Aurintricarboxylic acid mitigates cigarette smoke extract induced oxidative stress and pulmonary inflammation via inhibition of NF-ҡB/p65 signaling

References

• Abboud R, Vimalanathan S. 2008. Pathogenesis of COPD. Part I. The role of protease-antiprotease imbalance in emphysema [State of the Art Series. Chronic obstructive pulmonary disease in high-and low-income countries. Edited by G. Marks and M. Chan-Yeung. Number 3 in the series]. Int J Tuberc Lung Dis. 12(4):361–367.
   PubMed Web of Science ®Google Scholar
• Abernathy LM, Fountain MD, Rothstein SE, David JM, Yunker CK, Rakowski J, Lonardo F, Joiner MC, Hillman GG. 2015. Soy isoflavones promote radioprotection of normal lung tissue by inhibition of radiation-induced activation of macrophages and neutrophils. J Thorac Oncol. 10(12):1703–1712.
   PubMed Web of Science ®Google Scholar
• Andrew DJ, Hay AW, Evans SW. 1999. Aurintricarboxylic acid inhibits apoptosis and supports proliferation in a haemopoietic growth-factor dependent myeloid cell line. Immunopharmacology. 41(1):1–10.
   PubMedGoogle Scholar
• Basak S, Behar M, Hoffmann A. 2012. Lessons from mathematically modeling the NF‐κB pathway. Immunol Rev. 246(1):221–238.
   PubMedGoogle Scholar
• Blumenthal T, Landers TA. 1973. The inhibition of nucleic acid-binding proteins by aurintricarboxylic acid. Biochem Biophys Res Commun. 55(3):680–688.
   PubMed Web of Science ®Google Scholar
• Brain JD, Knudson DE, Sorokin SP, Davis MA. 1976. Pulmonary distribution of particles given by intratracheal instillation or by aerosol inhalation. Environ Res. 11(1):13–33.
   PubMed Web of Science ®Google Scholar
• Bruin JE, Petre MA, Raha S, Morrison KM, Gerstein HC, Holloway AC. 2008. Fetal and neonatal nicotine exposure in Wistar rats causes progressive pancreatic mitochondrial damage and beta cell dysfunction. PLOS One. 3(10):e3371.
   PubMed Web of Science ®Google Scholar
• Brusselle GG, Joos GF, Bracke KR. 2011. New insights into the immunology of chronic obstructive pulmonary disease. Lancet. 378(9795):1015–1026.
   PubMed Web of Science ®Google Scholar
• Cappuccini F, Eldh T, Bruder D, Gereke M, Jastrow H, Schulze-Osthoff K, Fischer U, Köhler D, Stuschke M, Jendrossek V. 2011. New insights into the molecular pathology of radiation-induced pneumopathy. Radiother Oncol. 101(1):86–92.
   PubMed Web of Science ®Google Scholar
• Daijo H, Hoshino Y, Kai S, Suzuki K, Nishi K, Matsuo Y, Harada H, Hirota K. 2016. Cigarette smoke reversibly activates hypoxia-inducible factor 1 in a reactive oxygen species-dependent manner. Sci Rep. 6:34424.
   PubMed Web of Science ®Google Scholar
• De Smet EG, Van Eeckhoutte HP, Avila Cobos F, Blomme E, Verhamme FM, Provoost S, Verleden SE, Venken K, Maes T, Joos GF, et al. 2020. The role of miR-155 in cigarette smoke-induced pulmonary inflammation and COPD. Mucosal Immunol. 13(3):423–436.
   PubMed Web of Science ®Google Scholar
• Demedts IK, Demoor T, Bracke KR, Joos GF, Brusselle GG. 2006. Role of apoptosis in the pathogenesis of COPD and pulmonary emphysema. Respir Res. 7(1):10–53.
   PubMedGoogle Scholar
• Dorrington MG, Fraser ID. 2019. NF-κB signaling in macrophages: dynamics, crosstalk, and signal integration. Front Immunol. 10:705.
   PubMed Web of Science ®Google Scholar
• Gindele JA, Kiechle T, Benediktus K, Birk G, Brendel M, Heinemann F, Wohnhaas CT, LeBlanc M, Zhang H, Strulovici-Barel Y, et al. 2020. Intermittent exposure to whole cigarette smoke alters the differentiation of primary small airway epithelial cells in the air-liquid interface culture. Sci Rep. 10(1):1–17.
   PubMed Web of Science ®Google Scholar
• Guan R, Cai Z, Wang J, Ding M, Li Z, Xu J, Li Y, Li J, Yao H, Liu W, et al. 2019. Hydrogen sulfide attenuates mitochondrial dysfunction-induced cellular senescence and apoptosis in alveolar epithelial cells by upregulating sirtuin 1. Aging. 11(24):11844–11864.
   PubMedGoogle Scholar
• Harrison OJ, Foley J, Bolognese BJ, Long IIIE, Podolin PL, Walsh PT. 2008. Airway infiltration of CD4+ CCR6+ Th17 type cells associated with chronic cigarette smoke induced airspace enlargement. Immunol Lett. 121(1):13–21.
   PubMed Web of Science ®Google Scholar
• Hashem AM, Flaman AS, Farnsworth A, Brown EG, Van Domselaar G, He R, Li X. 2009. Aurintricarboxylic acid is a potent inhibitor of influenza A and B virus neuraminidases. PLOS One. 4(12):e8350.
   PubMed Web of Science ®Google Scholar
• He R, Adonov A, Traykova-Adonova M, Cao J, Cutts T, Grudesky E, Deschambaul Y, Berry J, Drebot M, Li X. 2004. Potent and selective inhibition of SARS coronavirus replication by aurintricarboxylic acid. Biochem Biophys Res Commun. 320(4):1199–1203.
   PubMed Web of Science ®Google Scholar
• He Z-H, Chen P, Chen Y, He S-D, Ye J-R, Zhang H-L, Cao J. 2015. Comparison between cigarette smoke-induced emphysema and cigarette smoke extract-induced emphysema. Tob Induc Dis. 13(1):6.
   PubMed Web of Science ®Google Scholar
• Hop HT, Reyes AW, Huy TX, Arayan LT, Min W, Lee HJ, Rhee MH, Chang HH, Kim S. 2017. Activation of NF-kB-mediated TNF-induced antimicrobial immunity is required for the efficient Brucella abortus clearance in RAW 264.7 cells. Front Cell Infect Microbiol. 7:437.
   PubMed Web of Science ®Google Scholar
• Hsieh H-L, Wang H-H, Wu W-B, Chu P-J, Yang C-M. 2010. Transforming growth factor-β1 induces matrix metalloproteinase-9 and cell migration in astrocytes: roles of ROS-dependent ERK-and JNK-NF-κB pathways. J Neuroinflammation. 7(1):88.
   PubMed Web of Science ®Google Scholar
• Imai K, Mercer B, Schulman L, Sonett J, D'Armiento J. 2005. Correlation of lung surface area to apoptosis and proliferation in human emphysema. Eur Respir J. 25(2):250–258.
   PubMed Web of Science ®Google Scholar
• Ježek J, Cooper KF, Strich R. 2018. Reactive oxygen species and mitochondrial dynamics: the yin and yang of mitochondrial dysfunction and cancer progression. Antioxidants. 7(1):13.
   Web of Science ®Google Scholar
• Jin Y, Liu X, Liu H, Chen S, Gao C, Ge K, Zhang C, Zhang J. 2017. Oxidative stress-induced apoptosis of osteoblastic MC3T3-E1 cells by hydroxyapatite nanoparticles through lysosomal and mitochondrial pathways. RSC Adv. 7(21):13010–13018.
   Web of Science ®Google Scholar
• John M, Hoernig S, Doehner W, Okonko DD, Witt C, Anker SD. 2005. Anemia and inflammation in COPD. Chest. 127(3):825–829.
   PubMed Web of Science ®Google Scholar
• Keusch S, Hildenbrand FF, Bollmann T, Halank M, Held M, Kaiser R, Kovacs G, Lange TJ, Seyfarth H-J, Speich R, et al. 2014. Tobacco smoke exposure in pulmonary arterial and thromboembolic pulmonary hypertension. Respiration. 88(1):38–45.
   PubMed Web of Science ®Google Scholar
• Kirkham PA, Barnes PJ. 2013. Oxidative stress in COPD. Chest. 144(1):266–273.
   PubMed Web of Science ®Google Scholar
• Kuban-Jankowska A, Sahu KK, Gorska-Ponikowska M, Tuszynski JA, Wozniak M. 2017. Inhibitory activity of iron chelators ATA and DFO on MCF-7 breast cancer cells and phosphatases PTP1B and SHP2. Anticancer Res. 37(9):4799–4806.
   PubMed Web of Science ®Google Scholar
• Lateef A, Rehman MU, Tahir M, Khan R, Khan AQ, Qamar W, Sultana S. 2013. Farnesol protects against intratracheally instilled cigarette smoke extract-induced histological alterations and oxidative stress in prostate of Wistar rats. Toxicol Int. 20(1):35–42.
   PubMedGoogle Scholar
• Laufenberg L, Kazi AA, Lang CH. 2014. Salutary effect of aurintricarboxylic acid (ATA) on endotoxin-and sepsis-induced changes in muscle protein synthesis and inflammation. Shock. 41(5):420–428.
   PubMed Web of Science ®Google Scholar
• Lee J-W, Ryu HW, Park S-Y, Park HA, Kwon O-K, Yuk HJ, Shrestha KK, Park M, Kim JH, Lee S, et al. 2017. Protective effects of neem (Azadirachta indica A. Juss.) leaf extract against cigarette smoke-and lipopolysaccharide-induced pulmonary inflammation. Int J Mol Med. 40(6):1932–1940.
   PubMed Web of Science ®Google Scholar
• Liu X, Kohyama T, Kobayashi T, Abe S, Kim HJ, Reed EC, Rennard SI. 2003. Cigarette smoke extract inhibits chemotaxis and collagen gel contraction mediated by human bone marrow osteoprogenitor cells and osteoblast-like cells. Osteoporos Int. 14(3):235–242.
   PubMed Web of Science ®Google Scholar
• Maritz GS. 2013. Perinatal exposure to nicotine and implications for subsequent obstructive lung disease. Paediatr Respir Rev. 14(1):3–8.
   PubMed Web of Science ®Google Scholar
• Maurer HH. 2006. Hyphenated mass spectrometric techniques—indispensable tools in clinical and forensic toxicology and in doping control. J Mass Spectrom. 41(11):1399–1413.
   PubMed Web of Science ®Google Scholar
• Moniruzzaman M, Ghosal I, Das D, Chakraborty SB. 2018. Melatonin ameliorates H2O2-induced oxidative stress through modulation of Erk/Akt/NFkB pathway. Biol Res. 51(1):1–10.
   PubMedGoogle Scholar
• Myskiw C, Deschambault Y, Jefferies K, He R, Cao J. 2007. Aurintricarboxylic acid inhibits the early stage of vaccinia virus replication by targeting both cellular and viral factors. J Virol. 81(6):3027–3032.
   PubMed Web of Science ®Google Scholar
• Nicoletti I, Migliorati G, Pagliacci M, Grignani F, Riccardi C. 1991. A rapid and simple method for measuring thymocyte apoptosis by propidium iodide staining and flow cytometry. J Immunol Methods. 139(2):271–279.
   PubMed Web of Science ®Google Scholar
• Ontario Medical Association. 1999. Rethinking stop-smoking medications: myths and facts. Toronto, ON: Ontario Medical Association.
   Google Scholar
• Park J-G, Ávila-Pérez G, Madere F, Hilimire TA, Nogales A, Almazán F, Martínez-Sobrido L. 2019. Potent inhibition of zika virus replication by aurintricarboxylic acid. Front Microbiol. 10:718.
   PubMed Web of Science ®Google Scholar
• Rahman I, Adcock I. 2006. Oxidative stress and redox regulation of lung inflammation in COPD. Eur Respir J. 28(1):219–242.
   PubMed Web of Science ®Google Scholar
• Robinson AB, Johnson KD, Bennion BG, Reynolds PR. 2012. RAGE signaling by alveolar macrophages influences tobacco smoke-induced inflammation. Am J Physiol Lung Cell Mol Physiol. 302(11):L1192–L1199.
   PubMed Web of Science ®Google Scholar
• Roos A, Dhruv HD, Mathews IT, Inge LJ, Tuncali S, Hartman LK, Chow D, Millard N, Yin HH, Kloss J, et al. 2017. Identification of aurintricarboxylic acid as a selective inhibitor of the TWEAK-Fn14 signaling pathway in glioblastoma cells. Oncotarget. 8(7):12234–12246.
   PubMedGoogle Scholar
• Stewart ML, Grollman AP, Huang M-T. 1971. Aurintricarboxylic acid: inhibitor of initiation of protein synthesis. Proc Natl Acad Sci USA. 68(1):97–101.
   PubMed Web of Science ®Google Scholar
• Suki B, Bartolák-Suki E, Rocco PR. 2017. Elastase-induced lung emphysema models in mice. In Alpha-1 antitrypsin deficiency. New York, NY: Humana Press; p. 67–75.
   Google Scholar
• Tsi C-J, Chao Y, Chen C-W, Lin WW. 2002. Aurintricarboxylic acid protects against cell death caused by lipopolysaccharide in macrophages by decreasing inducible nitric-oxide synthase induction via IκB kinase, extracellular signal-regulated kinase, and p38 mitogen-activated protein kinase inhibition. Mol Pharmacol. 62(1):90–101.
   PubMed Web of Science ®Google Scholar
• Wyllie A, Morris R, Smith A, Dunlop D. 1984. Chromatin cleavage in apoptosis: association with condensed chromatin morphology and dependence on macromolecular synthesis. J Pathol. 142(1):67–77.
   PubMed Web of Science ®Google Scholar
• Yde P, Mengel B, Jensen MH, Krishna S, Trusina A. 2011. Modeling the NF-κB mediated inflammatory response predicts cytokine waves in tissue. BMC Syst Biol. 5(1):115–119.
   PubMedGoogle Scholar
• Zaken V, Kohen R, Ornoy A. 2001. Vitamins C and E improve rat embryonic antioxidant defense mechanism in diabetic culture medium. Teratology. 64(1):33–44.
   PubMedGoogle Scholar
• Zhang F, Wei W, Chai H, Xie X. 2013. Aurintricarboxylic acid ameliorates experimental autoimmune encephalomyelitis by blocking chemokine-mediated pathogenic cell migration and infiltration. J Immunol. 190(3):1017–1025.
   PubMed Web of Science ®Google Scholar
• Zou W, Zou Y, Zhao Z, Li B, Ran P. 2013. Nicotine-induced epithelial-mesenchymal transition via Wnt/β-catenin signaling in human airway epithelial cells. Am J Physiol Lung Cell Mol Physiol. 304(4):L199–L209.
   PubMed Web of Science ®Google Scholar
• Zuo L, He F, Sergakis GG, Koozehchian MS, Stimpfl JN, Rong Y, Diaz PT, Best TM. 2014. Interrelated role of cigarette smoking, oxidative stress, and immune response in COPD and corresponding treatments. Am J Physiol Lung Cell Mol Physiol. 307(3):L205–L218.
   PubMed Web of Science ®Google Scholar