179
Views
18
CrossRef citations to date
0
Altmetric
Research Article

PCB 118-induced endothelial cell apoptosis is partially mediated by excessive ROS production

, , , , , , & show all
Pages 394-399 | Received 15 Dec 2016, Accepted 11 Feb 2017, Published online: 11 Apr 2017

References

  • Arzuaga X, Reiterer G, Majkova Z, et al. (2007). PPARalpha ligands reduce PCB-induced endothelial activation: possible interactions in inflammation and atherosclerosis. Cardiovasc Toxicol 7:264–72.
  • Bergkvist C, Berglund M, Glynn A, et al. (2016). Dietary exposure to polychlorinated biphenyls and risk of myocardial infarction in men – a population-based prospective cohort study. Environ Int 88:9–14.
  • Bergkvist C, Berglund M, Glynn A, et al. (2015). Dietary exposure to polychlorinated biphenyls and risk of myocardial infarction – a population-based prospective cohort study. Int J Cardiol 183:242–8.
  • Choi JJ, Choi YJ, Chen L, et al. (2012). Lipopolysaccharide potentiates polychlorinated biphenyl-induced disruption of the blood-brain barrier via TLR4/IRF-3 signaling. Toxicology 302:212–20.
  • Das JK, Felty Q. (2014). PCB153-induced overexpression of ID3 contributes to the development of microvascular lesions. PLoS One 9:e104159.
  • Dimmeler S, Hermann C, Zeiher AM. (1998). Apoptosis of endothelial cells. Contribution to the pathophysiology of atherosclerosis? Eur Cytokine Netw 9:697–8.
  • Donat-Vargas C, Gea A, Sayon-Orea C, et al. (2015). Association between dietary intake of polychlorinated biphenyls and the incidence of hypertension in a Spanish cohort: the Seguimiento Universidad de Navarra project. Hypertension 65:714–21.
  • Eum SY, Andras I, Hennig B, Toborek M. (2009). NADPH oxidase and lipid raft-associated redox signaling are required for PCB153-induced upregulation of cell adhesion molecules in human brain endothelial cells. Toxicol Appl Pharmacol 240:299–305.
  • Eum SY, Andras IE, Couraud PO, et al. (2008). Pcbs and tight junction expression. Environ Toxicol Pharmacol 25:234–40.
  • Eum SY, Jaraki D, Andras IE, Toborek M. (2015). Lipid rafts regulate PCB153-induced disruption of occludin and brain endothelial barrier function through protein phosphatase 2A and matrix metalloproteinase-2. Toxicol Appl Pharmacol 287:258–66.
  • Gimbrone MA, Jr., Garcia-Cardena G. (2016). Endothelial cell dysfunction and the pathobiology of atherosclerosis. Circ Res 118:620–36.
  • Ha MH, Lee DH, Jacobs DR. (2007). Association between serum concentrations of persistent organic pollutants and self-reported cardiovascular disease prevalence: results from the National Health and Nutrition Examination Survey, 1999–2002. Environ Health Perspect 115:1204–9.
  • Hardwick JM, Soane L. (2013). Multiple functions of BCL-2 family proteins. Cold Spring Harb Perspect Biol 5:a008722.
  • Helyar SG, Patel B, Headington K, et al. (2009). PCB-induced endothelial cell dysfunction: role of poly(ADP-ribose) polymerase. Biochem Pharmacol 78:959–65.
  • Hwang SG, Lee HC, Lee DW, et al. (2001). Induction of apoptotic cell death by a p53-independent pathway in neuronal SK-N-MC cells after treatment with 2,2′,5,5′-tetrachlorobiphenyl. Toxicology 165:179–88.
  • Inglefield JR, Mundy WR, Shafer TJ. (2001). Inositol 1,4,5-triphosphate receptor-sensitive Ca(2+) release, store-operated Ca(2+) entry, and cAMP responsive element binding protein phosphorylation in developing cortical cells following exposure to polychlorinated biphenyls. J Pharmacol Exp Ther 297:762–73.
  • Lee YW, Park HJ, Son KW, et al. (2003). 2,2′,4,6,6′-pentachlorobiphenyl (PCB 104) induces apoptosis of human microvascular endothelial cells through the caspase-dependent activation of CREB. Toxicol Appl Pharmacol 189:1–10.
  • Li P, Nijhawan D, Budihardjo I, et al. (1997). Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade. Cell 91:479–89.
  • Lind PM, Van Bavel B, Salihovic S, Lind L. (2012). Circulating levels of persistent organic pollutants (POPs) and carotid atherosclerosis in the elderly. Environ Health Perspect 120:38–43.
  • Mallat Z, Tedgui A. (2000). Apoptosis in the vasculature: mechanisms and functional importance. Br J Pharmacol 130:947–62.
  • Murphy MO, Petriello MC, Han SG, et al. (2016). Exercise protects against PCB-induced inflammation and associated cardiovascular risk factors. Environ Sci Pollut Res Int 23:2201–11.
  • Rotllan N, Wanschel AC, Fernandez-Hernando A, et al. (2015). Genetic evidence supports a major role for Akt1 in VSMCs during atherogenesis. Circ Res 116:1744–52.
  • Seelbach M, Chen L, Powell A, et al. (2010). Polychlorinated biphenyls disrupt blood-brain barrier integrity and promote brain metastasis formation. Environ Health Perspect 118:479–84.
  • Shin KJ, Bae SS, Hwang YA, et al. (2000). 2,2′,4,6,6′-Pentachlorobiphenyl induces apoptosis in human monocytic cells. Toxicol Appl Pharmacol 169:1–7.
  • Sinha K, Das J, Pal PB, Sil PC. (2013). Oxidative stress: the mitochondria-dependent and mitochondria-independent pathways of apoptosis. Arch Toxicol 87:1157–80.
  • Sipos E, Chen L, Andras IE, et al. (2012). Proinflammatory adhesion molecules facilitate polychlorinated biphenyl-mediated enhancement of brain metastasis formation. Toxicol Sci 126:362–71.
  • Slim R, Toborek M, Robertson LW, et al. (2000). Cellular glutathione status modulates polychlorinated biphenyl-induced stress response and apoptosis in vascular endothelial cells. Toxicol Appl Pharmacol 166:36–42.
  • Toborek M, Barger SW, Mattson MP, et al. (1995). Exposure to polychlorinated biphenyls causes endothelial cell dysfunction. J Biochem Toxicol 10:219–26.
  • Volkmann N, Marassi FM, Newmeyer DD, Hanein D. (2014). The rheostat in the membrane: BCL-2 family proteins and apoptosis. Cell Death Differ 21:206–15.
  • Wei MC, Zong WX, Cheng EH, et al. (2001). Proapoptotic BAX and BAK: a requisite gateway to mitochondrial dysfunction and death. Science 292:727–30.
  • WHO. (2014). Global status report on noncommunicable diseases 2014. Switzerland; World Health Organization.
  • Yoo BS, Jung KH, Hana SB, Kim HM. (1997). Apoptosis-mediated immunotoxicity of polychlorinated biphenyls (PCBs) in murine splenocytes. Toxicol Lett 91:83–9.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.