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Original Articles

Effect of polybrominated biphenyls on hepatic microsomal metabolism of estrogens and uterotropic action of administered estrogen in rats

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Pages 141-150 | Received 26 Sep 1980, Accepted 13 Jan 1981, Published online: 19 Oct 2009

References

  • Allen , J. R. , Lambrecht , L. K. and Barsotti , D. A. 1978 . Effects of polybrominated biphenyls in nonhuman primates . J. Am. Vet. Med. Assoc. , 173 : 1485 – 1489 .
  • Americ , S. P. , McCormack , K. M. , Braselton , W. E. Jr. and Hook , J. B. 1980 . Altered metabolism of progesterone by hepatic microsomes from rats following dietary exposure to polybrominated biphenyls . Toxicol. Appl. Pharmacol. , 54 : 187 – 196 .
  • Bolt , H. M. 1979 . Effects on endocrine systems by influencing hepatic metabolism of steroid hormones . Pharmacol. Ther. , 5 : 365 – 368 .
  • Bolt , H. M. , Kappus , H. and Bolt , M. 1975 . Effect of rifampicin treatment on the metabolism of oestradiol and 17α‐ethinyloestradiol by human liver microsomes . Eur. J. Clin. Pharmacol. , 8 : 301 – 307 .
  • Breckenridge , A. 1977 . “ Drug interactions with oral contraceptives: An overview ” . In Pharmacology of Steroid Contraceptive Drugs , Edited by: Garattini , S. and Berendes , H. W. 307 – 311 . New York : Raven .
  • Burley , D. M. 1977 . “ Rifampicin, enzyme induction, oestrogens and the pill ” . In Drug Interactions , Edited by: Grahame‐Smith , J. 293 – 299 . London : University Park .
  • Conney , A. H. 1967 . Pharmacological implications of microsomal enzyme induction . Pharmacol. Rey. , 19 : 317 – 366 .
  • Conney , A. H. , Levin , W. , Jacobson , M. and Kuntzman , R. 1973 . Effects of drugs and environmental chemicals on steroid metabolism . Clin. Pharmacol. Ther. , 14 : 727 – 741 .
  • Dent , J. G. , Netter , K. J. and Gibson , J. E. 1976 . The induction of hepatic microsomal metabolism in rats following acute administration of a mixture of polybrominated biphenyls . Toxicol. Appl. Pharmacol. , 38 : 237 – 249 .
  • Dunckel , A. E. 1975 . An updating of the polybrominated biphenyl disaster in Michigan . J. Am. Vet. Med. Assoc. , 167 : 838 – 841 .
  • Harris , S. J. , Cecil , H. C. and Bitman , J. 1978 . Embryotoxic effects of polybrominated biphenyls (PBBs) in rats . Environ. Health Perspect. , 23 : 295 – 300 .
  • Hempel , E. and Klinger , W. 1976 . Drug stimulated biotransformation of hormonal steroid contraceptives: Clinical implications . Drugs , 12 : 442 – 448 .
  • Jackson , T. F. and Halbert , F. S. 1974 . A toxic syndrome associated with the feeding of polybrominated biphenyls contaminated protein concentrate to dairy cattle . J. Am. Vet. Med. Assoc. , 65 : 437 – 439 .
  • Jaraback , J. and Street , A. M. 1971 . The inhibition of the soluble human placental 17ß‐hydroxysteroid dehydrogenase by o,p‐DDT and its analogs . Endocrinology , 89 : 1407 – 1411 .
  • Johnston , C. A. , Demarest , K. T. , McCormack , K. M. , Hook , J. B. and Moore , K. E. 1980 . Endocrinological, neurochemical and anabolic effects of PBBs in male and female rats . Toxlcol. Appl. Pharmacol. , 56 : 240 – 247 .
  • Laegner , H. and Detering , K. 1974 . Anti‐epileptic drugs and failure of oral contraceptives . Lancet , 11 : 600
  • Lambrecht , L. K. , Barsotti , D. A. and Allen , J. R. 1978 . Responses of nonhuman primates to a polybrominated biphenyl mixture . Environ. Health Perspect. , 23 : 139 – 146 .
  • Levin , W. , Welch , R. M. and Conney , A. H. 1968a . Decreased uterotropic potency of oral contraceptives in rats pretreated with phenobarbital . Endocrinology , 83 : 149 – 156 .
  • Levin , W. , Welch , R. M. and Conney , A. H. 1968b . Effect of phenobarbital and other drugs on the metabolism and uterotropic action of estradiol‐17ß and estrone . J. Pharmacol. Exp. Ther. , 159 : 362 – 371 .
  • Lowry , O. H. , Rosebrough , N. J. , Farr , A. E. and Randall , R. J. 1951 . Protein measurement with the Folin phenol reagent . J. Biol. Chem. , 193 : 265 – 275 .
  • McCormack , K. M. , Arneric , S. P. and Hook , J. B. 1979 . Action of exogenously administered steroid hormones following perinatal exposure to polybrominated biphenyls . J. Toxicol. Environ. Health , 5 : 1085 – 1094 .
  • Mester , J. , Robertson , D. M. , Feherty , P. and Kellie , A. E. 1970 . Determination of high‐affinity oestrogen receptor sites in uterine supernatant preparations . Biochem. J. , 120 : 831 – 836 .
  • Munro , H. N. and Fick , A. 1966 . The determination of nucleic acids . Methods Biochem. Anal. , 19 : 113 – 176 .
  • Murad , F. and Gilman , A. G. 1975 . “ Estrogens and progestins ” . In The Pharmacological Basis of Therapeutics , Edited by: Goodman , L. S. and Gilman , A. 1423 – 1450 . New York : Macmillan .
  • Newton , J. F. , Braselton , W. E. , Lepper , L. F. , McCormack , K. M. and Hook , J. B. 1980 . Effects of polybrominated biphenyls (PBBs) on the microsomal metabolism of testosterone . Pharmacologist , 22 : 173
  • Steel , R. G. D. and Torrie , J. H. 1960 . Principles and Procedures of Statistics , New York : McGraw‐Hill .
  • Williams , M. C. and Goldzieher , J. W. 1979 . The metabolism of the ethynyl estrogens. Preparative HPLC profiling of radiolabelled urinary estrogens . Chromatogr. Sci. Ser. , 12 : 395 – 409 .

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