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Research Article

Rotenone induces nephrotoxicity in rats: oxidative damage and apoptosis

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Pages 528-536 | Received 16 Jan 2017, Accepted 07 May 2017, Published online: 20 Jun 2017

References

  • Arnhold M, Dening Y, Chopin M, Arévalo E, Schwarz M, Reichmann H, Gille G, Funk RHW, Pan-Montojo F. 2016. Changes in the sympathetic innervation of the gut in rotenone treated mice as possible early biomarker for Parkinson’s disease. Clin Auton Res. 26:211–222.
  • Bonet-Ponce L, Saez-Atienzar S, Casa CD, Sancho-Pelluz J, Barcia JM, Martinez-Gil N, Nava E, Jordan J, Romero FJ, Galindo MF. 2016. Rotenone induces the formation of 4-hydroxynonenal aggresomes. Role of ROS-mediated tubulin hyperacetylation and autophagic flux disruption. Mol Neurobiol. 53:6194–6208.
  • Bongard RD, Townsley MI, Merker MP. 2014. The effects of mitochondrial complex I blockade on ATP and permeability in rat pulmonary microvascular endothelial cells in culture (PMVEC) are overcome by coenzyme Q1 (CoQ1). Free Radic Biol Med. 79:69–77.
  • Brown PJ, Johnson H, Zale, AV. 2011. Effect of rainbow trout size on response to rotenone and antimycin. N Am J Fish Manage. 31:1146–1152.
  • Caboni P, Sherer TB, Zhang N, Taylor G, Na HM, Greenamyre JT, Casida JE. 2004. Rotenone, deguelin, their metabolites, and the rat model of Parkinson’s disease. Chem Res Toxicol. 17:1540–1548.
  • Darr CR, Varner DD, Teague S, Cortopassi GA, Datta S, Meyers SA. 2016. Lactate and pyruvate are major sources of energy for stallion sperm with dose effects on mitochondrial function, motility, and ROS production. Biol Reprod. 95:34.
  • Erbaş O, Yılmaz M, Taşkıran, D. 2016. Levetiracetam attenuates rotenone-induced toxicity: a rat model of Parkinson’s disease. Environ Toxicol Pharmacol. 42:226–230.
  • Gielisch I, Meierhofer D. 2015. Metabolome and proteome profiling of complex I deficiency induced by rotenone. J Proteome Res. 14:224–235.
  • Hsiao YP, Huang HL, Lai WW, Chung JG, Yang JH. 2009. Antiproliferative effects of lactic acid via the induction of apoptosis and cell cycle arrest in a human keratinocyte cell line (HaCaT). J Dermatol Sci. 54:175–184.
  • Jing S. 2015. Environment-contact administration of rotenone: a new rodent model of Parkinson’s disease. Behav Brain Res. 294:149–161.
  • Keinan N, Pahima H, Ben-Hail D, Shoshan-Barmatz V. 2013. The role of calcium in VDAC1 oligomerization and mitochondria-mediated apoptosis. Biochim Biophys Acta. 1833:1745–1754.
  • Kuter K, Olech L, Dencher NA, 2015. Prolonged astrocytes dysfunction and dopaminergic neurons degeneration cause small changes in mitochondrial complex I and IV activity and supercomplexes assembly in substantia nigra. Glia. 63:141–142.
  • Lazo CR, Guillot TS, Miller GW. 2014. Rotenone. Eur Arch Psychiatry Clin Neurosci. 96:74–75.
  • Li L, Dong X, Shu B, Wang Z, Hu Q, Zhong G. 2014. Iron-sulfur protein in mitochondrial complexes of Spodoptera litura as potential site for ROS generation. J Insect Physiol. 71:21–29.
  • Martel C, Wang Z, Brenner C. 2014. VDAC phosphorylation, a lipid sensor influencing the cell fate. Mitochondrion. 19:69–77.
  • Martinez TN, Greenamyre JT. 2012. Toxin models of mitochondrial dysfunction in Parkinson’s disease. Antioxid Redox Signal. 16:920–934.
  • Meng QH, Liu HB, Wang JB. 2016. Polydatin ameliorates renal ischemia/reperfusion injury by decreasing apoptosis and oxidative stress through activating sonic hedgehog signaling pathway. Food Chem Toxicol. 96:215–225.
  • Naidu V, Mahesh BU, Giddam AK, Babu KR, Ding J, Babu KS, Ramesh B, Pragada RR, Gopalakrishnakone P. 2013. Apoptogenic activity of ethyl acetate extract of leaves of Memecylon edule on human gastric carcinoma cells via mitochondrial dependent pathway. Asian Pac J Trop Dis. 6:337–345.
  • Nordin N, Fadaeinasab M, Mohan S, Mohd Hashim N, Othman R, Karimian H, Iman V, Ramli N, Mohd Ali H, Abdul Majid N. 2016. Pulchrin A, a new natural coumarin derivative of Enicosanthellum pulchrum, induces apoptosis in ovarian cancer cells via intrinsic pathway. PLoS One. 11:e0154023.
  • Olson H, Betton G, Robinson D, Thomas K, Monro A, Kolaja G, Lilly P, Sanders J, Sipes G, Bracken W. 2000. Concordance of the toxicity of pharmaceuticals in humans and in animals. Regul Toxicol Pharmacol. 32:56–67.
  • Phalitakul S, Okada M, Hara Y, Yamawaki H. 2013. Vaspin prevents methylglyoxal-induced apoptosis in human vascular endothelial cells by inhibiting reactive oxygen species generation. Acta Physiol (Oxf). 209:212–219.
  • Sala G, Marinig D, Riva C, Arosio A, Stefanoni G, Brighina L, Formenti M, Alberghina L, Colangelo AM, Ferrarese C. 2016. Rotenone down-regulates HSPA8/hsc70 chaperone protein in vitro: a new possible toxic mechanism contributing to Parkinson's disease. Neurotoxicology. 54:161–169.
  • Shehata AM. 2012. Evaluation of rotenone to produce an experimental model for Parkinson’s disease. A neuroprotective effect of coenzyme Q-10. Parkinsonism Relat Disord. 18(Suppl. 2):192.
  • Shoshan-Barmatz V, Keinan N, Abu-Hamad S, Tyomkin D, Aram L. 2010. Apoptosis is regulated by the VDAC1 N-terminal region and by VDAC oligomerization: release of cytochrome c, AIF and Smac/Diablo. Biochim Biophys Acta. 1797:1281–1291.
  • Stelmashook EV, Lozier ER, Goryacheva ES, Mergenthaler P, Novikova SV, Zorov DB, Isaev NK. 2010. Glutamine-mediated protection from neuronal cell death depends on mitochondrial activity. Neurosci Lett. 482:151–155.
  • Sun Y, Zhang Y, Zhao D, Ding G, Huang S, Zhang A, Jia Z. 2014. Rotenone remarkably attenuates oxidative stress, inflammation, and fibrosis in chronic obstructive uropathy. Mediators Inflamm. 2014:202–204.
  • Tanner CM, Kamel F, Ross GW, Hoppin JA, Goldman SM, Korell M, Marras C, Bhudhikanok GS, Kasten M, Chade AR, et al. 2011. Rotenone, paraquat, and Parkinson’s disease. Environ Health Perspect. 119:866–872.
  • Verma DK, Joshi N, Raju KS, Wahajuddin M, Singh RK, Singh S. 2015. Metabolic enhancer piracetam attenuates rotenone induced oxidative stress: a study in different rat brain regions. Acta Neurobiol Exp. 75:399–411.
  • Wang HF, Lin PP, Chen CH, Yeh YL, Huang CC, Huang CY, Tsai CC. 2015. Effects of lactic acid bacteria on cardiac apoptosis are mediated by activation of the phosphatidylinositol-3 kinase/AKT survival-signalling pathway in rats fed a high-fat diet. Int J Mol Med. 35:460–470.
  • Wei D, Xu C, Wang B, Zhang M. 2015. Rotenone attenuates renal injury in aldosterone-infused rats by inhibiting oxidative stress, mitochondrial dysfunction, and inflammasome activation. Med Sci Monit. 21:3136–3143.
  • Wilkinson D, Ramsdale, M. 2011. Proteases and caspase-like activity in the yeast Saccharomyces cerevisiae. Biochem Soc Trans. 39:1502–1508.
  • Wu J, Li X, Zhu G, Zhang Y, He M, Zhang J. 2016. The role of Resveratrol-induced mitophagy/autophagy in peritoneal mesothelial cells inflammatory injury via NLRP3 inflammasome activation triggered by mitochondrial ROS. Exp Cell Res. 341:42–53.
  • Xiong N, Long X, Xiong J, Jia M, Chen C, Huang J, Ghoorah D, Kong X, Lin Z, Wang T. 2012. Mitochondrial complex I inhibitor rotenone-induced toxicity and its potential mechanisms in Parkinson’s disease models. Crit Rev Toxicol. 42:613–632.
  • Xiong H, Wei B, Wei R, Ning-hai Y, Mei-ying Q, Juan J, Yong J, Jian H, Rui-xia D. 2013. Calculation of median lethal dose (LD) for Yersinia pestis by SPSS package. Chin J Zoonoses. 29:1127–1130.
  • Yu J, Xu H, Shen X, Jiang H. 2015. Ghrelin protects MES23.5 cells against rotenone via inhibiting mitochondrial dysfunction and apoptosis. Neuropeptides. 56:69–74.
  • Zhou Y, Peng Y, Mao QQ, Li X, Chen MW, Su J, Tian L, Nai-Quan M. 2013. Casticin induces caspase-mediated apoptosis via activation of mitochondrial pathway and upregulation of DR5 in human lung cancer cells. Asian Pac J Trop Dis. 6:372–378.
  • Zhou Q, Liu C, Liu W, Zhang H, Zhang R, Liu J, Zhang J, Xu C, Liu L, Huang S, Chen L. 2015. Rotenone induction of hydrogen peroxide inhibits mTOR-mediated S6K and 4E-BP1/eIF4E pathways, leading to neuronal apoptosis. Toxicol Sci. 143:81–96.
  • Zhu FY, Radad K, Krewenka C, Kranner B, Duvigneau JC, Rausch WD. 2011. Effects of epigallocatechin gallate on rotenone-induced injury in PC12 cells. Chin J Pharmacol Toxicol. 25:52–56.
  • Zorov DB, Juhaszova M, Yaniv Y, Bradley Nuss H, Wang S, Sollott SJ. 2009. Regulation and pharmacology of the mitochondrial permeability transition pore. Cardiovasculs Res. 83:213–225.

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