Sublethal perfluorooctanoic acid and perfluorooctanesulfonic acid delay C. elegans larval development and population growth but do not alter egg hatching

References

• Aljhni, R., F. Ibrahim, Y. C. Guillaume, and C. Andre. 2012. “Reactive Oxygen Species and Nitric Oxide Effect on the Steroid Hormone Binding with Serum Albumin.” Journal of Pharmaceutical and Biomedical Analysis 62:129–134. https://doi.org/10.1016/j.jpba.2011.12.037.
   PubMed Web of Science ®Google Scholar
• Antebi, A. 2013. “Steroid Regulation of C. Elegans Diapause, Developmental Timing, and Longevity.” Current Topics Developmental Biology 105:181–212. https://doi.org/10.1016/B978-0-12-396968-2.00007-5.
   PubMed Web of Science ®Google Scholar
• Apelberg, B. J., F. R. Witter, J. B. Herbstman, A. M. Calafat, R. U. Halden, L. L. Needham, and L. R. Goldman. 2007. “Cord Serum Concentrations of Perfluorooctane Sulfonate (PFOS) and Perfluorooctanoate (PFOA) in Relation to Weight and Size at Birth.” Environmental Health Perspectives 115:1670–1676. https://doi.org/10.1289/ehp.10334.
   PubMed Web of Science ®Google Scholar
• Appel, M., M. Forsthuber, R. Ramos, R. Widhalm, S. Granitzer, M. Uhl, M. Hengstschlager, T. Stamm, and C. Gindacker. 2022. “The Transplacental Transfer Efficiency of Per-And Polyfluoroalkyl Substances (PFAS): A First Meta-Analysis.” Journal of Toxicology and Environmental Health B 25 (1): 23–42. https://doi.org/10.1080/10937404.2021.2009946.
   PubMed Web of Science ®Google Scholar
• Beydoun, S., H. S. Choi, G. Dela-Cruz, J. Kruempel, S. Huang, D. Bazopoulou, H. A. Miller, M. L. Schaller, C. R. Evans, and S. F. Leiser. 2021. “An Alternative Food Source for Metabolism and Longevity Studies in Caenorhabditis Elegans.” Communication Biology 4 (1): 1–9. https://doi.org/10.1038/s42003-021-01764-4.
   PubMed Web of Science ®Google Scholar
• Bonato, M., F. Corra, M. Bellio, L. Guidolin, L. Tallandini, P. Irato, and G. Santovito. 2020. “PFAS Environmental Pollution and Antioxidant Responses: An Overview of the Impact on Human Field.” International Journal of Environment Research & Public Health 17 (21): 8020. https://doi.org/10.3390/ijerph17218020.
   PubMed Web of Science ®Google Scholar
• Brenner, S. 1974. “The Genetics of Caenorhabditis Elegans.” Genetics 77:71–94. https://doi.org/10.1093/genetics/77.1.71.
   PubMed Web of Science ®Google Scholar
• Carvalho, A., S. K. Olson, E. Gutierrez, K. Zhang, L. B. Noble, E. Zanin, A. Desai, A. Groisman, K. Oegema, and B. Lehner. 2011. “Acute Drug Treatment in the Early C. Elegans Embryo.” PLoS One 6 (9): e24656. https://doi.org/10.1371/journal.pone.0024656.
   PubMed Web of Science ®Google Scholar
• Chen, F., C. Wei, Q. Chen, J. Zhang, L. Wang, Z. Zhou, M. Chen, and Y. Liang. 2018. “Internal Concentrations of Perfluorobutane Sulfonate (PFBS) Comparable to Those of Perfluorooctane Sulfonate (PFOS) Induce Reproductive Toxicity in Caenorhabditis Elegans.” Ecotoxicology and Environmental Safety 158:223–229. https://doi.org/10.1016/j.ecoenv.2018.04.032.
   PubMed Web of Science ®Google Scholar
• Coperchini, F., L. Croce, G. Ricci, F. Magri, M. Rotondi, M. Imbrani, and L. Chiovato. 2021. “Thyroid Disrupting Effects of Old and New Generation of PFAS.” Frontiers in Endocrinology 11:612320. https://doi.org/10.3389/fendo.2020.612320.
   PubMed Web of Science ®Google Scholar
• Darbandi, M., S. Darbandi, A. Agarwal, P. Sengupta, D. Durairajanayagam, R. Henkel, and M. R. Sadeghi. 2018. “Reactive Oxygen Species and Male Reproductive Hormones.” Reproductive Biology and Endocrinology 16:87. https://doi.org/10.1186/s12958-018-0406-2.
   PubMed Web of Science ®Google Scholar
• Fei, C., J. K. McLaughlin, R. E. Tarone, and J. Olsen. 2007. “Perfluorinated Chemicals and Fetal Growth: A Study within the Danish National Birth Cohort.” Environmental Health Perspectives 115:1677–1682. https://doi.org/10.1289/ehp.10506.
   PubMed Web of Science ®Google Scholar
• Feng, Z., F. McLamb, J. P. Vu, S. Gong, R. M. Gersberg, and G. Bozinovic. 2022. “Physiological and Transcriptomic Effects of Hexafluoropropylene Oxide Dimer Acid in Caenorhabditis Elegans During Development.” Ecotoxicology Environmental Safety 244:114047. https://doi.org/10.1016/j.ecoenv.2022.114047.
   PubMed Web of Science ®Google Scholar
• Fenton, S. E., A. Ducatman, A. Boobis, J. C. DeWitt, C. Lau, C. Ng, J. S. Smith, and S. M. Roberts. 2021. “Per- and Polyfluoroalkyl Substance Toxicity and Human Health Review: Current State of Knowledge and Strategies for Informing Future Research.” Environmental Toxicology and Chemistry 40 (3): 606–630. https://doi.org/10.1002/etc.4890.
   PubMed Web of Science ®Google Scholar
• Galas, L., E. Raoult, M.-C. Tonon, R. Okada, B. G. Jenks, J. P. Castaño, S. Kikuyama, M. Malagon, E. W. Roubos, and H. Vaudry. 2009. “TRH Acts as a Multifunctional Hypophysiotropic Factor in Vertebrates.” General Comparative Endocrinology 164 (1): 40–50. https://doi.org/10.1016/j.ygcen.2009.05.003.
   PubMed Web of Science ®Google Scholar
• Guo, X., Q. Li, J. Shi, L. Shi, B. Li, A. Xu, G. Zhao, and L. Wu. 2016. “Perfluorooctane Sulfonate Exposure Causes Gonadal Developmental Toxicity in Caenorhabditis Elegans Through ROS-Induced DNA Damage.” Chemosphere 155:115–126. https://doi.org/10.1016/j.chemosphere.2016.04.046.
   PubMed Web of Science ®Google Scholar
• Harlow, P. H., S. J. Perry, S. Widdison, S. Daniels, E. Bondo, C. Lamberth, R. A. Currie, and A. J. Flemming. 2016. “The Nematode Caenorhabditis Elegans as a Tool to Predict Chemical Activity on Mammalian Development and Identify Mechanisms Influencing Toxicological Outcome.” Scientific Reports 6 (1): 22965. https://doi.org/10.1038/srep22965.
   PubMedGoogle Scholar
• Hartman, J. H., S. J. Widmayer, C. M. Bergemann, D. E. King, K. S. Morton, R. F. Romers, L. E. Jameson, et al. 2021. “Xenobiotic Metabolism and Transport in Caenorhabditis Elegans.” Journal of Toxicology and Environmental Health B 24 (2): 51–94. https://doi.org/10.1080/10937404.2021.1884921.
   PubMed Web of Science ®Google Scholar
• Horseman, N. D. 1999. “Prolactin and Mammary Gland Development.” Journal of Mammary Gland Biology Neoplasia 4 (1): 79–88. https://doi.org/10.1023/a:1018708704335.
   PubMed Web of Science ®Google Scholar
• Kaletta, T., and M. O. Hengartner. 2006. “Finding Function in Novel Targets: C. Elegans as a Model Organism.” Nature Review Drug Discovery 5 (5): 387–399. https://doi.org/10.1038/nrd2031.
   PubMed Web of Science ®Google Scholar
• Katiki, L. M., J. F. S. Ferreira, A. M. Zajac, C. Masler, D. S. Lindsay, A. C. S. Chagas, and A. F. T. Amarante. 2011. “Caenorhabditis Elegans as a Model to Screen Plant Extracts and Compounds as Natural Anthelmintics for Veterinary Use.” Veterinary Parasitology 182 (2–4): 264–268. https://doi.org/10.1016/j.vetpar.2011.05.020.
   PubMed Web of Science ®Google Scholar
• Kim, H. M., N. P. Long, S. J. Yoon, N. H. Anh, S. J. Kim, J. H. Park, and S. W. Kwon. 2020. “Omics Approach Reveals Perturbation of Metabolism and Phenotype in Caenorhabditis Elegans Triggered by Perfluorinated Compounds.” Science of the Total Environment 703:135500. https://doi.org/10.1016/j.scitotenv.2019.135500.
   PubMed Web of Science ®Google Scholar
• Kurauchi, M., H. Morise, and T. Eki. 2009. “Using the Nematode Caenorhabditis Elegans Daf-16 Mutant to Assess the Lifespan Toxicity of Prolonged Exposure to Ecotoxic Agents.” Journal of Health Science 55 (5): 796–804. https://doi.org/10.1248/jhs.55.796.
   Google Scholar
• Lažetić, V., and D. S. Fay. 2017. “Molting in C. Elegans.” Worm 6 (1): e1330246. https://doi.org/10.1080/21624054.2017.1330246.
   PubMedGoogle Scholar
• Lee, Y. J., H. W. Jung, H. Y. Kim, Y.-J. Choi, and Y. A. Lee. 2021. “Early-Life Exposure to Per- and Poly-Fluorinated Alkyl Substances and Growth, Adiposity, and Puberty in Children: A Systematic Review.” Frontiers in Endocrinology 12:683297. https://doi.org/10.3389/fendo.2021.683297.
   PubMed Web of Science ®Google Scholar
• Liew, Z., H. Goudarzi, and Y. Oulhote. 2018. “Developmental Exposures to Perfluoroalkyl Substances (PFASs): An Update of Associated Health Outcomes.” Current Environmental Health Report 5 (1): 1–19. https://doi.org/10.1007/s40572-018-0173-4.
   PubMedGoogle Scholar
• Lin, T.-A., C.-W. Huang, and C.-C. Wei. 2022. “Early-Life Perfluorooctanoic Acid (PFOA) and Perfluorooctane Sulfonic Acid (PFOS) Exposure Cause Obesity by Disrupting Fatty Acids Metabolism and Enhancing Triglyceride Synthesis in Caenorhabditis Elegans.” Aquatic Toxicology (Amsterdam, Netherlands) 251:106274. https://doi.org/10.1016/j.aquatox.2022.106274.
   PubMed Web of Science ®Google Scholar
• Liu, G., S. Zhang, K. Yang, L. Zhu, and D. Lin. 2016. “Toxicity of Perfluorooctane Sulfonate and Perfluorooctanoic Acid to Escherichia coli: Membrane Disruption, Oxidative Stress, and DNA Damage Induced Cell Inactivation And/Or Death.” Environmental Pollution 214:806–815. https://doi.org/10.1016/j.envpol.2016.04.089.
   PubMed Web of Science ®Google Scholar
• Panieri, E., K. Baralic, D. Djukic-Cosic, A. Buha Djordjevic, and L. Saso. 2022. “PFAS Molecules: A Major Concern for the Human Health and the Environment.” Toxics 10 (2): 44. https://doi.org/10.3390/toxics10020044.
   PubMed Web of Science ®Google Scholar
• Qian, Y., A. Ducatman, R. Ward, S. Leonard, V. Bukowski, N. Lan Guo, X. Shi, V. Vallyathan, and V. Castranova. 2010. “Perfluorooctane Sulfonate (PFOS) Induces Reactive Oxygen Species (ROS) Production in Human Microvascular Endothelial Cells: Role in Endothelial Permeability.” Journal of Toxicology & Environmental Health A 73 (12): 819–836. https://doi.org/10.1080/15287391003689317.
   PubMed Web of Science ®Google Scholar
• Qi, B., M. Kniazeva, and M. Han. 2017. “A Vitamin-B2-Sensing Mechanism That Regulates Gut Protease Activity to Impact Animal’s Food Behavior and Growth.” ELife 6:e26243. https://doi.org/10.7554/eLife.26243.
   PubMed Web of Science ®Google Scholar
• Ross, I., J. McDonough, J. Miles, P. Storch, P. Thelakkat Kochunarayanan, E. Kalve, J. Hurst, S. S Dasgupta, and J. Burdick. 2018. “A Review of Emerging Technologies for Remediation of PFASs.” Remediation Journal 28 (2): 101–126. https://doi.org/10.1002/rem.21553.
   Web of Science ®Google Scholar
• Sana, T., M. I. Chowdhury, P. Logeshwaran, R. Dharmarajan, and M. Megharaj. 2021. “Perfluorooctanoic Acid (PFOA) Induces Behavioural, Reproductive and Developmental Toxicological Impacts in Caenorhabditis Elegans at Concentrations Relevant to the Contaminated Areas.” Environmental Advances 4:100053. https://doi.org/10.1016/j.envadv.2021.100053.
   Google Scholar
• Steenland, K., and A. Winquist. 2021. “PFAS and Cancer, a Scoping Review of the Epidemiologic Evidence.” Environmental Research 194:110690. https://doi.org/10.1016/j.envres.2020.110690.
   PubMed Web of Science ®Google Scholar
• Stein, C. R., D. A. Savitz, and M. Dougan. 2009. “Serum Levels of Perfluorooctanoic Acid and Perfluorooctane Sulfonate and Pregnancy Outcome.” American Journal of Epidemiology 170 (7): 837–846. https://doi.org/10.1093/aje/kwp212.
   PubMed Web of Science ®Google Scholar
• Suh, K. S., E. M. Choi, Y. J. Kim, S. M. Hong, S. Y. Park, S. Y. Rhee, S. Oh, S. W. Kim, Y. K. Pak, W. Choe, S. Chon. 2017. “Perfluorooctanoic Acid Induces Oxidative Damage and Mitochondrial Dysfunction in Pancreatic β-Cells.” Molecular Medicine Report 15 (6): 3871–3878. https://doi.org/10.3892/mmr.2017.6452.
   PubMed Web of Science ®Google Scholar
• Sumida, C. 1995. “Fatty Acids: Ancestral Ligands and Modern Co-Regulators of the Steroid Hormone Receptor Cell Signalling Pathway.” Prostaglandins, Leukotrienes and Essential Fatty Acids 52 (2–3): 137–144. https://doi.org/10.1016/0952-3278(95)90012-8.
   PubMed Web of Science ®Google Scholar
• Sunderland, E. M., X. Hu, C. Dassincao, A. K. Tokranov, C. C. Wagner, and J. G. Allen. 2019. “A Review of the Pathways of Human Exposure to Polyfluoroalkyl and Perfluoroalkyl acid (PFASs) and Present Understanding of Health Effects.” Journal of Exposure Science Environmental Epidemiology 29 (2): 131–147. https://doi.org/10.1038/s41370-018-0094-1.
   PubMed Web of Science ®Google Scholar
• Tominaga, N., S. Kohra, T. Iguchi, and K. Arizono. 2004. “Effects of Perfluoro Organic Compound Toxicity on Nematode Caenorhabditis Elegans Fecundity.” Journal of Health Science 50 (5): 545–550. https://doi.org/10.1248/jhs.50.545.
   Google Scholar
• Tucker, D. K., M. B. Macon, M. J. Strynar, S. Dagnino, E. Andersen, and S. E. Fenton. 2015. “The Mammary Gland is a Sensitive Pubertal Target in CD-1 and C57Bl/6 Mice Following Perinatal Perfluorooctanoic Acid (PFOA) Exposure.” Reproductive Toxicology 54:26–36. https://doi.org/10.1016/j.reprotox.2014.12.002.
   PubMed Web of Science ®Google Scholar
• USEPA. 2016. Drinking Water Health Advisories for PFOA and PFOS. https://www.epa.gov/sdwa/drinking-water-health-advisories-pfoa-and-pfos
   Google Scholar
• Van Sinay, E., O. Mirabeau, G. Depuydt, M. B. Van Hiel, K. Peymen, J. Watteyne, S. Zels, L. Schoofs, and I. Beets. 2017. “Evolutionarily Conserved TRH Neuropeptide Pathway Regulates Growth in Caenorhabditis Elegans.” Proceedings of the National Academy of Sciences USA 114 (20): E4065–E4074. https://doi.org/10.1073/pnas.1617392114.
   PubMed Web of Science ®Google Scholar
• Wang, W., X. Hong, F. Zhao, J. Wu, and B. Wang. 2022. “The Effects of Perfluoroalkyl and Polyfluoroalkyl Substances on Female Fertility: A Systematic Review and Meta-Analysis.” Environmental Research 209:114718. https://doi.org/10.1016/j.envres.2022.114718.
   Google Scholar
• Wielsøe, M., M. Long, M. Ghisari, and E. C. Bonefeld-Jørgensen. 2015. “Perfluoroalkylated Substances (PFAS) Affect Oxidative Stress Biomarkers in vitro.” Chemosphere 129:239–245. https://doi.org/10.1016/j.chemosphere.2014.10.014.
   PubMed Web of Science ®Google Scholar
• Xiong, H., C. Pears, and A. Woollard. 2017. “An Enhanced C. Elegans Based Platform for Toxicity Assessment.” Scientific Reports 7 (1): 9839. https://doi.org/10.1038/s41598-017-10454-3.
   PubMedGoogle Scholar
• Yin, J., Z. Jian, G. Zhu, X. Yu, Y. Pu, L. Yin, D. Wang, Y. Bu, and R. Liu. 2021. “Male Reproductive Toxicity Involved in Spermatogenesis Induced by Perfluorooctane Sulfonate and Perfluorooctanoic Acid in Caenorhabditis Elegans.” Environment Science Pollution Research 28 (2): 1443–1453. https://doi.org/10.1007/s11356-020-10530-8.
   PubMed Web of Science ®Google Scholar