Coaction of Stress and Serotonin Transporter Genotype in Predicting Aggression at the Transition to Adulthood

REFERENCES

• Achenbach , T. M. ( 1991 ). Manual for the Child Behavior Checklist/ 4–18 and 1991 Profile . Burlington : University of Vermont Department of Psychiatry .
   Google Scholar
• Achenbach , T. M. ( 1997 ). Manual for the Young Adult Self-Report and Young Adult Behavior Checklist . Burlington : University of Vermont Department of Psychiatry .
   Google Scholar
• Attar , B. K. , Guerra , N. G. , & Tolan , P. H. ( 1994 ). Neighborhood disadvantage, stressful life events, and adjustment in urban elementary-school children . Journal of Clinical Child Psychology , 23 , 391 – 400 .
   Web of Science ®Google Scholar
• Beauchaine , T. P. , Klein , D. N. , Crowell , S. E. , Debridge , C. , & Gatzke-Kopp , L. ( 2009 ). Multifinality in the development of personality disorders: A Biology × Sex × Environment interaction model of antisocial and borderline traits . Development and Psychopathology , 21 , 735 – 770 .
   PubMed Web of Science ®Google Scholar
• Beevers , C. G. , Wells , T. T. , Ellis , A. J. , & McGeary , J. E. ( 2009 ). Association of the serotonin transporter gene promoter region (5-HTTLPR) polymorphism with biased attention for emotional stimuli . Journal of Abnormal Psychology , 118 , 670 – 681 .
   PubMed Web of Science ®Google Scholar
• Brown , G. W. , & Harris , T. O. ( 1978 ). Social origins of depression: A study of psychiatric disorder in women . New York : Free Press .
   Google Scholar
• Browne , M. W. , & Cudeck , R. ( 1993 ). Alternative ways of assessing model fit . In K. A. Bollen & J. S. Long (Eds.), Testing structural models (pp. 136 – 162 ). Newbury Park , CA : Sage
   Google Scholar
• Buss , A. H. , & Warren , W. L. ( 2000 ). Aggression Questionnaire . Los Angeles , CA : Psychological Services .
   Google Scholar
• Carver , C. S. , Johnson , S. L. , & Joormann , J. ( 2008 ). Serotonergic function, two-mode models of self-regulation, and vulnerability to depression: What depression has in common with impulsive aggression . Psychological Bulletin , 134 , 912 – 943 .
   PubMed Web of Science ®Google Scholar
• Carver , C. S. , Johnson , S. L. , Joorman , J. , Kim , Y. , & Nam , J. Y. ( 2011 ). Serotonin transporter polymorphism interacts with childhood adversity to predict aspects of impulsivity . Psychological Science , 22 , 589 – 595 . doi: 10.1177/0956797611404085.
   PubMed Web of Science ®Google Scholar
• Caspi , A. C. , McClay , J. , Moffitt , T. E. , Mill , J. , Martin , J. , Craig , I. W. , … Poulton , R. ( 2002 ). Role of genotype in the cycle of violence in maltreated children . Science , 297 , 851 – 854 .
   PubMed Web of Science ®Google Scholar
• Caspi , A. , Sudgen , K. , Moffitt , T. E. , Taylor , A. , Craig , I. W. , … Poulton , R. ( 2003 ). Influence of life stress on depression: moderation by a polymorphism in the 5-HTT gene . Science , 301 , 386 – 389 .
   PubMed Web of Science ®Google Scholar
• Chou , C. P. , & Bentler , P. M. ( 2002 ). Model modification in structural equation modeling by imposing constraints . Computational Statistics & Data Analysis , 41 , 271 – 287 .
   Web of Science ®Google Scholar
• Cicchetti , D. , Rogosch , F. A. , Lynch , M. , & Holt , K. ( 1993 ). Resilience in maltreated children: Processes leading to adaptive outcomes . Development and Psychopathology , 9 , 799 – 817 .
   Google Scholar
• Cicchetti , D. , Rogosch , F. A. , Sturge-Apple , M , & Toth , S. L. ( 2010 ). Interaction of child maltreatment and 5-HTT polymorphisms: Suicidal ideation among children from low-SES backgrounds . Journal of Pediatric Psychology , 35 , 536 – 546 .
   PubMed Web of Science ®Google Scholar
• Conger , R. D. , Ge , X. , Elder , G. H. , Lorenz , F. O. , & Simons , R. L. ( 1994 ). Economic stress, coercive family process, and developmental problems of adolescents . Child Development , 65 , 541 – 561 .
   PubMed Web of Science ®Google Scholar
• Conway , C. C. , Hammen , C. , Espejo , E. P. , Wray , N. R. , Najman , J. M. , & Brennan , P. A. ( 2011 ). Appraisals of stressful life events as a genetically-linked mechanism in the stress-depression relationship. Cognitive Therapy and Research. Advance online publication. doi: 10.1007/s10608-011-9368-9 .
   Google Scholar
• Dodge , K. A. , Bates , J. E. , & Petit , G. S. ( 1990 ). Mechanisms in the cycle of violence . Science , 250 , 1678 – 1683 .
   PubMed Web of Science ®Google Scholar
• Eley , T. C. , Sugden , K. , Corsico , A. , Gregory , A. M. , Sham , P. , McGuffin , P. , … Craig , I. W. ( 2004 ). Gene–environment interaction analysis of serotonin system markers with adolescent depression . Molecular Psychiatry , 9 , 908 – 915 .
   PubMed Web of Science ®Google Scholar
• First , M. B. , Spitzer , R. L. , Gibbon , M. , & Williams , J. B. W. ( 1995 ). Structured clinical Interview for DSM–IV Axis I disorders . Washington , DC : American Psychiatric Press .
   Google Scholar
• Gibb , B. E. , McGeary , J. E. , Beevers , C. G. , & Miller , I. W. ( 2006 ). Serotonin transporter (5-HTTLPR) genotype, child abuse, and suicide attempts in adult psychiatric inpatients . Suicide and Life-Threatening Behavior , 36 , 687 – 693 .
   PubMed Web of Science ®Google Scholar
• Gotlib , I. H. , Joormann , J. , Minor , K. L. , & Hallmayer , J. ( 2008 ). HPA axis reactivity: A mechanism underlying the associations among 5-HTTLPR, stress, and depression . Biological Psychiatry , 63 , 847 – 851 .
   PubMed Web of Science ®Google Scholar
• Grabe , H. J. , Lange , M. , Wolff , B. , Völzke , H. , Lucht , M. , Freyberger , H. J. , … Cascorbi , I. ( 2005 ). Mental and physical distress is modulated by a polymorphism in the 5-HT transporter gene interacting with social stressors and chronic disease burden . Molecular Psychiatry , 10 , 220 – 224 .
   PubMed Web of Science ®Google Scholar
• Gunthert , K. C. , Conner , T. S. , Armeli , S. , Tennen , H. , Covault , J. , & Kranzler , H. R. ( 2007 ). Serotonin transporter gene polymorphism (5-HTTLPR) and anxiety reactivity in daily life: A daily process approach to gene-environment interaction . Psychosomatic Medicine , 69 , 762 – 768 .
   PubMed Web of Science ®Google Scholar
• Hammen , C. , Brennan , P. A. , Keenan-Miller , D. , Hazel , N. A. , & Najman , J. M. ( 2010 ). Chronic and acute stress, gender, and serotonin transporter gene-environment interactions predicting depression symptoms in youth . Journal of Child Psychology and Psychiatry , 51 , 180 – 187 .
   PubMed Web of Science ®Google Scholar
• Hammen , C. , Henry , R. , & Daley , S. (2000). Depression and sensitization to stressors among young women as a function of childhood adversity. Journal of Consulting and Clinical Psychology , 68, 782–787.
   PubMed Web of Science ®Google Scholar
• Hammen , C. L. , Shih , J. H. , Altman , T. , & Brennan , P. A. ( 2003 ). Interpersonal impairment and the prediction of depressive symptoms in adolescent children of depressed and nondepressed mothers . Journal of the American Academy of Child and Adolescent Psychiatry , 42 , 571 – 577 .
   PubMed Web of Science ®Google Scholar
• Hariri , A. R. , Drabant , E. M. , Munoz , K. E. , Kolachana , B. S. , Mattay , V. S. , Egan , M. F. , & Weinberger , D. R. ( 2005 ). A susceptibility gene for affective disorders and the response of the human amygdala . Archives of General Psychiatry , 62 , 146 – 152 .
   PubMed Web of Science ®Google Scholar
• Hariri , A. R. , & Holmes , A. ( 2006 ). Genetics of emotional regulation: The role of the serotonin transporter in neural function . Trends in Cognitive Sciences , 10 , 182 – 191 .
   PubMed Web of Science ®Google Scholar
• Hu , L. , & Bentler , P. M. ( 1999 ). Cutoff criteria for fit indexes in covariance structure analysis: Conventional criteria versus new alternatives . Structural Equation Modeling , 6 , 1 – 55 .
   Web of Science ®Google Scholar
• Hu , X. , Oroszi , G. , Chun , J. , Smith , T. L. , Goldman , D. , & Schuckit , M. A. ( 2004 ). An expanded evaluation of the relationship of four alleles to the level of response to alcohol and the alcoholism risk. Alcoholism Clinical and Experimental Research , 29 , 8 – 16 .
   Web of Science ®Google Scholar
• Karg , K. , Burmeister , M. , Shedden , K. , & Sen , S. ( 2011 ). The serotonin transporter promoter variant (5-HTTLPR), stress, and depression meta-analysis revisited: Evidence of genetic moderation . Archives of General Psychiatry , 68 , 444 – 454 .
   PubMed Web of Science ®Google Scholar
• Keeping , J. D. , Najman , J. M. , Morrison , J. , Western , J. S. , Andersen , M. J. , & Williams , G. M. ( 1989 ). A prospective longitudinal study of social, psychological, and obstetrical factors in pregnancy: Response rates and demographic characteristics of the 8,556 . British Journal of Obstetrics and Gynaecology , 96 , 289 – 297 .
   PubMedGoogle Scholar
• Kendler , K. S. , Kuhn , J. W. , Vittum , J. , Prescott , C. A. , & Riley , B. ( 2005 ). The interaction of stressful life events and a serotonin transporter polymorphism in the prediction of episodes of major depression . Archives of General Psychiatry , 62 , 529 – 535 .
   PubMed Web of Science ®Google Scholar
• Kim-Cohen , J. , Caspi , A. , Tayor , A. , Williams , B. , Newcombe , R. , Craig , I. W. , & Moffitt , T. E. ( 2006 ). MAOA, maltreatment, and gene-environment interaction predicting children's mental health: New evidence and a meta-analysis . Molecular Psychiatry , 11 , 903 – 913 .
   PubMed Web of Science ®Google Scholar
• Koenen , K. C. , Amstadter , A. B. , & Nugent , N. R. ( 2009 ). Gene–environment interaction in posttraumatic stress disorder: An update . Journal of Traumatic Stress , 22 , 416 – 426 .
   PubMed Web of Science ®Google Scholar
• Lesch , K.-P. , Bengel , D. , Heils , A. , Sabol , S. Z. , Greenberg , B. D. , Petri , S. , … Murphy , D. L. ( 1996 ). Association of anxiety-related traits with a polymorphism in the serotonin transporter gene regulatory region . Science , 274 , 1527 – 1531 .
   PubMed Web of Science ®Google Scholar
• Martin , R. , Watson , D. , & Wan , C. K. ( 2000 ). A three-factor model of trait anger: Dimensions of affect, behavior, and cognition . Journal of Personality , 68 , 869 – 897 .
   PubMed Web of Science ®Google Scholar
• Moffitt , T. E. ( 2005 ). The new look of behavior genetics in developmental psychopathology: Gene–Environment interplay in antisocial behaviors . Psychological Bulletin , 131 , 533 – 554 .
   PubMed Web of Science ®Google Scholar
• Monroe , S. M. , & Reid , M. W. ( 2008 ). Gene–environment interactions in depression research. Genetic polymorphisms and life-stress polyprocedures . Psychological Science , 19 , 947 – 956 .
   PubMed Web of Science ®Google Scholar
• Muthén , L. K. , & Muthén , B. O. ( 1998–2007 ). Mplus User's Guide, , 5th edition . Los Angeles, , CA : Author .
   Google Scholar
• Nugent , N. R. , Tyrka , A. R. , Carpenter , L. L. , & Price , L. H. ( 2011 ). Gene–environment interactions: Early life stress and risk for depressive and anxiety disorders . Psychopharmacology , 214 , 175 – 196 .
   PubMed Web of Science ®Google Scholar
• Pezawas , L. , Meyer-Lindenberg , A. , Drabant , E. M. , Verchinski , B. A. , Munoz , K. E. , Kolachana , B. S. , … Weinberger , D. R. ( 2005 ). 5-HTTLPR polymorphism impacts human cingulate-amygdala interactions: A genetic susceptibility mechanism for depression . Nature Neuroscience , 8 , 828 – 834 .
   PubMed Web of Science ®Google Scholar
• Reif , A. , Rosler , M. , Freitag , C. M. , Schneider , M. , Eujen , A. , Kissling , C. , … Retz , W. ( 2007 ). Nature and nurture predispose to violent behavior: Serotonergic genes and adverse childhood environment . Neuropsychopharmacology , 32 , 2375 – 2383 .
   PubMed Web of Science ®Google Scholar
• Risch , N. , Herrell , R. , Lehner , T. , Liang , K.-Y. , Eaves , L. , Hoh , J. , … Merikangas , K. R. ( 2009 ). Interaction between the serotonin transporter gene (5-HTTLPR), stressful life events, and risk of depression . Journal of the American Medical Association , 301 , 2462 – 2471 .
   PubMed Web of Science ®Google Scholar
• Rutter , M. ( 1985 ). Resilience in the face of adversity: Protective factors and resistance to psychiatric disorder . British Journal of Psychiatry , 147 , 598 – 661 .
   PubMed Web of Science ®Google Scholar
• Schafer , J. L. , & Graham , J. W. ( 2002 ). Missing data: Our view of the state of the art . Psychological Methods , 7 , 147 – 177 .
   PubMed Web of Science ®Google Scholar
• Schwandt , M. L. , Lindell , S. G. , Sjoberg , R. L. , Chisholm , K. L. , Higley , J. D. , Suomi , S. J. , … Barr , C. S. ( 2010 ). Gene–environment interactions and response to social intrusion in male and female rhesus macaques . Biological Psychiatry , 67 , 323 – 330 .
   PubMed Web of Science ®Google Scholar
• Sen , S. , Kranzler , H. R. , Krystal , J. H. , Speller , H. , Chan , G. , Gelernter , J. , & Guille , C. ( 2010 ). A prospective cohort study investigating factors associated with depression during medical internship . Archives of General Psychiatry , 67 , 557 – 565 .
   PubMed Web of Science ®Google Scholar
• Siever , L. J. ( 2008 ). Neurobiology of aggression and violence . American Journal of Psychiatry , 165 , 429 – 442 .
   PubMed Web of Science ®Google Scholar
• Sjöberg , R. L. , Nilsson , K. W. , Nordquist , N. , O hrvik , J. , Leppert , J. , Lindström , L. , & Oreland , L. ( 2006 ). Development of depression: Sex and the interaction between environment and a promoter polymorphism of the serotonin transporter gene . International Journal of Neuropsychopharmacology , 9 , 443 – 449 .
   PubMed Web of Science ®Google Scholar
• Stein , M. B. , Schork , N. J. , & Gelernter , J. ( 2008 ). Gene-by-environment (serotonin transporter and childhood maltreatment) interaction for anxiety sensitivity, an intermediate phenotype for anxiety disorders . Neuropsychopharmacology , 33 , 312 – 319 .
   PubMed Web of Science ®Google Scholar
• Uher , R. , & McGuffin , P. ( 2008 ). The moderation by the serotonin transporter gene of environmental adversity in the etiology of mental illness: Review and methodological analysis . Molecular Psychiatry , 13 , 131 – 146 .
   PubMed Web of Science ®Google Scholar
• Verona , E. , Joiner , T. E. , Johnson , F. , & Bender , T. W. ( 2006 ). Gender specific gene–environment interactions on laboratory-assessed aggression . Biological Psychology , 71 , 33 – 41 .
   PubMed Web of Science ®Google Scholar
• Way , B. M. , & Taylor , S. E. ( 2010 ). The serotonin transporter promoter polymorphism is associated with cortisol response to psychosocial stress . Biological Psychiatry , 67 , 487 – 492 .
   PubMed Web of Science ®Google Scholar
• Wray , N. R. , James , M. R. , Gordon , S. D. , Dumenil , T. , Ryan , L. , & Coventry , W. L. ( 2009 ). Accurate, large-scale genotyping of 5HTTLPR and flanking single nucleotide polymorphisms in an association study of depression, anxiety, and personality measures . Biological Psychiatry , 66 , 468 – 476 .
   PubMed Web of Science ®Google Scholar