6
Views
7
CrossRef citations to date
0
Altmetric
Original Articles

Potentiation of 2,6‐dinitrotoluene genotoxicity in fischer 344 rats by pretreatment with coal tar creosote

, , , , , , & show all
Pages 319-336 | Received 15 Apr 1994, Accepted 18 Jul 1994, Published online: 20 Oct 2009

References

  • Chadwick , R. W. , Chang , J. , Forehand , L. R. , Long , J. E. and Duffy , M. C. 1990a . Effect of lindane on intestinal nitroreductase, azo reductase, β‐glucuronidase, dechlorinase, and dehydrochlorinase activity . Pestic. Biochem. Physiol. , 38 : 48 – 56 .
  • Chadwick , R. W. , George , S. E. , Chang , J. , Kohan , M. J. , Dekker , J. P. , Long , J. E. and Duffy , M. C. 1990b . Comparative C.I. enzyme activation of the promutagen 2,6‐dinitrotoluene in male CD‐1 mice and male Fischer 344 rats . Cancer Lett. , 52 : 13 – 19 .
  • Chadwick , R. W. , George , S. E. , Chang , J. , Kohan , M. J. , Dekker , J. P. , Long , J. E. , Duffy , M. C. and Williams , R. W. 1991 . Potentiation of 2,6‐dinitrotoluene genotoxicity in Fischer 344 rats by pre‐treatment with pentachlorophenol . Pestic. Biochem. Physiol. , 39 : 168 – 181 .
  • Chadwick , R. W. , George , S. E. , Kohan , M. J. , Williams , R. W. , Allison , J. C. , Hayes , Y. O. and Chang , J. 1993 . Potentiation of 2,6‐dinitrotoluene genotoxicity in Fischer 344 rats by pretreatment with Aroclor 1254 . Toxicology , 80 : 153 – 171 .
  • Cunningham , M. , Burka , L. T. and Matthews , H. B. 1989 . Metabolism, disposition, and mutagenicity of 2,6‐dinitrotoluene, a mutagenic noncarcinogen. Drug Metafa . Dispos. , 17 : 612 – 617 .
  • DeMarini , D. , Dallas , M. M. and Lewtas , J. 1989 . Cytotoxicity and effect on mutagenicity of buffers in a microsuspension assay . Teratogen. Carcinogen. Mutagen. , 9 : 287 – 295 .
  • Doolittle , D. J. , Sherrill , J. M. and Butterworth , B. E. 1983 . Influence of intestinal bacteria, sex of the animal, and position of the nitro group on the hepatic genotoxicity of nitrotoluene isomers in vivo . Cancer Res. , 43 : 2836 – 2942 .
  • Dybing , E. and Thorgeirsson , S. S. 1977 . Metabolic activation of 2,4‐diaminoanisole, a hair dye component . Biochem. Pharmacol. , 26 : 729 – 734 .
  • Gallagher , J. E. , Jackson , M. H. , George , M. H. , Lewtas , J. and Robertson , I. C. G. 1989 . Differences in detection of DNA adducts 32P‐postlabeling assay after either 1‐butanol or nuclease P1 treatment . Cancer Lett. , 45 : 7 – 12 .
  • George , S. E. , Kohan , M. J. , Walsh , D. B. , Stead , A. G. and Claxton , L. D. 1989 . Polychlorinated biphenyl‐degrading pseudomonads: Survival in mouse intestines and competition with normal flora . J. Toxicol. Environ. Health , 26 : 19 – 37 .
  • George , S. E. , Chadwick , R. W. , Creason , J. P. , Kohan , M. J. and Dekker , J. P. 1991 . Effect of pentachlorophenol on the activation of 2,6‐dinitrotoluene to genotoxic urinary metabolites in CD‐1 Mice: A comparison of Gl enzyme activities and urine mutagenicity . Environ. Mol. Mutagen. , 18 : 92 – 101 .
  • George , S. E. , Chadwick , R. W. , Chang , J. , Kohan , M. J. , Allison , J. C. , Dekker , J. P. and Hayes , Y. 1992 . 2,4,5‐Trichlorophenoxyacetic acid influence on 2,6‐dinitrotoluene‐included urine genotoxicity in Fischer 344 rats: Effect on gastrointestinal microflora and enzyme activity . Fundam. Appl. Toxicol. , 18 : 240 – 246 .
  • Gupta , R. C. , Reddy , M. V. and Randerath , K. 1982 . 32P‐postlabeling analysis of nonradioactive carcino‐gen‐DNA adducts . Carcinogenesis , 3 : 1081 – 1092 .
  • Gupta , R. C. 1984 . Nonrandom binding of the carcinogen, N‐hydroxy‐2‐acetylaminofluorene to repetitive sequences in rat liver DNA in vivo . Proc. Natl Acad. Sci. USA , 81 : 6943 – 6947 .
  • Holdeman , L. , Cato , E. and Moore , W. 1977 . Anaerobe Laboratory Manual , 134 – 140 . Blackburg, Va : Virginia Polytechnic Institute and State University .
  • Lenette , E. H. , Balow , A. , Hauser , W. J. Jr. and Truant , J. P. 1980 . Manual of clinical microbiology , Washington, D.C. : American Society of Microbiology .
  • Leonard , T. B. , Graichen , M. E. and Popp , J. A. 1987 . Dinitrotoluene isomer‐specific hepatocarcinogen‐esis in F344 rats . INCI , 79 : 1313 – 1319 .
  • Long , R. M. and Rickert , D. E. 1982 . Metabolism and excretion of 2,6‐dinitro[14C]toluene in vivo and in isolated perfused rat livers . Drug Metab. Dispos. , 10 : 455 – 458 .
  • Mueller , J. G. , Chapman , P. J. and Pritchard , P. H. 1989 . Creosote‐contaminated sites: Their potential for bioremediation . Environ. Sci. Technol. , 23 : 1197 – 1201 .
  • Reddy , M. V. and Randerath , K. 1986 . Nuclease P1‐mediated enhancement of sensitivity of 32P‐postla‐beling test for structurally diverse DNA adducts . Carcinogenesis , 7 : 1543 – 1551 .
  • Rickert , D. E. , Butterworth , B. E. and Popp , J. A. 1984 . Dinitrotoluene: Acute toxicity, oncogenicity, genotoxicity and metabolism . CRC Crit. Rev. Toxicol. , 13 : 217 – 234 .
  • Schoor , W. P. , Williams , D. E. and Takahashi , N. 1991 . The induction of cytochrome P‐450‐IA1 in juvenile fish by creosote‐contaminated sediment . Arch. Environ. Contam. Toxicol. , 20 : 497 – 504 .
  • Snedecor , G. W. and Cochran , W. G. 1967 . Statistical methods , 59 – 62 . 116 – 118 . Ames : Iowa State University Press .
  • Sutter , V. L. , Citron , D. M. and Finegold , S. M. 1980 . Anaerobic bacteriology manual , St. Louis, Mo. : C. V. Mosby .
  • U.S. Department of Health, Education, and Welfare, Public Health Service, National Institutes of Health . 1980 . “ Bioassay of 2,6‐Diaminotoluene Hydrochloride for Possible Carcinogenicity ” . NCI Carcinogenesis Technical Report Series 200 Springfield, Va : National Technical Information Service (NTIS) . DHEW Publication No. (NIH) 80–1756 (NTIS Accession No. PB80217912)
  • Von Burg , R. and Stout , T. 1992 . Toxicology update . J. Appl. Toxicol. , 12 : 153 – 156 .
  • Watson , W. P. 1987 . Post‐radiolabeling for detecting DNA damage . Mutagenesis , 2 : 319 – 330 .
  • Williams , R. W. , Pasley , T. , Watts , R. , Inman , J. , Fitzgerald , J. and Claxton , L. 1989 . Comparative yields of mutagens from cigarette smokers urine obtained by using solid phase extraction techniques . Environ. Mol. Mutagen. , 14 : 20 – 26 .

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.