A Prospective, Randomized, Double-Blind, Placebo-Controlled Trial to Evaluate Intravenous Acetaminophen Versus Placebo in Patients Undergoing Robotic-Assisted Laparoscopic Prostatectomy

References

• Memis D, Inal MT, Kavalci G, Sezer A, Sut N. Intravenous paracetamol reduced the use of opioids, extubation time, and opioid-related adverse effects after major surgery in intensive care unit. J Crit Care. 2010;25(3):458–62. doi: 10.1016/j.jcrc.2009.12.012.
   PubMed Web of Science ®Google Scholar
• Zhang R, Meng J, Lian Q, Chen X, Bauman B, Chu H, et al. Prescription opioids are associated with higher mortality in patients diagnosed with sepsis: a retrospective cohort study using electronic health records. PLoS One. 2018;13(1):e0190362. doi: 10.1371/journal.pone.0190362.
   PubMed Web of Science ®Google Scholar
• Oderda GM, Said Q, Evans RS, Stoddard GJ, Lloyd J, Jackson K, et al. Opioid-related adverse drug events in surgical hospitalizations: impact on costs and length of stay. Ann Pharmacother. 2007;41(3):400–6. doi: 10.1345/aph.1H386.
   PubMed Web of Science ®Google Scholar
• Trabulsi EJ, Patel J, Viscusi ER, Gomella LG, Lallas CD. Preemptive multimodal pain regimen reduces opioid analgesia for patients undergoing robotic-assisted laparoscopic radical prostatectomy. Urology. 2010;76(5):1122–4. doi: 10.1016/j.urology.2010.03.052.
   PubMed Web of Science ®Google Scholar
• Coluzzi F, Bifulco F, Cuomo A, Dauri M, Leonardi C, Melotti RM, et al. The challenge of perioperative pain management in opioid-tolerant patients. Ther Clin Risk Manag. 2017;13:1163–73. doi: 10.2147/TCRM.S141332.
   PubMed Web of Science ®Google Scholar
• Calcaterra SL, Yamashita TE, Min SJ, Keniston A, Frank JW, Binswanger IA. Opioid prescribing at hospital discharge contributes to chronic opioid use. J Gen Intern Med. 2016;31(5):478–85. doi: 10.1007/s11606-015-3539-4.
   PubMed Web of Science ®Google Scholar
• Pasero C, Stannard D. The role of intravenous acetaminophen in acute pain management: a case-illustrated review. Pain Manag Nurs. 2012;13(2):107–24. doi: 10.1016/j.pmn.2012.03.002.
   PubMed Web of Science ®Google Scholar
• Kolahdouzan K, Eydi M, Mohammadipour Anvari H, Golzari SE, Abri R, Ghojazadeh M, et al. Comparing the efficacy of intravenous acetaminophen and intravenous meperidine in pain relief after outpatient urological surgery. Anesth Pain Med. 2014;4(5):e20337. doi: 10.5812/aapm.20337.
   PubMedGoogle Scholar
• Macario A, Royal MA. A literature review of randomized clinical trials of intravenous acetaminophen (paracetamol) for acute postoperative pain. Pain Pract. 2011;11(3):290–6. doi: 10.1111/j.1533-2500.2010.00426.x.
   PubMed Web of Science ®Google Scholar
• Apfel CC, Turan A, Souza K, Pergolizzi J, Hornuss C. Intravenous acetaminophen reduces postoperative nausea and vomiting: a systematic review and meta-analysis. Pain. 2013;154(5):677–89. doi: 10.1016/j.pain.2012.12.025.
   PubMed Web of Science ®Google Scholar
• Hansen RN, Pham AT, Boing EA, Lovelace B, Wan GJ, Thomas DA, et al. Hospitalization costs and resource allocation in cholecystectomy with use of intravenous versus oral acetaminophen. Curr Med Res Opin. 2018;34(9):1549–1555. doi: 10.1080/03007995.2017.1412301.
   PubMed Web of Science ®Google Scholar
• Hansen RN, Pham AT, Boing EA, Lovelace B, Wan GJ, Miller TE. Comparative analysis of length of stay, hospitalization costs, opioid use, and discharge status among spine surgery patients with postoperative pain management including intravenous versus oral acetaminophen. Curr Med Res Opin. 2017;33(5):943–8. doi: 10.1080/03007995.2017.1297702.
   PubMed Web of Science ®Google Scholar
• Batley SE, Prasad V, Vasdev N, Mohan SG. Post-operative pain management in patients undergoing robotic urological surgery. Curr Urol. 2016;9(1):5–11. doi: 10.1159/000442843. PubMed PMID: 26989364; PubMed Central PMCID: PMCPMC4789944.
   PubMedGoogle Scholar
• Riikonen J, Kaipia A, Petas A, Horte A, Koskimaki J, Kahkonen E, et al. Initiation of robot-assisted radical prostatectomies in Finland: Impact on centralization and quality of care. Scand J Urol. 2016;50(3):149–54. doi: 10.3109/21681805.2016.1142471.
   PubMed Web of Science ®Google Scholar
• Bae J, Kim HC, Hong DM. Intrathecal morphine for postoperative pain control following robot-assisted prostatectomy: a prospective randomized trial. J Anesth. 2017;31(4):565–71. doi: 10.1007/s00540-017-2356-9.
   PubMed Web of Science ®Google Scholar
• Maiti S, Sinvani L, Pisano M, Kozikowski A, Patel V, Akerman M, et al. Opiate prescribing in hospitalized older adults: patterns and outcomes. J Am Geriatr Soc. 2017;66(1):70–75. doi: 10.1111/jgs.15127.
   PubMed Web of Science ®Google Scholar
• Birnbaum HG, White AG, Schiller M, Waldman T, Cleveland JM, Roland CL. Societal costs of prescription opioid abuse, dependence, and misuse in the United States. Pain Med. 2011;12(4):657–67. doi: 10.1111/j.1526-4637.2011.01075.x.
   PubMed Web of Science ®Google Scholar
• American Pain Society. Principles of analgesic use in the treatment of acute pain and cancer pain. Glenview, IL: American Pain Society; 2008.
   Google Scholar
• Aldrete JA. The post-anesthesia recovery score revisited. J Clin Anesth. 1995;7(1):89–91.
   PubMed Web of Science ®Google Scholar
• Maiese BA, Pham AT, Shah MV, Eaddy MT, Lunacsek OE, Wan GJ. Hospitalization costs for patients undergoing orthopedic surgery treated with intravenous acetaminophen (IV-APAP) plus other IV analgesics or IV opioid monotherapy for postoperative pain. Adv Ther. 2017;34(2):421–35. doi: 10.1007/s12325-016-0449-8.
   PubMed Web of Science ®Google Scholar
• Politzer CS, Kildow BJ, Goltz DE, Green CL, Bolognesi MP, Seyler TM. Trends in opioid utilization before and after total knee arthroplasty. J Arthroplasty. 2017;33(7S):S147–S153.e1. doi: 10.1016/j.arth.2017.10.060.
   PubMedGoogle Scholar
• Fenlon S, Collyer J, Giles J, Bidd H, Lees M, Nicholson J, et al. Oral vs intravenous paracetamol for lower third molar extractions under general anaesthesia: is oral administration inferior? Br J Anaesth. 2013;110(3):432–7. doi: 10.1093/bja/aes387.
   PubMed Web of Science ®Google Scholar
• Jahr JS, Filocamo P, Singh S. Intravenous acetaminophen: a review of pharmacoeconomic science for perioperative use. Am J Ther. 2013;20(2):189–99. doi: 10.1097/MJT.0b013e31828900cb.
   PubMed Web of Science ®Google Scholar
• Khosravizadeh O, Vatankhah S, Bastani P, Kalhor R, Alirezaei S, Doosty F. Factors affecting length of stay in teaching hospitals of a middle-income country. Electron Physician. 2016;8(10):3042–7. doi: 10.19082/3042.
   PubMedGoogle Scholar
• Gan TJ, Robinson SB, Oderda GM, Scranton R, Pepin J, Ramamoorthy S. Impact of postsurgical opioid use and ileus on economic outcomes in gastrointestinal surgeries. Curr Med Res Opin. 2015;31(4):677–86. doi: 10.1185/03007995.2015.1005833.
   PubMed Web of Science ®Google Scholar
• Oderda GM, Gan TJ, Johnson BH, Robinson SB. Effect of opioid-related adverse events on outcomes in selected surgical patients. J Pain Palliat Care Pharmacother. 2013;27(1):62–70. doi: 10.3109/15360288.2012.751956.
   PubMedGoogle Scholar
• Pizzi LT, Toner R, Foley K, Thomson E, Chow W, Kim M, et al. Relationship between potential opioid-related adverse effects and hospital length of stay in patients receiving opioids after orthopedic surgery. Pharmacotherapy. 2012;32(6):502–14. doi: 10.1002/j.1875-9114.2012.01101.x.
   PubMed Web of Science ®Google Scholar
• Gulur P, Williams L, Chaudhary S, Koury K, Jaff M. Opioid tolerance—a predictor of increased length of stay and higher readmission rates. Pain Physician. 2014;17(4):E503–7.
   PubMed Web of Science ®Google Scholar