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Research Articles

Attenuation of experimentally induced atopic dermatitis in mice by sulforaphane: effect on inflammation and apoptosis

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Pages 224-232 | Received 26 Apr 2021, Accepted 09 Oct 2021, Published online: 07 Nov 2021

References

  • Alshevskaya AA, Lopatnikova JA, Krugleeva OL, Nepomnyschih VM, Lukinov VL, Karaulov AV, Sennikov SV. 2016. Expression density of receptors to IL-1β in atopic dermatitis. Mol Immunol. 75:92–100.
  • Alyoussef A. 2015a. Arjunolic acid protects against DNCB-induced atopic dermatitis-like symptoms in mice by restoring a normal cytokine balance. Eur Cytokine Netw. 26(2):38–45.
  • Alyoussef A. 2015b. Suramin attenuated inflammation and reversed skin tissue damage in experimentally induced atopic dermatitis in mice. Inflamm Allergy Drug Targets. 13(6):406–410.
  • Alyoussef A. 2018. Blocking TGF-β type 1 receptor partially reversed skin tissue damage in experimentally induced atopic dermatitis in mice. Cytokine. 106:45–53.
  • Alyoussef A. 2021. The therapeutic effects of blocking IGF-R1 on mice model of skin cancer. J Dermatol Treat. 32(7):803–809.
  • Arita Y, Jeong Park H, Cantillon A, Verma K, Menon R, Getahun D, Peltier MR. 2019. Pro- and anti-inflammatory effects of sulforaphane on placental cytokine production. J Reprod Immunol. 131:44–49.
  • Arshad SH, Holgate S. 2001. The role of IgE in allergen-induced inflammation and the potential for intervention with a humanized monoclonal anti-IgE antibody. Clin Exp Allergy. 31(9):1344–1351.
  • Bao L, Chau CS, Lei Z, Hu H, Chan AG, Amber KT, Maienschein-Cline M, Tsoukas MM. 2021. Dysregulated microRNA expression in IL-4 transgenic mice, an animal model of atopic dermatitis. Arch Dermatol Res.313(10):837–846.
  • Bieber T. 2008. Atopic dermatitis. N Engl J Med. 358(14):1483–1494.
  • Boguniewicz M, Alexis AF, Beck LA, Block J, Eichenfield LF, Fonacier L, Guttman-Yassky E, Paller AS, Pariser D, Silverberg JI, et al. 2017. Expert perspectives on management of moderate-to-severe atopic dermatitis: a multidisciplinary consensus addressing current and emerging therapies. J Allergy Clin Immunol Pract. 5(6):1519–1531.
  • Boguniewicz M, Leung DY. 2011. Atopic dermatitis: a disease of altered skin barrier and immune dysregulation. Immunol Rev. 242(1):233–246.
  • Brunner PM, Silverberg JI, Guttman-Yassky E, Paller AS, Kabashima K, Amagai M, Luger TA, Deleuran M, Werfel T, Eyerich K, et al. 2017. Increasing comorbidities suggest that atopic dermatitis is a systemic disorder. J Invest Dermatol. 137(1):18–25.
  • Caglayan Sozmen S, Karaman M, Cilaker Micili S, Isik S, Arikan Ayyildiz Z, Bagriyanik A, Uzuner N, Karaman O. 2016. Resveratrol ameliorates 2,4-dinitrofluorobenzene-induced atopic dermatitis-like lesions through effects on the epithelium. PeerJ. 4:e1889.
  • Dinkova-Kostova AT, Jenkins SN, Fahey JW, Ye L, Wehage SL, Liby KT, Stephenson KK, Wade KL, Talalay P. 2006. Protection against UV-light-induced skin carcinogenesis in SKH-1 high-risk mice by sulforaphane-containing broccoli sprout extracts. Cancer Lett. 240(2):243–252.
  • Jeong SI, Choi BM, Jang SI. 2010. Sulforaphane suppresses TARC/CCL17 and MDC/CCL22 expression through heme oxygenase-1 and NF-κB in human keratinocytes. Arch Pharm Res. 33(11):1867–1876.
  • Jun SR, Cheema A, Bose C, Boerma M, Palade PT, Carvalho E, Awasthi S, Singh SP. 2020. Multi-omic analysis reveals different effects of sulforaphane on the microbiome and metabolome in old compared to young mice. Microorganisms. 8(10):1500.
  • Kim CG, Kang M, Lee YH, Min WG, Kim YH, Kang SJ, Song CH, Park SJ, Park JH, Han CH, et al. 2015. Bathing effects of various seawaters on allergic (atopic) dermatitis-like skin lesions induced by 2,4-dinitrochlorobenzene in hairless mice. Evid Based Complement Alternat Med. 2015:179185.
  • Kim JE, Sharma A, Sharma G, Lee SY, Shin HS, Rudra D, Im SH. 2019. Lactobacillus pentosus modulates immune response by inducing IL-10 producing Tr1 cells. Immune Netw. 19(6):e39.
  • Li S, Yang Y, Sargsyan D, Wu R, Yin R, Kuo HD, Yang I, Wang L, Cheng D, Ramirez CN, et al. 2020. Epigenome, transcriptome, and protection by sulforaphane at different stages of UVB-induced skin carcinogenesis. Cancer Prev Res. 13(6):551–562.
  • Li Y, Zhang T, Li X, Zou P, Schwartz SJ, Sun D. 2013. Kinetics of sulforaphane in mice after consumption of sulforaphane-enriched broccoli sprout preparation. Mol Nutr Food Res. 57(12):2128–2136.
  • Liu Y, Zhang Z, Lu X, Meng J, Qin X, Jiang J. 2020. Anti-nociceptive and anti-inflammatory effects of sulforaphane on sciatic endometriosis in a rat model. Neurosci Lett. 723:134858.
  • Nedoszytko B, Sokołowska-Wojdyło M, Ruckemann-Dziurdzińska K, Roszkiewicz J, Nowicki RJ. 2014. Chemokines and cytokines network in the pathogenesis of the inflammatory skin diseases: atopic dermatitis, psoriasis and skin mastocytosis. Postepy Dermatol Alergol. 31(2):84–91.
  • Ott H, Stanzel S, Ocklenburg C, Merk HF, Baron JM, Lehmann S. 2009. Total serum IgE as a parameter to differentiate between intrinsic and extrinsic atopic dermatitis in children. Acta Derm Venereol. 89(3):257–261.
  • Pandher K, Patel K, Wang JV, Saedi N. 2021. The other side of atopic dermatitis: an evaluation of psychosocial comorbidities. Clin Dermatol. 39(2):296–298.
  • Park JY, Park HJ, Choi YY, Kim MH, Kim SN, Yang WM. 2013. Effects of acupuncture on 1-chloro-2,4-dinitrochlorobenzene-induced atopic dermatitis. Evid Based Complement Alternat Med. 2013:982095.
  • Peroni DG, Bodini A, Corradi M, Coghi A, Boner AL, Piacentini GL. 2012. Markers of oxidative stress are increased in exhaled breath condensates of children with atopic dermatitis. Br J Dermatol. 166(4):839–843.
  • Qin S, Yang C, Huang W, Du S, Mai H, Xiao J, Lu T. 2018. Sulforaphane attenuates microglia-mediated neuronal necroptosis through down-regulation of MAPK/NF-κB signaling pathways in LPS-activated BV-2 microglia. Pharmacol Res. 133:218–235.
  • Ranaweera SS, Dissanayake CY, Natraj P, Lee YJ, Han CH. 2020. Anti-inflammatory effect of sulforaphane on LPS-stimulated RAW 264.7 cells and ob/ob mice. J Vet Sci. 21(6):e91.
  • Ren X, Xu Y, Yu Z, Mu C, Liu P, Li J. 2021. The role of Nrf2 in mitigating cadmium-induced oxidative stress of Marsupenaeus japonicus. Environ Pollut. 269:116112.
  • Sarkar R, Kanwar AJ. 2002. Atopic dermatitis. Indian Pediatr. 39(10):922–930.
  • Shibata A, Nakagawa K, Yamanoi H, Tsuduki T, Sookwong P, Higuchi O, Kimura F, Miyazawa T. 2010. Sulforaphane suppresses ultraviolet B-induced inflammation in HaCaT keratinocytes and HR-1 hairless mice. J Nutr Biochem. 21(8):702–709.
  • Sivaranjani N, Rao SV, Rajeev G. 2013. Role of reactive oxygen species and antioxidants in atopic dermatitis. J Clin Diagn Res. 7(12):2683–2685.
  • Subedi L, Lee JH, Yumnam S, Ji E, Kim SY. 2019. Anti-inflammatory effect of sulforaphane on LPS-activated microglia potentially through JNK/AP-1/NF-kappaB inhibition and Nrf2/HO-1 activation. Cells. 8(2):194.
  • Tang L, Ren X, Han Y, Chen L, Meng X, Zhang C, Chu H, Kong L, Ma H. 2020. Sulforaphane attenuates apoptosis of hippocampal neurons induced by high glucose via regulating endoplasmic reticulum. Neurochem Int. 136:104728.
  • Thestrup-Pedersen K. 2000. Clinical aspects of atopic dermatitis. Clin Exp Dermatol. 25(7):535–543.
  • Torres T, Ferreira EO, Goncalo M, Mendes-Bastos P, Selores M, Filipe P. 2019. Update on atopic dermatitis. Acta Med Port. 32(9):606–613.
  • Ungar B, Garcet S, Gonzalez J, Dhingra N, Correa da Rosa J, Shemer A, Krueger JG, Suarez-Farinas M, Guttman-Yassky E. 2017. An integrated model of atopic dermatitis biomarkers highlights the systemic nature of the disease. J Invest Dermatol. 137(3):603–613.
  • Weidinger S, Beck LA, Bieber T, Kabashima K, Irvine AD. 2018. Atopic dermatitis. Nat Rev Dis Primers. 4(1):1.
  • Wollenberg A, Folster-Holst R, Saint Aroman M, Sampogna F, Vestergaard C. 2018. Effects of a protein-free oat plantlet extract on microinflammation and skin barrier function in atopic dermatitis patients. J Eur Acad Dermatol Venereol. 32(Suppl 1):1–15.
  • Wu DM, Zheng ZH, Fan SH, Zhang ZF, Chen GQ, Lu J. 2020. Sulforaphane administration alleviates diffuse axonal injury (DAI) via regulation signaling pathway of NRF2 and HO-1. J Cell Biochem. 121(1):430–442.
  • Wu W, Peng G, Yang F, Zhang Y, Mu Z, Han X. 2019. Sulforaphane has a therapeutic effect in an atopic dermatitis murine model and activates the Nrf2/HO1 axis. Mol Med Rep. 20(2):1761–1771.
  • Yamazaki Y, Nakamura Y, Nunez G. 2017. Role of the microbiota in skin immunity and atopic dermatitis. Allergol Int. 66(4):539–544.
  • Yang D, Han B, Baiyun R, Lv Z, Wang X, Li S, Lv Y, Xue J, Liu Y, Zhang Z. 2020. Sulforaphane attenuates hexavalent chromium-induced cardiotoxicity via the activation of the Sesn2/AMPK/Nrf2 signaling pathway. Metallomics. 12(12):2009–2020.

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