Advanced search
Publication Cover
Journal of Pain & Palliative Care Pharmacotherapy Volume 32, 2018 - Issue 2-3
Submit an article Journal homepage
835
Views
1
CrossRef citations to date
0
Altmetric
Report

Comparison of haloperidol, non-haloperidol antipsychotics, and no pharmacotherapy for the management of delirium in an inpatient geriatric palliative care population

Maria A. FeltonMedStar Health Department of Medicine, Baltimore, MD, USA; Correspondence[email protected]
View further author information
,
Jennie B. JarrettUniversity of Illinois at Chicago College of Pharmacy, Chicago, IL, USA; View further author information
,
Richard HoffmasterUPMC St. Margaret Department of Medical Education, Pittsburgh,PA, USA; View further author information
,
Frank J. D’AmicoUPMC Palliative and Supportive Institute (PSI), Pittsburgh,PA, USA; View further author information
,
Heather SakelyDepartment of Mathematics and Computer Science at Duquesne University, Pittsburgh, PA, USAView further author information
&
Jennifer PruskowskiUPMC Palliative and Supportive Institute (PSI), Pittsburgh,PA, USA; View further author information
Pages 141-148 | Received 07 Aug 2017, Accepted 13 Aug 2018, Published online: 08 May 2019

References

  • Inouye SK, van Dyck CH, Alessi CA, Balkin S, Siegal AP, Horwitz RI. Clarifying confusion: the confusion assessment method. A new method for detection of delirium. Ann. Intern. Med. 1990;113:941–948.
  • Hosie A, Davidson PM, Agar M, Sanderson CR, Phillips J. Delirium prevalence, incidence, and implications for screening in specialist palliative care inpatient settings: A systematic review. Palliat Med. 2013 Jun;27:486–98.
  • Leslie DL and Inouye SK. The importance of delirium: economic and societal costs. J Am Geriatr Soc. 2011 November;59:S241–S243.
  • McCusker J, Cole M, Abrahamowicz M, Primeau F, Belzile E. Delirium predicts 12-month mortality. Arch Intern Med. 2002 Feb 25;162:457–63.
  • Kiely DK, Marcantonio ER, Inouye SK, et al. Persistent delirium predicts greater mortality. J Am Geriatr Soc. 2009 Jan;57:55–61.
  • McCusker J, Cole M, Dendukuri N, Belzile E. Does delirium increase hospital stay? J Am Geriatr Soc. 1993 Nov;51:1539–46.
  • Better Palliative Care for Older People. World Health Organization. http://www.euro.who.int/__data/assets/pdf_file/0009/98235/E82933.pdf. Updated 2004. Accessed October 1, 2016.
  • Van den Boogaard M, Schoonhoven L, Evers AW, van der Hoeven JG, van Achterberg T, Pickkers P. Delirium in critically ill patients: impact on long-term health-related quality of life and cognitive functioning. Crit Care Med. 2012;40(1):112–118.
  • Alici Y and Breitbart W. Delirium in palliative care. Prim Psychiatry. 2009;16(5):42–48.
  • Rivosecchi RM, Smithburger PL, Svec S, Campbell S, Kane-Gill SL. Nonpharmacological interventions to prevent delirium: an evidence-based systematic review. Crit Care Nurse. 2015 Feb;35(1):39–50.
  • Abraha I, Trotta F, Rimland JM, et al. Efficacy of non-pharmacological interventions to prevent and treat delirium in older patients: a systematic overview. PLoS One. 2015 Jun 10;10(6):e0123090.
  • Hatta K, Kishi Y, Wada K, et al. Antipsychotics for delirium in the general hospital setting in consecutive 2435 inpatients: a prospective observational study. Int J Geriatr Psychiatry. 2014 Mar;29(3):253–262.
  • Herzig SJ, Rothberg MB, Guess JR, et al. Antipsychotic use in hospitalized adults: rates, indications, and predictors. J Am Geriatr Soc. 2016 Feb;64(2):299–305.
  • Grassi L, Caraceni A, Mitchell AJ, et al. Management of delirium in palliative care: a review. Curr Psychiatry Rep. 2015 Mar:17:550.
  • Information for Healthcare Professionals: Conventional Antipsychotics. US Food and Drug Administration. http://www.fda.gov/Drugs/DrugSafety/PostmarketDrugSafetyInformationfor PatientsandProviders/ucm124830.htm. Published June 16, 2008. Updated August 15, 2013. Accessed October 1, 2016.
  • Steinberg M and Lyketsos CG. Atypical antipsychotic use in patients with dementia: managing safety concerns. Am J Psychiatry. 2012 Sept;169:900–906.
  • Garcia C, Lynn R, and Breitbart W. Psychotropic medications in palliative care. Prim Psychiatry. 2009; 16(5):25–32.
  • Miller MO. Evaluation and management of delirium in hospitalized older patients. Am Fam Physician. 2008 Dec;78:1265–1270.
  • Neufeld KJ, Yue U, Robinson TN, Inouye SK, Needham DM. Antipsychotic medication for prevention and treatment of delirium in hospitalized adults: a systematic review and meta-analysis. J Am Geriatr Soc. 2016 Apr;64:705–714.
  • Agar MR, Lawlor PG, Quinn S, et al. Efficacy of oral risperidone, haloperidol, or placebo for symptoms of delirium among patients in palliative Care: A Randomized Clinical Trial. JAMA Intern Med. 2017;177:34–42.
  • The International Classification of Diseases, 9th Revision, Clinical Modification. National Center for Health Statistics (NCHS) and Centers for Medicare & Medicaid Services (CMS). http://icd9cm.chrisendres.com/ Published October 1, 2008. Accessed September 1, 2016.
  • Larsen KA, Kelly SE, Stern TA, et al. Administration of olanzapine to prevent postoperative delirium in elderly joint-replacement patients: A randomized, controlled trial. Psychosomatics 2010;51:409–418.
  • Wensel- Seifert J, Wittmann M, Haen E. QTc prolongation by psychotropic drugs and the risk of Torsade de Pointes. Dtsch Arztebl Int. 2011 Oct;108:687–693.
  • Miller DD. Atypical Antipsychotics: sleep, sedation, and efficacy. Prim Care Companion J Clin Psychiatry. 2004;6(Suppl 2):3–7.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.