The interplay between TGF-β/SMAD and BMP/SMAD signaling pathways in the epithelial mesenchymal transition of A549 cells induced by silica

References

• Akhurst RJ, Derynck R. 2001. TGF-beta signaling in cancer – a double-edged sword. Trends Cell Biol. 11:S44–S51.
   PubMed Web of Science ®Google Scholar
• Bramlage CP, Müller GA, Tampe B, Bevanda J, Maatouk I, Koziolek M, Lange K, Ahrens K, Schmid H, Cohen CD, et al. 2011. The role of bone morphogenetic protein-5 (BMP-5) in human nephrosclerosis. J Nephrol. 24:647–655.
   PubMed Web of Science ®Google Scholar
• Buijs JT, Henriquez NV, van Overveld PG, van der Horst G, Que I, Schwaninger R, Rentsch C, Ten Dijke P, Cleton-Jansen AM, Driouch K, et al. 2007. Bone morphogenetic protein 7 in the development and treatment of bone metastases from breast cancer. Cancer Res. 67:8742–8751.
   PubMed Web of Science ®Google Scholar
• Chea SW, Lee KB. 2009. TGF-beta mediated epithelial-mesenchymal transition in autosomal dominant polycystic kidney disease. Yonsei Med J. 50:105–111.
   PubMed Web of Science ®Google Scholar
• Chen D, Zhao M, Mundy GR. 2004. Bone morphogenetic proteins. Growth Factors. 22:233–241.
   PubMed Web of Science ®Google Scholar
• Derynck R, Feng XH. 1997. TGF-beta receptor signaling. Biochim Biophys Acta. 1333:F105–F150.
   PubMed Web of Science ®Google Scholar
• Hjelmeland MD, Hjelmeland AB, Sathornsumetee S, Reese ED, Herbstreith MH, Laping NJ, Friedman HS, Bigner DD, Wang XF, Rich JN. 2004. SB-431542, a small molecule transforming growth factor-beta-receptor antagonist, inhibits human glioma cell line proliferation and motility. Mol Cancer Ther. 3:737–745.
   PubMed Web of Science ®Google Scholar
• Kim KK, Kugler MC, Wolters PJ, Robillard L, Galvez MG, Brumwell AN, Sheppard D, Chapman HA. 2006. Alveolar epithelial cell mesenchymal transition develops in vivo during pulmonary fibrosis and is regulated by the extracellular matrix. Proc Natl Acad Sci USA. 103:13180–13185.
   PubMed Web of Science ®Google Scholar
• Kim KK, Wei Y, Szekeres C, Kugler MC, Wolters PJ, Hill ML, Frank JA, Brumwell AN, Wheeler SE, Kreidberg JA, et al. 2009. Epithelial cell alpha3beta1 integrin links beta-catenin and Smad signaling to promote myofibroblast formation and pulmonary fibrosis. J Clin Invest. 119:213–224.
   PubMed Web of Science ®Google Scholar
• Kolosova I, Nethery D, Kern JA. 2011. Role of Smad2/3 and p38 MAP kinase in TGF-beta1-induced epithelial-mesenchymal transition of pulmonary epithelial cells. J Cell Physiol. 226:1248–1254.
   PubMed Web of Science ®Google Scholar
• Leung CC, Yu IT, Chen W. 2012. Silicosis. Lancet. 379:2008–2018.
   PubMed Web of Science ®Google Scholar
• Liu Q, Mao H, Nie J, Chen W, Yang Q, Dong X, Yu X. 2008. Transforming growth factor {beta}1 induces epithelial-mesenchymal transition by activating the JNK-Smad3 pathway in rat peritoneal mesothelial cells. Perit Dial Int. 28(Suppl 3):S88–S95.
   PubMed Web of Science ®Google Scholar
• Liu Q, Zhang Y, Mao H, Chen W, Luo N, Zhou Q, Chen W, Yu X. 2012. A crosstalk between the Smad and JNK signaling in the TGF-beta-induced epithelial-mesenchymal transition in rat peritoneal mesothelial cells. PLoS One. 7:e32009.
   PubMed Web of Science ®Google Scholar
• Liu Y. 2004. Epithelial to mesenchymal transition in renal fibrogenesis: pathologic significance, molecular mechanism, and therapeutic intervention. J Am Soc Nephrol. 15:1–12.
   PubMed Web of Science ®Google Scholar
• Mikami Y, Yamauchi Y, Horie M, Kase M, Jo T, Takizawa H, Kohyama T, Nagase T. 2012. Tumor necrosis factor superfamily member LIGHT induces epithelial-mesenchymal transition in A549 human alveolar epithelial cells. Biochem Biophys Res Commun. 428:451–457.
   PubMed Web of Science ®Google Scholar
• Mossman BT, Churg A. 1998. Mechanisms in the pathogenesis of asbestosis and silicosis. Am J Respir Crit Care Med. 157:1666–1680.
   PubMed Web of Science ®Google Scholar
• Myllarniemi M, Lindholm P, Ryynänen MJ, Kliment CR, Salmenkivi K, Keski-Oja J, Kinnula VL, Oury TD, Koli K. 2008. Gremlin-mediated decrease in bone morphogenetic protein signaling promotes pulmonary fibrosis. Am J Respir Crit Care Med. 177:321–329.
   PubMed Web of Science ®Google Scholar
• Nie J, Dou X, Hao W, Wang X, Peng W, Jia Z, Chen W, Li X, Luo N, Lan HY, et al. 2007. Smad7 gene transfer inhibits peritoneal fibrosis. Kidney Int. 72:1336–1344.
   PubMed Web of Science ®Google Scholar
• O’Kane D, Jackson MV, Kissenpfennig A, Spence S, Damkat-Thomas L, Tolland JP, Smyth AE, Denton CP, Stuart Elborn J, McAuley DF, et al. 2014. SMAD inhibition attenuates epithelial to mesenchymal transition by primary keratinocytes in vitro. Exp Dermatol. 23:497–503.
   PubMed Web of Science ®Google Scholar
• Palma-Nicolás JP, López-Colomé AM. 2013. Thrombin induces slug-mediated E-cadherin transcriptional repression and the parallel up-regulation of N-cadherin by a transcription-independent mechanism in RPE cells. J Cell Physiol. 228:581–589.
   PubMed Web of Science ®Google Scholar
• Tamiya S, Liu L, Kaplan HJ. 2010. Epithelial-mesenchymal transition and proliferation of retinal pigment epithelial cells initiated upon loss of cell-cell contact. Invest Ophthalmol Vis Sci. 51:2755–2763.
   PubMed Web of Science ®Google Scholar
• Tanjore H, Xu XC, Polosukhin VV, Degryse AL, Li B, Han W, Sherrill TP, Plieth D, Neilson EG, Blackwell TS, et al. 2009. Contribution of epithelial-derived fibroblasts to bleomycin-induced lung fibrosis. Am J Respir Crit Care Med. 180:657–665.
   PubMed Web of Science ®Google Scholar
• Wang XM, Zhang Y, Kim HP, Zhou Z, Feghali-Bostwick CA, Liu F, Ifedigbo E, Xu X, Oury TD, Kaminski N, et al. 2006. Caveolin-1: a critical regulator of lung fibrosis in idiopathic pulmonary fibrosis. J Exp Med. 203:2895–2906.
   PubMed Web of Science ®Google Scholar
• Yang G, Zhu Z, Wang Y, Gao A, Niu P, Chen L, Tian L. 2016. Bone morphogenetic protein 7 attenuates epithelial-mesenchymal transition induced by silica. Hum Exp Toxicol. 35:69–77.
   PubMed Web of Science ®Google Scholar
• Yang G, Zhu Z, Wang Y, Gao A, Niu P, Tian L. 2013. Bone morphogenetic protein-7 inhibits silica-induced pulmonary fibrosis in rats. Toxicol Lett. 220:103–108.
   PubMed Web of Science ®Google Scholar
• Yew KH, Hembree M, Prasadan K, Preuett B, McFall C, Benjes C, Crowley A, Sharp S, Tulachan S, Mehta S, et al. 2005. Cross-talk between bone morphogenetic protein and transforming growth factor-beta signaling is essential for exendin-4-induced insulin-positive differentiation of AR42J cells. J Biol Chem. 280:32209–32217.
   PubMed Web of Science ®Google Scholar
• Zhong Q, Zhou B, Ann DK, Minoo P, Liu Y, Banfalvi A, Krishnaveni MS, Dubourd M, Demaio L, Willis BC, et al. 2011. Role of endoplasmic reticulum stress in epithelial-mesenchymal transition of alveolar epithelial cells: effects of misfolded surfactant protein. Am J Respir Cell Mol Biol. 45:498–509.
   PubMed Web of Science ®Google Scholar