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Original Articles

Effects of ozone on the epithelial and inflammatory responses in the airways: Role of tumor necrosis factor

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Pages 329-342 | Received 17 Nov 1994, Accepted 08 Mar 1995, Published online: 20 Oct 2009

References

  • Becker , S. , Madden , M. C. , Newman , S. L. , Devlin , R. B. and Koren , H. S. 1991 . Modulation of human alveolar macrophage properties by ozone exposure in vitro . Toxicol. Appl. Pharmacol. , 110 : 403 – 415 .
  • Bhalla , D. K. and Crocker , T. T. 1987 . Pulmonary epithelial permeability in rats exposed to O3 . J. Toxicol. Environ. Health , 21 : 73 – 87 .
  • Bhalla , D. K. and Young , C. 1992 . Effects of acute exposure to O3 on rats: Sequence of epithelial and inflammatory changes in the distal airways . Inhal. Toxicol. , 4 : 17 – 31 .
  • Bhalla , D. K. , Mannix , R. C. , Kleinman , M. T. and Crocker , T. T. 1986 . Relative permeability of nasal, tracheal, and bronchoalveolar mucosa to macromolecules in rats exposed to ozone . J. Toxicol. Environ. Health , 17 : 269 – 283 .
  • Cybulski , M. I. , Colditz , I. G. and Movat , H. Z. 1986 . The role of interleukin‐1 in neutrophil leukocyte emigration induced by endotoxin . Am. J. Pathol. , 124 : 367 – 372 .
  • Denis , M. , Cormier , Y. , Fournier , M. , Tardif , J. and Laviolette , M. 1991 . Tumor necrosis factor plays an essential role in determining hypersensitivity pneumonitis in a mouse model . Am. J. Respir. Cell Mol. Biol. , 5 : 477 – 483 .
  • Denis , M. , Guejian , L. , Widmer , M. and Cantin , A. 1994 . A mouse model of lung injury induced by microbial products: Implication of tumor necrosis factor . Am. J. Respir. Cell Mol. Biol. , 10 : 658 – 664 .
  • Devlin , R. B. , McDonnell , W. F. , Mann , R. , Becker , S. , House , D. E. , Schreinemachers , D. and Koren , H. S. 1991 . Exposure of humans to ambient levels of ozone for 6.6 hours causes cellular and biochemical changes in the lung . Am. J. Respir. Cell Mol. Biol. , 4 : 72 – 81 .
  • Dinarello , C. A. , Cannon , J. G. , Wolfe , S. M. , Bernheim , H. A. , Beutle , B. , Cerami , A. , Figari , I. S. , Palladino , M. A. and O'Connor , J. V. 1986 . Tumor necrosis factor (cachectin) is an endogenous pyrogen and induces production of interleukin 1 . J. Exp. Med. , 163 : 1433 – 150 .
  • Driscoll , K. E. and Maurer , J. K. 1991 . Cytokine and growth factor release by alveolar macrophages: Potential biomarker of pulmonary toxicity . Toxicol. Pathol. , 19 : 398 – 405 .
  • Driscoll , K. and Schlesinger , R. B. 1988 . Alveolar macrophage‐stimulated neutrophil and monocyte migration: effects of in vitro ozone exposure . Toxicol. Appl. Pharmacol. , 93 : 312 – 318 .
  • Driscoll , K. E. , Lindenschmidt , R. C. , Maurer , J. K. , Higgins , J. M. and Ridder , G. 1990 . Pulmonary response to silica or titanium dioxide: inflammatory cells, alveolar macrophage‐derived cytokines, and histopathology . Am. J. Respir. Cell Mol. Biol. , 2 : 381 – 390 .
  • Driscoll , K. E. , Maurer , J. K. , Poynter , J. , Higgins , J. , Asquith , T. and Miller , N. S. 1992 . Stimulation of rat alveolar macrophage fibronectin release in a cadmium chloride model of lung injury and fibrosis . Toxicol. Appl. Pharmacol. , 116 : 30 – 37 .
  • Esterline , R. L. , Bassett , D. J. P. and Trush , M. A. 1989 . Characterization of the oxidant generation by inflammatory cells lavaged from rat lungs following acute exposure to ozone . Toxicol. Appl. Pharmacol. , 99 : 229 – 239 .
  • Gamble , J. R. , Harlan , J. M. , Klebanoff , S. J. and Vadas , M. A. 1985 . Stimulation of the adherence of neutrophils to umbilical vein endothelium by human recombinant tumor necrosis factor . Proc. Natl. Acad. Sci. USA , 82 : 8667 – 8671 .
  • Hotchkiss , J. A. and Harkema , J. R. 1992 . Endotoxin or cytokines attenuate ozone‐induced DNA synthesis in rat nasal transitional epithelium . Toxicol. Appl. Pharmacol. , 114 : 182 – 187 .
  • Hu , P. C. , Miller , F. J. , Daniels , M. J. , Hatch , G. E. , Graham , J. A. , Gardner , D. E. and Selgrade , M. K. 1982 . Protein accumulation in lung lavage fluid following ozone exposure . Environ. Res. , 29 : 377 – 388 .
  • Jeffes , E. W. B. III , Schmitz , K. , Yamamoto , R. , Tomich , J. M. , Beckman , M. , Nep , R. and Knauer , M. 1991 . A simple nonisotopic in vitro bioassay for LT and TNF employing sodium fluoride‐treated L‐929 target cells that detects picogram quantities of LT and TNF and is as sensitive as TNF assays done with ELISA methodology . Lymphokine Cytokine Res. , 10 : 141 – 145 .
  • Johnson , J. , Meyrick , B. , Jesmok , G. and Brigham , K. L. 1989 . Human recombinant tumor necrosis factor alpha infusion mimics endotoxemia in awake sheep . J. Appl. Physiol. , 66 : 1448 – 1454 .
  • Kehrl , H. R. , Vincent , L. M. , Kowalsky , R. J. , Horstman , D. H. , O'Neil , J. J. , McCartney , W. H. and Bromberg , P. A. 1987 . Ozone exposure increases respiratory epithelial permeability in humans . Am. Rev. Respir. Dis. , 135 : 1124 – 1128 .
  • Kips , J. C. , Tavernier , J. and Pauwels , R. A. 1992 . Tumor necrosis factor causes bronchial hyperresponsiveness in rats . Am. Rev. Respir. Dis. , 145 : 332 – 336 .
  • Klebanoff , S. J. , Vadas , M. A. , Harlan , J. M. , Sparks , L. H. , Gamble , J. R. , Agosti , J. M. and Waltersdorph , A. M. 1986 . Stimulation of neutrophils by tumor necrosis factor . J. Immunol. , 136 : 4220 – 4225 .
  • Koren , H. S. , Devlin , R. B. , Graham , D. E. , Mann , R. , McGee , M. P. , Horstman , D. H. , Kozumbo , W. J. , Becker , S. , House , D. E. , McDonnell , W. F. and Bromberg , P. A. 1989 . Ozone‐induced inflammation in the lower airways of human subjects . Am. Rev. Respir. Dis. , 139 : 407 – 415 .
  • Kreil , E. A. , Greene , E. , Fitzgibbon , C. , Robinson , D. R. and Zapol , W. M. 1989 . Effects of recombinant human tumor necrosis factor alpha, lymphotoxin, and Escherichia coli lipopolysaccharide on hemo‐dynamics, lung microvascular permeability, and eicosanoid synthesis in anesthetized sheep . Cir. Res. , 65 : 502 – 514 .
  • Macy , E. , Kemeny , M. and Saxon , A. 1988 . Enhanced ELISA: How to measure less than 10 picograms of a specific protein (immunoglobulin) in less than 8 hours . FASEB J. , 2 : 3003 – 3009 .
  • Patterson , C. E. , Barnard , J. W. , Lafuze , J. E. , Hull , M. T. , Baldwin , S. J. and Rhoades , R. A. 1989 . The role of activation of neutrophils and microvascular pressure in acute pulmonary edema . Am. Rev. Respir. Dis. , 140 : 1052 – 1062 .
  • Paulesu , L. , Luzzi , E. and Bocci , V. 1991 . Studies on the biological effects of ozone: 2. Induction of tumor necrosis factor (TNF‐α) on human leucocytes . Lymphokine Cytokine Res. , 10 : 409 – 412 .
  • Piguet , P. F. , Collart , M. A. , Grau , G. E. , Sappino , A.‐P. and Vassalli , P. 1990 . Requirement of tumor necrosis factor for development of silica‐induced pulmonary fibrosis . Nature , 344 : 245 – 247 .
  • Pober , J. S. 1988 . “ Mechanisms of action of tumor necrosis factor in vitro: other effects ” . In Tumor necrosis factor/cachectin and related cytokines , Edited by: Bonavida , B. , Gifford , G. E. , Kirchner , H. and Old , L. J. 74 – 81 . Basel : Karger .
  • Pober , J. S. , Gimbrone , M. S. Jr. , Lapierre , L. A. , Mendrick , D. L. , Fiers , W. , Rothlein , R. and Springer , A. 1986 . Overlapping patterns of activation of human endothelial cells by interleukin 1, tumor necrosis factor, and immune interferon . J. Immunol. , 137 : 1893 – 1896 .
  • Pohlman , T. H. , Stanness , K. A. , Beatty , P. G. , Ochs , H. D. and Harlan , J. M. 1986 . An endothelial cell surface factor(s) induced in vitro by lipopolysaccharide, interleukin 1, and tumor necrosis factor‐α increases neutrophil adherence by a CDw18‐dependent mechanism . J. Immunol. , 136 : 4548 – 4553 .
  • Ryan , L. K. and Karol , M. H. 1991 . Release of tumor necrosis factor in guinea pigs upon acute inhalation of cotton dust . Am. J. Respir. Cell Mol. Biol. , 5 : 93 – 98 .
  • Schwerer , B. , Bach , M. and Bernheimer , H. 1987 . ELISA for determination of albumin in the nanogram range: assay in cerebrospinal fluid and comparison with radical immunodiffusion . Clin. Chim. Acta , 163 : 237 – 244 .
  • Seltzer , J. , Bigby , B. G. , Stulbarg , M. , Holtzman , M. J. , Nadel , J. A. , Ueki , I. F. , Leikauf , G. D. , Goetzl , E. J. and Boushey , H. A. 1986 . O3‐induced change in bronchial reactivity to methacholine and airway inflammation in humans . J. Appl. Physiol. , 60 : 1321 – 1326 .
  • Stephens , D. E. , Ishizaka , A. , Wu , Z. , Larrick , J. W. and Raffin , T. A. 1988a . Granulocyte depletion prevents tumor necrosis factor‐mediated acute lung injury in guinea pigs . Am. Rev. Respir. Dis. , 138 : 1300 – 1307 .
  • Stephens , K. E. , Ishizaka , A. , Larrick , J. W. and Raffin , T. A. 1988b . Tumor necrosis factor causes increased pulmonary permeability and edema . Am. Rev. Respir. Dis. , 137 : 1364 – 1370 .
  • Tsujimoto , M. , Yokota , S. , Vilcek , J. and Weissmann , G. 1986 . Tumor necrosis factor provokes super‐oxide anion generation from neutrophils . Biochem. Biophys. Res. Commun. , 137 : 1094 – 1100 .
  • Ulich , T. R. , del Castillo , J. , Keyes , M. , Granger , G. A. and Ni , R.‐X. 1987 . Kinetics and mechanisms of recombinant human interleukin 1 and tumor necrosis factor‐α induced changes in circulating numbers of neutrophils and lymphocytes . J. Immunol. , 139 : 3406 – 3415 .
  • Warren , J. S. and Barton , P. A. 1992 . In vitro analysis of pulmonary inflammation using rat lung organ cultures . Exp. Lung Res. , 18 : 55 – 67 .
  • Warren , J. S. , Yabroff , K. R. , Remick , D. G. , Kunkel , S. L. , Chensue , S. W. , Kunkel , R. G. , Johnson , K. J. and Ward , P. A. 1989 . Tumor necrosis factor participates in the pathogenesis of acute immune complex alveolitis in the rat . J. Clin. Invest. , 84 : 1873 – 1882 .
  • Warren , J. S. , Barton , P. A. , Mandel , D. M. and Matrosic , K. 1990 . Intrapulmonary tumor necrosis factor triggers local platelet‐activating factor production in rat immune complex alveolitis . Lab. Invest. , 63 : 746 – 754 .
  • Weiss , S. J. 1989 . Tissue destruction by neutrophils . N. Engl. J. Med. , 320 : 365 – 376 .
  • Yonemaru , M. , Stephens , K. E. , Ishizaka , A. , Zheng , H. , Hogue , R. S. , Crowley , J. J. , Hatherill , J. R. and Raffin , T. A. 1989 . Effects of tumor necrosis factor on PMN chemotaxis, chemiluminescence, and elastase activity . J. Lab. Clin. Med. , 114 : 674 – 681 .
  • Young , C. and Bhalla , D. K. 1992 . Time course of permeability changes and PMN flux in rat trachea following O3 exposure . Fundam. Appl. Toxicol. , 18 : 175 – 180 .
  • Young , C. , Bhalla , D. K. , Granger , G. A. and Choi , S. S. 1993 . Effects of acute ozone exposure as determined by analysis of bronchoalveolar lavage . Toxicologist , 13 : 296

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