Patient Experiences with Compounded Topical Pain Creams

References

• Gudin JA, Brennan M, Harris E, Hurwitz P, Dietze D, Strader J. Changes in pain and concurrent pain medication use following compounded topical analgesic treatment for chronic pain: 3- and 6-month follow-up results from the prospective, observational Optimizing Patient Experience and Response to Topical Analgesics study. J Pain Res. 2017;10:2341–2354. doi:10.2147/JPR.S143513.
   PubMed Web of Science ®Google Scholar
• Jorge LL, Feres CC, Teles VE. Topical preparations for pain relief: efficacy and patient adherence. J Pain Res. 2010;4:11–24. doi:10.2147/JPR.S9492.
   PubMedGoogle Scholar
• Peppin JF, Albrecht PJ, Argoff C, et al. Skin matters: a review of topical treatments for chronic pain. part one: skin physiology and delivery systems. Pain Ther. 2015;4(1):17–32. doi:10.1007/s40122-015-0031-0.
   PubMed Web of Science ®Google Scholar
• Dailymed. United States National Library of Medicine. https://dailymed.nlm.nih.gov/dailymed/index.cfm. Updated October 28, 2019. Accessed February 4, 2020.
   Google Scholar
• Asbill S, Sweitzer SM, Spigener S, Romero-Sandoval A. Compounded pain formulations: what is the evidence? Int J Pharm Compd. 2014;18(4):278–286.
   PubMedGoogle Scholar
• Cline AE, Turrentine JE. Compounded topical analgesics for chronic pain. Dermatitis. 2016;27(5):263–271. doi:10.1097/DER.0000000000000216.
   PubMed Web of Science ®Google Scholar
• Peppin JF, Albrecht PJ, Argoff C, et al. Skin matters: a review of topical treatments for chronic pain. part two: treatments and applications. Pain Ther. 2015;4(1):33–50. doi:10.1007/s40122-015-0032-z.
   PubMed Web of Science ®Google Scholar
• Boardman LA, Cooper AS, Blais LR, Raker CA. Topical gabapentin in the treatment of localized and generalized vulvodynia. Obstet Gynecol. 2008;112(3):579–585. doi:10.1097/AOG.0b013e3181827c77.
   PubMed Web of Science ®Google Scholar
• Brown S, Erickson B, Muller G, Bryant-Snure SJ, Mestayer RF. Compounded analgesic therapy for disorders of movement: arthritis, neuropathic pain, and postpolio syndrome. Int J Pharm Compd. 2010;14(3):182–192.
   PubMedGoogle Scholar
• Durham MJ, Mekhjian HS, Goad JA, Lou M, Ding M, Richeimer SH. Topical ketamine in the treatment of complex regional pain syndrome. Int J Pharm Compd. 2018;22(2):172–175.
   PubMedGoogle Scholar
• Marshall R, Vidaurri VA, Boomsma D, Buchta AJ, Vail J. Case reports: compounding to relieve arthritis pain. Int J Pharm Compd. 2008;12(6):498–504.
   PubMedGoogle Scholar
• Poterucha TJ, Murphy SL, Rho RH, et al. Topical amitriptyline-ketamine for treatment of rectal, genital, and perineal pain and discomfort. Pain Physician. 2012;15(6):485–488.
   PubMed Web of Science ®Google Scholar
• Poterucha TJ, Murphy SL, Sandroni P, et al. Topical amitriptyline combined with topical ketamine for the management of recalcitrant localized pruritus: a retrospective pilot study. J Am Acad Dermatol. 2013;69(2):320–321. doi:10.1016/j.jaad.2013.03.013.
   PubMed Web of Science ®Google Scholar
• Rabi J, Minori J, Abad H, Lee R, Gittler M. Topical ketamine 10% for neuropathic pain in spinal cord injury patients: an open-label trial. Int J Pharm Compd. 2016;20(6):517–520.
   PubMedGoogle Scholar
• Somberg JC, Molnar J. Retrospective evaluation on the analgesic activities of 2 compounded topical creams and voltaren gel in chronic noncancer pain. Am J Ther. 2015;22(5):342–349. doi:10.1097/MJT.0000000000000275.
   PubMed Web of Science ®Google Scholar
• Tam E, Furlan AD. Transdermal lidocaine and ketamine for neuropathic pain: a study of effectiveness and tolerability. Open Neurol J. 2012;6(1):58–64. doi:10.2174/1874205X01206010058.
   PubMedGoogle Scholar
• Brutcher RE, Kurihara C, Bicket MC, et al. Compounded topical pain creams to treat localized chronic pain: a randomized controlled trial. Ann Intern Med. 2019;170(5):309–318. doi:10.7326/M18-2736.
   PubMed Web of Science ®Google Scholar
• Zugerman JJ, Reed TC. Topical pain relief: assessment of patient satisfaction with a novel compound containing at least ketoprofen. Int J Pharm Compd. 2007;11(6):514–519.
   PubMedGoogle Scholar
• McPherson T, Fontane P, Bilger R. Patient experiences with compounded medications. J Am Pharm Assoc. 2019;59(5):670–677. doi:10.1016/j.japh.2019.05.005.
   Google Scholar
• Barton DL, Wos EJ, Qin R, et al. A double-blind, placebo-controlled trial of a topical treatment for chemotherapy-induced peripheral neuropathy: NCCTG trial N06CA. Support Care Cancer. 2011;19(6):833–841. doi:10.1007/s00520-010-0911-0.
   PubMed Web of Science ®Google Scholar
• Campbell CM, Kipnes MS, Stouch BC, et al. Randomized control trial of topical clonidine for treatment of painful diabetic neuropathy. Pain. 2012;153(9):1815–1823. doi:10.1016/j.pain.2012.04.014.
   PubMed Web of Science ®Google Scholar
• Gerner P, Kao G, Srinivasa V, Narang S, Wang GK. Topical amitriptyline in healthy volunteers. Reg Anesth Pain Med. 2003;28(4):289–293. doi:10.1016/s1098-7339(03)00209-8.
   PubMed Web of Science ®Google Scholar
• Lynch ME, Clark AJ, Sawynok J, Sullivan MJ. Topical 2% amitriptyline and 1% ketamine in neuropathic pain syndromes: a randomized, double-blind, placebo-controlled trial. Anesthesiology. 2005;103(1):140–146. doi:10.1097/00000542-200507000-00021.
   PubMed Web of Science ®Google Scholar
• Mahoney JM, Vardaxis V, Moore JL, Hall A, Haffner KE, Peterson MC. Topical ketamine cream in the treatment of painful diabetic neuropathy: a randomized, placebo-controlled, double-blind initial study. J Am Podiatr Med Assoc. 2012;102(3):178–183. doi:10.7547/1020178.
   PubMed Web of Science ®Google Scholar
• Dailymed. United States National Library of Medicine. https://dailymed.nlm.nih.gov/dailymed/index.cfm. Updated February 21, 2018. Accessed February 4, 2020.
   Google Scholar
• Committee on Advancing Pain Research, Care, and Education, Board on Health Sciences Policy. Institute of Medicine. Relieving pain in America: A blueprint for transforming prevention, care, education, and research. Washington DC, USA: The National Academies Press; 2011.
   Google Scholar
• National academies of science, engineering, and medicine (NASEM) assessment of the available scientific data regarding the safety and effectiveness of ingredients used in compounded topical pain products. United States Food and Drug Administration. https://www.fda.gov/drugs/human-drug-compounding/national-academies-science-engineering-and-medicine-nasem-assessment-available-scientific-data. Published April 19, 2019. Accessed February 4, 2020.
   Google Scholar
• Lin TK, Shoair OA, Tran D, Wilson L. Utilization, cost, and pricing scheme of compounded medications for public health system patients: the California Workers’ Compensation System, 2011-2013. J Manag Care Spec Pharm. 2019;25:743–751. doi:10.18553/jmcp.2019.25.7.743.
   PubMed Web of Science ®Google Scholar
• McPherson T, Fontane P, Iyengar R, Henderson R. Utilization and costs of compounded medications for commercially insured patients, 2012-2013. J Manag Care Spec Pharm. 2016;22:172–181. doi:10.18553/jmcp.2016.22.2.172.
   PubMed Web of Science ®Google Scholar