Inhibition of oxidative stress by testosterone improves synaptic plasticity in senescence accelerated mice

References

• Alsemari, A. 2013. Hypogonadism and neurological diseases. Neurol. Sci. 34:629–38. doi:10.1007/s10072-012-1278-4.
   PubMed Web of Science ®Google Scholar
• Atwi, S., D. McMahon, H. Scharfman, and N. J. MacLusky. 2016. Androgen modulation of hippocampal structure and function. Neuroscientist 22:46–60. doi:10.1177/1073858414558065.
   PubMed Web of Science ®Google Scholar
• Aybek, H., F. Ercan, D. Aslan, and T. Sahiner. 2007. Determination of malondialdehyde, reduced glutathione levels and APOE4 allele frequency in late-onset Alzheimer’s disease in Denizli, Turkey. Clin. Biochem. 40:172–76. doi:10.1016/j.clinbiochem.2006.09.005.
   PubMed Web of Science ®Google Scholar
• Berridge, M. J., and R. F. Irvine. 1989. Inositol phosphates and cell signalling. Nature 341:197–205. doi:10.1038/341197a0.
   PubMed Web of Science ®Google Scholar
• Candemir, M., S. Semiz, G. N. Yonguc, M. B. Ozdemir, G. Abban-Mete, and E. Adiguzel. 2013. Effect of testosterone propionate on hippocampal pyramidal neuron number in female rats. Singapore Med. J. 54:315–20. doi:10.11622/smedj.2013124.
   PubMed Web of Science ®Google Scholar
• Carafoli, E., L. Santella, D. Branca, and M. Brini. 2001. Generation, control, and processing of cellular calcium signals. Crit. Rev. Biochem. Mol. Biol. 36:107–260. doi:10.1080/20014091074183.
   PubMed Web of Science ®Google Scholar
• De Felice, F. G., P. T. Velasco, M. P. Lambert, K. Viola, S. J. Fernandez, S. T. Ferreira, and W. L. Klein. 2007. A-beta oligomers induce neuronal oxidative stress through an N-methyl-D-aspartate receptor dependent mechanism that is blocked by the Alzheimer drug memantine. J. Biol. Chem. 282:11590–601. doi:10.1074/jbc.M607483200.
   PubMed Web of Science ®Google Scholar
• Driscoll, I., D. A. Hamilton, R. A. Yeo, W. M. Brooks, and R. J. Sutherland. 2005. Virtual navigation in humans: The impact of age, sex, and hormones on place learning. Horm. Behav. 47:326–35. doi:10.1016/j.yhbeh.2004.11.013.
   PubMed Web of Science ®Google Scholar
• Drummond, E. S., A. R. Harvey, and R. N. Martins. 2009. Androgens and Alzheimer’s disease. Curr. Opin. Endocrinol. Diabetes Obes 16:254–59. doi:10.1097/MED.0b013e32832b101f.
   PubMedGoogle Scholar
• Holland, J., S. Bandelow, and E. Hogervorst. 2011. Testosterone levels and cognition in elderly men: A review. Maturitas 69::322–37. doi:10.1016/j.maturitas.2011.05.012.
   PubMed Web of Science ®Google Scholar
• Huo, D. S., J. F. Sun, B. F. Zhang, X. S. Yan, H. Wang, J. X. Jia, and Z. J. Yang. 2016. Protective effects of testosterone on cognitive dysfunction in Alzheimer’s disease model rats induced by oligomeric beta amyloid peptide 1-42. J. Toxicol. Environ. Health A 79:856–63. doi:10.1080/15287394.2016.1193114.
   PubMed Web of Science ®Google Scholar
• Jia, J. X., C. L. Cui, W. Song, X. S. Yan, D. S. Huo, H. Wang, and Z. J. Yang. 2015. Effects of testosterone treatment on synaptic plasticity and behavior in senescence accelerated mice. J. Toxicol. Environ. Health A 78:1311–20. doi:10.1080/15287394.2015.1085839.
   PubMed Web of Science ®Google Scholar
• Jia, J. X., C. L. Cui, X. S. Yan, B. F. Zhang, W. Song, D. S. Huo, H. Wang, and Z. J. Yang. 2016. Effects of testosterone on synaptic plasticity mediated by androgen receptors in male SAMP8 mice. J. Toxicol. Environ. Health A 79:849–55. doi:10.1080/15287394.2016.1193113.
   PubMed Web of Science ®Google Scholar
• Jia, J. X., L. Kang, S. Li, D. Geng, P. Fan, L. Wang, and H. X. Cui. 2013. Amelioratory effects of testosterone treatment on cognitive performance deficits induced by soluble Aβ1-42 oligomers injected into the hippocampus. Horm. Behav. 64:477–86. doi:10.1016/j.yhbeh.2013.08.002.
   PubMed Web of Science ®Google Scholar
• Jing, W., F. J. Michael, and F. X. Yu. 2016. Glia and TRPM2 channels in plasticity of central nervous system and Alzheimer’s diseases. Neural Plast. 7:1–7.
   Google Scholar
• Kamat, P. K., A. Kalani, S. Rai, S. Swarnkar, S. Tota, C. Nath, and N. Tyagi. 2016. Mechanism of oxidative stress and synapse dysfunction in the pathogenesis of Alzheimer’s disease: Understanding the therapeutics strategies. Mol. Neurobiol. 53:648–61. doi:10.1007/s12035-014-9053-6.
   PubMed Web of Science ®Google Scholar
• Lacor, P. N., M. C. Buniel, P. W. Furlow, A. S. Clemente, P. T. Velasco, M. Wood, K. L. Viola, and W. L. Klein. 2007. A-beta oligomer-induced aberrations in synapse composition, shape, and density provide a molecular basis for loss of connectivity in Alzheimer’s disease. J. Neurosci. 27:796–807. doi:10.1523/JNEUROSCI.3501-06.2007.
   PubMed Web of Science ®Google Scholar
• Lau, C. G., and R. S. Zukin. 2007. NMDA receptor trafficking in synaptic plasticity and neuropsychiatric disorders. Nat. Rev. Neurosci. 8:413–26. doi:10.1038/nrn2153.
   PubMed Web of Science ®Google Scholar
• Leranth, C., T. Hajszan, and N. J. MacLusky. 2004. Androgens increase spine synapse density in the CA1 hippocampal subfield of ovariectomized female rats. J. Neurosci. 14:495–99. doi:10.1523/JNEUROSCI.4516-03.2004.
   Google Scholar
• Little, C. M., K. D. Coons, and D. R. Sengelaub. 2009. Neuroprotective effects of testosterone on the morphology and function of somatic motoneurons following the death of neighboring motoneurons. J. Comp. Neurol. 512:359–72. doi:10.1002/cne.v512:3.
   PubMed Web of Science ®Google Scholar
• Liu, L., I. J. Orozco, E. Planel, Y. Wen, A. Bretteville, P. Krishnamurthy, L. Wang, M. Herman, H. Figueroa, W. H. Yu, et al. 2008. A transgenic rat that develops Alzheimer’s disease-like amyloid pathology, deficits in synaptic plasticity and cognitive impairment. Neurobiol. Dis. 31::46–57. doi:10.1016/j.nbd.2008.03.005.
   PubMed Web of Science ®Google Scholar
• Marron, T. U., V. Guerini, P. Rusmini, D. Sau, T. A. Brevini, L. Martini, and A. Poletti. 2005. Androgen-induced neurite outgrowth is mediated by neuritin in motor neurones. J. Neurochem. 92:10–20. doi:10.1111/jnc.2005.92.issue-1.
   PubMed Web of Science ®Google Scholar
• Milner, B., L. R. Squire, and E. R. Kandel. 1998. Cognitive neuroscience and the study of memory. Neuron 20:445–68. doi:10.1016/S0896-6273(00)80987-3.
   PubMed Web of Science ®Google Scholar
• Mukai, H., T. Kimoto, Y. Hojo, S. Kawato, G. Murakami, S. Higo, Y. Hatanaka, and M. Ogiue-Ikeda. 2010. Modulation of synaptic plasticity by brain estrogen in the hippocampus. Biochim. Biophys. Acta. 1800:1030–44. doi:10.1016/j.bbagen.2009.11.002.
   PubMed Web of Science ®Google Scholar
• Nunez, J. L., H. A. Jurgens, and J. M. Juraska. 2000. Androgens reduce cell death in the developing rat visual cortex. Brain Res. Dev. Brain Res. 125:83–88. doi:10.1016/S0165-3806(00)00126-7.
   PubMedGoogle Scholar
• Parameshwaran, K., M. Dhanasekaran, and V. Suppiramaniam. 2008. Amyloid beta peptides and glutamatergic synaptic dysregulation. Exp. Neurol. 210:7–13. doi:10.1016/j.expneurol.2007.10.008.
   PubMed Web of Science ®Google Scholar
• Perez-Otano, I., and M. D. Ehlers. 2005. Homeostatic plasticity and NMDA receptor trafficking. Trends Neurosci. 28:229–38. doi:10.1016/j.tins.2005.03.004.
   PubMed Web of Science ®Google Scholar
• Pike, C. J., J. C. Carroll, E. R. Rosario, and A. M. Barron. 2009. Protective actions of sex steroid hormones in Alzheimer’s disease. Front. Neuroendocrinol. 30:239–58. doi:10.1016/j.yfrne.2009.04.015.
   PubMed Web of Science ®Google Scholar
• Pike, C. J., T. V. Nguyen, M. Ramsden, M. Yao, M. P. Murphy, and R. Rosario. 2008. Androgen cell signaling pathways involved in neuroprotective actions. Horm. Behav. 53:693–705. doi:10.1016/j.yhbeh.2007.11.006.
   PubMed Web of Science ®Google Scholar
• Rodrigo, G. R., N. M. Mauricio, V. S. Karina, A. S. Daniel, and M. M. Laura. 2017. Involvement of astrocytes in Alzheimer’s disease from a neuroinflammatory and oxidative stress perspective. Front. Mol. Neurosci. 10:1–20. doi:10.3389/fnmol.2017.00001.
   PubMed Web of Science ®Google Scholar
• Rosario, E. R., and C. J. Pike. 2008. Androgen regulation of β-amyloid protein and the risk of Alzheimer’s disease. Brain Res. Rev. 57:444–53. doi:10.1016/j.brainresrev.2007.04.012.
   PubMedGoogle Scholar
• Salissou, M. T. M., Y. A. R. Mahaman, F. Zhu, F. Huang, Y. Wang, Z. Xu, D. Ke, Q. Wang, R. Liu, J.-Z. Wang, et al. 2018. Methanolic extract of Tamarix gallica attenuates hyperhomocysteinemia induced AD-like pathology and cognitive impairments in rats. Aging 10:3229–48. doi:10.18632/aging.101627.
   PubMedGoogle Scholar
• Son, S. W., J. S. Lee, H. G. Kim, D. W. Kim, Y. C. Ahn, and C. G. Son. 2016. Testosterone depletion increases the susceptibility of brain tissue to oxidative damage in a restraint stress mouse model. J. Neurochem. 136:106–17. doi:10.1111/jnc.13371.
   PubMed Web of Science ®Google Scholar
• Spritzer, M. D., and L. A. Galea. 2007. Testosterone and dihydrotestosterone, but not estradiol, enhance survival of new hippocampal neurons in adult male rats. Neurobiology. 67:1321–33. doi:10.1002/dneu.20457.
   Google Scholar
• Zu, H., J. Wu, J. Zhang, M. Yu, and Z. Hong. 2012. Testosterone up-regulates seladin-1 expression by iAR and PI3-K/Akt signaling pathway in C6 cells. Neurosci. Lett. 514:122–26. doi:10.1016/j.neulet.2012.02.072.
   PubMed Web of Science ®Google Scholar