27
Views
6
CrossRef citations to date
0
Altmetric
Research Article

ALTERATION IN AROMATIC HYDROXYLATION AND LIPID OXIDATION STATUS IN THE LUNGS OF RATS EXPOSED TO OZONE

, , , &
Pages 195-210 | Received 09 Mar 2001, Accepted 24 Dec 2001, Published online: 30 Sep 2008

REFERENCES

  • Burnett, R. T., Smith-Doiron, M., Steib, D., Cakmak, S., and Brook, J. R. 1999. Effects of particulate and gaseous air pollution on cardio-respiratory hospitalization. Arch. Environ. Health 54: 130–139.
  • Mustafa, M. G. 1990. Biochemical basis of ozone toxicity. Free Rad. Biol. Med. 9: 245–265.
  • Arito, H., Uchiyama, I., Arakawa, H., and Yokoyama, E. 1990. Ozone-induced bradycardia and arrhythmia and their relation to sleep-wakefulness in rats. Toxicol. Lett. 52: 169–178.
  • Koppenol, W. H. 1982. The reduction potential of the couple ozone and the ozonide radical anion. FEBS Lett. 140: 169–172.
  • Pryor, A. W., and Church, D. F. 1991. Aldehydes, hydrogen peroxide, and organic radicals as mediators of ozone toxicity. Free Rad. Biol. Med. 11: 41–46.
  • Kennedy, C. H., Hatch, G. E., Slade, R., and Mason, R. P. 1992. Application of the EPR spin trapping technique to the detection of radicals produced in vivo during inhalation exposure of rats to ozone. Toxicol. Appl. Pharmacol. 114: 41–46.
  • Pryor, A. W., Das, B., and Church, D. F. 1991. The ozonation of unsaturated fattyacids: aldehydes and hydrogen peroxide as products and possible mediators of ozone toxicity. Chem. Res. Toxicol. 4: 341–348.
  • Freeman, B. A., and Crapo, J. D. 1981. Hyperoxia increases oxygen radical production in rat lungs and lung mitochondria. J. Biol. Chem. 256: 10986–10992.
  • Kasai, H., Crain, P. F., Kuchino, Y., Nishimura, A., Ootsuyama, A., and Tanooka, H. 1986. Formation of 8-hydroxyguanine moiety in cellular DNA by agents producing oxygen radicals and evidence for its repair. Carcinogenesis 7: 1849–1851.
  • Burdon, R. H. 1995. Superoxide and hydrogen peroxide in relation to mammalian cell proliferation. Free Rad. Biol. Med. 18: 775–794.
  • Liu, L., Kumarathasan, P., Guénette, J., and Vincent, R. 1996. Hydroxylation of salicylate in lungs of Fischer 344 rats: effects of aging and ozone exposure. Am. J. Physiol. 271: L995–L1003.
  • Vincent, R., Janzen, E. G., Chen, G., Kumarathasan, P., Haire, D. L., Guénette, J., Chen, J. Z., and Bray, T. M. 1996. Spin trapping study in the lungs and liver of F344 rats after exposure to ozone. Free Rad. Res. 25: 475–488.
  • Kumarathasan, P., Vincent, R., Goegan, P., Potvin, M., and Guénette, J. 2001. Hydroxyl radical adduct of 5-aminosalicylic acid: a potential marker of ozone-induced oxidative stress. Biochem. Cell Biol. 79: 1–10.
  • Leikauf, G. D., Zhao, Q., Zhou, S., and Santrock, J. 1995. Activation of eicosanoid metabolism in human airway epithelial cells by ozonolysis products of membrane fatty acids. Res. Rep. Health Eff. Inst. Sep. 71: 1–15; discussion 19–26.
  • Leikauf, G. D., Zhao, Q., Zhou, S., and Santrock, J. 1993. Ozonolysis products of membrane fattyacids activate eicosanoid metabolism in human airway epithelial cells. Am. J. Respir. Cell. Mol. Biol. 9: 594–602.
  • Samuelson, B. 1983. Leukotrienes: mediators of immediate hypersensitivity reactions and inflammation. Science 220: 568–575.
  • Pendino, K. J., Meidhof, T. M., Heck D. E., Laskin, J. D., and Laskin, D. L. 1995. Inhibition of macrophages with gadolinium chloride abrogates ozone-induced pulmonary injury and inflammatory mediator production. Am. J. Respir. Cell. Mol. Biol. 13: 125–132.
  • Esterline, R. L., Bassett, D. J. P., and Trush, M. A. 1989. Characterization of the oxidant generation by inflammatory cells lavaged from the rat lungs following acute exposure to ozone. Toxicol. Appl. Pharmacol. 99: 229–239.
  • Becker, S., Madden, M. C., Newman, S. L., Devlin, R. B., and Koren, H. S. 1991. Modulation of human alveolar macrophage properties by ozone exposure in vitro. Toxicol. Appl. Pharmacol. 110: 403–415.
  • Dew, M. J., Harries, A. D., Evans, N., Evans, B. K., and Rhodes, J. 1983. Maintenance of remission in ulcerative colitis with 5-amino salicylic acid in high doses by mouth. Br. J. Med. 287: 23–24.
  • Allgayer, H., Hoffer, P., Schmidt, M., Bohne, P., Kruis, W., and Gugler, R. 1992. Superoxide, hydroxyl and fattyacid radical scavenging by amino salicylates: direct evaluation with electron spin resonance spectroscopy. Biochem. Pharmacol. 43: 259–262.
  • Stenson, W. F., and Lobos, E. 1982. Sulfasalazine inhibits the synthesis of chemotactic lipids by neutrophils. J. Clin. Invest. 69: 494–497.
  • Bitton, A., Peppercorn, M. A., Hanrahan, J. P., and Upton, M. P. 1996. Mesalamine-induced lung toxicity. Am. J. Gastroenterol. 91: 1039–1040.
  • Guenette, J., Hayes, S., and Vincent, R. 1997. Stable gaseous atmospheres for nose-only inhalation using mass flow controllers. Toxicol. Meth. 7: 77–89.
  • Vincent, R., Bjarnason, S. G., Adamson, I. Y. R., Hedgecock, C., Guenette, J., Potvin, M., Kumarathasan, P., Goegan, P., and Bouthillier, L. 1997. Acute pulmonary toxicity of urban particulate matter and ozone. Am. J. Pathol. 151: 1563–1570.
  • Hatch, G. E., Slade, R., Harris, L. P., McDonnel, W. F., Devlin, R. B., Koren, H. S., Costa, D. L., and McKee, J. 1994. Ozone dose and effect in humans and rats: a comparison using oxygen-18 labeling and bronchoalveolar lavage. Am. Rev. Respir. Cell. Mol. Biol. 150: 676–683.
  • Vincent, R., Vu, D., Hatch, G., Poon, R., Dreher, K., Guénette, J., Bjarnason, S., Potvin, M., Norwood, J., and McMullen, E. 1996. Sensitivity of lungs of aging Fischer 344 rats to ozone: assesment by bronchoalveolar lavage. Am. J. Physiol. 271: , Lung Cell Mol. Physiol. 15: L555–L565.
  • Vincent, R., and Nadeau, D. 1983. A micromethod for the quantitation of cellular proteins in Percoll with the Coomassie brilliant blue dye-binding assay. Anal. Biochem. 135: 355–362.
  • Bhalla, D. K. 1994. Alteration of ozone-induced airway permeability by oxygen metabolites and antioxidants. Toxicol. Lett. 73: 91–101.
  • van Deventer, S. J., and Tytgat, G. N. 1998. Drug treatment of Crohn's disease. Ned. Tijdschr. Geneeskd. 142: 1191–1195.
  • Ishii, Y., Hashimoto, K., Hirano, K., Morishima, Y., Mochizuki, M., Masuyama, K., Nomura, A., Sakamoto, T., Uchida, Y., Sagai, M., and Sekizawa, K. 2000. Ebselen decreases ozone-induced pulmonary inflammation in rats. Lung 178: 225–234.
  • Esterline, R. L., Bassett, D. J. P., and Trush, M. A. 1989. Characterization of the oxidant generation by inflammatory cells lavaged from rat lungs following acute exposure to ozone. Toxicol. Appl. Pharmacol. 99: 229–239.
  • Hotchkiss, J. A., Harkema, J. R., Sun, J. D., and Henderson, R. F. 1989. Comparison of acute ozone-induced nasal and pulmonary inflammatory responses in rats. Toxicol. Appl. Pharmacol. 98: 289–302.
  • Pryor, W. A., Bermudez, E., Cueto, R., and Squadrito, G. L. 1996. Detection of aldehydes in bronchoalveolar lavage of rats exposed to ozone. Fundam. Appl. Toxicol. 34: 148–156.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.