, K. Alanko, and E. Berggren. 2005. Evaluation of the skin sensitizing potency of chemicals by using the existing methods and considerations of relevance for elicitation. Contact Dermatitis 52:39–43. doi:10.1111/cod.2005.52.issue-1.
   PubMed Web of Science ®Google Scholar
• Basketter, D. A., C. J. Clapp, B. J. Safford, I. R. Jowsey, P. McNamee, C. A. Ryan, and F. G. Gerberick. 2008. Preservatives and skin sensitization quantitative risk assessment. Dermatitis 19:20–27.
   PubMed Web of Science ®Google Scholar
• Basketter, D. A., L. J. Lea, A. Dickens, D. Briggs, I. Pate, R. J. Dearman, and I. Kimber. 1999. A comparison of statistical approaches to the derivation of EC3 values from local lymph node assay dose responses. Journal Applications Toxicogical 19:261–66. doi:10.1002/(ISSN)1099-1263.
   PubMed Web of Science ®Google Scholar
• Basketter, D. A., E. W. Scholes, and I. Kimber. 1994. The performance of the local lymph node assay with chemicals identified as contact allergens in the human maximization test. Food and Chemical Toxicology 32:543–47. doi:10.1016/0278-6915(94)90112-0.
   PubMed Web of Science ®Google Scholar
• Bellinger, D. C. 2008. Very low lead exposure and children’s neurodevelopment. Current Opinion in Pediatrics 20:172–77. doi:10.1097/MOP.0b013e3282f4f97b.
   PubMed Web of Science ®Google Scholar
• Bernstam, L., and J. Nriagu. 2000. Molecular aspects of arsenic stress. Journal of Toxicology and Environmental Health, Part B 3:293–322. doi:10.1080/109374000436355.
   PubMed Web of Science ®Google Scholar
• BIS (Departments for business innovation and skills). 2010. A guide to the cosmetic products (Safety) regulations 2008. https://www.gov.uk/government/uploads/system/uploads/attachment_data/file/39334/10-761guide-to-cpsr.pdf.
   Google Scholar
• Bocca, B., G. Forte, F. Petrucci, and A. Cristaudo. 2007. Levels of nickel and other potentially allergenic metals in Ni-tested commercial body creams. Journal Pharmaceut Biomedical 44:1197–202. doi:10.1016/j.jpba.2007.04.031.
   PubMed Web of Science ®Google Scholar
• Branco, V., S. Caito, M. Farina, J. Teixeira da Rocha, M. Aschner, and C. Carvalho. 2017. Biomarkers of mercury toxicity: Past, present, and future trends. Journal of Toxicology and Environmental Health, Part B 20:119–54. doi:10.1080/10937404.2017.1289834.
   PubMed Web of Science ®Google Scholar
• Brandao, J. D. O., O. J. Okonkwo, M. Sehkula, and R. M. Raseleka. 2012. Concentrations of lead in cosmetics commonly used in South Africa. Toxicogical Environment Chemical 94:70–77. doi:10.1080/02772248.2011.633911.
   Web of Science ®Google Scholar
• Bress, W. C., and J. H. Bidanset. 1991. Percutaneous in vivo and in vitro absorption of lead. Veterinary and Human Toxicology 33:212–14.
   PubMedGoogle Scholar
• Cal/EPA (California Environmental Protection Agency). 2001a. Public health goal for sluminum in drinking water. http://www.oehha.ca.gov/water/phg/pdf/Aluminumf.pdf.
   Google Scholar
• Cal/EPA (California Environmental Protection Agency). 2001b. Public health goals for chemicals in drinking water: Nickel. http://www.oehha.ca.gov/water/phg/pdf/nickel82001.pdf
   Google Scholar
• Cal/EPA (California Environmental Protection Agency). 2006. Public health goals for chemicals in drinking water: Cadmium. http://oehha.ca.gov/water/phg/pdf/122206cadmiumphg.pdf.
   Google Scholar
• Cal/EPA (California Environmental Protection Agency). 2008a. Appendix D. Individual scute, 8-Hour, and chronic reference exposure level summaries. http://www.oehha.ca.gov/air/hot_spots/2008/AppendixD1_final.pdf#page=170.
   Google Scholar
• Cal/EPA (California Environmental Protection Agency). 2008b. Public health goals for chemicals in drinking water: Copper. http://www.oehha.ca.gov/water/phg/Pdf/CopperPHG020808.pdf.
   Google Scholar
• Cal/EPA (California Environmental Protection Agency). 2009. Public health goals for chemicals in drinking water: Lead. http://www.oehha.ca.gov/water/phg/pdf/LeadfinalPHG042409.pdf.
   Google Scholar
• CDC (Centers for Disease Control and Prevention). 2003. Second national report on human exposure to environmental chemicals. http://www.cdc.gov/exposurereport/2nd/.
   Google Scholar
• Chauhan, A. S., R. Bhadauria, A. K. Singh, S. S. Lodhi, D. K. Chaturvedi, and V. S. Tomari. 2010. Determination of lead and cadmium in cosmetics products. Journal Chemical Pharmaceutical Researcher 2:92–97.
   Google Scholar
• Christensen, J. M. 1995. Human exposure to toxic metals – Factors influencing interpretation of biomonitoring results. Science of the Total Environment 166:89–135. doi:10.1016/0048-9697(95)04478-J.
   PubMed Web of Science ®Google Scholar
• COC (Committee on Carcinogenicity of chemicals in food. consumer products and the environment). 2007. Annual report. http://cot.food.gov.uk/sites/default/files/cot/cocsection07.pdf.
   Google Scholar
• Contado, C., and A. Pagnoni. 2012. A new strategy for pressed powder eye shadow analysis: Allergenic metal ion content and particle size distribution. The Science of the Total Environment 432:173–79. doi:10.1016/j.scitotenv.2012.05.092.
   PubMed Web of Science ®Google Scholar
• Corazza, M., F. Baldo, A. Pagnoni, R. Miscioscia, and A. Virgili. 2009. Measurement of nickel, cobalt and chromium in toy makeup by atomic absorption spectroscopy. Acta Dermatological Venereology 89:130–33.
   PubMed Web of Science ®Google Scholar
• CPHR (Centre for Public Health Research). 2011. Report for a survey of low cost cosmetics (lipstick) for the Ministry of Health. Wellington, New Zealand: Massey University.
   Google Scholar
• CSC (Campaign for Safe Cosmetics). 2009. No more toxic tub: Getting contaminants out of children’s bath & personal care products. http://www.safecosmetics.org/article.php?id=223.
   Google Scholar
• da Silva, R. F., C. D. S. Borges, C. de Almeida Lamas, V. H. A. Cagnon, and W. De Grava Kempinas. 2017. Arsenic trioxide exposure impairs testicular morphology in adult male mice and consequent fetus viability. Journal Toxicogical Environment Health A 80:1166–79. doi:10.1080/15287394.2017.1376405.
   PubMed Web of Science ®Google Scholar
• DEPA (The Danish Environmental Protection Agency). 2008. Nickel chloride CAS-No.: 7718- 54-9risk assessment. http://eng.mst.dk/media/mst/67160/Ni_chloride_EU_RAR_HH_March_2008_final%20draft.pdf.
   Google Scholar
• Devóz, P. P., W. R. Gomes, M. L. De Araújo, D. L. Ribeiro, T. Pedron, L. M. Greggi Antunes, B. L. Batista, F. Barbosa, Jr., and G. R. M. Barcelos. 2017. Lead (Pb) exposure induces disturbances in epigenetic status in workers exposed to this metal. Journal Toxicogical Environment Health A 80:1098–105. doi:10.1080/15287394.2017.1357364.
   PubMed Web of Science ®Google Scholar
• EC (European Commission). 2000. Meeting of the commission working group on the classification and labelling of dangerous substances. https://www.google.co.kr/url?sa=t&rct=j&q=&esrc=s&source=web&cd=1&ved=0CB4QFjAA&url=http%3A%2F%2Fapps.kemi.se%2Fhclass%2FDocumentDownload.aspx%3FDocId%3D924586&ei=IhwgVJTsMIrz8QWe8ILoAw&usg=AFQjCNFjl674FAQKJSaDZB9fjWG16Qq7RA&bvm=bv.75775273,d.dGc&cad=rjt.
   Google Scholar
• EC (European Communities). 2008. European commission. Opinion of the TC NES on the human health part of industry voluntary risk assessments on copper and copper compounds. https://echa.europa.eu/documents/10162/13630/tcnes_opinion_hh_en.doc/2f93f5a0-1480-4742-87d0-046f31ebd31d+&cd=1&hl=ko&ct=clnk&gl=kr.
   Google Scholar
• EDC (Environmental Defense Canada). 2011. Heavy metal hazard. The health risks of hidden heavy metals in face makeup. Toronto, Canada: Environmental Defense. http://environmentaldefence.ca/sites/default/files/report_files/HeavyMetalHazard%20FINAL.pdf.
   Google Scholar
• EFSA (European Food Safety Authority). 2005. Opinion of the scientific committee on a request from EFSA related to a harmonized approach for risk assessment of substances which are both genotoxic and carcinogenic. The EFSA Journal 282:1–31. http://www.efsa.europa.eu/en/efsajournal/doc/282.pdf.
   Google Scholar
• EFSA (European Food Safety Authority). 2010. Lead in food – Scientific opinion of the panel on contaminants in the food chain. EFSA Journal 7:1351.
   Google Scholar
• El-Shazly, E. A. A., A.-Z. ShF., F. H. El-Sweify, and G. D. Kanias. 2004. Simultaneous multi element determination in some cosmetic samples of different origins using neutron activation analysis. Radiochimica Acta 92:111–17. doi:10.1524/ract.92.2.111.27466.
   Web of Science ®Google Scholar
• EU (European Union). 2009a. The rules governing cosmetic products in the European Union, Volume 1, cosmetics legislation 1999 edition, European Commission, enterprise directorate-general, pharmaceuticals and cosmetics. http://www.leffingwell.com/cosmetics/vol_1en.pdf.
   Google Scholar
• EU (European Union). 2009b. European Union. Regulation (EC) No 1223/2009 of the European Parliament and of the Council of 30 November 2009 on cosmetic products. Official Journal L342/59 - L342/209. December 22, 2009.
   Google Scholar
• EURAR (European Union risk assessment report). 2008. European Union risk assessment report [draft]. Diantimony trioxide CAS No. 1309- 64-4[Internet]. Luxembourg: Office for official publications of the European Communities. Accessed February 7, 2009. http://ecb.jrc.ec.europa.eu/DOCUMENTS/ExistingChemicals/RISK_ASSESSMENT/REPORT/datreport415.pdf.
   Google Scholar
• EWG (Environmental Working Group). 2007. Impurities of concern in personal care products. 2007. http://www.ewg.org/skindeep/2007/02/04/impurities-of-concern-in-personal-care-products.
   Google Scholar
• Fischer, L. A., T. Menne, and J. D. Johansen. 2005. Experimental nickel elicitation thresholds – A review focusing on occluded nickel exposure. Contact Dermatitis 52:57–64. doi:10.1111/cod.2005.52.issue-2.
   PubMed Web of Science ®Google Scholar
• Fischer, T. 2003. Cobalt chloride. In Management of positive patch test reactions, eds. J. E. Wahlberg, P. Elsner, L. Kanerva, and H. I. Maibach, 3–6. Heidelberg: Springer.
   Google Scholar
• Flarend, R., T. Bin, D. Elmore, and S. L. Hem. 2001. A preliminary study of dermal absorption of aluminum from antiperspirants usingaluminium-26. Food and Chemical Toxicology 39:163–68. doi:10.1016/S0278-6915(00)00118-6.
   PubMed Web of Science ®Google Scholar
• Gamer, A. O., E. Leibold, and B. Van-Ravenzwaay. 2006. The in vitro absorption of micron zinc oxide 40 and titanium dioxide through porcine skin. Toxicogical In Vitro 20:301–07. doi:10.1016/j.tiv.2005.08.008.
   PubMed Web of Science ®Google Scholar
• Gerberick, G. F., M. K. Robinson, C. A. Ryan, R. J. Dearman, I. Kimber, D. A. Basketter, Z. Wright, and J. G. Marks. 2001. Contact allergenic potency: Correlation of human and local lymph node assay data. American Journal of Contact Dermatitis 12:156–61.
   PubMedGoogle Scholar
• Godt, J., F. Scheidig, C. Grosse-Siestrup, V. Esche, P. Brandenburg, A. Reich, and D. A. Groneberg. 2006. The toxicity of cadmium and resulting hazards for human health. Journal of Occupational Medicine and Toxicology 10:1–22.
   Google Scholar
• Goh, C. L., S. K. Ng, and S. F. Kwok. 1989. Allergic contact dermatitis from nickel in eye shadows. Contact Dermatitis 20:380–81. doi:10.1111/j.1600-0536.1989.tb03179.x.
   PubMed Web of Science ®Google Scholar
• Gondal, M. A., Z. S. Seddigi, M. M. Nasr, and B. Gondal. 2010. Spectroscopic detection of health hazardous contaminants in lipstick using laser induced breakdown spectroscopy. Journal Hazardous Materials 175:726–32. doi:10.1016/j.jhazmat.2009.10.069.
   PubMed Web of Science ®Google Scholar
• Grosser, Z., L. Davidowski, and L. Thompson. 2011. The determination of metals in cosmetics. PerkinElmer Applications Note 1–6. http://www.perkinelmer.com.cn/CMSResources/Images/44-132749APP_MetalsinCosmeticsELANICP-MS.pdf
   Google Scholar
• Gunduz, S., and S. Akman. 2013. Investigation of lead contents in lipsticks by solid sampling high resolution continuum source electro thermal atomic absorption spectrometry. Regulatory Toxicology and Pharmacology 65:34–37. doi:10.1016/j.yrtph.2012.10.009.
   PubMed Web of Science ®Google Scholar
• Guy, R., J. J. Hostynek, R. S. Hinz, and C. R. Lorence. 1999. Metals and the skin: Topical, effects and systemic absorption, 3rd ed. New York: CRC Press.
   Google Scholar
• HC-SC (Health Canada-Sante Canada). 2013. Guidance on heavy metal impurities in cosmetics. http://www.hc-sc.gc.ca/cps-spc/pubs/indust/heavy_metalsmetaux_lourds/index-eng.php.
   Google Scholar
• Hébert, C. D., M. R. Elwell, G. S. Travios, C. J. Fitz, and J. R. Bucher. 1993. Subchronic toxicity of cupric sulfate administered in drinking water and feed to rats and mice. Fundamentals Applications Toxicogical 21:461–75. doi:10.1006/faat.1993.1122.
   PubMedGoogle Scholar
• Hepp, N. 2012. Determination of total lead in 400 lipsticks on the U.S. market using a validated microwave-assisted digestion, inductively coupled plasma-mass spectrometry method. Journal Cosmetic Sciences 63:159–76.
   PubMed Web of Science ®Google Scholar
• Hepp, N. M., W. R. Mindak, and J. Cheng. 2009. Determination of total lead in lipstick: Development and validation of a microwave-assisted digestion, inductively coupled plasma mass spectrometric method. Journal Cosmetic Sciences 60:405–14.
   PubMed Web of Science ®Google Scholar
• HERAG (Health Risk Assessment Guidance for Metals). 2007. Assessment of occupational dermal exposure and dermal absorption for metals and inorganic metal compounds. http://www.metalsriskassessment.org.
   Google Scholar
• Hooper, P. L., L. Visconti, P. J. Garry, and G. E. Johnson. 1980. Zinc lowers high density lipoprotein-cholesterol levels. Journal of the American Medical Association 244:1960–61. doi:10.1001/jama.1980.03310170058030.
   PubMed Web of Science ®Google Scholar
• IRIS (Integrated Risk Information System). 1998a. Toxicological review of hexavalent chromium (CAS No. 18540-29-9). In support of summary information on the Integrated Risk Information System (IRIS), Agency, E.-E. P., Published Report. http://www.epa.gov/iris/subst/index.html.
   Google Scholar
• IRIS (Integrated Risk Information System). 1998b. Chromium(III), insoluble salts; CASRN 16065-83-1. https://cfpub.epa.gov/ncea/iris/iris_documents/documents/subst/0028_summary.pdf.
   Google Scholar
• IRIS (Integrated Risk Information System). 2005. Zinc and compounds. Integrated Risk Information System, DC: U.S. Environmental Protection Agency, Place, Published Report, Number. http://www.epa.gov/iris/subst/index.html.
   Google Scholar
• IRIS (Integrated Risk Information System). 2007. Chromium. Integrated Risk Information System, DC: U.S. Environmental Protection Agency, Place, Published Report, Number. http://www.epa.gov/iris/subst/index.html.
   Google Scholar
• IRIS (Integrated Risk Information System). 2009. Thallium and compounds. Integrated Risk Information System, DC: U.S. Environmental Protection Agency, Place, Published Report, Number. http://www.epa.gov/iris/subst/index.html.
   Google Scholar
• IRIS (Integrated Risk Information System). 2016a. Manganese. Integrated Risk Information System, DC: U.S. Environmental Protection Agency, Place, Published Report, Number. http://www.epa.gov/iris/subst/index.html.
   Google Scholar
• IRIS (Integrated Risk Information System). 2016b. Nickel, soluble salts; CASRN various. https://cfpub.epa.gov/ncea/iris/iris_documents/documents/subst/0271_summary.pdf#nameddest=rfd.
   Google Scholar
• IRIS (Integrated Risk Information System). 2016c. Copper. Integrated Risk Information System, DC: U.S. Environmental Protection Agency, Place, Published Report, Number. http://www.epa.gov/iris/subst/index.html.
   Google Scholar
• IRIS (Integrated Risk Information System). 2016d. Arsenic, inorganic; CASRN 7440-38-2. https://cfpub.epa.gov/ncea/iris/iris_documents/documents/subst/0278_summary.pdf.
   Google Scholar
• IRIS (Integrated Risk Information System). 2016e. Mercury. Integrated Risk Information System, DC: U.S. Environmental Protection Agency, Place, Published Report, Number. http://www.epa.gov/iris/subst/index.html.
   Google Scholar
• IRIS (Integrated Risk Information System). 2016f. Antimony. Integrated Risk Information System, DC: U.S. Environmental Protection Agency, Place, Published Report, Number. http://www.epa.gov/iris/subst/index.html.
   Google Scholar
• Iyer, V. J., G. Banerjee, C. B. Govindram, V. Kamath, S. Shinde, A. Gaikwad, H. R. Jeraiani, G. Raman, and K. M. Cherian. 2002. Role of different valence states of chromium in the elicitation of allergic contact dermatitis. Contact Dermatitis 47:357–60. doi:10.1034/j.1600-0536.2002.470608.x.
   PubMed Web of Science ®Google Scholar
• Jager, C., and U. Jappe. 2005. Contact dermatitis to permanent make up: Manifestation of a preexisting nickel allergy. Journal Deuutschen Dermatological Gesellshaft (JDDS) 3:527–29. doi:10.1111/j.1610-0387.2005.05717.x.
   PubMedGoogle Scholar
• JECFA (Joint Food and Agriculture Organization/World Health Organization Expert Committee on Food Additives). 2010. Summary and conclusions of the seventy-second meeting of the Joint FAO/WHO Expert Committee on Food Additives, Rome, 16–25 February 2010. Rome, Food and Agriculture Organization of the United Nations; Geneva, World Health Organization (JECFA/72/SC). http://www.who.int/foodsafety/chem/summary72_rev.pdf.
   Google Scholar
• JMOE (Ministry of the Environment, Government of Japan). 2010. Cobalt and its compounds. https://www.env.go.jp/en/chemi/chemicals/profile_erac/profile11/pf1-09.pdf.
   Google Scholar
• Kang, B., B. M. Lee, and H. S. Shin. 2014. Determination of polycyclic aromatic hydrocarbon(PAH) content and risk assessment from edible oils in Korea. Journal Toxicogical Environment Health A 77:1359–71. doi:10.1080/15287394.2014.951593.
   PubMed Web of Science ®Google Scholar
• Karlberg, A. T., C. Liden, and E. Ehrin. 1991. Colophony in mascara as a cause of eyelid dermatitis. Chemical analyses and patch testing. Acta Dermatological Venereology 71:445–47.
   PubMed Web of Science ®Google Scholar
• Kim, K. B., Y. W. Kim, S. K. Lim, T. H. Roh, D. Y. Bang, S. M. Choi, D. S. Lim, Y. J. Kim, S. H. Baek, M. K. Kim, H. S. Seo, M. H. Kim, H. S. Kim, J. Y. Lee, S. Kacew, and B. M. Lee. 2017. Risk assessment of zinc oxide, a cosmetic ingredient used as a UV filter of sunscreens. Journal Toxicogical Environment Health B 20:155–82. doi:10.1080/10937404.2017.1290516.
   PubMed Web of Science ®Google Scholar
• Kim, Y. W., M. J. Kim, B. Y. Chung, D. Y. Bang, S. K. Lim, S. M. Choi, D. S. Lim, M. C. Cho, K. Yoon, H. S. Kim, K. B. Kim, Y. S. Kim, S. J. Kwack, and B. M. Lee. 2013. Safety evaluation and risk assessment of d-Limonene. Journal of Toxicology and Environmental Health, Part B 16:17–38. doi:10.1080/10937404.2013.769418.
   PubMed Web of Science ®Google Scholar
• Kimber, I., G. F. Gerberick, and D. A. Basketter. 1999. Thresholds in contact sensitization: Theoretical and practical considerations. Food and Chemical Toxicology 37:553–60. doi:10.1016/S0278-6915(99)00048-4.
   PubMed Web of Science ®Google Scholar
• Kleiman, N. J., A. M. Quinn, K. G. Fields, V. Slavkovich, and J. H. Graziano. 2016. Arsenite accumulation in the mouse eye. Journal Toxicogical Environment Health A 79:339–41. doi:10.1080/15287394.2016.1151392.
   PubMed Web of Science ®Google Scholar
• Koo, H. Y. 2013. Study on the intake amount of lipstick and lip-gloss and content monitoring. Journal Korea Social Cosmetic 19:54–61.
   Google Scholar
• Lavilla, I., N. Cabaleiro, M. Costas, I. De La Calle, and C. Bendicho. 2009. Ultra sound assisted emulsification of cosmetic samples prior to elemental analysis by different atomic spectrometric techniques. Talanta 80:109–16. doi:10.1016/j.talanta.2009.06.036.
   PubMed Web of Science ®Google Scholar
• Lee, M., J. H. Hwang, and K. M. Lim. 2017. Alternatives to in vivo Draize rabbit eye and skin irritation tests with a focus on 3D reconstructed human cornea-like epithelium and epidermis models. Toxicogical Researcher 33:191–203. doi:10.5487/TR.2017.33.3.191.
   PubMed Web of Science ®Google Scholar
• Lim, H., J. A. Lim, J. H. Choi, H. J. Kwon, M. Ha, H. Kim, and J. D. Park. 2016. Associations of low environmental exposure to multiple metals with renal tubular impairment in Korean adults. Toxicogical Researcher 32:57–64. doi:10.5487/TR.2016.32.1.057.
   PubMed Web of Science ®Google Scholar
• Liu, S., K. Hammond, and A. Rojas-Cheatham. 2013. Concentrations and potential health risks of metals in lip products. Environmental Health Perspectives 121:705–10. doi:10.1289/ehp.1205518.
   PubMed Web of Science ®Google Scholar
• Loh, M. M., J. I. Levy, J. D. Spengler, E. A. Houseman, and D. H. Bennett. 2007. Ranking cancer risks of organic hazardous air pollutants in the United States. Environmental Health Perspectives 115:1160–68. doi:10.1289/ehp.9884.
   PubMed Web of Science ®Google Scholar
• Loretz, L. J., A. M. Api, L. Babcock, L. M. Barraj, J. Burdick, K. C. Cater, G. Jarrett, S. Mann, Y. H. Pan, T. A. Re, K. J. Renskers, and C. G. Scrafford. 2008. Exposure data for cosmetic products: Facial cleanser, hair conditioner, and eye shadow. Food and Chemical Toxicology 46:1516–24. doi:10.1016/j.fct.2007.12.011.
   PubMed Web of Science ®Google Scholar
• Loretz, L. J., A. M. Api, L. M. Barraj, J. Burdick, D. A. Davis, W. Dressler, E. Gilberti, G. Jarret, S. Mann, L. Pan, T. Re, K. Renskers, C. Scrafford, and S. Vater. 2006. Exposure data for personal care products: Hairspray, spray perfume, liquid foundation, shampoo, body wash, and solid antiperspirant. Food and Chemical Toxicology 44:2008–18. doi:10.1016/j.fct.2006.06.029.
   PubMed Web of Science ®Google Scholar
• Loretz, L. J., A. M. Api, L. M. Barraj, J. Burdick, W. E. Dressler, S. D. Gettings, H. Han-Hsu, Y. H. L. Pan, T. A. Re, K. J. Renskers, A. Rothenstein, C. G. Scrafford, and C. Sewall. 2005. Exposure data for cosmetic products: Lipstick, body lotion, and face cream. Food and Chemical Toxicology 43:279–91. doi:10.1016/j.fct.2004.09.016.
   PubMed Web of Science ®Google Scholar
• Ly, S. Y., C. H. Lee, and J. M. Koo. 2017. Detection of toxic heavy metal, Co(II) trace via voltammetrywith semiconductor microelectrodes. Toxicogical Researcher 33:135–40. doi:10.5487/TR.2017.33.2.135.
   PubMed Web of Science ®Google Scholar
• Lynch, B. S., C. C. Capen, E. R. Nestmann, G. Veenstra, and J. A. Deyo. 1999. Review of subchronic/chronic toxicity of antimony potassium tartrate. Regulatory Toxicology and Pharmacology 30:9–17. doi:10.1006/rtph.1999.1312.
   PubMed Web of Science ®Google Scholar
• Macedo-Júnior, S. J., M. Luiz-Cerutti, D. B. Nascimento, M. Farina, A. R. Soares Santos, and A. H. de Azevedo Maia. 2017. Methylmercury exposure for 14 days (short-term) produces behavioral and biochemical changes in mouse cerebellum, liver, and serum. Journal Toxicogical Environment Health A 80:1145–55. doi:10.1080/15287394.2017.1357324.
   PubMed Web of Science ®Google Scholar
• Marinovich, M., M. S. Boraso, E. Testai, and C. L. Galli. 2014. Metals in cosmetics: An a posteriori safety evaluation. Regulatory Toxicology and Pharmacology 69:416–24. doi:10.1016/j.yrtph.2014.05.005.
   PubMed Web of Science ®Google Scholar
• McKelvey, W., N. Jeffery, N. Clark, D. Kass, and P. J. Parsons. 2011. Population-based inorganic mercury biomonitoring and the identification of skin care products as a source of exposure in New York City. Environmental Health Perspectives 119:203–09. doi:10.1289/ehp.1002396.
   PubMed Web of Science ®Google Scholar
• MDH (Minnesota Department of Health). 2015. Health based guidance for water health risk assessment unit, Environmental Health Division. Toxicological summary for: Cadmium. http://www.health.state.mn.us/divs/eh/risk/guidance/gw/cadmium.pdf.
   Google Scholar
• MFDS (Ministry of Food and Drug Safety). 2015. Regulations on the Safety Standards, etc. of Cosmetics. http://www.mfds.go.kr/eng/eng/index.do?nMenuCode=167&searchKeyCode=172&page=1&mode=view&boardSeq=69993.
   Google Scholar
• Murphy, T., D. G. Slotton, K. Irvine, K. Sukontason, and C. R. Goldman. 2009. Mercury contamination of skin whiteners in Cambodia. Human Ecology Risk Assessment 15:1286–12303. doi:10.1080/10807030903306877.
   Web of Science ®Google Scholar
• Mustapha, M. K. 2017. Dynamics of hexavalent chromium in four types of aquaculture ponds and its effects on the morphology and behavior of cultured Clarias gariepinus (Burchell 1822). Toxicogical Researcher 33:119–24. doi:10.5487/TR.2017.33.2.119.
   PubMed Web of Science ®Google Scholar
• Nnorom, I. C., J. C. Igwe, and C. G. Oji-Nnorom. 2005. Trace metal contents of facial (make-up) cosmetics commonly used in Nigeria. African Journal Biotechnology 4:1133–38.
   Web of Science ®Google Scholar
• Nohynek, G. J., E. Antignac, T. Re, and H. Toutain. 2010. Safety assessment of personal care products/cosmetics and their ingredients. Toxicology and Applied Pharmacology 243:239–59. doi:10.1016/j.taap.2009.12.001.
   PubMed Web of Science ®Google Scholar
• NTP (National Toxicology Program). 2008. NTP technical report on the toxicology and carcinogenesis studies of sodium dichromate dihydrate (CAS No. 7789-12-0) in F344/N rats and B6C3F1 mice (drinking water studies). Washington, DC: National Toxicology Program. NTP TR 546. Accessed August 13, 2008 http://ntp.niehs.nih.gov/files/546_web_FINAL.pdf.
   Google Scholar
• OECD. 2004. Iron dichloride. SIDS initial assessment report for iron dichloride. http://www.inchem.org/documents/sids/sids/7758943.pdf.
   Google Scholar
• OECD. 2008. Nickel & nickel compounds. SIDS initial assessment profile. http://webnet.oecd.org/Hpv/UI/handler.axd?id=9ce00cf2-296e-459f-a92e-aec0c9771a7b
   Google Scholar
• OEHHA (Office of Environmental Health Hazard Assessment). 1999. Technical support document for using cancer potency factors, OEHHA. Accessed November 2. http://www.oehha.ca.gov/scientific/haca2.htm,downloaded.
   Google Scholar
• Omolaoye, J. A., A. Uzairu, and C. E. Gimba. 2010. Heavy metal assessment of some eye shadow products imported into Nigeria from China. Archives Applications Sciences Researcher 2:76–84.
   Google Scholar
• Onwordi, C. T., C. O. Orizu, A. D. Wusu, and I. A. Ogunwande. 2011. Potentially toxic metals exposure from body creams sold in Lagos. Nigeria Researcher 3:30–37.
   Google Scholar
• Oyedeji, F. O., G. O. Hassan, and B. B. Adeleke. 2011. Hydroquinone and heavy metals levels in cosmetics marketed in Nigeria. Trends Applied Sciences Researcher 6:622–39. doi:10.3923/tasr.2011.622.639.
   Google Scholar
• Piccinini, P., M. Piecha, and T. S. Fortaner. 2013. European survey on the content of lead in lip products. Journal Pharmaceutical Biomedical Analysis 76:225–33. doi:10.1016/j.jpba.2012.11.047.
   PubMed Web of Science ®Google Scholar
• Pinho, A. I., C. S. Oliveira, F. L. Lovato, E. P. Waczuk, B. C. Piccoli, A. A. Boligon, N. F. Leite, H. D. M. Coutinho, T. Posser, J. B. T. da Rocha, and J. L. Franco. 2017. Antioxidant and mercury chelating activity of Psidium guajava var. pomifera L. leaves hydroalcoholic extract. Journal of Toxicology and Environmental Health, Part A 80:1301–13. doi:10.1080/15287394.2017.1382408.
   PubMed Web of Science ®Google Scholar
• Poirier, J., H. Semple, J. Davies, R. Lapointe, M. Dziwenka, M. Hiltz, and D. Mujibi. 2011. Double blind, vehicle-controlled randomized twelve-month neurodevelopmental toxicity study of common aluminum salts in the rat. Neuroscience 193:338–62. doi:10.1016/j.neuroscience.2011.05.008.
   PubMed Web of Science ®Google Scholar
• Robinson, M. K., F. G. Gerberick, C. A. Ryan, P. M. McNamee, I. R. White, and D. A. Basketter. 2000. The importance of exposure estimation in the assessment of skin sensitization risk. Contact Dermatitis 42:251–59. doi:10.1034/j.1600-0536.2000.042005251.x.
   PubMed Web of Science ®Google Scholar
• Roper, S. C., and L. Stupart 2006. The in vitro percutaneous absorption of antimony trioxide through human skin. Charles River Laboratories Report No. 25985. Edinburgh, UK.
   Google Scholar
• Ryan, C., L. Cruse, R. Skinner, R. Dearman, I. Kimber, and G. Gerberick. 2002. Examination of a vehicle for use with water soluble materials in the murine local lymph node assay. Food and Chemical Toxicology 40:1719–26. doi:10.1016/S0278-6915(02)00116-3.
   PubMed Web of Science ®Google Scholar
• Safford, R. J. 2008. The Dermal Sensitization Threshold- a TTC approach for allergic contact dermatitis. Regulatory Toxicology and Pharmacology 51:195–200. doi:10.1016/j.yrtph.2008.02.010.
   PubMed Web of Science ®Google Scholar
• Sainio, E. L., R. Jolanki, E. Hakala, and L. Kanerva. 2000. Metals and arsenic in eye shadows. Contact Dermatitis 42:5–10. doi:10.1034/j.1600-0536.2000.042001005.x.
   PubMed Web of Science ®Google Scholar
• Sample, B. E., D. M. Opresko, and G. W. Suter, II. 1996. Toxicological benchmarks for wildlife; 1996 revision. ES/ER/TM-86, Oak Ridge Natinal Laboratory, OskRidge, TN Accessed June, 1996. https://www.osti.gov/scitech/biblio/258027.
   Google Scholar
• Sanner, T., and E. Dybing. 2005. Comparison of carcinogen hazard characterisation based on animal studies and epidemiology. Basic & Clinical Pharmacology & Toxicology 96:66–70. doi:10.1111/pto.2005.96.issue-1.
   PubMed Web of Science ®Google Scholar
• Sanner, T., E. Dybing, M. I. Willems, and E. D. Kroese. 2001. A simple method for quantitative risk assessment of non-threshold carcinogens based on the dose descriptor T25. Pharmacology & Toxicology 88:331–331. doi:10.1034/j.1600-0773.2001.880608.x.
   PubMedGoogle Scholar
• SCCS (Scientific Committee on Consumer Safety). 2012. The SCCS’s notes of guidance for the testing of cosmetic ingredients and their safety evaluation, 8th revision, SCCS/1501/12. https://ec.europa.eu/health/scientific_committees/consumer_safety/docs/sccs_s_006.pdf.
   Google Scholar
• Sneyers, L., L. Verheyen, P. Vermaercke, and M. Bruggemann. 2009. Trace element determination in beauty products by instrumental neutron activation analysis. Journal Radioanal Nuclear Chemical 281:259–63. doi:10.1007/s10967-009-0105-8.
   Web of Science ®Google Scholar
• Soares, A. R., and C. C. Nascentes. 2013. Development of a simple method for the determination of lead in lipstick using alkaline solubilization and graphite furnace atomic absorption spectrometry. Talanta 105:272–77. doi:10.1016/j.talanta.2012.09.021.
   PubMed Web of Science ®Google Scholar
• Thyssen, J. P., J. D. Johansen, and T. Menne. 2007. Contact allergy epidemics and their controls. Contact Dermatitis 56:185–95. doi:10.1111/j.1600-0536.2006.01058.x.
   PubMed Web of Science ®Google Scholar
• URF (Unit Risk Factor). 1999. List of compounds and their associated unit risk factors. http://www.aqmd.gov/docs/default-source/air-quality/air-toxic-studies/mates-ii/mates-ii-list-of-toxic-compounds-and-their-associated-unit-risk-factors-(urf).pdf?sfvrsn=4.
   Google Scholar
• US EPA (U.S. Environmental Protection Agency). 2010. Toxicology review of hexavalent chromium. http://www.epa.gov/iris/toxreviews/0144tr.pdf.
   Google Scholar
• US EPA. (U.S. Environmental Protection Agency). 2008. Provisional Peer Reviewed Toxicity Values (PPRTV) for Iron and Compounds (CASRN 7439-89-6). Derivation of chronic and subchronic oral RfDs, Superfund Health Risk Technical Support Center, National Center for Environmental Assessment, Office of Research and Development, U.S. Environmental Protection Agency, Cincinnati, OH, April 1.
   Google Scholar
• US FDA (U.S. Food and Drug Administration). 2000. Food and Drug Administration, 2000. Cosmetics: ingredients prohibited & restricted by FDA regulations. http://www.fda.gov/Cosmetics/ProductandIngredientSafety/SelectedCosmeticIngredients/ucm127406.html.
   Google Scholar
• US FDA (U.S. Food and Drug Administration). 2007. Summary of color additives listed for use in the United States in food, drugs, cosmetics, and medical devices, “Color additives approved for use in cosmetics part 73, subpart C: Color additives exempt from batch certification, United States Food and Drug Administration. http://www.fda.gov/ForIndustry/ColorAdditives/ColorAdditiveInventories/ucm115641.htm.
   Google Scholar
• US FDA (U.S. Food and Drug Administration). 2013. Food and Drug Administration, 2013. Title 21—Food and Drugs. Chapter I –Food and Drug Administration, Department of Health and Human Services. Part74 – Listing of color additives subject to certification. Sec. 74.1306 D&C Red No.6. http://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?fr=74.1306.
   Google Scholar
• Volpe, M. G., M. Nazzaro, R. Coppola, F. Rapuano, and R. P. Aquino. 2012. Determination and assessments of selected heavy metals in eye shadow cosmetics from China, Italy, and USA. Microchemical Journal 101:65–69. doi:10.1016/j.microc.2011.10.008.
   Web of Science ®Google Scholar
• Wester, R. C., H. I. Maibach, L. Sedik, J. Melendres, and M. Wade. 1993. Percutaneous-absorption of PCBs from soil – In-vivo rhesus-monkey, in-vitro human skin, and binding to powdered human stratumcorneum. Journal Toxicogical Environment Health 39:375–82. doi:10.1080/15287399309531758.
   PubMed Web of Science ®Google Scholar
• WHO (World Health Organization). 2008. The Scientific Basis of Tobacco Product Regulation: Second Report of a WHO. http://www.who.int/tobacco/global_interaction/tobreg/publications/9789241209519.pdf.
   Google Scholar
• WHO (World Health Organization). 2009. Concise international chemical assessment document 76, inorganic chromium (III) compounds. http://www.inchem.org/documents/cicads/cicads/cicad76.pdf.
   Google Scholar
• WHO/IPCS. 2012. Guidance for immunotoxicity risk assessment for chemicals. Harmonization Project Document No. 10. http://www.inchem.org/documents/harmproj/harmproj/harmproj10.pdf.
   Google Scholar
• Wu, X., S. Wei, Y. Wei, B. Guo, M. Yang, D. Zhao, X. Liu, and X. Cai. 2012. The reference dose for sub-chronic exposure of pigs to cadmium leading to early renal damage by benchmark dose method. Toxicological Sciences 128:524–31. doi:10.1093/toxsci/kfs173.
   PubMed Web of Science ®Google Scholar
• Wultsch, G., A. Nersesyan, M. Kundi, M. Mišík, T. Setayesh, M. Waldherr, P. Vodicka, L. Vodickova, and S. Knasmüller. 2017. Genotoxic and cytotoxic effects in exfoliated buccal and nasal cells of chromium and cobalt exposed electroplaters. Journal Toxicogical Environment Health A 80:651–60. doi:10.1080/15287394.2017.1286918.
   PubMed Web of Science ®Google Scholar