Identification of differentially expressed genes and pathways in diquat and paraquat poisoning using bioinformatics analysis

References

• Benelli R, Venè R, Ferrari N. 2018. Prostaglandin-endoperoxide synthase 2 (cyclooxygenase-2), a complex target for colorectal cancer prevention and therapy. Transl Res. 196:42–61.
   PubMed Web of Science ®Google Scholar
• Cao Y, Li J, Ou Z, Yin Z, Chen X, Han Y, Song W. 2015. Inhibition of pulmonary nuclear factor -ΚB and tumor necrosis factor -α expression by diallyl sulfide in rats with paraquat poisoning. Zhonghua Wei Zhong Bing ji Jiu yi Xue. 27(4):274–279.
   PubMedGoogle Scholar
• Chen C, Chen H, Zhang Y, Thomas HR, Frank MH, He Y, Xia R. 2020. TBtools: an integrative toolkit developed for interactive analyses of big biological data. Mol Plant. 13(8):1194–1202.
   PubMed Web of Science ®Google Scholar
• Choi SE, Park YS, Koh HC. 2018. NF-κB/p53-activated inflammatory response involves in diquat-induced mitochondrial dysfunction and apoptosis. Environ Toxicol. 33(10):1005–1018.
   PubMed Web of Science ®Google Scholar
• Cui D, Xiao J, Zhou Y, Zhou X, Liu Y, Peng Y, Yu Y, Li H, Zhou X, Yuan Q, et al. 2019. Epiregulin enhances odontoblastic differentiation of dental pulp stem cells via activating MAPK signalling pathway. Cell Prolif. 52(6):e12680.
   PubMed Web of Science ®Google Scholar
• Cui S, Nian Q, Chen G, Wang X, Zhang J, Qiu J, Zhang Z. 2019. Ghrelin ameliorates A549 cell apoptosis caused by paraquat via p38-MAPK regulated mitochondrial apoptotic pathway. Toxicology. 426:152267.
   PubMed Web of Science ®Google Scholar
• Davis M, Stamper BD. 2016. TAMH: a useful in vitro model for assessing hepatotoxic mechanisms. Biomed Res Int. 2016:4780872.
   PubMed Web of Science ®Google Scholar
• Day RB, Link DC. 2012. Regulation of neutrophil trafficking from the bone marrow. Cell Mol Life Sci. 69(9):1415–1423. eng.
   PubMed Web of Science ®Google Scholar
• Fortenberry GZ, Beckman J, Schwartz A, Prado JB, Graham LS, Higgins S, Lackovic M, Mulay P, Bojes H, Waltz J, et al. 2016. Magnitude and characteristics of acute paraquat- and diquat-related illnesses in the US: 1998-2013. Environ Res. 146:191–199.
   PubMed Web of Science ®Google Scholar
• Hai T, Jalgaonkar S, Wolford CC, Yin X. 2011. Immunohistochemical detection of activating transcription factor 3, a hub of the cellular adaptive-response network. Methods Enzymol. 490:175–194.
   PubMed Web of Science ®Google Scholar
• Hansen PJ, Dobbs KB, Denicol AC. 2014. Programming of the preimplantation embryo by the embryokine colony stimulating factor 2. Anim Reprod Sci. 149(1-2):59–66.
   PubMed Web of Science ®Google Scholar
• Huang M, Huang NN, Li YY, Wu KX, Guo MZ, Zhu CD. 2019. [Effects of paraquat on the proliferation of human neural stem cells via DNA methylation]. Zhonghua Lao Dong Wei Sheng Zhi ye Bing za Zhi = Zhonghua Laodong Weisheng Zhiyebing Zazhi = Chinese J Indust Hygiene Occup Dis. 37(3):161–168.
   PubMedGoogle Scholar
• Jaén RI, Prieto P, Casado M, Martín-Sanz P, Boscá L. 2018. Post-translational modifications of prostaglandin-endoperoxide synthase 2 in colorectal cancer: an update. World J Gastroenterol. 24(48):5454–5461.
   PubMed Web of Science ®Google Scholar
• Johnson GL, Dohlman HG, Graves LM. 2005. MAPK kinase kinases (MKKKs) as a target class for small-molecule inhibition to modulate signaling networks and gene expression. Curr Opin Chem Biol. 9(3):325–331.
   PubMed Web of Science ®Google Scholar
• Jones GM, Vale JA. 2000. Mechanisms of toxicity, clinical features, and management of diquat poisoning: a review. J Toxicol Clin Toxicol. 38(2):123–128.
   PubMed Web of Science ®Google Scholar
• Ju DT, Sivalingam K, Kuo WW, Ho TJ, Chang RL, Chung LC, Day CH, Viswanadha VP, Liao PH, Huang CY. 2019. Effect of vasicinone against paraquat-induced MAPK/p53-mediated apoptosis via the IGF-1R/PI3K/AKT pathway in a Parkinson's disease-associated SH-SY5Y cell model. Nutrients. 11(7):1655.
   Web of Science ®Google Scholar
• Kobayashi Y. 2008. The role of chemokines in neutrophil biology. Front Biosci. 13:2400–2407.
   PubMed Web of Science ®Google Scholar
• Litteljohn D, Mangano EN, Hayley S. 2008. Cyclooxygenase-2 deficiency modifies the neurochemical effects, motor impairment and co-morbid anxiety provoked by paraquat administration in mice. Eur J Neurosci. 28(4):707–716.
   PubMed Web of Science ®Google Scholar
• Lou N, Lennard Richard ML, Yu J, Kindy M, Zhang XK. 2017. The Fli-1 transcription factor is a critical regulator for controlling the expression of chemokine C-X-C motif ligand 2 (CXCL2). Mol Immunol. 81:59–66.
   PubMed Web of Science ®Google Scholar
• Lu S, Gao D, Wang Y, Feng X, Zhang Y, Li L, Geng Z. 2021. Development and validation of a radiomics nomogram for prognosis prediction of patients with acute paraquat poisoning: a retrospective cohort study. Biomed Res Int. 2021:6621894.
   PubMed Web of Science ®Google Scholar
• Magalhães N, Carvalho F, Dinis-Oliveira RJ. 2018. Human and experimental toxicology of diquat poisoning: Toxicokinetics, mechanisms of toxicity, clinical features, and treatment. Hum Exp Toxicol. 37(11):1131–1160.
   PubMed Web of Science ®Google Scholar
• Malekinejad H, Rezabakhsh A, Rahmani F, Razi M. 2013. Paraquat exposure up-regulates cyclooxygenase-2 in the lungs, liver and kidneys in rats. Iran J Pharm Res. 12(4):887–896.
   PubMed Web of Science ®Google Scholar
• McCarthy LG, Speth CP. 1983. Diquat intoxication. Ann Emerg Med. 12(6):394–396.
   PubMed Web of Science ®Google Scholar
• Mitchell JA, Kirkby NS. 2019. Eicosanoids, prostacyclin and cyclooxygenase in the cardiovascular system. Br J Pharmacol. 176(8):1038–1050.
   PubMed Web of Science ®Google Scholar
• Mitra S, Chakrabarti N, Bhattacharyya A. 2011. Differential regional expression patterns of α-synuclein, TNF-α, and IL-1β; and variable status of dopaminergic neurotoxicity in mouse brain after Paraquat treatment. J Neuroinflammation. 8:163.
   PubMed Web of Science ®Google Scholar
• World Health and International Programme on Chemical 2004. The WHO recommended classification of pesticides by hazard and guidelines to classification. Geneva: World Health Organization.
   Google Scholar
• Shyam S, Goel P, Kumar D, Malpotra S, Singh MK, Lathwal SS, Chand S, Palta P. 2020. Effect of Dickkopf-1 and colony stimulating factor-2 on the developmental competence, quality, gene expression and live birth rate of buffalo (Bubalus bubalis) embryos produced by hand-made cloning. Theriogenology. 157:254–262.
   PubMed Web of Science ®Google Scholar
• Singh S, Gupta SK, Seth PK. 2018. Biomarkers for detection, prognosis and therapeutic assessment of neurological disorders. Rev Neurosci. 29(7):771–789.
   PubMed Web of Science ®Google Scholar
• SreeHarsha N. 2020. Embelin impact on paraquat-induced lung injury through suppressing oxidative stress, inflammatory cascade, and MAPK/NF-κB signaling pathway. J Biochem Mol Toxicol. 34(4):e22456.
   PubMed Web of Science ®Google Scholar
• Stamper BD, Bammler TK, Beyer RP, Farin FM, Nelson SD. 2010. Differential regulation of mitogen-activated protein kinase pathways by acetaminophen and its nonhepatotoxic regioisomer 3'-hydroxyacetanilide in TAMH cells. Toxicol Sci. 116(1):164–173.
   PubMed Web of Science ®Google Scholar
• Sun B, He Y. 2017. [Paraquat poisoning mechanism and its clinical treatment progress]. Zhonghua Wei Zhong Bing ji Jiu yi Xue. 29(11):1043–1046.
   PubMedGoogle Scholar
• Thompson MR, Xu D, Williams BR. 2009. ATF3 transcription factor and its emerging roles in immunity and cancer. J Mol Med (Berl). 87(11):1053–1060.
   PubMed Web of Science ®Google Scholar
• Tríbulo P, Siqueira LGB, Oliveira LJ, Scheffler T, Hansen PJ. 2018. Identification of potential embryokines in the bovine reproductive tract. J Dairy Sci. 101(1):690–704.
   PubMed Web of Science ®Google Scholar
• Vale JA, Meredith TJ, Buckley BM. 1987. Paraquat poisoning: clinical features and immediate general management. Hum Toxicol. 6(1):41–47. eng.
   PubMedGoogle Scholar
• Wang Y, Tang H, Debarry JD, Tan X, Li J, Wang X, Lee TH, Jin H, Marler B, Guo H, et al. 2012. MCScanX: a toolkit for detection and evolutionary analysis of gene synteny and collinearity. Nucleic Acids Res. 40(7):e49.
   PubMed Web of Science ®Google Scholar
• Wang YL, Zheng J, Zhang XF, Zhang Y. 2020. Attenuation of paraquat-induced inflammation by inhibitors of phosphorylation of mitogen-activated protein kinases in BV2 microglial cells. J Neurol Sci. 410:116679.
   PubMed Web of Science ®Google Scholar
• Xing J, Chu Z, Han D, Jiang X, Zang X, Liu Y, Gao S, Sun L. 2020. Lethal diquat poisoning manifesting as central pontine myelinolysis and acute kidney injury: a case report and literature review. J Int Med Res. 48(7):300060520943824. 300060520943824.
   PubMed Web of Science ®Google Scholar
• Yang CJ, Yang J, Fan ZX, Yang J. 2016. Activating transcription factor 3-an endogenous inhibitor of myocardial ischemia-reperfusion injury (Review). Mol Med Rep. 13(1):9–12.
   PubMed Web of Science ®Google Scholar
• Yang W, Tiffany-Castiglioni E, Lee MY, Son IH. 2010. Paraquat induces cyclooxygenase-2 (COX-2) implicated toxicity in human neuroblastoma SH-SY5Y cells. Toxicol Lett. 199(3):239–246.
   PubMed Web of Science ®Google Scholar
• Zhu J, Yu Y, Li H, Zheng F, Lin R, Yang C. 2018. Effect of sucralfate on cytokines in rat with paraquat poisoning. Zhonghua Wei Zhong Bing ji Jiu yi Xue. 30(3):220–223.
   PubMedGoogle Scholar