158
Views
0
CrossRef citations to date
0
Altmetric
Research Articles

PM2.5 mediates mouse testis Sertoli TM4 cell damage by reducing cellular NAD+

, &
Pages 636-645 | Received 05 Mar 2023, Accepted 11 May 2023, Published online: 01 Jun 2023

References

  • Agarwal A, Baskaran S, Parekh N, Cho CL, Henkel R, Vij S, Arafa M, Panner Selvam MK, Shah R. 2021. Male infertility. Lancet. 397(10271):319–333.
  • Almeida S, Rato L, Sousa M, Alves MG, Oliveira PF. 2017. Fertility and sperm quality in the aging male. Curr Pharm Des. 23(30):4429–4437.
  • Anderson KA, Madsen AS, Olsen CA, Hirschey MD. 2017. Metabolic control by sirtuins and other enzymes that sense NAD(+), NADH, or their ratio. Biochim Biophys Acta Bioenerg. 1858(12):991–998.
  • Bai P, Canto C, Oudart H, Brunyanszki A, Cen Y, Thomas C, Yamamoto H, Huber A, Kiss B, Houtkooper RH, et al. 2011. PARP-1 inhibition increases mitochondrial metabolism through SIRT1 activation. Cell Metab. 13(4):461–468.
  • Bai X, Wang P. 2022. Relationship between sperm NAD + concentration and reproductive aging in normozoospermia men: a Cohort study. BMC Urol. 22(1):159.
  • Bertoldo MJ, Listijono DR, Ho WJ, Riepsamen AH, Goss DM, Richani D, Jin XL, Mahbub S, Campbell JM, Habibalahi A, et al. 2020. NAD(+) repletion rescues female fertility during reproductive aging. Cell Rep. 30(6):1670–1681 e1677.
  • Braidy N, Berg J, Clement J, Khorshidi F, Poljak A, Jayasena T, Grant R, Sachdev P. 2019. Role of nicotinamide adenine dinucleotide and related precursors as therapeutic targets for age-related degenerative diseases: rationale, biochemistry, pharmacokinetics, and outcomes. Antioxid Redox Signal. 30(2):251–294.
  • Brunet A, Sweeney LB, Sturgill JF, Chua KF, Greer PL, Lin Y, Tran H, Ross SE, Mostoslavsky R, Cohen HY, et al. 2004. Stress-dependent regulation of FOXO transcription factors by the SIRT1 deacetylase. Science. 303(5666):2011–2015.
  • Carre J, Gatimel N, Moreau J, Parinaud J, Leandri R. 2017. Does air pollution play a role in infertility?: a systematic review. Environ Health. 16(1):82.
  • Chen S, Wang S, Li T, Zhu H, Zhang Y, Liang S, Yang Y, Pan H, Shi X. 2022. Association between prenatal PM2.5 exposure and the risk of large for gestational age. Pediatr Res. 92(6):1773–1779.
  • Chen Y, Xi Y, Li M, Wu Y, Yan W, Dai J, Wu M, Ding W, Zhang J, Zhang F, et al. 2022. Maternal exposure to PM2.5 decreases ovarian reserve in neonatal offspring mice through activating PI3K/AKT/FoxO3a pathway and ROS-dependent NF-kappaB pathway. Toxicology. 481:153352.
  • Chu C, Zhang H, Cui S, Han B, Zhou L, Zhang N, Su X, Niu Y, Chen W, Chen R, et al. 2019. Ambient PM2.5 caused depressive-like responses through Nrf2/NLRP3 signaling pathway modulating inflammation. J Hazard Mater. 369:180–190.
  • Cohen MS. 2020. Interplay between compartmentalized NAD(+) synthesis and consumption: a focus on the PARP family. Genes Dev. 34(5-6):254–262.
  • Gerner RR, Klepsch V, Macheiner S, Arnhard K, Adolph TE, Grander C, Wieser V, Pfister A, Moser P, Hermann-Kleiter N, et al. 2018. NAD metabolism fuels human and mouse intestinal inflammation. Gut. 67(10):1813–1823.
  • Griswold MD. 1998. The central role of sertoli cells in spermatogenesis. Semin Cell Dev Biol. 9(4):411–416.
  • Hayes RB, Lim C, Zhang Y, Cromar K, Shao Y, Reynolds HR, Silverman DT, Jones RR, Park Y, Jerrett M, et al. 2020. PM2.5 air pollution and cause-specific cardiovascular disease mortality. Int J Epidemiol. 49(1):25–35.
  • Huang G, Zhang Q, Wu H, Wang Q, Chen Y, Guo P, Zhao Q. 2020. Sperm quality and ambient air pollution exposure: a retrospective, cohort study in a southern province of China. Environ Res. 188:109756.
  • Hwang ES, Song SB. 2017. Nicotinamide is an inhibitor of SIRT1 in vitro, but can be a stimulator in cells. Cell Mol Life Sci. 74(18):3347–3362.
  • Jankowska-Kieltyka M, Roman A, Nalepa I. 2021. The air we breathe: air pollution as a prevalent proinflammatory stimulus contributing to neurodegeneration. Front Cell Neurosci. 15:647643.
  • Leung M, Weisskopf MG, Laden F, Coull BA, Modest AM, Hacker MR, Wylie BJ, Wei Y, Schwartz J, Papatheodorou S. 2022. Exposure to PM2.5 during pregnancy and fetal growth in eastern Massachusetts, USA. Environ Health Perspect. 130(1):17004.
  • Li J, Dou X, Li S, Zhang X, Zeng Y, Song Z. 2015. Nicotinamide ameliorates palmitate-induced ER stress in hepatocytes via cAMP/PKA/CREB pathway-dependent Sirt1 upregulation. Biochim Biophys Acta. 1853(11 Pt A):2929–2936.
  • Liu F, Huang Y, Zhang F, Chen Q, Wu B, Rui W, Zheng JC, Ding W. 2015. Macrophages treated with particulate matter PM2.5 induce selective neurotoxicity through glutaminase-mediated glutamate generation. J Neurochem. 134(2):315–326.
  • Mann U, Shiff B, Patel P. 2020. Reasons for worldwide decline in male fertility. Curr Opin Urol. 30(3):296–301.
  • Martinez-Morcillo FJ, Canton-Sandoval J, Martinez-Navarro FJ, Cabas I, Martinez-Vicente I, Armistead J, Hatzold J, Lopez MA, Martinez MT, Corbalan VR, et al. 2021. NAMPT-derived NAD + fuels PARP1 to promote skin inflammation through parthanatos cell death. PLoS Biol. 19(11):e3001455.
  • Meyer-Ficca ML, Zwerdling AE, Swanson CA, Tucker AG, Lopez SA, Wandersee MK, Warner GM, Thompson KL, Chini CCS, Chen H, et al. 2022. Low NAD(+) levels are associated with a decline of spermatogenesis in transgenic ANDY and aging mice. Front Endocrinol13:896356.
  • Peck B, Chen CY, Ho KK, Di Fruscia P, Myatt SS, Coombes RC, Fuchter MJ, Hsiao CD, Lam EW. 2010. SIRT inhibitors induce cell death and p53 acetylation through targeting both SIRT1 and SIRT2. Mol Cancer Ther. 9(4):844–855.
  • Pizzol D, Foresta C, Garolla A, Demurtas J, Trott M, Bertoldo A, Smith L. 2021. Pollutants and sperm quality: a systematic review and meta-analysis. Environ Sci Pollut Res Int. 28(4):4095–4103.
  • Renu K, Madhyastha H, Madhyastha R, Maruyama M, Vinayagam S, Valsala Gopalakrishnan A. 2018. Review on molecular and biochemical insights of arsenic-mediated male reproductive toxicity. Life Sci. 212:37–58.
  • Singh CK, Chhabra G, Ndiaye MA, Garcia-Peterson LM, Mack NJ, Ahmad N. 2018. The role of sirtuins in antioxidant and redox signaling. Antioxid Redox Signal. 28(8):643–661.
  • Tatone C, Di Emidio G, Barbonetti A, Carta G, Luciano AM, Falone S, Amicarelli F. 2018. Sirtuins in gamete biology and reproductive physiology: emerging roles and therapeutic potential in female and male infertility. Hum Reprod Update. 24(3):267–289.
  • Vaziri H, Dessain SK, Ng Eaton E, Imai SI, Frye RA, Pandita TK, Guarente L, Weinberg RA. 2001. hSIR2(SIRT1) functions as an NAD-dependent p53 deacetylase. Cell. 107(2):149–159.
  • Wang M, Hou S, Lu X, Li J, Li R, Yan X. 2021. Interleukin-37 inhibits inflammation activation and disease severity of PM2.5-induced airway hyperresponsiveness. Ecotoxicol Environ Saf. 227:112890.
  • Wang C, Liu X, Shu Z, Yin J, Xiao M, Ai Y, Zhao P, Luo Z, Liu B. 2022. Exposure to automobile exhaust-derived PM2.5 induces spermatogenesis dysfunction by damaging UPR(mt) of prepubertal rats. Ecotoxicol Environ Saf. 245:114087.
  • Wang Y, Zhong Y, Liao J, Wang G. 2021. PM2.5-related cell death patterns. Int J Med Sci. 18(4):1024–1029.
  • Yang Q, Cong L, Wang Y, Luo X, Li H, Wang H, Zhu J, Dai S, Jin H, Yao G, et al. 2020. Increasing ovarian NAD(+) levels improve mitochondrial functions and reverse ovarian aging. Free Radic Biol Med. 156:1–10.
  • Yang Y, Feng Y, Huang H, Cui L, Li F. 2021. PM2.5 exposure induces reproductive injury through IRE1/JNK/autophagy signaling in male rats. Ecotoxicol Environ Saf. 211:111924.
  • Yang Y, Liu Y, Wang Y, Chao Y, Zhang J, Jia Y, Tie J, Hu D. 2022. Regulation of SIRT1 and Its Roles in Inflammation. Front Immunol. 13:831168.
  • Yoshino J, Baur JA, Imai SI. 2018. NAD(+) intermediates: the biology and therapeutic potential of NMN and NR. Cell Metab. 27(3):513–528.
  • Yu SW, Andrabi SA, Wang H, Kim NS, Poirier GG, Dawson TM, Dawson VL. 2006. Apoptosis-inducing factor mediates poly(ADP-ribose) (PAR) polymer-induced cell death. Proc Natl Acad Sci U S A. 103(48):18314–18319.
  • Yu SW, Wang H, Poitras MF, Coombs C, Bowers WJ, Federoff HJ, Poirier GG, Dawson TM, Dawson VL. 2002. Mediation of poly(ADP-ribose) polymerase-1-dependent cell death by apoptosis-inducing factor. Science. 297(5579):259–263.
  • Yue W, Tong L, Liu X, Weng X, Chen X, Wang D, Dudley SC, Weir EK, Ding W, Lu Z, et al. 2019. Short term Pm2.5 exposure caused a robust lung inflammation, vascular remodeling, and exacerbated transition from left ventricular failure to right ventricular hypertrophy. Redox Biol. 22:101161.
  • Zapata-Perez R, Wanders RJA, van Karnebeek CDM, Houtkooper RH. 2021. NAD(+) homeostasis in human health and disease. EMBO Mol Med. 13(7):e13943.
  • Zhao C, Wang Y, Su Z, Pu W, Niu M, Song S, Wei L, Ding Y, Xu L, Tian M, et al. 2020. Respiratory exposure to PM2.5 soluble extract disrupts mucosal barrier function and promotes the development of experimental asthma. Sci Total Environ. 730:139145.
  • Zhao Y, Zhu Q, Lin J, Cai J. 2022. Association of exposure to particulate matter air pollution with semen quality among men in China. JAMA Netw Open. 5(2):e2148684.
  • Zhou L, Su X, Li B, Chu C, Sun H, Zhang N, Han B, Li C, Zou B, Niu Y, et al. 2019. PM2.5 exposure impairs sperm quality through testicular damage dependent on NALP3 inflammasome and miR-183/96/182 cluster targeting FOXO1 in mouse. Ecotoxicol Environ Saf. 169:551–563.
  • Zhou S, Xi Y, Chen Y, Zhang Z, Wu C, Yan W, Luo A, Wu T, Zhang J, Wu M, et al. 2020. Ovarian dysfunction induced by chronic whole-body PM2.5 exposure. Small. 16(33):e2000845.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.