References
- Alaraby, M., B. Annangi, R. Marcos, and A. Hernandéz. 2016. Drosophila melanogaster as a suitable in vivo model to determine potential side effects of nanomaterials: A review. J. Toxicol. Environ. Health B. 19 (2):65–104. doi:https://doi.org/10.1080/10937404.2016.1166466.
- Almaliki, H. S., A. Angela, N. J. Goraya, G. Yin, and J. W. Bennett. 2021. Volatile organic compounds produced by human pathogenic fungi are toxic to drosophila melanogaster. Front. Fungal Biol. 1:1–11. doi:https://doi.org/10.3389/ffunb.2020.629510.
- Annesi-Maesano, I., N. Baiz, S. Banerjee, P. Rudnai, and S. Rive. 2013. Indoor air quality and sources in schools and related health effects. J. Toxicol. Environ. Health B. 16 (8):491–550. doi:https://doi.org/10.1080/10937404.2013.853609.
- Araki, A., T. Kawai, Y. Eitaki, A. Kanazawa, K. Morimoto, K. Nakayama, E. Shibata, M. Tanaka, T. Takigawa, T. Yoshimura, et al. 2010. Relationship between selected indoor volatile organic compounds, so-called microbial VOC, and the prevalence of mucous membrane symptoms in single family homes. Sci. Total Environ. 408 (10):2208–15. doi:https://doi.org/10.1016/j.scitotenv.2010.02.012.
- Aun, M. V., R. Bonamichi-Santos, F. M. Arantes-Costa, J. Kalil, and P. Giavina-Bianchi. 2018. Animal models of asthma: Utility and limitations. J. Asthma Allergy 10:293–301. doi:https://doi.org/10.2147/JAA.S121092.
- Bennett, J. W., and A. A. Inamdar. 2015. Are some fungal volatile organic compounds (VOCs) mycotoxins? Toxins 7 (9):3785–804. doi:https://doi.org/10.3390/toxins7093785.
- Boovarahan, S. R., and G. A. Kurian. 2018. Mitochondrial dysfunction: A key player in the pathogenesis of cardiovascular diseases linked to air pollution. Rev. Environ. Health 33 (2):111–22. doi:https://doi.org/10.1515/reveh-2017-0025.
- Bradford, M. M. 1976. A rapid and sensitive method for the quantitation microgram quantities of protein utilizing the principle of protein-dye binding. Anal. Biochem. 72 (1–2):248–54. doi:https://doi.org/10.1006/abio.1976.9999.
- Breton, C. V., A. Y. Song, J. Xiao, S.-J. Kim, H. H. Mehta, J. Wan, K. Yen, C. Sioutas, F. Lurmann, S. Xue, et al. 2019. Effects of air pollution on mitochondrial function, mitochondrial D.N.A. methylation, and mitochondrial peptide expression. Mitochondrion 46:22–29. doi:https://doi.org/10.1016/j.mito.2019.04.001.
- Casimir, G. J., N. Lefèvre, F. Corazza, J. Duchateau, and M. Chamekh. 2018. The acid-base balance and gender in inflammation: A mini-review. Front Immunol. 9:1–6. doi:https://doi.org/10.3389/fimmu.2018.00475.
- Chan, F. L., C.-Y. Hon, S. M. Tarlo, N. Rajaram, and R. House. 2020. Emissions and health risks from the use of 3D printers in an occupational setting. J. Toxicol. Environ. Health Part A 83 (7):279–87. doi:https://doi.org/10.1080/15287394.2020.1751758.
- Chew, S., R. Lampinen, L. Saveleva, P. Korhonen, N. Mikhailov, A. Grubman, J. M. Polo, T. Wilson, M. Komppula, T. Rönkkö, et al. 2020. Urban air particulate matter induces mitochondrial dysfunction in human olfactory mucosal cells. Part Fibre Toxicol. 17 (1):1–15. doi:https://doi.org/10.1186/s12989-020-00352-4.
- Cincinelli, A., and T. Martellini. 2017. Indoor air quality and health. Int. J. Environ. Res. Public Health 14 (11):1–5. doi:https://doi.org/10.3390/ijerph14111286.
- Costa-Silva, D. G., A. R. Lopes, I. K. Martins, L. P. Leandro, M. E. M. Nunes, N. R. de Carvalho, N. R. Rodrigues, G. E. Macedo, A. P. Saidelles, C. Aguiar, et al. 2018. Mancozeb exposure results in manganese accumulation and Nrf2-related antioxidant responses in the brain of common carp Cyprinus carpio. Environ. Sci. Pollut. Res. 25 (16):15529–40. doi:https://doi.org/10.1007/s11356-018-1724-9.
- Czubaj-Kowal, M., R. Kurzawa, H. Mazurek, M. Sokołowski, T. Friediger, M. Polak, and G. J. Nowicki. 2021. Relationship between air pollution and the concentration of nitric oxide in the exhaled air (feno) in 8–9-year-old school children in Krakow. Int. J. Environ. Res. Public Health 18 (13):1–13. doi:https://doi.org/10.3390/ijerph18136690.
- Demir, E. 2021. Adverse biological effects of ingested polystyrene microplastics using drosophila melanogaster as a model in vivo organism. J. Toxicol. Environ. Health Part A 84 (16):649–60. doi:https://doi.org/10.1080/15287394.2021.1913684.
- Demir, F. T., Y.-J. Lee, S. J. Kim, J. D. Lee, S. Kim, M. J. Ko, J.-W. Kim, C. Y. Shin, and K.-B. Kim. 2022. In vivo effects of 1,4-dioxane on genotoxic parameters and behavioral alterations in Drosophila melanogaster. J. Toxicol. Environ. Health Part A 85(1):1–17. 2027832. doi:https://doi.org/10.1080/15287394.2022.
- Dezest, M., M. Le Bechec, L. Chavatte, V. Desauziers, B. Chaput, J. Grolleau, P. Descargues, C. Nizard, S. Schnebert, S. Lacombe, et al. 2017. Oxidative damage and impairment of protein quality control systems in keratinocytes exposed to a volatile organic compounds cocktail. Sci. Rep. 7 (1):–14. doi:https://doi.org/10.1038/s41598-017-11088-1.
- Dominski, F. H., J. H. L. Branco, G. Buonanno, L. Stabile, M. G. S. da Silva, and A. Andrade. 2021. Effects of air pollution on health: A mapping review of systematic reviews and meta-analyses. Environ. Res. 201. doi:https://doi.org/10.1016/j.envres.2021.111487.
- Duan, C., S. Zuo, Z. Wu, Y. Qiu, J. Wang, Y. Lei, H. Liao, and Y. Ren. 2021. A review of research hotspots and trends in biogenic volatile organic compounds (BVOCs) emissions combining bibliometrics with evolution tree methods. Environ. Res. Lett. 16 (1):1–13. doi:https://doi.org/10.1088/1748-9326/abcee9.
- Eckel, P. S., Z. Zhang, R. Habre, E. B. Rappaport, W. S. Linn, K. Berhane, Y. Zhang, T. M. Bastain, and F. D. Gilliland. 2016. Traffic-related air pollution and alveolar nitric oxide in southern California children. Eur. Respir. J. 47 (5):1348–56. doi:https://doi.org/10.1183/13993003.01176-2015.
- Eleftherianos, I., K. More, S. Spivack, E. Paulin, A. Khojandi, and S. Shukla. 2014. Nitric oxide levels regulate the immune response of drosophila melanogaster reference laboratory strains to bacterial infections. Infect. Immun. 82 (10):4169–81. doi:https://doi.org/10.1128/IAI.02318-14.
- Eom, H. J., Y. Liu, G. S. Kwak, M. Heo, K. S. Song, Y. D. Chung, T. S. Chon, and J. Choi. 2017. Inhalation toxicity of indoor air pollutants in drosophila melanogaster using integrated transcriptomics and computational behavior analyses. Sci. Rep. 7 (1):1–15. doi:https://doi.org/10.1038/srep46473.
- EPA 2021. Indoor air quality (IAQ). what are volatile organic compounds (VOCs)? Acessed September 21, 2021. https://www.epa.gov/indoor-air-quality-iaq/what-are-volatile-organic-compounds-vocs
- FAO 2002. Food safety and quality. Online Edition: “Specifications for Flavourings.” Acessed September 28, 2021. https://www.fao.org/food/food-safety-quality/scientific-advice/jecfa/jecfa-flav/details/en/c/1084/
- Faraji, M., R. N. Nodehi, K. Naddafi, Z. Pourpak, Z. Alizadeh, S. Rezaei, and A. Mesdaghinia. 2018. Cytotoxicity of airborne particulate matter (PM 10) from dust storm and inversion conditions assessed by MTT assay. J. Air Pollut. Health 3:135–42.
- Gandhi, S. K., D. Q. Rich, P. A. Ohman-Strickland, H. M. Kipen, and A. Gow. 2014. Plasma nitrite is an indicator of acute changes in ambient air pollutant concentrations. Inhal. Toxicol. 26 (7):426–34. doi:https://doi.org/10.3109/08958378.2014.913216.
- Gillis, E. E., K. N. Brinson, O. Rafikova, W. Chen, J. B. Musall, D. G. Harrison, and J. C. Sullivan. 2018. Oxidative stress induces B.H. 4 deficiency in male, but not female, S.H.R. Biosci. Rep. 38 (4):1–12. doi:https://doi.org/10.1042/BSR20180111.
- Inamdar, A. A., and J. W. Bennett. 2014. A common fungal volatile organic compound induces a nitric oxide mediated inflammatory response in Drosophila melanogaster. Sci. Rep. 4:1–9. doi:https://doi.org/10.1038/srep03833.
- Inamdar, A. A., M. M. Hossain, A. I. Bernstein, G. W. Miller, J. R. Richardson, and J. W. Bennett. 2013. Fungal-derived semiochemical 1-octen-3-ol disrupts dopamine packaging and causes neurodegeneration. Proc. Natl. Acad. Sci. U.S.A. 110 (48):19561–66. doi:https://doi.org/10.1073/pnas.1318830110.
- Inamdar, A. A., P. Masurekar, and J. W. Bennett. 2010. Neurotoxicity of fungal volatile organic compounds in drosophila melanogaster. Toxicol. Sci. 117 (2):418–26. doi:https://doi.org/10.1093/toxsci/kfq222.
- Inamdar, A. A., P. Masurekar, M. Hossain, J. R. Richardson, and J. W. Bennett. 2014. Signaling pathways involved in 1-octen-3-ol-mediated neurotoxicity in drosophila melanogaster: Implication in parkinson’s disease. Neurotoxicol Res. 25 (2):183–91. doi:https://doi.org/10.1007/s12640-013-9418-z.
- Inamdar, A.A., J.C.Moore., R.I.Cohenl, and J.W.Bennett. 2012. A model to evaluate the cytotoxicity of the fungal volatile organic compound 1-octen-3-ol in human embryonic stem cells. Mycopathologia. 173:13–20. doi:https://doi.org/10.1007/s11046-011-9457-z
- Inamdar, A. A., S. Morath, and J. W. Bennett. 2020. Fungal volatile organic compounds: More than just a funky smell? Annu. Rev. Microbiol. 74 (1):101–16. doi:https://doi.org/10.1146/annurev-micro-012420-080428.
- Jain, R. B. 2015. Distributions of selected urinary metabolites of volatile organic compounds by age, gender, race/ethnicity, and smoking status in a representative sample of U.S. adults. Environ. Toxicol. Pharmacol. 40 (2):471–79. doi:https://doi.org/10.1016/j.etap.2015.07.018.
- Kalender-Smajlovic, S., M. Dovjak, and A. Kukec. 2021. Sick building syndrome among healthcare workers and healthcare associates at observed general hospital in Slovenia. Cent. Eur. J. Public Health 29 (1):28–37. doi:https://doi.org/10.21101/cejph.a6108.
- Kim, J. L., L. Elfman, Y. Mi, G. Wieslander, G. Smedje, and D. Norbäck. 2007. Indoor molds, bacteria, microbial volatile organic compounds and plasticizers in schools–associations with asthma and respiratory symptoms in pupils. Indoor. Air 17 (2):153–63. doi:https://doi.org/10.1111/j.1600-0668.2006.00466.x.
- Korpi, A., J. Järnberg, and A.-L. Pasanen. 2009. Microbial volatile organic compounds. Crit. Rev. Toxicol. 39 (2):139–93. doi:https://doi.org/10.1080/10408440802291497.
- Korpi, A., J. P. Kasanen, A.-L. Pasanen, Y. Alarie, and V. M. Kosma. 1999. Sensory irritating potency of some microbial volatile organic compounds (MVOCs) and a mixture of five MVOCs. Arch. Environ. Health 54 (5):347–52. doi:https://doi.org/10.1080/00039899909602499.
- Kozlov, A., R. Koch, and E. Nagoshi. 2020. Nitric oxide mediates neuro-glial interaction that shapes drosophila circadian behavior. PLoS Genet. 16 (6):1–21. doi:https://doi.org/10.1371/journal.pgen.1008312.
- Kreja, L., and H.-J. Seidel. 2002a. Evaluation of the genotoxic potential of some microbial volatiles organic compounds (MVOC) with the comet assay, the micronucleus assay and the HPRT gene mutation assay. Mutat.Res. 513 (1–2):143–50. doi:https://doi.org/10.1016/s1383-5718(01)00306-0.
- Kreja, L., and H.-J. Seidel. 2002b. On the cytotoxicity of some microbial volatile organic compounds as studied in the human lung cell line A549. Chemosphere 49 (1):105–10. doi:https://doi.org/10.1016/s0045-6535(02)00159-5.
- Kwon, J.-W., H.-W. Park, W. J. Kim, M.-G. Kim, and S.-J. Lee. 2018. Exposure to volatile organic compounds and airway inflammation. Environ. Health 17 (1):1–8. doi:https://doi.org/10.1186/s12940-018-0410-1.
- Lee, W., S. Y. Jeong, M. J. Gu, J. S. Lim, E. K. Park, M.-C. Baek, J.-S. Kim, D. Hahn, and J.-S. Bae. 2019b. Inhibitory effects of compounds isolated from dioscorea batatas decne peel on particulate matter-induced pulmonary injury in mice. J. Toxicol. Environ. Health Part A 82 (12):727–40. doi:https://doi.org/10.1080/15287394.2019.1646174.
- Lee, H., D. H. Kim, J.-H. Kim, S.-K. Park, J.-W. Jeong, M.-Y. Kim, S.-H. Hong, K. S. Song, G.-Y. Kim, J. W. Hyun, et al. 2021. Urban aerosol particulate matter promotes necrosis and autophagy via reactive oxygen species-mediated cellular disorders that are accompanied by cell cycle arrest in retinal pigment epithelial cells. Antioxidants 10:1–16. doi:https://doi.org/10.3390/antiox10020149.
- Lee, B.-M., S. Kwon, Y. M. Cho, K.-B. Kim, K. Seo, C. S. Min, and K. Kim. 2019a. Perspectives on trace chemical safety and chemophobia: Risk communication and risk management. J. Toxicol. Environ. Health Part A 82 (3):186–99. doi:https://doi.org/10.1080/15287394.2019.1575625.
- León-Mejía, G., L. F. O. Silva, M. S. Civeira, M. L. S. Oliveira, M. Machado, I. V. Villela, A. Hartmann, S. Premoli, D. S. Côrrea, J. da Silva, et al. 2016. Cytotoxicity and genotoxicity induced by coal and coal fly ash particles samples in V79 cells. Environ. Sci. Pollut. Res. Int. 23 (23):24019–31. doi:https://doi.org/10.1007/s11356-016-7623-z.
- Levine, B. D., and R. L. Cagan. 2016. Drosophila lung cancer models identify trametinib plus statin as candidate therapeutic. Cell. Rep. 14 (6):1477–87. doi:https://doi.org/10.1016/j.celrep.2015.12.105.
- Macedo, G. E., K. K. Gomes, N. R. Rodrigues, I. K. Martins, G. L. Wallau, N. R. de Carvalho, L. C. da Cruz, D. G. Costa-Silva, A. A. Boligon, J. L. Franco, et al. 2017. Senecio brasiliensis impairs eclosion rate and induces apoptotic cell death in larvae of Drosophila melanogaster. Comp. Biochem. Physiol. C Toxicol. Pharmacol. 198:45–57. doi:https://doi.org/10.1016/j.cbpc.2017.05.004.
- Macedo, G. E., P. B. Vieira, N. R. Rodrigues, K. K. Gomes, I. K. Martins, J. L. Franco, and T. Posser. 2020. Fungal compound 1-octen-3-ol induces mitochondrial morphological alterations and respiration dysfunctions in drosophila melanogaster. Ecotoxicol. Environ. Saf. 206:1–8. doi:https://doi.org/10.1016/j.ecoenv.2020.111232.
- Morey, P., A. Worthan, A. Weber, E. Homer, M. Black, and W. Muller. 1997. Microbial VOCs in moisture damaged buildings. In Proceedings of Healthy Buildings/IAQ ‘97. Global Issues and Regional Solutions, ed. J. E. Wood, D. T. Grimsrud, and B. N. Bethesda, Blacksburg, VA./U.S.A.: Virginia Polytechnic Institute and State University Printing Services. pp.245–50.
- Norbäck, D., and G.-H. Cai. 2020. Microbial agents in the indoor environment: Associations with health. In Indoor environmental quality and health risk toward healthier environment for all, ed. R. Kishi, D. Norbäck, and A. Araki, 179–98. Singapore City./S.I.N: Springer Nature Singapore Pte Ltd.
- O’Brien, J., I. Wilson, T. Orton, and F. Pognan. 2000. Investigation of the alamar blue (resazurin) fluorescent dye for the assessment of mammalian cell cytotoxicity. Eur. J. Biochem. 267 (17):5421–26. doi:https://doi.org/10.1046/j.1432-1327.2000.01606.x.
- Paciência, I., J. Madureira, J. Rufo, A. Moreira, and E. O. Fernandes. 2016. A systematic review of evidence and implications of spatial and seasonal variations of volatile organic compounds (VOC) in indoor human environments. J. Toxicol. Environ. Health B. 19:47–64. doi:https://doi.org/10.1080/10937404.2015.1134371.
- Pandey, U. B., and C. D. Nichols. 2011. Human disease models in drosophila melanogaster and the role of the fly in therapeutic drug discovery. Pharmacol. Rev. 63 (2):411–36. doi:https://doi.org/10.1124/pr.110.003293.
- Pasyukova, E. G., S. V. Nuzhdin, T. V. Morozova, and T. F. C. Mackay. 2004. Accumulation of transposable elements in the genome of Drosophila melanogaster is associated with a decrease in fitness. J. Heredity 95 (4):284–90. doi:https://doi.org/10.1093/jhered/esh050.
- Peng, H., X. H. Zhao, T. T. Bi, X. Y. Yuan, J. Bin Guo, and S. Q. Peng. 2017. PM2.5 obtained from urban areas in Beijing induces apoptosis by activating nuclear factor-Kappa B. Mil. Med. Res. 4:1–10. doi:https://doi.org/10.1186/s40779-017-0136-3.
- Rai, Y., R. Pathak, N. Kumari, D. K. Sah, S. Pandey, N. Kalra, R. Soni, B. S. Dwarakanath, and A. N. Bhatt. 2018. Mitochondrial biogenesis and metabolic hyperactivation limits the application of MTT assay in the estimation of radiation induced growth inhibition. Sci. Rep. 8 (1):1–15. doi:https://doi.org/10.1038/s41598-018-19930-w.
- Reynolds, W. J., P. S. Hanson, A. Critchley, B. Griffiths, B. Chavan, and M. A. Birch-Machin. 2020. Exposing human primary dermal fibroblasts to particulate matter induces changes associated with skin aging. FASEB J. 34 (11):14725–35. doi:https://doi.org/10.1096/fj.202001357R.
- Sahlberg, B., M. Gunnbjörnsdottir, A. Soon, R. Jogi, T. Gislason, G. Wieslander, C. Janson, and D. Norback. 2013. Airborne molds and bacteria, microbial volatile organic compounds (MVOC), plasticizers and formaldehyde in dwellings in three north european cities in relation to sick building syndrome (S.B.S.). Sci. Total Environ. 444:433–40. doi:https://doi.org/10.1016/j.scitotenv.2012.10.114.
- Salminen, T. S., and P. F. Vale. 2020. Drosophila as a model system to investigate the effects of mitochondrial variation on innate immunity. Front Immunol. 11:1–12. doi:https://doi.org/10.3389/fimmu.2020.00521.
- Saraiva, M. A., E. R. Ávila, G. F. da Silva, G. E. Macedo, N. R. Rodrigues, P. B. Vieira, M. S. Nascimento, R. S. Picoloto, I. K. Martins, N. R. de Carvalho, et al. 2018. Exposure of drosophila melanogaster to mancozeb induces oxidative damage and modulates Nrf2 and HSP70/83. Oxid. Med. Cell Long 2018:1–11. doi:https://doi.org/10.1155/2018/5456928.
- Sayan, H. E., and S. Dülger. 2021. Evaluation of the relationship between sick building syndrome complaints among hospital employees and indoor environmental quality. La Medicina del lavoro 112 (2):153–61. doi:https://doi.org/10.23749/mdl.v112i2.11012.
- Shkirkova, K., K. Lamorie-Foote, M. Connor, A. Patel, G. Barisano, H. Baertsch, Q. Liu, T. E. Morgan, C. Sioutas, and W. J. Mack. 2020. Effects of ambient particulate matter on vascular tissue: A review. J. Toxicol. Environ. Health B. 23 (7):319–50. doi:https://doi.org/10.1080/10937404.2020.1822971.
- Somayajulu, M., S. Ekanayaka, S. A. McClellan, D. Bessert, A. Pitchaikannu, K. Zhang, and L. D. Hazlett. 2020. Airborne particulates affect corneal homeostasis and immunity. Invest. Ophthalmol. Vis. Sci. 61 (4):30–32. doi:https://doi.org/10.1167/iovs.61.4.23.
- Stasiv, Y., M. Regulski, B. Kuzin, T. Tully, and G. Enikolopov. 2001. The drosophila nitric-oxide synthase gene (dNOS) encodes a family of proteins that can modulate NOS activity by acting as dominant negative regulators. J. Biol. Chem. 276 (45):42241–51. doi:https://doi.org/10.1074/jbc.M105066200.
- Tashrifi, Z., M. M. Khanaposhtani, B. Larijani, and M. Mahdavi. 2020. DMSO: Yesterday’s solvent, today’s reagent. Adv. Synth. Catal 362 (1):65–86. doi:https://doi.org/10.1002/adsc.201901021.kl.
- Thimmegowda, G. G., S. Mullen, K. Sottilare, A. Sharma, S. S. Mohanta, A. Brockmann, P. S. Dhandapany, and S. B. Olsson. 2020. A field-based quantitative analysis of sublethal effects of air pollution on pollinators. Proc. Natl. Acad. Sci. U.S.A. 117 (34):20653–61. doi:https://doi.org/10.1073/pnas.2009074117.
- Thomson, E. M., D. Breznan, S. Karthikeyan, C. MacKinnon-Roy, N. Q. Vuong, E. Dabek-Zlotorzynska, V. Celo, J.-P. Charland, P. Kumarathasan, J. R. Brook, et al. 2016. Contrasting biological potency of particulate matter collected at sites impacted by distinct industrial sources. Part Fibre Toxicol. 13 (1):1–17. doi:https://doi.org/10.1186/s12989-016-0176-y.
- Tran, V. V., D. Park, and Y.-C. Lee. 2020. Indoor air pollution, related human diseases, and recent trends in the control and improvement of indoor air quality. Int. J. Environ. Res. Public Health 17 (8):1–27. doi:https://doi.org/10.3390/ijerph17082927.
- Tsai, W.-T. 2019. An overview of health hazards of volatile organic compounds regulated as indoors air pollutants. Rev. Environ. Health 34:81–89. doi:https://doi.org/10.1515/reveh-2018-0046.
- Ugur, B., K. Chen, and H. J. Bellen. 2016. Drosophila tools and assays for the study of human diseases. Dis. Model Mech. 9 (3):235–44. doi:https://doi.org/10.1242/dmm.023762.
- Vardoulakis, S., E. Giagloglou, S. Steinle, A. Davis, A. Sleeuwenhoek, K. S. Galea, K. Dixon, and J. O. Crawford. 2020. Indoor exposure to selected air pollutants in the home environment: A systematic review. Int. J. Environ. Res. Public Health 17 (23):1–24. doi:https://doi.org/10.3390/ijerph17238972.
- Viegas, C., M. Almeida-Silva, A. Q. Gomes, H. T. Wolterbeek, and S. M. Almeida. 2014. Fungal contamination assessment in Portuguese elderly care centers. J. Toxicol. Environ. Health Part A 77 (1–3):14–23. doi:https://doi.org/10.1080/15287394.2014.861336.
- Viegas, C., B. Almeida, A. Monteiro, I. Paciência, J. Rufo, L. Aguiar, B. Lage, L. M. D. Gonçalves, L. A. Caetano, E. Carolino, et al. 2020. Exposure assessment in one central hospital: A multi-approach protocol to achieve an accurate risk characterization. Environ. Res. 181. doi:https://doi.org/10.1016/j.envres.2019.108947.
- Wålinder, R., L. Ernstgård, D. Norbäck, G. Wieslander, and G. Johanson. 2008. Acute effects of 1-octen-3-ol, a microbial volatile organic compound (MVOC)—An experimental study. Toxicol. Lett. 181 (3):141–47. doi:https://doi.org/10.1016/j.toxlet.2008.07.013.
- Wang, X., M. Chen, M. Zhong, Z. Hu, L. Qiu, S. Rajagopalan, N. G. Fossett, L. C. Chen, and Z. Ying. 2017. Exposure to concentrated ambient PM2.5 shortens lifespan and induces inflammation-associated signaling and oxidative stress in drosophila. Toxicol. Sci. 156 (1):199–207. doi:https://doi.org/10.1093/toxsci/kfw240.
- West, A. P. 2017. Mitochondrial dysfunction as a trigger of innate immune responses and inflammation. Toxicology 391:54–63. doi:https://doi.org/10.1016/j.tox.2017.07.016.
- WHO. 2014. WHO guidelines for indoor air quality. household fuel combustion. Accessed October 19, 2020. http://apps.who.int/iris/handle/10665/144309/http://apps.who.int//iris/bitstream/10665/141496/1/9789241548885_eng.pdf?ua=1
- Wieslander, G., and D. Norbäck. 2010. Ocular symptoms, tear film stability, nasal patency, and biomarkers in nasal lavage in indoor painters in relation to emissions from water-based paint. Int Arch Occup Environ Health 83 (7):733–41. doi:https://doi.org/10.1007/s00420-010-0552-0.
- Wolkoff, P. 2018. Indoor air humidity, air quality, and health – an overview. Int. J. Hyg. Environ. Health 221 (3):376–90. doi:https://doi.org/10.1016/j.ijheh.2018.01.015.
- Wu, H., L. Lu, J. Chen, C. Zhang, W. Liu, and S. Zhuang. 2020. Inhibited nitric oxide production of human endothelial nitric oxide synthase by nitrated and oxygenated polycyclic aromatic hydrocarbons. Environ. Sci. Technol. 54 (5):2922–30. doi:https://doi.org/10.1021/acs.est.9b07163.
- Yamaguchi, M., and H. Yoshida. 2018. Drosophila as a model organism. In Advances in experimental medicine and biology, ed. W. E. Crusio, H. Dong, H. H. Radeke, N. Rezaei, O. Steinlein, and J. Xiao, 1–10. Cham./CH: Springer Nature Switzerland AG.
- Yin, G., S. Padhi, S. Lee, R. Hung, G. Zhao, and J. W. Bennett. 2015. Effects of three volatile oxylipins on colony development in two species of fungi and on drosophila larval metamorphosis. Curr. Microbiol. 71 (3):347–56. doi:https://doi.org/10.1007/s00284-015-0864-0.
- Zhao, G., G. Yin, A. A. Inamdar, J. Luo, N. Zhang, I. Yang, B. Buckley, and J. W. Bennett. 2017. Volatile organic compounds emitted by filamentous fungi isolated from flooded homes after hurricane sandy show toxicity in a drosophila bioassay. Indoor. Air 27 (3):518–28. doi:https://doi.org/10.1111/ina.12350.
- Zhou, W., X. Yuan, L. Zhang, B. Su, D. Tian, Y. Li, J. Zhao, Y. Wang, and S. Peng. 2017. Overexpression of HO-1 assisted PM2.5-induced apoptosis failure and autophagy-related cell necrosis. Ecotoxicol. Environ. Saf. 145:605–14. doi:https://doi.org/10.1016/j.ecoenv.2017.07.047.