References
- Ames , B. N. 1971 . “ The detection of chemical mutagens with enteric bacteria ” . In Chemical mutagens; principles and methods for their detection , Edited by: Hollaender , A. vol. 1 , 267 – 287 . New York : Plenum .
- Ames , B. N. , Durston , W. E. , Yamasaki , E. and Lee , F. D. 1973 . Carcinogens are mutagens: A simple test system combining liver homogenates for activation and bacteria for detection . Proc. Nat. Acad. Sci. (U.S.) , 70 : 2281
- Clive , D. , Flamm , W. G. and Machesko , N. 1972 . Mutagenicity of hycanthone in mammalian cells . Mutation Res. , 14 : 262
- da Silva , L. C. , Sette , H. , Chamone , D. , Saez Alquezar , A. , Punskas , J. and Raia , S. 1974 . Clinical trials with oral oxamniquine (UK‐4271) for the treatment of mansonian schistosomiasis . Rev. Inst. Med. Trap. (São Paulo) , 16 : 103
- Foster , R. and Cheetham , B. L. 1973 . Preclinical studies with the schistosomicide oxamniquine (UK‐4271). 1. Activity in rodents and in vitro . Trans. R. Soc. Trop. Med. Hyg. , 67 : 674
- Foster , R. , Cheetham , B. L. and King , D. F. 1973 . Preclinical studies with the schistosomicide oxamniquine (UK‐4271). 2. Activity in primates . Trans. R. Soc. Trop. Med. Hyg. , 67 : 685
- Gabridge , M. G. and Legator , M. S. 1969 . A host‐mediated microbial assay for the detection of mutagenic compounds . Proc. Soc. Exp. Biol. Med. , 130 : 831
- Generoso , W. 1973 . Evaluation of chromosome aberration effects of chemicals on mouse germ cells . Environ. Health Perspect. , 6 : 13 – 22 .
- Green , S. , Carr , J. V. , Sauro , F. M. and Legator , M. S. 1973a . Effects of hycanthone on spermatogonial cells, DNA synthesis in bone marrow and dominant lethality in rats . J. Pharmacol. Exp. Therap. , 187 : 437
- Green , S. , Sauro , F. M. and Legator , M. S. 1973b . Cytogenetic effects of hycanthone in the rat . Mutation Res. , 21 : 52
- Hartman , P. E. , Levine , K. , Hartman , Z. and Berger , H. 1971 . Hycanthone: A frameshift mutagen . Science , 172 : 1058
- Hartman , P. E. , Berger , H. and Hartman , Z. 1973 . Comparison of hycanthone (“Etrenol”), some hycanthone analogs, Myxin and 4‐nitroquinoline‐1‐oxide as frameshift mutagens . J. Pharmacol. Exp. Therap. , 186 : 390
- Hernandez , P. , Dennis , E. W. and Farah , A. 1971 . Metabolism of the schistosomicidal agent hycanthone by rats and rhesus monkeys . Bull. World Health Org. , 45 : 27
- Hirschberg , E. and Weinstein , I. B. 1971 . Comparative ability of hycanthone and Miracil D to interact with DNA . Science , 174 : 1147
- Holden , H. E. , Ray , V. A. , Wahrenburg , M. G. and Zelenski , J. D. 1973 . Mutagenicity studies with 6‐mercaptopurine: 1. Cytogenetic activity in vivo . Mutation Res. , 20 : 257
- Knaap , A. G. A. C. and Kramers , P. G. N. 1973 . Mutagenic effects of hycanthone in . Drosophila melanogaster. Mutation Res. , 21 : 38
- Obe , G. 1973 . Action of hycanthone on human chromosomes in leucocyte cultures . Mutation Res. , 21 : 287
- Ray , V. A. 1973 . Summary of panel on the dominant‐lethal test . Environ. Health Perspect. , 6 : 65 – 66 .
- Ray , V. A. and Hyneck , M. L. 1973 . Some primary considerations in the interpretation of the dominant‐lethal assay . Environ. Health Perspect. , 6 : 27 – 35 .
- Russell , W. Mutagenic studies of hycanthone in mammals . Presented at Environmental Mutagen Society, 5th Annual Meeting . March 8–11 , Washington, D.C..
- Russell , W. L. and Kelly , E. M. 1973 . Ineffectiveness of hycanthone in inducing specific‐locus mutations in mice . Mutation Res. , 21 : 14
- Salsburg , D. S. 1973 . Statistical considerations for dominant lethal mutagenic trials . Environ. Health Perspect. , 6 : 51 – 58 .
- Smith , R. H. 1973 . Lack of mutagenic activity of hycanthone in Habrobracon serinopae females . Mutation Res. , 21 : 279
- Spizizen , J. 1958 . Transformation of biochemically deficient strains of Bacillus subtilis by deoxyribonucleate . Proc. Nat. Acad. Sci. (U.S.) , 44 : 1072
- Von Borstel , R. C. and Quah , S.‐K. 1973 . Induction of mutations in Saccharomyces with hycanthone . Mutation Res. , 21 : 52
- Waring , M. J. 1970 . Variation of the supercoils in closed circular DNA by binding of antibiotics and drugs; evidence for molecular models involving intercalation . J. Mol. Biol. , 54 : 247
- Warren , K. S. 1973 . The pathology of schistosome infections . Helminth. Abst. (Series A) , 42 : 591
- Weiss , L. 1972 . The cells and tissues of the immune system‐structure, functions, interactions , Englewood Cliffs, N.J. : Prentice‐Hall .
- Wright , W. H. 1972 . A consideration of the economic impact of schistosomiasis . Bull. World Health Org. , 47 : 559