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Research Articles

Acute promyelocytic leukemia drug – arsenic trioxide in the presence of eugenol shows differential action on leukemia cells (HL-60) and cardiomyocytes (H9c2) – inference from NMR study

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Pages 457-466 | Received 15 Jan 2021, Accepted 02 Apr 2021, Published online: 20 Apr 2021

References

  • Abhilash S, Siviyasankar R, Binu P, Arathi P, Harikumaran Nair R. 2018. Different administration patterns of docosahexaenoic acid in combating cytotoxic manifestations due to arsenic trioxide (acute promyelocytic leukemia drug) induced redox imbalance in hepatocytes. Prostaglandins Other Lipid Mediat. 136:64–75.
  • Asha MK, Prashanth D, Murali B, Padmaja R, Amit A. 2001. Anthelmintic activity of essential oil of Ocimum sanctum and eugenol. Fitoterapia. 72:669–670.
  • Bagur R, Souza A, Gunther G, Reif R, Várnai P, Csordás G, Hajnóczky G. 2018. Arsenic targets local ROS and calcium homeostasis at the mitochondria-ER interface. Biophys J. 114:659a.
  • Bezerra DP, Militão GC, De Morais MC, De Sousa DP. 2017. The dual antioxidant/prooxidant effect of eugenol and its action in cancer development and treatment. Nutrients. 9:1367.
  • Binu P, Abhilash S, Vineetha RC, Arathi P Harikumaran N. 2018b. Protective role of eugenol on acute promyelocyte leukemia drug arsenic trioxide induced renal injury in Wistar rats. Indian J Physiol Pharmacol. 62:120–131.
  • Binu P, Gifty K, Vineetha RC, Abhilash S, Arathi P, Nair RH. 2018a. Eugenol, a plant-derived phenolic nutraceutical, protects thiol (SH) group in myocardium from ROS-mediated oxidation under chemotherapeutic stress induced by arsenic trioxide - a in vivo model study. Drug Chem Toxicol. 41:352–357.
  • Binu P, Harikumaran Nair R. 2015. Screening of eugenol-A monoterpene, as an antioxidant. Int J Adv Res. 3:1527–1533.
  • Binu P, Priya N, Abhilash S, Vineetha RC, Nair RH. 2017. Studies on curative efficacy of monoterpene eugenol on anti- leukemic drug arsenic trioxide induced cardiotoxicity. Biomed Pharmacother. 91:559–566.
  • Binu P, Priya NK, Abhilash S, Vineetha RC, Nair H. 2018c. Protective effects of eugenol against hepatotoxicity induced by arsenic trioxide: an antileukemic drug. Iran J Med Sci. 43:305–312.
  • Binu P, Varghese MV, Alex M, Abhilash S, Vineetha RC, Nair RH. 2016. The antioxidant potential of astaxanthin on arsenic trioxide induced cardiac damage in male Wistar rats. J Biotechnol Biochem. 2:42–48.
  • Chaudhari N, Talwar P, Parimisetty A, Lefebvre d'Hellencourt C, Ravanan P. 2014. A molecular web: endoplasmic reticulum stress, inflammation, and oxidative stress. Front Cell Neurosci. 29:213.
  • Chen Y, Li S, Zhou C, Li C, Ru K, Rao Q, Xing H, Tian Z, Tang K, Mi Y, et al. 2014. TBLR1 fuses to retinoid acid receptor α in a variant t(3;17)(q26;q21) translocation of acute promyelocytic leukemia. Blood. 124:936–945.
  • Ekinci Akdemir FN, Yildirim S, Kandemir FM, Aksu EH, Guler MC, Kiziltunc Ozmen H, Kucukler S, Eser G. 2019. The anti-apoptotic and antioxidant effects of eugenol against cisplatin‐induced testicular damage in the experimental model. Andrologia. 51:1–8.
  • Fouad AA, Yacoubi MT. 2011. Mechanisms underlying the protective effect of eugenol in rats with acute doxorubicin cardiotoxicity. Arch Pharm Res. 34:821–828.
  • Geraldes CF, Saraiva ME, Dias BA. 1992. Arsenic-75 nuclear magnetic resonance: study of the interaction of arsenate with various molecules of biological interest. J Inorg Biochem. 46:99–108.
  • Gerweck LE, Seetharaman K. 1996. Cellular pH gradient in tumor versus normal tissue: potential exploitation for the treatment of cancer. Cancer Res. 56:1194–1198.
  • Görlach A, Dimova EY, Petry A, Martínez-Ruiz A, Hernansanz-Agustín P, Rolo AP, Palmeira CM, Kietzmann T. 2015. Reactive oxygen species, nutrition, hypoxia, and diseases: problems solved? Redox Biol. 6:372–385.
  • Irie Y, Keung WM. 2003. Rhizoma acori graminei and its active principles protect PC-12 cells from the toxic effect of amyloid-beta peptide. Brain Res. 963:282–289.
  • Kabuto H, Tada M, Kohno M. 2007. Eugenol [2-methoxy-4-(2-propenyl)phenol] prevents 6-hydroxydopamine-induced dopamine depression and lipid peroxidation inductivity in mouse striatum. Biol Pharm Bull. 30:423–427.
  • Lee KG, Shibamoto T. 2002. Determination of antioxidant potential of volatile extracts isolated from various herbs and spices. J Agric Food Chem. 50:4947–4952.
  • Manikandan P, Murugan RS, Priyadarsini RV, Vinothini G, Nagini S. 2010. Eugenol induces apoptosis and inhibits invasion and angiogenesis in a rat model of gastric carcinogenesis induced by MNNG. Life Sci. 86:936–941.
  • Minamino T, Komuro I, Kitakaze M. 2010. Endoplasmic reticulum stress as a therapeutic target in cardiovascular disease. Circ Res. 107:1071–1082.
  • Oroojan AA, Chenani N, An’aam M. 2020. Antioxidant effects of eugenol on oxidative stress induced by hydrogen peroxide in islets of langerhans isolated from male mouse. Int J Hepatol. 2020:1–5.
  • Özdemir B, Shi B, Bantleon HP, Moritz A, Rausch-Fan X, Andrukhov O. 2014. Endocannabinoids and inflammatory response in periodontal ligament cells. PloS One. 9:e107407.
  • Pal D, Banerjee S, Mukherjee S, Roy A, Panda CK, Das S. 2010. Eugenol restricts DMBA croton oil induced skin carcinogenesis in mice: downregulation of c-Myc and H-ras, and activation of p53 dependent apoptotic pathway. J Dermatol Sci. 59:31–39.
  • Pavia DL, Lampman GM, Kriz GS, Vyvyan J. 2008. Introduction to spectroscopy cengage learning. Belmont, CA: Brooks/Cole.
  • Pavithra B. 2014. Eugenol – a review. J Pharm Sci Res. 6:153.
  • Percy J, Gailer J. 2008. Methylated trivalent arsenicglutathione complexes are more stable than their arsenite analog. Bioinorg Chem. doi: 10.1155/2008/539082.
  • Reiter A, Saussele S, Grimwade D, Wiemels JL, Segal MR, Lafage-Pochitaloff M, Walz C, Weisser A, Hochhaus A, Willer A, et al. 2003. Genomic anatomy of the specific reciprocal translocation t(15;17) in acute promyelocytic leukemia. Genes Chromosomes Cancer. 36:175–188.
  • Scott N, Hatlelid KM, MacKenzie NE, Carter DE. 1993. Reactions of arsenic(III) and arsenic(V) species with glutathione. Chem Res Toxicol. 6:102–106.
  • Shen Y, Shen ZX, Yan H, Chen J, Zeng XY, Li JM, Li XS, Wu W, Xiong SM, Zhao WL, et al. 2001. Studies on the clinical efficacy and pharmacokinetics of low-dose arsenic trioxide in the treatment of relapsed acute promyelocytic leukemia: a comparison with conventional dosage. Leukemia. 15:735–741.
  • Srivastava N, Majumder A, Rastogi S. 2019. Adverse drug reactions of anti-cancer drugs and its management: a review. Int J Adv Res Med Chem. 1:19–27.
  • Tao G, Irie Y, Li DJ, Keung WM. 2005. Eugenol and its structural analogs inhibit monoamine oxidase A and exhibit antidepressant-like activity. Bioorg Med Chem. 13:4777–4788.
  • Tiku AB, Abraham SK, Kale RK. 2004. Eugenol as an in vivo radioprotective agent. JRR. 45:435–440.
  • Varghese MV, Abhilash M, Paul MS, Alex M, Nair RH. 2017. Omega-3 fatty acid protects against arsenic trioxide-induced cardiotoxicity in vitro and in vivo. Cardiovasc Toxicol. 17:109–119.
  • Vineetha RC, Binu P, Arathi P, Nair RH. 2018. L-ascorbic acid and α-tocopherol attenuate arsenic trioxide-induced toxicity in H9c2 cardiomyocytes by the activation of Nrf2 and Bcl2 transcription factors. Toxicol Mech Methods. 28:353–360.
  • Wang H, Joseph JA. 1999. Quantifying cellular oxidative stress by dichlorofluorescein assay using microplate reader11Mention of a trade name, proprietary product, or specific equipment does not constitute a guarantee by the United States Department of Agriculture and does not imply its approval to the exclusion of other products that may be suitable. Free Radical Biol Med. 27:612–616.
  • Wang Y, Tang Z, Xue R, Singh GK, Shi K, Lv Y, Yang L. 2011. Combined effects of TNF‐α, IL‐1β, and HIF‐1α on MMP‐2 production in ACL fibroblasts under mechanical stretch: an in vitro study. J Orthop Res. 29:1008–1014.
  • Wani MR, Maheshwari N. Shadab. 2021. Eugenol attenuates TiO 2 nanoparticles-induced oxidative damage, biochemical toxicity, and DNA damage in Wistar rats: an in vivo study. Environ Sci Pollut Res. doi: https://doi.org/10.1007/s11356-020-12139-3.
  • Yi J, Gao F, Shi G, Li H, Wang Z, Shi X, Tang X. 2002. The inherent cellular level of reactive oxygen species: one of the mechanisms determining apoptotic susceptibility of leukemic cells to arsenic trioxide. Apoptosis. 7:209–215.
  • Yogalakshmi B, Viswanathan P, Anuradha CV. 2010. Investigation of antioxidant, anti-inflammatory and DNA-protective properties of eugenol in thioacetamide-induced liver injury in rats. Toxicology. 268:204–212.
  • Zhang JH, Zhang Y, Herman B. 2003. Caspases, apoptosis and aging. Ageing Res Rev. 2:357–366.

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