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Original Articles

Electrophysiologic deficits in peripheral nerve as a discriminator of early hexacarbon neurotoxicity

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Pages 835-843 | Received 27 Apr 1983, Accepted 12 Oct 1983, Published online: 20 Oct 2009

References

  • Anderson , R. J. , Parker , J. and Loeb , A. L. 1981 . A microprocessor system for controlling stimulation and on‐line analysis of electrophysiologic parameters . J. Electrophys. Tech. , 7 : 9 – 22 .
  • Averbook , B. J. and Anderson , R. J. 1983 . Electrophysiologic changes associated with chronic administration of organophosphates . Arch. Toxicol. , 52 : 167 – 172 .
  • Billmaier , D. , Yee , H. T. , Allen , N. , Craft , B. , Williams , N. , Epstein , S. and Fontaine , R. 1974 . Peripheral neuropathy in a coated fabrics plant . J. Occup. Med. , 16 : 655 – 671 .
  • Chauplannaz , G. , Bady , B. , Kopp , N. , Levrat , R. and Trillet , M. 1982 . Neuropathie peripherique au n‐hexane chez une toxicomane . Rev. Neurol. (Paris) , 138 : 249 – 257 .
  • Couri , D. and Milks , M. 1982 . Toxicity and metabolism of the neurotoxic hexacarbons n‐hexane, 2‐hexanone, and 2,5‐hexanedione . Ann. Rev. Pharmacol. Toxicol. , 22 : 145 – 166 .
  • Egan , G. , Spencer , P. , Schaumburg , H. , Murray , K. J. , Bischoff , M. and Scala , R. 1980 . N‐Hexane— “Free” hexane mixture fails to produce nervous system damage . Neurotoxicology , 1 : 515 – 524 .
  • Gillies , P. J. , Norton , R. M. , Baker , T. S. and Bus , J. S. 1981 . Altered lipid metabolism in 2,5‐hexane‐dione‐induced testicular atrophy and peripheral neuropathy in the rat . Toxicol. Appl. Pharmacol. , 59 : 293 – 299 .
  • Griffin , J. W. , Price , D. L. and Spencer , P. S. 1977 . Fastaxonal transport through axonal swellings in hexacarbon neuropathy . J. Neuropathology Exp. Neurol. , 36 : 603
  • Loeb , A. L. and Anderson , R. J. 1981 . Antagonism of acrylamide neurotoxicity by supplementation with vitamin B6 . Neurotoxicology , 2 : 625 – 633 .
  • Nachtman , J. P. and Couri , D. 1981 . Biophysical and electrophysical studies of hexanedione neurotoxicity . Neurotoxicology , 2 : 541 – 556 .
  • Ono , Y. , Takeuchi , Y. and Hisanaga , N. 1981 . A comparative study on the toxicity of n‐hexane and its isomers on the peripheral nerve . Int. Arch. Occup. Environ. Health , 48 : 289 – 294 .
  • Ono , Y. , Takeuchi , Y. , Hisanaga , N. , Iwata , M. , Kitoh , J. and Sugiura , Y. 1982 . Neurotoxicity of petroleum benzine compared with n‐hexane . Int. Arch. Occup. Environ. Health , 50 : 219 – 229 .
  • Politis , M. J. , Pellegrino , R. G. and Spencer , P. S. 1980 . Ultrastructural studies of the dying‐back process. V. Axonal neurofilaments accumulate at sties of 2,5‐hexanedione application: Evidence for nerve fibre dysfunction in experimental hexacarbon neuropathy . J. Neurocytol. , 9 : 505 – 516 .
  • Pryor , G. T. , Bingham , L. R. , Dickinson , J. , Rebert , C. S. and Howd , R. A. 1982 . Importance of schedule of exposure to hexane in causing neurotoxicity . Neurobehav. Toxicol. Teratol. , 4 : 71 – 78 .
  • Rebert , C. S. , Houghton , P. W. , Howd , R. A. and Pryor , G. T. 1982 . Effects of hexane on the brain stem auditory response and caudal nerve action potential . Neurobehav. Toxicol. Teratol. , 4 : 79 – 85 .
  • Rizzuto , N. , de Grandis , D. , Di Trapani , G. and Pasinato , E. 1980 . N‐Hexane polyneuropathy. An occupational disease of shoemakers . Eur. Neurol. , 19 : 308 – 315 .
  • Ruff , R. L. , Petito , C. K. and Acheson , L. S. 1981 . Neuropathy associated with chronic low level exposure to n‐hexane . Clin. Toxicol. , 18 : 515 – 519 .
  • Sabri , M. I. and Spencer , P. S. 1979 . Inhibition of glycolysis by chemically unrelated industrial neurotoxins which produce polyneuropathies . Proc. Int. Soc. Neurochem. , 7 : 564
  • Sabri , M. I. , Ederle , K. , Holdsworth , C. E. and Spencer , P. S. 1979a . Studies on the biochemical basis of distal axonopathies. II. Specific inhibition of fructose‐6‐phosphate kinase by 2,5‐hexanedione and methyl n‐butyl ketone . Neurotoxicology , 1 : 285 – 297 .
  • Sabri , M. I. , Moore , C. L. and Spencer , P. S. 1979b . Studies on the biochemical basis of distal axonopathies. I. Inhibition of glyceraldehyde‐3‐phosphate dehydrogenase by neurotoxic hexacarbon compounds . J. Neurochem. , 32 : 683 – 689 .
  • Sahenk , Z. and Mendell , J. R. 1981 . Acrylamide and 2,5‐hexanedione neuropathies: Abnormal bidirectional transport rate in distal axons . Brain Res. , 219 : 397 – 405 .
  • Sanagi , S. , Seki , Y. , Sugimoto , K. and Hirata , M. 1980 . Peripheral nervous system functions of workers exposed to n‐hexane at a low level . Int. Arch. Occup. Environ. Health , 47 : 69 – 79 .
  • Spencer , P. S. and Schaumburg , H. H. 1975 . Experimental neuropathy produced by 2,5‐hexanedione, a major metabolite of the neurotoxic industrial solvent methyl n‐butyl ketone . J. Neurol. Neurosurg. Psychiatry , 38 : 771 – 775 .
  • Spencer , P. S. and Schaumburg , H. H. 1978 . “ The pathobiology of neurotoxic axonal degeneration ” . In Physiology and Pathobiology of Axons , Edited by: Waxman , S. New York : Raven .
  • Spencer , P. S. , Court , D. and Schaumburg , H. H. 1980 . “ N‐Hexane and methyl n‐butyl ketone ” . In Experimental and Clinical Neurotoxicology , Edited by: Spencer , P. S. and Schaumburg , H. H. 456 – 476 . Baltimore : Williams and Wilkins .
  • Sterman , A. B. 1982 . Cell body remodeling during dying‐back axonopathy: DRG changes during advanced disease . J. Neuropathol. Exp. Neurol. , 41 : 400 – 411 .
  • Takeuchi , Y. , Ono , Y. and Hisanaga , N. 1981 . A comparative study of the toxicity of n‐pentane, n‐hexane, and n‐heptane to the peripheral nerve of the rat . Clin. Toxicol. , 18 : 1395 – 1402 .

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