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Session 1: Toxicological assay data and the requirements of regulatory agencies: Chairperson: Herbert Blumenthal, Food and Drug Administration

Current problems in the choice of animals for toxicity testing

Pages 9-15 | Published online: 19 Oct 2009

References

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  • Litchfield , J. T. 1961 . Forecasting drug effects in man from studies in laboratory animals . J. Am. Med. Assoc. , 177 : 34
  • Litchfield , J. T. 1962 . Symposium on clinical drug evaluation and human pharmacology . Clin. Pharmacol. Ther. , 3 : 665
  • Salsburg , D. Lifetime carcinogenic studies in rodents, viewed from the standpoint of experimental design—Weaknesses and alternatives . Presented at Royal College of Physicians . December 2 1977 , London.
  • Stevenson , D. E. , Thorpe , E. and Hunt , P. F. The predictive value or otherwise of conventional carcinogenicity studies . Presented at Royal College of Physicians . December 2 1977 , London.

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