Using native fish in eco-genotoxic assessment of heavy metal contamination pollution arising from nearby large Brazilian rivers

References

• Abidli, A., Y. Huang, Z. Ben Rejeb, A. Zaoui, and C. B. Park. 2022. Sustainable and efficient technologies for removal and recovery of toxic and valuable metals from wastewater: Recent progress, challenges, and future perspectives. Chemosphere 292:133102. doi:10.1016/j.chemosphere.2021.133102.
   PubMed Web of Science ®Google Scholar
• Aich, A., A. R. Goswami, U. S. Roy, and S. K. Mukhopadhyay. 2015. Ecotoxicological assessment of tannery effluent using guppy fish (Poecilia reticulata) as an experimental model: A biomarker study. J. Toxicol. Environ. Health Part A 78 (4):278–86. doi:10.1080/15287394.2014.960045.
   PubMed Web of Science ®Google Scholar
• Al-Sabati, K., and C. D. Metcalfe. 1995. Fish micronuclei for assessing genotoxicity in water. Mutat. Res. 343 (2–3):121–2135. doi:10.1016/0165-1218(95)90078-0.
   PubMed Web of Science ®Google Scholar
• APHA, AWWA, WPCF. 1998. Standard method for examination of water and wastewater. 20th ed. Washington DC: American Public Health Association.
   Google Scholar
• Arruda-Santos, R. H., B. V. M. Costa, P. S. M. Carvalho, and E. Zanardi-Lamardo. 2023. Sewage contamination assessment in an urbanized tropical estuary in Northeast Brazil using elemental, isotopic and molecular proxies. Environ. Pollut. 317:120726. doi:10.1016/j.envpol.2022.120726.
   PubMedGoogle Scholar
• Asllani, F. H., M. Schürz, N. Bresgen, P. M. Eckl, and A. J. Alija. 2019. Genotoxicity risk assessment in fish (Rutilus rutilus) from two contaminated rivers in the Kosovo. Sci. Total Environ. 676:429–35. doi:10.1016/j.scitotenv.2019.04.321.
   PubMed Web of Science ®Google Scholar
• Azqueta, A., and A. R. Collins. 2013. The essential comet assay: A comprehensive guide to measuring DNA damage and repair. Arch. Toxicol. 87 (6):949–68. doi:10.1007/s00204-013-1070-0.
   PubMed Web of Science ®Google Scholar
• Bai, W., Y. Takao, and T. Kubo. 2020. Evaluation of genotoxicity potential of household effluents from onsite wastewater treatment systems using umu test. J. Toxicol. Environ. Health Part A 83 (1):36–44. doi:10.1080/15287394.2020.1719447.
   PubMed Web of Science ®Google Scholar
• Baldissera, M. D., C. F. Souza, D. C. Barroso, R. S. Pereira, K. O. Alessio, C. Bizzi, B. Baldisserotto, and A. L. Val. 2020. Acute exposure to environmentally relevant concentrations of copper affects branchial and hepatic phosphoryl transfer network of Cichlasoma amazonarum: Impacts on bioenergetics homeostasis. Comp. Biochem. Physiol. C Toxicol. Pharmacol. 238:108846. doi:10.1016/j.cbpc.2020.108846.
   PubMed Web of Science ®Google Scholar
• Barbosa, F. 2017. Toxicology of metals and metalloids: Promising issues for future studies in environmental health and toxicology. J. Toxicol. Environ. Health 80 (3):137–44. A. doi:10.1080/15287394.2016.1259475.
   PubMed Web of Science ®Google Scholar
• Baršienė, J., L. Butrimavičienė, W. Grygiel, T. Lang, A. Michailovas, and T. Jackūnas. 2014. Environmental genotoxicity and cytotoxicity in flounder (Platichthys flesus), herring (Clupea harengus) and Atlantic cod (Gadus morhua) from chemical munitions dumping zones in the southern Baltic Sea. Mar. Environ. Res. 96:56–67. doi:10.1016/j.marenvres.2013.08.012.
   PubMed Web of Science ®Google Scholar
• Bianchi, E., T. Dalzochio, L. A. R. Simões, G. Z. P. Rodrigues, C. E. M. Silva, G. Gehlen, C. A. Nascimento, F. R. Spilki, A. L. Ziulkoski, and L. B. Silva. 2019. Water quality monitoring of the Sinos River Basin, Southern Brazil, using physicochemical and microbiological analysis and biomarkers in laboratory-exposed fish. Ecohydrol. Hydrobiol 19 (3):328–33. doi:10.1016/j.ecohyd.2019.05.002.
   Web of Science ®Google Scholar
• Bolognesi, C., and M. Hayashi. 2011. Micronucleus assay in aquatic animals. Mutagenesis 26 (1):205–13. doi:10.1093/mutage/geq073.
   PubMed Web of Science ®Google Scholar
• Brasil. CONAMA. Conselho Nacional do Meio Ambiente. Resolução CONAMA n. 430, de 13 de maio de 2011. Dispõe sobre condições e padrões de lançamento de efluentes, complementa e altera a Resolução no 357, de 17 de março de 2005, do Conselho Nacional do Meio Ambiente - CONAMA. Brasília, 2011. Available in: http://www2.mma.gov.br/port/conama/legiabre.cfm?codlegi=646. Accessed 26 January 2022.
   Google Scholar
• Çakal Arslan, Ö., M. Boyacioğlu, H. Parlak, S. Katalay, and M. A. Karaaslan. 2015. Assessment of micronuclei induction in peripheral blood and gill cells of some fish species from Aliağa Bay Turkey. Mar. Pollut. Bull. 94 (1–2):48–54. doi:10.1016/j.marpolbul.2015.03.018.
   PubMed Web of Science ®Google Scholar
• Campos Júnior, E. O., D. F. Araújo, H. N. Souto, C. F. Campos, and B. B. Pereira. 2020. Contamination and health risks assessment in a dam in the southeast region of Brazil using ecotoxicological methods. J. Toxicol. Environ. Health Part A 83 (10):404–11. doi:10.1080/15287394.2020.1767250.
   PubMed Web of Science ®Google Scholar
• Campos, C. F., S. Morelli, E. O. De Campos Júnior, V. S. V. Santos, C. R. De Morais, M. C. Cunha, H. N. Souto, L. A. Pavanin, A. M. Bonetti, and B. B. Pereira. 2019. Assessment of the genotoxic potential of water courses impacted by wastewater treatment effluents using micronucleus assay in plants from the species Tradescantia. J. Toxicol. Environ. Health Part A 82 (13):752–59. doi:10.1080/15287394.2019.1648345.
   PubMed Web of Science ®Google Scholar
• Campos, E. O., R. G. O. Silva, B. B. Pereira, H. N. Souto, C. F. Campos, J. C. Nepomuceno, and S. Morelli. 2016. Assessment of genotoxic, mutagenic, and recombinogenic potential of water resources in the Paranaíba River basin of Brazil: A case study. J. Toxicol. Environ. Health Part A 79 (24):1190–200. doi:10.1080/15287394.2016.1228490.
   PubMed Web of Science ®Google Scholar
• Çavaş, T., and S. Ergene-gözükara. 2005. Micronucleus test in fish cells: A bioassay for in situ monitoring of genotoxic pollution in the marine environment. Environ. Mol. Mutagen. 46 (1):64–70. doi:10.1002/em.20130.
   PubMed Web of Science ®Google Scholar
• Chagas, T. Q., T. G. da Silva Alvarez, M. F. Montalvão, C. Mesak, T. L. Rocha, A. P. da Costa Araújo, and G. Malafaia. 2019. Behavioral toxicity of tannery effluent in zebrafish (Danio rerio) used as model system. Sci. Total Environ. 685:923–33. doi:10.1016/j.scitotenv.2019.06.253.
   PubMed Web of Science ®Google Scholar
• Costa-Silva, D. G., M. E. Nunes, G. L. Wallau, I. K. Martins, A. P. Zemolin, L. C. Cruz, N. R. Rodrigues, A. R. Lopes, T. Posser, and J. L. Franco. 2015. Oxidative stress markers in fish (Astyanax sp. and Danio rerio) exposed to urban and agricultural effluents in the Brazilian Pampa biome. Environ. Sci. Pollut. Res 22 (20):15526–35. doi:10.1007/s11356-015-4737-7.
   PubMed Web of Science ®Google Scholar
• Da Cuña, R. H., F. L. Lo Nostro, V. Shimabukuro, P. M. Ondarza, and K. S. B. Miglioranza. 2020. Bioaccumulation and distribution behavior of endosulfan on a cichlid fish: Differences between exposure to the active ingredient and a commercial formulation. Environ. Toxicol. Chem. 39 (3):604–11. doi:10.1002/etc.4643.
   PubMed Web of Science ®Google Scholar
• Da Cuña, R. H., M. Pandolfi, G. Genovese, Y. Piazza, M. Ansaldo, and F. L. L. Nostro. 2013. Endocrine disruptive potential of endosulfan on the reproductive axis of Cichlasoma dimerus (Perciformes, Cichlidae). Aquat. Toxicol. 126:299–305. doi:10.1016/j.aquatox.2012.09.015.
   PubMed Web of Science ®Google Scholar
• Da Cuña, R. H., G. R. Vázquez, L. Dorelle, E. M. Rodríguez, R. G. Moreira, and F. L. L. Nostro. 2016. Mechanism of action of endosulfan as disruptor of gonadal steroidogenesis in the cichlid fish Cichlasoma dimerus. Comp. Biochem. Physiol. C Toxicol. Pharmacol. 187:74–80. doi:10.1016/j.cbpc.2016.05.008.
   PubMed Web of Science ®Google Scholar
• D’Agostini, F., and S. La Maestra. 2021. Micronuclei in Fish Erythrocytes as Genotoxic Biomarkers of Water Pollution: An Overview. Rev. Environ. Contam. Toxicol. 258:195–240. doi:10.1007/398_2021_76.
   PubMed Web of Science ®Google Scholar
• De Oliveira, E. C. M., E. S. Caixeta, V. S. V. Santos, and B. B. Pereira. 2021. 2021 arsenic exposure from groundwater: Environmental contamination, human health effects, and sustainable solutions. J. Toxicol. Environ. Health B 24 (3):119–35. doi:10.1080/10937404.2021.1898504.
   PubMed Web of Science ®Google Scholar
• de Paula, A. A., W. E. Risso, and C. B. D. R. Martinez. 2021. Effects of copper on an omnivorous (Astyanax altiparanae) and a carnivorous fish (Hoplias malabaricus): A comparative approach. Aquat. Toxicol. 237:105874. doi:10.1016/j.aquatox.2021.105874.
   PubMed Web of Science ®Google Scholar
• Diehl, K. H., R. Hull, D. Morton, R. Pfister, Y. Rabemampianina, D. Smith, J. M. Vidal, C. van de Vorstenbosch, and European Federation of Pharmaceutical Industries Association and European Centre for the Validation of Alternative Methods. 2001. A good practice guide to the administration of substances and removal of blood, including routes and volumes. J. Appl. Toxicol. 21 (1):15–23. doi:10.1002/jat.727.
   PubMed Web of Science ®Google Scholar
• Dixon, D. R., A. M. Pruski, L. R. Dixon, and A. N. Jha. 2002. Marine invertebrate eco-genotoxicology: A methodological overview. Mutagenesis 17 (6):495–507. doi:10.1093/mutage/17.6.495.
   PubMed Web of Science ®Google Scholar
• Dorelle, L. S., R. H. Cuna, D. E. Sganga, G. R. Vazquez, L. L. N. Greco, and F. L. L. 2020. Fluoxetine exposure disrupts food intake and energy storage in the cichlid fish Cichlasoma dimerus (Teleostei, Chchliformes). Chemosphere 238:124609. doi:10.1016/j.chemosphere.2019.124609.
   PubMed Web of Science ®Google Scholar
• Dos Santos, D. R., F. Y. Yamamoto, F. Filipak Neto, M. A. Randi, J. E. Garcia, D. D. Costa, S. Liebel, S. X. Campos, C. L. Voigt, and C. A. de Oliveira Ribeiro. 2016. The applied indicators of water quality may underestimate the risk of chemical exposure to human population in reservoirs utilized for human supply—southern Brazil. Environ. Sci. Pollut. Res. Int. 23 (10):9625–39. doi:10.1007/s11356-015-5995-0.
   PubMed Web of Science ®Google Scholar
• Eissa, B. L., N. A. Ossana, L. Ferreira, and A. Saliban. 2010. Quantitative behavioral parameters as toxicity biomarkers: Fish responses to waterborne cadmium. Arch. Environ. Contam. Toxicol. 58 (4):1032–39. doi:10.1007/s00244-009-9434-4.
   PubMed Web of Science ®Google Scholar
• Fenech, M. 1997. The advantages and disadvantages of the cytokinesis-block micronucleus method. Mutat. Res. 392 (1–2):11–18. doi:10.1016/s0165-1218(97)00041-4.
   PubMed Web of Science ®Google Scholar
• Ferreira, M. S., M. P. F. Fontes, A. A. Pacheco, H. N. Lima, and J. Z. L. Santos. 2020. Risk assessment of trace element pollution of Manus urban rivers. Sci. Total Environ. 709:134471. doi:10.1016/j.scitotenv.2019.134471.
   PubMed Web of Science ®Google Scholar
• Francisco, C. M., S. M. Bertolino, R. J. De Oliveira Júnior, S. Morelli, and B. B. Pereira. 2019. Genotoxicity assessment of polluted urban streams using a native fish Astyanax altiparanae. J. Toxicol. Environ. Health Part A 82 (8):514–23. doi:10.1080/15287394.2019.1624235.
   PubMed Web of Science ®Google Scholar
• Grisolia, C. K., and F. L. Starling. 2001. Micronuclei monitoring of fishes from Lake Paranoá, under influence of sewage treatment plant discharges. Mutat. Res. 491 (1–2):39–44. doi:10.1016/S1383-5718(00)00168-6.
   PubMed Web of Science ®Google Scholar
• Holland, N., C. Bolognesi, M. Kirsch-Volders, S. Bonassi, E. Zeiger, S. Knasmueller, and M. Fenech. 2008. The micronucleus assay in human buccal cells as a tool for biomonitoring DNA damage: The HUMN project perspective on current status and knowledge gaps. Mutat. Res. 659 (1–2):93–108. doi:10.1016/j.mrrev.2008.03.007.
   PubMed Web of Science ®Google Scholar
• ISO 11466. 1995. Soil Quality e Extraction of Trace Elements Soluble in Aqua Regia. Geneva, Switzerland: International Organization for Standardization.
   Google Scholar
• Kushwaha, B., S. Pandey, S. Sharma, R. Srivastava, R. Kumar, N. S. Nagpure, A. Dabas, and S. Srivastava. 2012. In situ assessment of genotoxic and mutagenic potential of polluted river water in Channa punctatus and Mystus vittatus. Int. Aquat. Res 4 (1):16. doi:10.1186/2008-6970-4-16.
   Google Scholar
• Latif, F., R. Iqbal, F. Ambreen, S. Kousar, T. Ahmed, and S. Aziz. 2024. Studies on bioaccumulation patterns, biochemical and genotoxic effects of copper on freshwater fish Catla catla: An in vivo analysis. Braz. J. Biol. 84:e256905. doi:10.1590/1519-6984.256905.
   Google Scholar
• Lushchak, V. 2016. Contaminant-induced oxidative stress in fish: A mechanistic approach. Fish Physiol. Biochem. 42 (2):711–47. doi:10.1007/s10695-015-0171-5.
   PubMed Web of Science ®Google Scholar
• Madilonga, R. T., J. N. Edokpayi, E. T. Volenzo, O. S. Durowoju, and J. O. Odiyo. 2021. Water quality assessment and evaluation of human health risk in Mutangwi River, Limpopo Province, South Africa. Int. J. Environ. Res. Public Health 24 (13):6765. doi:10.3390/ijerph18136765.
   Google Scholar
• Mahboob, S., H. F. Alkkahem Al-Balwai, F. Al-Misned, K. A. Al-Ghanim, and Z. Ahmad. 2014. A study on the accumulation of nine heavy metals in some important fish species from a natural reservoir in Riyadh, Saudi Arabia. Toxicol. Environ. Chem. 96 (5):783–98. doi:10.1080/02772248.2014.957485.
   Web of Science ®Google Scholar
• Martins, G. C., E. C. Silva Junior, S. J. Ramos, C. W. Maurity, P. K. Sahoo, R. Dall’Agnol, and L. R. G. Guilherme. 2021. Bioavailability of copper and nickel in naturally metal-enriched soils of Carajás Mining Province, Eastern Amazon, Brazil. Environ. Monit. Assess. 193 (5):526. doi:10.1007/s10661-021-09056-4.
   PubMed Web of Science ®Google Scholar
• Maruska, K. P., and R. D. Fernald. 2012. Contextual chemosensory urine signaling in an African cichlid fish. J. Exp. Biol. 215 (1):68–74. doi:10.1242/jeb.062794.
   PubMed Web of Science ®Google Scholar
• Matono, P., T. Batista, E. Sampaio, and M. Ilhéu. 2019. Effects of agricultural land use on the ecohydrology of small- medium Mediterranean River Basins: Insights from a case study in the south of Portugal. Land Use - Assessing the Past, Envisioning the Future. IntechOpen, Ed. 10.5772/intechopen.79756
   Google Scholar
• Matos, L. A., A. C. S. Cunha, A. A. Sousa, J. P. R. Maranhão, N. R. S. Santos, M. M. C. Gonçalves, S. M. M. M. Dantas, J. M. C. E. Sousa, A. P. Peron, F. C. C. D. Silva, et al. 2017. The influence of heavy metals on toxicogenetic damage in a Brazilian tropical river. Chemosphere 185:852–59. doi:10.1016/j.chemosphere.2017.07.103.
   PubMed Web of Science ®Google Scholar
• Meijide, F. J., G. R. Vázquez, Y. G. Piazza, P. A. Babay, R. F. Itria, and F. L. L. Nostro. 2016. Effects of waterborne exposure to 17β-estradiol and 4-tert-octylphenol on early life stages of the South American cichlid fish Cichlasoma dimerus. Ecotoxicol. Environ. Saf. 124:82–90. doi:10.1016/j.ecoenv.2015.10.004.
   PubMed Web of Science ®Google Scholar
• Morais, C. R., S. M. Carvalho, G. R. Araujo, H. N. Souto, A. M. Bonetti, S. Morelli, and E. O. Campos Júnior. 2016. Assessment of water quality and genotoxic impact by toxic metals in Geophagus brasiliensis. Chemosphere 152:328–34. doi:10.1016/j.chemosphere.2016.03.001.
   PubMed Web of Science ®Google Scholar
• Nelson, J. S., T. C. Grande, and M. V. Wilson. 2016. Fishes of the World, p. 752. New Jersey: John Wiley & Sons.
   Google Scholar
• Nemery, B., and C. Banza Lubaba Nkulu. 2018. Assessing exposure to metals using biomonitoring: Achievements and challenges experienced through surveys in low- and middle-income countries. Toxicol. Lett. 298:13–18. doi:10.1016/j.toxlet.2018.06.004.
   PubMed Web of Science ®Google Scholar
• Organization for Economic Cooperation and Development. 1992. Guidelines for the testing of chemicals. In Section 2: Effects on biotic systems. Test number 203, 9. Paris, France: Acute toxicity OECD.
   Google Scholar
• Organization for Economic Cooperation and Development. 2012. Fish Toxicity Testing Framework. OECD Series on Testing and Assessment, No. 171, 174. Paris, France: OECD.
   Google Scholar
• Piazza, Y., M. Pandolfi, R. Da Cuña, G. Genovese, and F. L. Nostro. 2015. Endosulfan affects GnRH cells in sexually differentiated juveniles of the perciform Cichlasoma dimerus. Ecotoxicol. Environ. Saf. 116:150–59. doi:10.1016/j.ecoenv.2015.03.013.
   PubMed Web of Science ®Google Scholar
• Piazza, Y. G., M. Pandolfi, and F. L. L. Nostro. 2011. Effect of the organochlorine pesticide endosulfan on GnRH and gonadotrope cell populations in fish larvae. Arch. Environ. Contam. Toxicol. 61 (2):300–10. doi:10.1007/s00244-010-9621-3.
   PubMed Web of Science ®Google Scholar
• Pollo, F. E., C. L. Bionda, Z. A. Salinas, N. E. Salas, and A. L. Martino. 2015. Common toad Rhinella arenarum (Hensel, 1867) and its importance in assessing environmental health: Test of micronuclei and nuclear abnormalities in erythrocytes. Environ. Monit. Assess. 187 (9):581. doi:10.1007/s10661-015-4802-1.
   PubMed Web of Science ®Google Scholar
• Praveen, N. C., A. Rajesh, M. Madan, V. R. Chaurasia, N. V. Hiremath, and A. M. Sharma. 2014. In vitro evaluation of antibacterial efficacy of pineapple extract (bromelain) on periodontal pathogens. J. Int. Oral Health 6 (5):96–98.
   PubMedGoogle Scholar
• Reyes, E. S., J. J. Aristizabal Henao, K. M. Kornobis, R. M. Hanning, S. E. Majowicz, K. Liber, K. D. Stark, G. Low, H. K. Swanson, and B. D. Laird. 2017. Associations between omega-3 fatty acids, selenium content, and mercury levels in wild-harvested fish from the Dehcho Region, Northwest Territories, Canada. J. Toxicol. Environ. Health Part A 80 (1):18–31. doi:10.1080/15287394.2016.1230916.
   PubMed Web of Science ®Google Scholar
• Sabale, S. R., B. V. Tamhankar, M. M. Dongare, and B. S. Mohite. 2012. Extraction, determination and bioremediation of heavy metal ions and pesticide residues from lake water. J. Bioremed. Biodegrad 3 (04):143. doi:10.4172/2155-6199.1000143.
   Google Scholar
• Schmid, W. 1975. The micronucleus test. Mutat. Res. 1 (1):9–15. doi:10.1016/0165-1161(75)90058-8.
   Google Scholar
• Severo, E. S., A. T. Marins, C. Cerezer, D. Costa, M. Nunes, O. D. Prestes, R. Zanella, and V. L. Loro. 2020. Ecological risk of pesticide contamination in a Brazilian river located near a rural area: A study of biomarkers using zebrafish embryos. Ecotoxicol. Environ. Saf. 190:110071. doi:10.1016/j.ecoenv.2019.110071.
   PubMed Web of Science ®Google Scholar
• Shabbir, Z., A. Sardar, A. Shabbir, G. Abbas, S. Shamshad, S. Khalid, Natasha, G. Murtaza, C. Dumat, and M. Shahid. 2020. Copper uptake, essentiality, toxicity, detoxification and risk assessment in soil-plant environment. Chemosphere 259:127436. doi:10.1016/j.chemosphere.2020.127436.
   PubMed Web of Science ®Google Scholar
• Silva, S. V., A. H. Dias, E. S. Dutra, A. L. Pavanin, S. Morelli, and B. B. Pereira. 2016. The impact of water pollution on fish species in southeast region of Goiás, Brazil. J. Toxicol. Environ. Health Part A 79 (1):8–16. doi:10.1080/15287394.2015.1099484.
   PubMed Web of Science ®Google Scholar
• Singh, M., H. Khan, Y. Verma, and S. V. S. Rana. 2019. Distinctive fingerprints of genotoxicity induced by As, Cr, Cd, and Ni in a freshwater fish. Environ. Sci. Pollut. Res. Int. 26 (19):19445–52. doi:10.1007/s11356-019-05274-z.
   PubMed Web of Science ®Google Scholar
• Sobrino-Figueroa, A. 2018. Toxic effect of commercial detergents on organisms from different trophic levels. Environ. Sci. Pollut. Res 25 (14):13283–91. doi:10.1007/s11356-016-7861-0.
   PubMed Web of Science ®Google Scholar
• Stern, B. R., M. Solioz, D. Krewski, P. Aggett, T. -C. Aw, S. Baker, K. Crump, M. Dourson, L. Haber, R. Hertzberg, et al. 2007. Copper and human health: Biochemistry, genetics, and strategies for modelling dose-response relationships. J. Toxicol. Environ. Health B 10 (3):157–222. doi:10.1080/10937400600755911.
   PubMed Web of Science ®Google Scholar
• Strbac, S., M. Kasanin-Grubin, B. Jovancićevic, and P. Simonovic. 2015. Bioaccumulation of heavy metals and microelements in silver bream (Brama brama L.), northern pike (Esox lucius L.), sterlet (Acipenser ruthenus L.), and common carp (Cyprinus carpio L.) from Tisza River, Serbia. J. Toxicol. Environ. Health Part A 78 (11):663–65. doi:10.1080/15287394.2015.1023406.
   PubMed Web of Science ®Google Scholar
• Tolbert, P. E., C. M. Shy, and J. W. Allen. 1991. Micronuclei and other nuclear anomalies in buccal smears: A field test in snuff users. Am. J. Epidemiol. 134 (8):840–50. doi:10.1093/oxfordjournals.aje.a116159.
   PubMed Web of Science ®Google Scholar
• Udroiu, I., A. Sgura, L. Vignoli, M. A. Bologna, M. D’Amen, D. Salvi, A. Ruzza, A. Antoccia, and C. Tanzarella. 2015. Micronucleus test on Triturus carnifex as a tool for environmental biomonitoring. Environ. Mol. Mutagen. 56 (4):412–17. doi:10.1002/em.21914.
   PubMed Web of Science ®Google Scholar
• Vázquez, G. R., F. J. Meijide, and F. L. Nostro. 2016. Recovery of the reproductive capability following exposure to 4-tert-octylphenol in the neotropical cichlid fish Cichlasoma dimerus. B. Environ. Contam. Toxicol 96 (5):585–90. doi:10.1007/s00128-016-1766-y.
   PubMed Web of Science ®Google Scholar
• Vijitkul, P., M. Kongsema, T. Toommakorn, and V. Bullangpoti. 2022. Investigation of genotoxicity, mutagenicity, and cytotoxicity in erythrocytes of Nile tilapia (Oreochromis niloticus) after fluoxetine exposure. Toxicol. Rep 29:588–96. doi:10.1016/j.toxrep.2022.03.031.
   Google Scholar
• Weber, A. A., C. F. Sales, F. de Souza Faria, R. M. C. Melo, N. Bazzoli, and E. Rizzo. 2020. Effects of metal contamination on liver in two fish species from a highly impacted neotropical river: A case study of the Fundão Dam, Brazil. Ecotoxicol. Environ. Saf. 190:110165. doi:10.1016/j.ecoenv.2020.110165.
   PubMed Web of Science ®Google Scholar
• Winkler, L. W. 1888. Die Bestimmung des im Wasser gelösten Sauerstoffes. Ber. DtschChem. Ges.Ber. DtschChem. Ges. 21 (2):2843–55. doi:10.1002/cber.188802102122.
   Google Scholar
• Xiao, Y., W. J. G. M. Peijnenburg, G. Chen, and M. G. Vijver. 2018. Impact of water chemistry on the particle-specific toxicity of copper nanoparticles to Daphnia magna. Sci. Total Environ. 610-611:1329–35. doi:10.1016/j.scitotenv.2017.08.188.
   PubMed Web of Science ®Google Scholar
• Zebral, Y. D., J. da Silva Fonseca, M. Roza, P. G. Costa, R. B. Robaldo, and A. Bianchini. 2020. Combining elevated temperature with waterborne copper: Impacts on the energy metabolism of the killifish Poecilia vivipara. Chemosphere 253:126631. doi:10.1016/j.chemosphere.2020.126631.
   PubMed Web of Science ®Google Scholar
• Zhong, C. C., T. Zhao, C. Hogstrand, F. Chen, C. C. Song, and Z. Luo. 2022. Copper (Cu) induced changes of lipid metabolism through oxidative stress-mediated autophagy and Nrf2/PPARγ pathways. J. Nutr. Biochem. 100:108883. doi:10.1016/j.jnutbio.2021.108883.
   PubMed Web of Science ®Google Scholar