6
Views
11
CrossRef citations to date
0
Altmetric
Original Articles

Cellular distribution of inorganic mercury and its relation to cytotoxicity in bovine kidney cell cultures

, &
Pages 865-877 | Received 06 Jun 1983, Accepted 14 Nov 1983, Published online: 20 Oct 2009

References

  • Bartolome , J. , Criait , E. A. , Trepanier , P. , Whitmore , W. L. , Weigel , S. and Slotkin , T. A. 1982 . Organ specificity of neonatal methyl mercury hydroxide poisoning in the rat: Effects on ornithine decarboxylase activity in developing tissues . Toxicol. Lett. , 13 : 267 – 276 .
  • Bidstrup , P. L. 1972 . Clinical symptoms.of mercury poisoning in man . Biochem. J. , 130 : 59P – 60P .
  • Chang , L. W. 1977 . Neurotoxic effects of mercury—A review . Environ. Res. , 14 : 329 – 373 .
  • Clarkson , T. W. 1972 . The biological properties and distribution of mercury . Biochem. J. , 130 : 61P – 63P .
  • Fang , S. C. and Fallin , E. 1976 . The binding of various mercurial compounds to serum proteins . Bull. Environ. Contam. Toxicol. , 15 : 110 – 117 .
  • Gruenwedel , D. W. , Glaser , J. F. and Cruikshank , M. K. 1981 . Binding of methylmercury (II) by HeLa S3 suspension‐culture cells: Intracellular methylmercury levels and their effect on DNA replication and protein synthesis . Chem. Biol. Interact. , 36 : 259 – 274 .
  • Hammond , P. B. and Bellies , R. P. 1980 . “ Metals ” . In Toxicology: The Basic Science of Poisons , Edited by: Doull , J. , Klaasen , C. D. and Amdur , M. O. 409 – 467 . New York : Macmillan .
  • Imura , N. , Miura , K. , Inokawa , M. and Nakada , S. 1980 . Mechanism of methylmercury cytotoxicity: By biochemical and morphological experiments using cultured cells . Toxicology , 17 : 241 – 254 .
  • Jakubowski , M. , Piotrowski , J. and Trojanowska , B. 1970 . Binding of mercury in the rat: Studies using 203Hg and gel filtration . Toxicol. Appl. Pharmacol. , 16 : 743 – 753 .
  • Kasschau , M. R. and Meyn , R. E. 1981 . Recovery of Chinese hamster cells from mercuric chloride exposure . J. Toxlcol. Environ. Health , 7 : 9 – 18 .
  • Kinter , W. B. and Pritchard , J. B. 1977 . “ Altered permeability of cell membranes ” . In Handbook of Physiology, Section 9: Reactions to Environmental Agents , Edited by: Lee , D. H. K. , Falk , H. L. and Murphy , S. D. 563 – 576 . Bethesda, Md. : American Physiological Society .
  • Massey , T. H. and Fang , S. C. 1968 . A comparative study of the subcellular binding of phenylmercuric acetate and mercuric acetate in rat liver and kidney slices . Toxicol. Appl. Pharmacol. , 12 : 7 – 14 .
  • Nakada , S. and Imura , N. 1980 . Stimulation of DNA synthesis and pyrimidine deoxyribonucleoside transport systems in mouse glioma and mouse neuroblastoma cells by inorganic mercury . Toxicol. Appl. Pharmacol. , 53 : 24 – 28 .
  • Nakada , S. , Nomoto , A. and Imura , N. 1980 . Effect of methylmercury and inorganic mercury on protein synthesis in mammalian cells . Ecotoxicol. Environ. Safety , 4 : 184 – 190 .
  • Nakazawa , N. , Makino , F. and Okada , S. 1975 . Acute effects of mercuric compounds on cultured mammalian cells . Biochem. Pharmacol. , 24 : 489 – 493 .
  • Norseth , T. 1967 . The intracellular distribution of mercury in rat liver after methoxyethylmercury intoxication . Biochem. Pharmacol. , 16 : 1645 – 1654 .
  • Norseth , T. 1968 . The intracellular distribution of mercury in rat liver after a single injection of mercuric chloride . Biochem. Pharmacol. , 17 : 581 – 593 .
  • Oehme , F. 1978 . “ Mechanisms of heavy metal inorganic toxicities ” . In Toxicity of Heavy Metals in the Environment , 69 – 86 . New York : Marcel Dekker . part 1
  • Passow , H. 1970 . “ The red blood cell: Penetration, distribution and toxic actions of heavy metals ” . In Effects of Metals on Ceils, Subcellular Elements and Macromolecules , Edited by: Maniloff , J. , Coleman , J. R. and Miller , M. W. 291 – 345 . Springfield, Ill. : Charles C Thomas .
  • Patterson , M. K. 1979 . Measurement of growth and viability of cells in culture . Methods Enzymol. , 58 : 141 – 152 .
  • Ramanujam , M. , Bondy , S. C. and Prasad , K. N. 1979 . Binding of radioactive methylmercuric chloride in subcellular fractions of neuroblastoma and glioma cells in culture . Toxicol. Lett. , 3 : 265 – 271 .
  • Rothstein , A. 1959 . Cell membrane as site of action of heavy metals . Fed. Proc. , 18 : 1026 – 1038 .
  • Rothstein , A. 1971 . “ Mercaptans, the biological targets for mercurials ” . In Mercury, Mercurials and Mercaptans , Edited by: Miller , M. W. and Clarkson , T. W. 68 – 95 . Springfield, Ill. : Charles C Thomas .
  • Sharma , R. P. and Verma , M. P. 1980 . Metal‐binding proteins in bovine and porcine hepatic and renal tissue: Isolation and characterization . Am. J. Vet. Res. , 41 : 548 – 551 .
  • Stacey , N. H. and Kappus , H. 1982 . Cellular toxicity and lipid peroxidation in response to mercury . Toxicol. Appl. Pharmacol. , 63 : 29 – 35 .
  • Sutherland , R. M. , Rothstein , A. and Weed , R. I. 1967 . Erythrocyte membrane sulfhydryl groups and cation permeability . J. Cell Physiol. , 69 : 185 – 198 .
  • Syversen , T. L. M. 1974 . Distribution of mercury in enzymatically characterized subcellular fractions from the developing rat brain after injections of methylmercuric chloride and diethylmercury . Biochem. Pharmacol. , 23 : 2999 – 3007 .
  • Umeda , M. , Saito , K. , Hirose , K. and Saito , M. 1969 . Cytotoxic effect of inorganic, phenyl and alkyl mercuric compounds on HeLa cells . Jap. J. Exp. Med. , 39 : 47 – 58 .
  • Vallee , B. L. and Ulmer , D. D. 1972 . Biochemical effects of mercury, cadmium and lead . Ann. Rev. Biochem. , 41 : 91 – 128 .
  • Wessel , W. , Georgsson , G. and Segschneider , I. 1969 . Electron‐microscopic studies on the course and effect of high doses of mercuric chloride injected into the renal artery . Virchows Arch. [Zellpathol.] , 3 : 88 – 116 .
  • Yoshino , Y. , Mozai , T. and Nakao , K. 1966 . Distribution of mercury in the brain and its subcellular units in experimental organic mercury poisonings . J. Neurochem , 13 : 397 – 406 .

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.