Patho-physiological and toxicological aspects of monosodium glutamate

References

• Ali MM, Bawari M, Misra UK, Babu GN. 2000. Locomotor and learning deficits in adult rats exposed to monosodium-l-glutamate during early life. Neurosci Lett. 284:57–60.
   PubMed Web of Science ®Google Scholar
• American Medical Association Council on Scientific Affairs. 1992. Report regarding the inclusion of added Lrglutamic acid content on food labels. Report D (A-92). p. 1–6.
   Google Scholar
• [AAPCD] American Academy of Pediatrics’ Committee on Drugs 1994. The transfer of drugs and other chemicals into human milk. Pediatr. 93:137–150.
   PubMed Web of Science ®Google Scholar
• Ball P, Woodward D, Beard T, Shoobridge A, Ferrier M. 2002. Calcium di-glutamate improves taste characteristics of lower salt soup. Eur J Clin Nutr. 56:519–523.
   PubMed Web of Science ®Google Scholar
• Battaglia FC. 2000. Glutamine and glutamate exchange between the fetal liver and the placenta. J Nutr. 130:974S–977S.
   PubMed Web of Science ®Google Scholar
• Bazzano G, D'Elia JA, Olson RE. 1970. Monosodium glutamate: feeding of large amounts in man and gerbils. Science. 169:1208–1209.
   PubMed Web of Science ®Google Scholar
• Bellisle F, Monneuse MO, Chabert M, Larue-Achagiotis C, Lanteaume MT, Louis-Sylvestre J. 1991. Monosodium glutamate as a palatability enhancer in the European diet. Physiol Behaviour. 49:869–873.
   PubMed Web of Science ®Google Scholar
• Beyreuther K, Biesalski HK, Fernstrom JD, Grimm P, Hammes WP, Heinemann U, Kempski O, Stehle P, Steinhart H, Walker R. 2007. Consensus meeting: monosodium glutamate - an update. Eur J Clin Nutr. 61:304–313.
   PubMed Web of Science ®Google Scholar
• Bojanic V, Bojanic Z, Najman S, Savic T, Jakovljevic V, Najman S, Jancic S. 2009. Diltiazem prevention of toxic effects of monosodium glutamate on ovaries in rats. General Physiol Biophys. 28:149–154.
   PubMed Web of Science ®Google Scholar
• Denno DW. 2015. The myth of the double-edged sword: an empirical study of neuroscience evidence in criminal cases. Boston Coll Law Rev. 56(2):493–551.
   Google Scholar
• Diniz YS, Fernandes AAH, Campos KE, Mani F, Ribas BO, Novelli ELB. 2004. Toxicity of hyper caloric diet and monosodium glutamate: Oxidative stress and metabolic shifting in hepatic tissue. Food Chem Toxicol. 42:319–325.
   Web of Science ®Google Scholar
• Farombi EO, Onyema OO. 2006. Monosodium glutamate-induced oxidative damage and genotoxicity in the rat: modulatory role of vitamin C, vitamin E and quercetin. Hum Exp Toxicol. 25:251–259.
   PubMed Web of Science ®Google Scholar
• FDA Backgrounder, supra note 7, at 2. See also International Glutamate Information Service, Approvals. [accessed 1995 August 31]. http://www.glutamate.org/media/approvals.html.
   Google Scholar
• FDA. 1997. Substances generally recognized as safe; Proposed rule (21 CFR Parts 170, 184, 186, and 570) [Docket No. 97N-0103]. Fed regist (US). 62(74):18937–18964. Available at: http://www.gpo.gov/fdsys/pkg/FR-1997-04-17/pdf/97-9706.pdf.
   Google Scholar
• Freeman M. 2006. Reconsidering the effects of monosodium glutamate: a literature review. J Am Acad Nurse Pract. 18:482–486.
   PubMed Web of Science ®Google Scholar
• Geha RS, Beiser A, Ren C, Patterson R, Greenberger PA, Grammer LC, Ditto AM, Harris KE, Shaughnessy MA, Yarnold PR, et al. 2000. Review of alleged reaction to monosodium glutamate and outcome of a multicenter double-blind placebo-controlled study. Journal Nutr. 130:1058S–105862S.
   PubMed Web of Science ®Google Scholar
• Gore ME, Salmon PR. 1980. Chinese restaurant syndrome: fact or fiction? [letter]. Lancet. 1:251–252.
   PubMed Web of Science ®Google Scholar
• Gupta A, Epstein JB, Sroussi H. 2006. Hyposalivation in elderly patients. J Can Dent Assoc. 72:841–846.
   PubMedGoogle Scholar
• Hallagan JB, Hall RL. 1995. FEMA GRAS - A GRAS assessment program for flavor ingredients. Regul Toxicol Pharmacol. 21:422.
   PubMed Web of Science ®Google Scholar
• Hashem HE, El-Din Safwat MD, Algaidi S. 2012. The effect of monosodium glutamate on the cerebellar cortex of male albino rats and the protective role of vitamin C (Histological and Immunohistochemical Study). J Mol Histol. 43:179–186.
   PubMed Web of Science ®Google Scholar
• Hayakawa Y, Kawai M, Sakai R. 2007. Umami sensitivity of the elderly females-comparison with middle-aged females. Japanese J Taste Smell Res. 14:443–446.
   Google Scholar
• Hayakawa Y, Kawai M, Torii K, Uneyama H. 2008. The effect of umami taste on saliva secretion. Japanese J Taste Smell Res. 15:367–370.
   Google Scholar
• Hsu SJ, Huang PC. 1985. Effects of monosodium glutamate loading upon plasma free amino acids and ammonia levels in Chinese male adults. Taiwan Yi Xue Hui Za Zhi Assoc. 84:1017–1024.
   PubMedGoogle Scholar
• Horio T, Kawamura Y. 1989. Salivary secretion induced by umami taste. Shika Kiso Igakkai Zasshi. 31:107–111.
   Google Scholar
• Husarova V, Ostatnikova D. 2013. Monosodium glutamate toxic effects and their implications for human intake: a review. JMED Res. 1. 2013(2013): Article ID 608765, DOI: 10.5171/2013.608765.
   Google Scholar
• Husarova V, Ostatnikov D. 2007. Monosodium glutamate toxic effects and their implications for human intake: a review. Eur J Clin Nutr. 34:758–765.
   Google Scholar
• Ikeda K. 2002. New seasonings. Chem Senses. 27:847–849.
   Google Scholar
• Kazmi Z, Fatima I, Perveen S, Malik SS. 2017. Monosodium glutamate: review on clinical reports. Int J of Food Prop. 20(Supl. 2):1807–1815
   Google Scholar
• Kenney RA. 1980. Chinese restaurant syndrome [letter]. Lancet. 1:311–312.
   PubMed Web of Science ®Google Scholar
• Kenney RA, Tidball CS. 1972. Human susceptibility to oral monosodium L-glutamate. Am J Clin Nutr. 25:140–146.
   PubMed Web of Science ®Google Scholar
• Koya D, Hayashi K, Kitada M, Kashiwagi A, Kikkawa R, Haneda M. 2003. Effects of antioxidants in diabetes-induced oxidative stress in the glomeruli of diabetic rats. J Am Soc Nephrol. 14:S250–S2S3.
   PubMed Web of Science ®Google Scholar
• Lindemann B, Ogiwara Y, Ninomiya Y. 2002. The Discovery of Umami. Chem Senses. 27:843–844.
   PubMed Web of Science ®Google Scholar
• Lorden JF, Caudle A. 1986. Behavioral and endocrinological effects of single injections of monosodium glutamate in the mouse. Neurobehav Toxicol Teratol. 8:509–519.
   PubMedGoogle Scholar
• Marrs TC, Salmona M, Garattini S, Burston D, Matthews DM. 1978. The absorption by human volunteers of glutamic acid from monosodium glutamate and from a partial enzymic hydrolysate of casein. Toxicol. 11:101–107.
   PubMed Web of Science ®Google Scholar
• Meldrum BS. 2000. Glutamate as a neurotransmitter in the brain: review of physiology and pathology. J Nutr. 130:1007S–1015S.
   PubMed Web of Science ®Google Scholar
• Metcalfe CE. 1998. The stakeholder corporation. Business ethics. 7:30–36.
   Google Scholar
• Morselli PL, Garattini S. 1970. Monosodium glutamate and the Chinese restaurant syndrome. Nature. 227:611–612.
   PubMed Web of Science ®Google Scholar
• Nicholas JM. 2001. Glutamate transporters in neurologic disease. Arch Neurol. 58:365–370.
   PubMedGoogle Scholar
• Ninomiya K. 1998. Natural occurrence. Food Rev Inter.14:177–211.
   Web of Science ®Google Scholar
• Onyema OO, Farombi EO, Emerole GO, Ukoha AL, Onyeze GO. 2006. Effect of vitamin E on monosodium glutamate induced hepatoxicity and oxidative stress in rats. Indian J Biochem Biophy. 43:20–24.
   PubMed Web of Science ®Google Scholar
• Pelaez B. 2001. Lectin histochemistry and ultra-structure of microglial response to monosodium glutamate-mediated neurotoxicity in the arcuate nucleus. Arch Neurol. 14:165–174.
   Google Scholar
• Pelaez B, Blazquez JL, Pastor FE, Sanchez A, Amat P. 1999. Lectin histochemistry and ultrastructure of microglial response to monosodium glutamate-mediated neurotoxicity in the arcuate nucleus. Histol histopathol. 14:165–174.
   PubMed Web of Science ®Google Scholar
• Proctor GB, Carpenter GH. 2007. Regulation of salivary gland function by autonomic nerves. Auton Neurosci. 133:3–18.
   PubMed Web of Science ®Google Scholar
• Rivera-Cervantes MC, Torres JS, Feria-Velasco A, Armendariz-Borunda J, Beas ZC. 2004. NMDA and AMPA receptor expression and cortical neuronal death are associated with p38 in glutamate-induced excitotoxicity in vivo. J Neurosci Res. 76:678–685.
   PubMed Web of Science ®Google Scholar
• Rosenblum I, Bradley JD, Coulston F. 1971. Single and double blind studies with oral monosodium glutamate in man. Toxicol Appl Pharmacol. 18:367–373.
   PubMed Web of Science ®Google Scholar
• Sano C. 2009. History of glutamate production. Am J Clin Nutr. 90:728S–732S.
   PubMed Web of Science ®Google Scholar
• Schaumburg HH, Byck R, Gerstl R, Mashman JH. 1969. Monosodium L-glutamate: its pharmacology and role in the Chinese restaurant syndrome. Science. 163:826–828.
   PubMed Web of Science ®Google Scholar
• Schiffman SS. 2000. Intensification of sensory properties of foods for the elderly. J Nutr. 130:927S–930S.
   PubMed Web of Science ®Google Scholar
• Schiffman SS, Miletic ID. 1999. Effect of taste and smell on secretion rate of salivary IgA in elderly and young persons. J Nutr Health Aging. 3:158–164.
   PubMedGoogle Scholar
• [SCOGS] Select Committee on GRAS Substances. 1980. Evaluation of the health aspects of certain glutamates as a food ingredient (SCOGS-37a.-Suppl.). Paper presented to U.S. Food and Drug Administration. Washington (DC): Department of Health, Education, and welfare.
   Google Scholar
• Seiva FRF, Chuffa LGA, Braga CP, Amorim JPA, Fernandes AAH. 2012. Quercetin ameliorates glucose and lipid metabolism and improves antioxidant status in postnatally monosodium glutamate induced metabolic alterations. Food Chem Toxicol. 50:3556–3561.
   PubMed Web of Science ®Google Scholar
• Selvakumar E, Prahalathan C, Sudharsan PT, Varalakshmi P. 2006. Chemoprotective effect of lipoic acid against cyclophosphamide-induced changes in the rat sperm. Toxicology. 217:71–78.
   PubMed Web of Science ®Google Scholar
• Shi Z, Luscombe-Marsh ND, Wittert GA, Yuan B, Dai Y, Pan X, Taylor AW. 2010. Monosodium glutamate is not associated with obesity or a greater prevalence of weight gain over 5 years: findings from the Jiangsu nutrition study of Chinese adults. Br J Nutr. 104:457–463.
   PubMed Web of Science ®Google Scholar
• Shi HB, Masuda M, Umezaki T, Kuratomi Y, Kumamoto Y, Yamamoto T, Komiyama S. 2004. Irradiation impairment of umami taste in patients with head and neck cancer. Auris Nasus Larynx. 31:401–406.
   PubMed Web of Science ®Google Scholar
• Singh P, Mann KA, Mangat HK, Kaur G. 2003. Prolonged glutamate excitotoxicity effects on mitochondrial antioxidants and antioxidant enzymes. Mol Cell Biochem. 243:139–145.
   PubMed Web of Science ®Google Scholar
• Stegink LD, Filer LJ, Jr., Baker GL. 1981. Effect of aspartame and sucrose loading in glutamate-susceptible subjects. Am J Clin Nutr. 34:1899–1905.
   PubMed Web of Science ®Google Scholar
• Tung TC, Tung KS. 1980. Serum free amino acid levels after oral glutamate intake in infants and human adults. Nutr Rep Inter. 22:431–443.
   Google Scholar
• Walker R, Lupien JR. 2000. The safety evaluation of monosodium glutamate. J Nutr. 130:1049S–1052S.
   PubMed Web of Science ®Google Scholar
• Yamaguchi S, Ninomiya K. 1998. What is umami? Food Rev Inter. 14:123–138.
   Web of Science ®Google Scholar
• Yeomans MR, Gould NJ, Mobini S, Prescott J. 2008. Acquired flavor acceptance and intake facilitated by monosodium glutamate in humans. Physiol Behav. 93:958–966.
   PubMed Web of Science ®Google Scholar
• Zanda G, Franciosi P, Tognoni G, Rizzo M, Standen SM, Morselli PL, Garattini S. 1973. A double blind study on the effects of monosodium glutamate in man. Biomedicine. 19:202–204.
   PubMedGoogle Scholar