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Articles

Study of leptin gene polymorphism and leptin serum level in alopecia areata patients

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References

  • Alkhalifah, A.; Alsantali, A.; Wang, E.; McElwee, K. J.; Shapiro, J. Alopecia Areata Update: Part I. Clinical Picture, Histopathology, and Pathogenesis. J. Am. Acad. Dermatol. 2010, 62(2), 177–188. DOI: 10.1016/j.jaad.2009.10.032.
  • Xing, L.; Dai, Z.; Jabbari, A.; Cerise, J. E.; Higgins, C. A.; Gong, W.; De Jong, A.; Harel, S.; DeStefano, G. M.; Rothman, L., et al. Alopecia Areata Is Driven by Cytotoxic T Lymphocytes and Is Reversed by JAK Inhibition. Nat. Med. 2014, 20(9), 1043–1049.
  • Poeggeler, B.; Schulz, C.; Pappolla, M. A.; Bodó, E.; Tiede, S.; Lehnert, H.; Paus, R. Leptin and the Skin: A New Frontier. Exp. dermatol. 2010, 19(1), 12–18. DOI: 10.1111/j.1600-0625.2009.00930.x.
  • Carbone, F.; La Rocca, C.; Matarese, G. Immunological Functions of Leptin and Adiponectin. Biochimie. 2012, 94(10), 2082–2088. DOI: 10.1016/j.biochi.2012.05.018.
  • Park, Y. W.; Zhu, S.; Palaniappan, L.; Heshka, S.; Carnethon, M. R.; Heymsfield, S. B. The Metabolic Syndrome: Prevalence and Associated Risk Factor Findings in the US Population from the Third National Health and Nutrition Examination Survey, 1988-1994. Arch.Internal Med. 2003, 163(4), 427–436. DOI: 10.1001/archinte.163.4.427.
  • Otberg, N.; Finner, A. M.; Shaprio, J. Androgenetic Alopecia. Endocrinol. Metab. Clin. North Am. 2007, 36, 379–398. DOI: 10.1016/j.ecl.2007.03.004.
  • Olsen, E. A.; Hordinsky, M. K.; Price, V. H.; Roberts, J. L.; Shapiro, J.; Canfield, D.; Duvic, M.; King, L. E.; McMichael, A. J.; Randall, V. A., et al. Alopecia Areata Investigational Assessment guidelines–Part II. J. Am. Acad. Dermatol. 2004, 51(3), 440–447.
  • Trinder, P. Determination of Glucose in Blood Using Glucose Oxidase with an Alternative Oxygen Acceptor. Ann. Clin. Biochem. 1969, 6(1), 24–27. DOI: 10.1177/000456326900600108.
  • Fossati, P.; Prenciphe, L. Determination of Serum Triglyceride. Clin. Chem. 1982, 28, 207–210.
  • McElwee, K. J.; Gilhar, A.; Tobin, D. J.; Ramot, Y.; Sundberg, J. P.; Nakamura, M.; Bertolini, M.; Inui, S.; Tokura, Y.; King, L. E., et al. What Causes Alopecia Areata? Section Editors: Ralf Paus, Manchester/Lübeck and Raymond Cho, San Francisco. Exp. Dermatol. 2013, 22(9), 609–626.
  • Reis, B. S.; Lee, K.; Fanok, M. H.; Mascaraque, C.; Amoury, M.; Cohn, L. B.; Rogoz, A.; Dallner, O. S.; Moraes-Vieira, P. M.; Domingos, A. I., et al. Leptin Receptor Signaling in T Cells Is Required for Th17 Differentiation. J. Immunol. 2015, 194(11), 5253–5260.
  • Begum, U.; Tursen, U. Autoimmune Skin Diseases and the Metabolic Syndrome. Clinics Dermatol. 2018, 36(1), 67–71. DOI: 10.1016/j.clindermatol.2017.09.012.
  • Medina, G.; Vera-Lastra, O.; Peralta-Amaro, A. L.; Jiménez-Arellano, M. P.; Saavedra, M. A.; Cruz-Domínguez, M. P.; Jara, L. J. Metabolic Syndrome, Autoimmunity and Rheumatic Diseases. Pharmacol. Res. 2018, 133, 277–288. DOI: 10.1016/j.phrs.2018.01.009.
  • Maryam, N.; Safoura, S.; Robabeh, A.; Narges, G.; Zahra, F. A cross-sectional Study of Metabolic Syndrome in Patients with Alopecia Areata. Indian J. Dermatol. Venereol. Leprol. 2021, 87(3), 11–12.
  • Abdollahimajd, F.; Niknezhad, N.; Bahreini, N.; Younespour, S.; Namazi, N. Metabolic Syndrome in Patients with Alopecia Areata: A Case‐control Study. Dermatologic Ther. May 2021, 15, e14979.
  • Anna, S.; Waskiel-Burnatm, S.; Michal, Z.; Adriana, R.; Joanna, C.; Lidia, R. Adiponectin as a Novel Biomarker of Disease Severity in Alopecia Areata. Sci. Rep. 2021, 11(1), 13809. DOI: 10.1038/s41598-021-92853-1.
  • Serarslan, G.; Özcan, O.; Okyay, E.; Ünlü, B.; Karadağ, M. Role of Adiponectin and Leptin in Patients with Alopecia Areata with Scalp Hair Loss. Irish J. Med. Sci. 2021, 190(3), 1015–1020. DOI: 10.1007/s11845-020-02410-4.
  • Banihani, S. A.; Elmadhoun, R. A.; Khabour, O. F.; Alzoubi, K. H. The rs2167270 Polymorphism of Leptin Gene Is Associated with Atopic Dermatitis. Dermato-endocrinology. Jan 1, 2018, 10(1), e1454191. DOI: 10.1080/19381980.2018.1454191.
  • Guo, X.; Roberts, M. R.; Becker, S. M.; Podd, B.; Zhang, Y.; Chua, S. C.; Myers, M. G.; Duggal, P.; Houpt, E. R.; Petri, W. A. Leptin Signaling in Intestinal Epithelium Mediates Resistance to Enteric Infection by Entamoeba Histolytica. Mucosal Immunol. May 2011, 4(3), 294–303. DOI: 10.1038/mi.2010.76.
  • Gualillo, O.; Eiras, S.; Lago, F.; Diéguez, C.; Casanueva, F. F. Elevated Serum Leptin Concentrations Induced by Experimental Acute Inflammation. Life Sci. Oct 6, 2000, 67(20), 2433–2441. DOI: 10.1016/S0024-3205(00)00827-4.
  • Faggioni, R.; Feingold, K. R.; Grunfeld, C. Leptin Regulation of the Immune Response and the Immunodeficiency of Malnutrition 1. FASEB. J. 2001, 15(14), 2565–2571. DOI: 10.1096/fj.01-0431rev.
  • Cava, A. Leptin in Inflammation and Autoimmunity. Cytokine. 2017, 98, 51–58. DOI: 10.1016/j.cyto.2016.10.011.
  • Abdel Hay, R. M.; Rashed, L. A. Association between the Leptin Gene 2548G/A Polymorphism, the Plasma Leptin and the Metabolic Syndrome with Psoriasis. Exp. Dermatol. 2011, 20(9), 715–719. DOI: 10.1111/j.1600-0625.2011.01299.x.
  • Kiguchi, N.; Maeda, T.; Kobayashi, Y.; Fukazawa, Y.; Kishioka, S. Leptin Enhances CC-chemokine Ligand Expression in Cultured Murine Macrophage. Biochem. Biophys. Res. Commun. 2009, 384(3), 311–315. DOI: 10.1016/j.bbrc.2009.04.121.
  • Pratt, C. H.; King, L. E.; Messenger, A. G.; Christiano, A. M.; Sundberg, J. P. Alopecia areata. Nat. Rev. Dis. Primers. 2017, 3(1), 1–7. DOI: 10.1038/nrdp.2017.11.
  • Kirchgessner, T. G.; Uysal, K. T.; Wiesbrock, S. M.; Marino, M. W.; Hotamisligil, G. S. Tumor Necrosis factor-alpha Contributes to obesity-related Hyperleptinemia by Regulating Leptin Release from Adipocytes. J. Clin. Invest. 1997, 100(11), 2777–2782. DOI: 10.1172/JCI119824.
  • Granowitz, E. V. Transforming Growth Factorâ Enhances and pro-inflammatory Cytokines Inhibit OB Gene Expression in 3T3-L1 Adipocytes. Biochem. Biophys. Res. Commun. 1997, 240, 382–385. DOI: 10.1006/bbrc.1997.7663.

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