122
Views
7
CrossRef citations to date
0
Altmetric
Research Article

An investigation of the developmental neurotoxic potential of curcumol in PC12 cells

, &
Pages 635-643 | Received 09 May 2016, Accepted 26 Jun 2016, Published online: 06 Nov 2016

References

  • Ansari RW, Shukla RK, Yadav RS, et al. (2012). Cholinergic dysfunctions and enhanced oxidative stress in the neurobehavioral toxicity of lambda-cyhalothrin in developing rats. Neurotox Res 22:292–309.
  • Ayyappan P, Palayyan SR, Kozhiparambil Gopalan R. (2016). Attenuation of oxidative damage by Boerhaavia diffusa L. against different neurotoxic agents in rat brain homogenate. J Diet Suppl 13:300–12.
  • Bisaz R, Conboy L, Sandi C. (2009). Learning under stress: a role for the neural cell adhesion molecule NCAM. Neurobiol Learn Mem 91:333–42.
  • Bromberg KD, Iyengar R, He JC. (2008). Regulation of neurite outgrowth by G(i/o) signaling pathways. Front Biosci 13:4544–57.
  • Chen J, Liufu C, Sun W, et al. (2010). Assessment of the neurotoxic mechanisms of decabrominated diphenyl ether (PBDE-209) in primary cultured neonatal rat hippocampal neurons includes alterations in second messenger signaling and oxidative stress. Toxicol Lett 192:431–9.
  • Cordova FM, Aguiar AS, Jr., Peres TV, et al. (2013). Manganese-exposed developing rats display motor deficits and striatal oxidative stress that are reversed by Trolox. Arch Toxicol 87:1231–44.
  • Culbreth ME, Harrill JA, Freudenrich TM, et al. (2012). Comparison of chemical-induced changes in proliferation and apoptosis in human and mouse neuroprogenitor cells. Neurotoxicology 33:1499–510.
  • Ding J, Wang JJ, Huang C, et al. (2014). Curcumol from Rhizoma Curcumae suppresses epileptic seizure by facilitation of GABA(A) receptors. Neuropharmacology 81:244–55.
  • Dityatev A, Dityateva G, Sytnyk V, et al. (2004). Polysialylated neural cell adhesion molecule promotes remodeling and formation of hippocampal synapses. J Neurosci 24:9372–82.
  • Dribben WH, Creeley CE, Farber N. (2011). Low-level lead exposure triggers neuronal apoptosis in the developing mouse brain. Neurotoxicol Teratol 33:473–80.
  • Dubovický M, Kovačovský P, Ujházy E, et al. (2008). Evaluation of developmental neurotoxicity: some important issues focused on neurobehavioral development. Interdiscip Toxicol 1:206–10.
  • Duran EM, Shapshak P, Worley J, et al. (2005). Presenilin-1 detection in brain neurons and FOXP3 in peripheral blood mononuclear cells: normalizer gene selection for real time reverse transcriptase pcr using the deltadeltaCt method. Front Biosci 10:2955–65.
  • Fujita-Hamabe W, Tokuyama S. (2012). The involvement of cleavage of neural cell adhesion molecule in neuronal death under o xidative stress conditions in cultured cortical neurons. Biol Pharm Bull 35:624–8.
  • Grashow R, Miller MW, McKinney A, et al. (2013). Lead exposure and fear-potentiated startle in the VA Normative Aging Study: a pilot study of a novel physiological approach to investigating neurotoxicant effects. Neurotoxicol Teratol 38:21–8.
  • Grigg-Damberger M, Ralls F. (2013). Treatment strategies for complex behavioral insomnia in children with neurodevelopmental disorders. Curr Opin Pulm Med 19:616–25.
  • Guo P, Wang YW, Weng BX, et al. (2014). Synthesis, anti-tumor activity, and structure-activity relationships of curcumol derivatives. J Asian Nat Prod Res 16:53–8.
  • Harrill JA, Freudenrich TM, Machacek DW, et al. (2010). Quantitative assessment of neurite outgrowth in human embryonic stem cell-derived hN2 cells using automated high-content image analysis. Neurotoxicology 31:277–90.
  • Hu Q, Fu H, Song H, et al. (2011). Low-level lead exposure attenuates the expression of three major isoforms of neural cell adhesion molecule. Neurotoxicology 32:255–60.
  • Huo Y, Qiu WY, Pan Q, et al. (2009). Reactive oxygen species (ROS) are essential mediators in epidermal growth factor (EGF)-stimulated corneal epithelial cell proliferation, adhesion, migration, and wound healing. Exp Eye Res 89:876–86.
  • Jenkins SM, Barone S. (2004). The neurotoxicant trimethyltin induces apoptosis via caspase activation, p38 protein kinase, and oxidative stress in PC12 cells. Toxicol Lett 147:63–72.
  • Kleene R, Mzoughi M, Joshi G, et al. (2010). NCAM-induced neurite outgrowth depends on binding of calmodulin to NCAM and on nuclear import of NCAM and fak fragments. J Neurosci 30:10784–98.
  • Lambert JD, Elias RJ. (2010). The antioxidant and pro-oxidant activities of green tea polyphenols: a role in cancer prevention. Arch Biochem Biophys 501:65–72.
  • Little EB, Crossin KL, Krushel LA, et al. (2001). A short segment within the cytoplasmic domain of the neural cell adhesion molecule (N-CAM) is essential for N-CAM-induced NF-kappa B activity in astrocytes. Proc Natl Acad Sci USA 98:2238–43.
  • Little J. (2000). Epidemiology of neurodevelopmental disorders in children. Prostaglandins Leukot Essent Fatty Acids 63:11–20.
  • Luo J, Qiu Z, Chen J, et al. (2013). Maternal and early life arsenite exposure impairs neurodevelopment and increases the expression of PSA-NCAM in hippocampus of rat offspring. Toxicology 311:99–106.
  • Miodovnik A. (2011). Environmental neurotoxicants and developing brain. Mt. Sinai J Med 78:58–77.
  • Musacco-Sebio R, Ferrarotti N, Saporito-Magriñá C, et al. (2014). Oxidative damage to rat brain in iron and copper overloads. Metallomics 6:1410–6.
  • Obermeier B, Daneman R, Ransohoff RM. (2013). Development, maintenance and disruption of the blood–brain barrier. Nat Med 19:1584–96.
  • Ogawa T, Kuwagata M, Hori Y, Shioda S. (2007). Valproate-induced developmental neurotoxicity is affected by maternal conditions including shipping stress and environmental change during early pregnancy. Toxicol Lett 174:18–24.
  • Prodromidou K, Papastefanaki F, Sklaviadis T, Matsas R. (2014). Functional cross-talk between the cellular prion protein and the neural cell adhesion molecule is critical for neuronal differentiation of neural stem/precursor cells. Stem Cells 32:1674–87.
  • Read DE, Gorman AM. (2009). Involvement of Akt in neurite outgrowth. Cell Mol Life Sci 66:2975–84.
  • Reiter TA, Pang B, Dedon P, Demple B. (2006). Resistance to nitric oxide-induced necrosis in heme oxygenase-1 overexpressing pulmonary epithelial cells associated with decreased lipid peroxidation. J Biol Chem 281:36603–12.
  • Schug TT, Erlebacher A, Leibowitz S, et al. (2012). Fetal programming and environmental exposures: implications for prenatal care and preterm birth. Ann N Y Acad Sci 1276:37–46.
  • Serrano J, Cipak A, Boada J, et al. (2010). Double-edged sword behaviour of gallic acid and its interaction with peroxidases in human microvascular endothelial cell culture (HMEC-1). Antioxidant and pro-oxidant effects. Acta Biochim Pol 57:193–8.
  • Sheppard A, Wu J, Rutishauser U, Lynch G. (1991). Proteolytic modification of neural cell adhesion molecule (NCAM) by the intracellular proteinase calpain. Biochim Biophys Acta 1076:156–60.
  • Slotkin TA, Card J, Seidler FJ. (2013). Adverse benzo[a]pyrene effects on neurodifferentiation are altered by other neurotoxicant coexposures: interactions with dexamethasone, chlorpyrifos, or nicotine in PC12 cells. Environ Health Perspect 121:825–31.
  • Slotkin TA, Seidler FJ. (2009). Oxidative and excitatory mechanisms of developmental neurotoxicity: transcriptional profiles for chlorpyrifos, diazinon, dieldrin, and divalent nickel in PC12 cells. Environ Health Perspect 117:587–96.
  • Slotkin TA, Seidler FJ. (2012). Developmental neurotoxicity of organophosphates targets cell cycle and apoptosis, revealed by transcriptional profiles in vivo and in vitro. Neurotoxicol Teratol 34:232–41.
  • Smirnova L, Hogberg HT, Leist M, Hartung T. (2014). Developmental neurotoxicity – challenges in the 21st century and in vitro opportunities. Altex 31:129–56.
  • Stigger F, Lovatel G, Marques M, et al. (2013). Inflammatory response and oxidative stress in developing rat brain and its consequences on motor behavior following maternal administration of LPS and perinatal anoxia. Int J Dev Neurosci 31:820–7.
  • Suzuki N, Numakawa T, Chou J, et al. (2014). Teneurin-4 promotes cellular protrusion formation and neurite outgrowth through focal adhesion kinase signaling. FASEB J 28:1386–97.
  • Visan A, Hayess K, Sittner D, et al. (2012). Neural differentiation of mouse embryonic stem cells as a tool to assess developmental neurotoxicity in vitro. Neurotoxicology 33:1135–46.
  • Winneke G. (2007). Appraisal of neurobehavioral methods in environmental health research: the developing brain as a target for neurotoxic chemicals. Int J Hyg Environ Health 210:601–9.
  • Yung HS, Lai KH, Chow KB, et al. (2010). Nerve growth factor-induced differentiation of PC12 cells is accompanied by elevated adenylyl cyclase activity. Neurosignals 18:32–42.
  • Zhang W, Wang Z, Chen T. (2011). Curcumol induces apoptosis via caspases-independent mitochondrial pathway in human lung adenocarcinoma ASTC-a-1 cells. Med Oncol 28:307–14.
  • Zhao X, Zou Y, Xu H, et al. (2012). Gastrodin protect primary cultured rat hippocampal neurons against amyloid-beta peptide-induced neurotoxicity via ERK1/2-Nrf2 pathway. Brain Res 1482:13–21.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.