184
Views
5
CrossRef citations to date
0
Altmetric
Articles

Functional and structural liver abnormalities in former PCB exposed workers – analyses from the HELPcB cohort

ORCID Icon, , , , & ORCID Icon

References

  • Alvares, A. P., A. Fischbein, K. E. Anderson, and A. Kappas. 1977. Alterations in drug metabolism in workers exposed to polychlorinated biphenyls. Clin. Pharmacol. Ther. 22:140–46.
  • Baker, E. L., Jr., P. J. Landrigan, C. J. Glueck, M. M. Zack Jr., J. A. Liddle, V. W. Burse, W. J. Housworth, and L. L. Needham. 1980. Metabolic consequences of exposure to polychlorinated biphenyls (PCB) in sewage sludge. Am. J. Epidemiol. 112:553–63.
  • Bosetti, C., E. Negri, E. Fattore, and C. La Vecchia. 2003. Occupational exposure to polychlorinated biphenyls and cancer risk. Eur. J. Cancer Prevent. 12:251–55. doi:10.1097/00008469-200308000-00002.
  • Brown, D. P. 1987. Mortality of workers exposed to polychlorinated biphenyls–An update. Arch. Environ. Health. 42:333–39. doi:10.1080/00039896.1987.9934355.
  • Brown, J.F. Jr, B.A. Mayes, J.B. Silkworth, S.B. Hamilton. 2007. Polychlorinated biphenyls modulated tumorigenesis in Sprague Dawley rats: correlation with mixed function oxidase activities and Superoxid (O2*) formation potentials and implied mode of action. Toxicol Sci 98: 375–394.
  • Cave, M., S. Appana, M. Patel, K. C. Falkner, C. J. McClain, and G. Brock. 2010. Polychlorinated biphenyls, lead, and mercury are associated with liver disease in American adults: NHANES 2003–2004. Environ. Health Perspect. 118:1735–42. doi:10.1289/ehp.1002720.
  • Commission, MAK. 2016. Chlorinated biphenyls. MAK collection occupational Health safety, supplement 2013, 1. Wiley-VCH Verlag GmbH.
  • Esser, A., T. Schettgen, M. Gube, A. Koch, and T. Kraus. 2016. Association between polychlorinated biphenyls and diabetes mellitus in the German HELPcB cohort. Int. J. Hyg Environ. Health 219:557–65. doi:10.1016/j.ijheh.2016.06.001.
  • Fischbein, A. 1985. Liver function tests in workers with occupational exposure to polychlorinated biphenyls (PCBs): Comparison with Yusho and Yu-Cheng. Environ. Health Perspect. 60:145–50. doi:10.1289/ehp.8560145.
  • Fischbein, A., M. S. Wolff, R. Lilis, J. Thornton, and I. J. Selikoff. 1979. Clinical findings among PCB-exposed capacitor manufacturing workers*. Ann. N Y Acad. Sci. 320:703–15.
  • Fitzgerald, E. F., S. J. Standfast, L. G. Youngblood, J. M. Melius, and D. T. Janerich. 1986. Assessing the health effects of potential exposure to PCBs, dioxins, and furans from electrical transformer fires: The binghamton state office building medical surveillance program. Arch. Environ. Health 41:368–76. doi:10.1080/00039896.1986.9935781.
  • Gaum, P. M., J. Lang, A. Esser, T. Schettgen, J. Neulen, T. Kraus, and M. Gube. 2016. Exposure to polychlorinated biphenyls and the thyroid gland - examining and discussing possible longitudinal health effects in humans. Environ. Res. 148:112–21. doi:10.1016/j.envres.2016.03.022.
  • Golden, R., and R. Kimbrough. 2009. Weight of evidence evaluation of potential human cancer risks from exposure to polychlorinated biphenyls: An update based on studies published since 2003. Crit. Rev. Toxicol. 39:299–331. doi:10.1080/10408440802291521.
  • Hsu, S. T., C. I. Ma, S. K. Hsu, S. S. Wu, N. H. Hsu, C. C. Yeh, and S. B. Wu. 1985. Discovery and epidemiology of PCB poisoning in Taiwan: A four-year followup. Environ. Health Perspect. 59:5–10. doi:10.1289/ehp.59-1568088.
  • Kraus, T., M. Gube, J. Lang, A. Esser, W. Sturm, B. Fimm, K. Willmes, J. Neulen, J. M. Baron, H. Merk, et al. 2012. Surveillance program for former PCB-exposed workers of a transformer and capacitor recycling company, family members, employees of surrounding companies, and area residents–Executive summary. J. Toxicol. Environ. Health A 75:1241–47. doi:10.1080/15287394.2012.709377.
  • Kreiss, K., C. Roberts, and H. E. Humphrey. 1982. Serial PBB levels, PCB levels, and clinical chemistries in Michigan’s PBB cohort. Arch. Environ. Health 37:141–47.
  • Kunz, S., M. Schwarz, B. Schilling, O. Papke, H. J. Lehmler, L. W. Robertson, D. Schrenk, and H. J. Schmitz. 2006. Tumor promoting potency of PCBs 28 and 101 in rat liver. Toxicol. Lett. 164:133–43. doi:10.1016/j.toxlet.2005.12.003.
  • Kutlu, S., N. Colakoglu, I. Halifeoglu, S. Sandal, A. D. Seyran, M. Aydin, and B. Yilmaz. 2007. Comparative evaluation of hepatotoxic and nephrotoxic effects of Aroclors 1221 and 1254 in female rats. Cell Biochem. Funct. 25:167–72. doi:10.1002/cbf.1289.
  • Lehmann, L., L. Esch H, A. Kirby P, W. Robertson L, and G. Ludewig. 2007. 4-monochlorobiphenyl (PCB3) induces mutations in the livers of transgenic Fisher 344 rats. Carcinogenesis 28:471–78. doi:10.1093/carcin/bgl157.
  • Mallin, K., K. McCann, A. D’Aloisio, S. Freels, J. Piorkowski, J. Dimos, and V. Persky. 2004. Cohort mortality study of capacitor manufacturing workers, 1944–2000. J. Occup. Environ. Med. 46:565–76.
  • Maroni, M., A. Colombi, G. Arbosti, S. Cantoni, and V. Foa. 1981. Occupational exposure to polychlorinated biphenyls in electrical workers. II. Health effects. Br. J. Ind. Med. 38:55–60.
  • Onozuka, D., T. Yoshimura, S. Kaneko, and M. Furue. 2009. Mortality after exposure to polychlorinated biphenyls and polychlorinated dibenzofurans: A40-year follow-up study of Yusho patients. Am. J. Epidemiol. 169:86–95. doi:10.1093/aje/kwn295.
  • Ounnas, F., F. Prive, F. Lamarche, P. Salen, I. Favier-Hininger, P. Marchand, B. Le Bizec, A. Venisseau, C. Batandier, E. Fontaine, et al. 2016. A relevant exposure to a food matrix contaminated environmentally by polychlorinated biphenyls induces liver and brain disruption in rats. Chemosphere 161:80–88. doi:10.1016/j.chemosphere.2016.06.040.
  • Ouw, H. K., G. R. Simpson, and D. S. Siyali. 1976. Use and health effects of Aroclor 1242, a polychlorinated biphenyl, in an electrical industry. Arch. Environ. Health 31:189–94.
  • Reggiani, G., and R. Bruppacher. 1985. Symptoms, signs and findings in humans exposed to PCBs and their derivatives. Environ. Health Perspect. 60:225–32. doi:10.1289/ehp.8560225.
  • Safe, S. 1993. Toxicology, structure-function relationship, and human and environmental health impacts of polychlorinated biphenyls: Progress and problems. Environ. Health Perspect. 100:259–68. doi:10.1289/ehp.93100259.
  • Sattar, N., E. Forrest, and D. Preiss. 2014. Non-alcoholic fatty liver disease. BMJ 349:g4596. doi:10.1136/bmj.g4596.
  • Schettgen, T., A. Alt, D. Preim, D. Keller, and T. Kraus. 2012a. Biological monitoring of indoor-exposure to dioxin-like and non-dioxin-like polychlorinated biphenyls (PCB) in a public building. Toxicol. Lett. 213:116–21. doi:10.1016/j.toxlet.2011.06.005.
  • Schettgen, T., M. Gube, A. Esser, A. Alt, and T. Kraus. 2012b. Plasma polychlorinated biphenyls (PCB) levels of workers in a transformer recycling company, their family members, and employees of surrounding companies. J. Toxicol. Environ. Health A 75:414–22. doi:10.1080/15287394.2012.674905.
  • Schisterman, E. F., B. W. Whitcomb, G. M. Louis, and T. A. Louis. 2005. Lipid adjustment in the analysis of environmental contaminants and human health risks. Environ. Health Perspect. 113:853–57. doi:10.1289/ehp.7640.
  • Serdar, B., W. G. LeBlanc, J. M. Norris, and L. M. Dickinson. 2014. Potential effects of polychlorinated biphenyls (PCBs) and selected organochlorine pesticides (OCPs) on immune cells and blood biochemistry measures: A cross-sectional assessment of the NHANES 2003–2004 data. Environ. Health 13:114. doi:10.1186/1476-069X-13-113.
  • Smith, A. B., J. Schloemer, L. K. Lowry, A. W. Smallwood, R. N. Ligo, S. Tanaka, W. Stringer, M. Jones, R. Hervin, and C. J. Glueck. 1982. Metabolic and health consequences of occupational exposure to polychlorinated biphenyls. Br. J. Ind. Med. 39:361–69.
  • van der Plas, S. A., M. Haag-Gronlund, G. Scheu, L. Warngard, M. van Den Berg, P. Wester, J. H. Koeman, and A. Brouwer. 1999. Induction of altered hepatic foci by a mixture of dioxin-like compounds with and without 2,2,4,4,5,5-hexachlorobiphenyl in female Sprague-Dawley rats. Toxicol. Appl. Pharmacol. 156:30–39. doi:10.1006/taap.1999.8629.
  • Warner, N. A., J. W. Martin, and C. S. Wong. 2009. Chiral polychlorinated biphenyls are biotransformed enantioselectively by mammalian cytochrome P-450 isozymes to form hydroxylated metabolites. Environ. Sci. Technol. 43:114–21.
  • Ziegler, S., T. Schettgen, F. Beier, S. Wilop, N. Quinete, A. Esser, B. K. Masouleh, M. S. Ferreira, L. Vankann, P. Uciechowski, et al. 2017. Accelerated telomere shortening in peripheral blood lymphocytes after occupational polychlorinated biphenyls exposure. Arch. Toxicol. 91:289–300. doi:10.1007/s00204-016-1725-8.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.