COX-2 dependent regulation of mechanotransduction in human breast cancer cells

References

• DeSantis C, Ma J, Bryan L, Jemal A. Breast cancer statistics, 2013. CA Cancer J Clin 2014; 64:52-62; PMID:24114568.
   PubMed Web of Science ®Google Scholar
• Jemal A, Ward E, Thun MJ. Recent trends in breast cancer incidence rates by age and tumor characteristics among US women. Breast Cancer Res 2007; 9:R28; PMID:17477859; http://dx.doi.org/10.1186/bcr1672.
   PubMed Web of Science ®Google Scholar
• McPherson K, Steel CM, Dixon JM. ABC of breast diseases. Breast cancer-epidemiology, risk factors, and genetics. Bmj 2000; 321:624-8; PMID:10977847; http://dx.doi.org/10.1136/bmj.321.7261.624.
   PubMed Web of Science ®Google Scholar
• Chambers AF, Groom AC, MacDonald IC. Dissemination and growth of cancer cells in metastatic sites. Nat Rev Cancer 2002; 2:563-72; PMID:12154349; http://dx.doi.org/10.1038/nrc865.
   PubMed Web of Science ®Google Scholar
• Fidler IJ. The pathogenesis of cancer metastasis: the 'seed and soil' hypothesis revisited. Nat Rev Cancer 2003; 3:453-8; PMID:12778135; http://dx.doi.org/10.1038/nrc1098.
   PubMed Web of Science ®Google Scholar
• Quail DF, Joyce JA. Microenvironmental regulation of tumor progression and metastasis. Nature Med 2013; 19:1423-37; PMID:24202395; http://dx.doi.org/10.1038/nm.3394.
   PubMed Web of Science ®Google Scholar
• Balkwill F, Mantovani A. Inflammation and cancer: back to Virchow? Lancet 2001; 357:539-45; PMID:11229684; http://dx.doi.org/10.1016/S0140-6736(00)04046-0.
   PubMed Web of Science ®Google Scholar
• Hagemann T, Balkwill F, Lawrence T. Inflammation and cancer: a double-edged sword. Cancer Cell 2007; 12:300-1; PMID:17936555; http://dx.doi.org/10.1016/j.ccr.2007.10.005.
   PubMed Web of Science ®Google Scholar
• Garavito RM, DeWitt DL. The cyclooxygenase isoforms: structural insights into the conversion of arachidonic acid to prostaglandins. Biochim Biophys Acta 1999; 1441:278-87; PMID:10570255; http://dx.doi.org/10.1016/S1388-1981(99)00147-X.
   PubMed Web of Science ®Google Scholar
• Achiwa H, Yatabe Y, Hida T, Kuroishi T, Kozaki K, Nakamura S, Ogawa M, Sugiura T, Mitsudomi T, Takahashi T. Prognostic significance of elevated cyclooxygenase 2 expression in primary, resected lung adenocarcinomas. Clin Cancer Res 1999; 5:1001-5; PMID:10353732.
   PubMed Web of Science ®Google Scholar
• Buskens CJ, Van Rees BP, Sivula A, Reitsma JB, Haglund C, Bosma PJ, Offerhaus GJ, Van Lanschot JJ, Ristimaki A. Prognostic significance of elevated cyclooxygenase 2 expression in patients with adenocarcinoma of the esophagus. Gastroenterology 2002; 122:1800-7; PMID:12055587; http://dx.doi.org/10.1053/gast.2002.33580.
   PubMed Web of Science ®Google Scholar
• Gupta RA, Dubois RN. Colorectal cancer prevention and treatment by inhibition of cyclooxygenase-2. Nat Rev Cancer 2001; 1:11-21; PMID:11900248; http://dx.doi.org/10.1038/35094017.
   PubMed Web of Science ®Google Scholar
• Ristimaki A, Sivula A, Lundin J, Lundin M, Salminen T, Haglund C, Joensuu H, Isola J. Prognostic significance of elevated cyclooxygenase-2 expression in breast cancer. Cancer Res 2002; 62:632-5; PMID:11830510.
   PubMed Web of Science ®Google Scholar
• Wang D, DuBois RN. Cyclooxygenase 2-derived prostaglandin E2 regulates the angiogenic switch. Proc Natl Acad Sci U S A 2004; 101:415-6; PMID:14707264; http://dx.doi.org/10.1073/pnas.0307640100.
   PubMed Web of Science ®Google Scholar
• Wang D, Dubois RN. Eicosanoids and cancer. Nat Rev Cancer 2010; 10:181-93; PMID:20168319; http://dx.doi.org/10.1038/nrc2809.
   PubMed Web of Science ®Google Scholar
• Chang SH, Liu CH, Conway R, Han DK, Nithipatikom K, Trifan OC, Lane TF, Hla T. Role of prostaglandin E2-dependent angiogenic switch in cyclooxygenase 2-induced breast cancer progression. Proc Natl Acad Sci U S A 2004; 101:591-6; PMID:14688410; http://dx.doi.org/10.1073/pnas.2535911100.
   PubMed Web of Science ®Google Scholar
• Shah T, Stasinopoulos I, Wildes F, Kakkad S, Artemov D, Bhujwalla ZM. Noninvasive imaging identifies new roles for cyclooxygenase-2 in choline and lipid metabolism of human breast cancer cells. NMR Biomed 2012; 25:746-54; PMID:21953546; http://dx.doi.org/10.1002/nbm.1789.
   PubMed Web of Science ®Google Scholar
• Stasinopoulos I, O'Brien DR, Wildes F, Glunde K, Bhujwalla ZM. Silencing of cyclooxygenase-2 inhibits metastasis and delays tumor onset of poorly differentiated metastatic breast cancer cells. Mol Cancer Res 2007; 5:435-42; PMID:17510310; http://dx.doi.org/10.1158/1541-7786.MCR-07-0010.
   PubMed Web of Science ®Google Scholar
• Keller PJ, Lin AF, Arendt LM, Klebba I, Jones AD, Rudnick JA, DiMeo TA, Gilmore H, Jefferson DM, Graham RA, et al. Mapping the cellular and molecular heterogeneity of normal and malignant breast tissues and cultured cell lines. Breast Cancer Res 2010; 12:R87; PMID:20964822; http://dx.doi.org/10.1186/bcr2755.
   PubMed Web of Science ®Google Scholar
• An SS, Kim J, Ahn K, Trepat X, Drake KJ, Kumar S, Ling G, Purington C, Rangasamy T, Kensler TW, et al. Cell stiffness, contractile stress and the role of extracellular matrix. Biochem Biophys Res Commun 2009; 382:697-703; PMID:19327344; http://dx.doi.org/10.1016/j.bbrc.2009.03.118.
   PubMed Web of Science ®Google Scholar
• Garzon-Muvdi T, Schiapparelli P, ap Rhys C, Guerrero-Cazares H, Smith C, Kim DH, Kone L, Farber H, Lee DY, An SS, et al. Regulation of brain tumor dispersal by NKCC1 through a novel role in focal adhesion regulation. PLoS Biol 2012; 10:e1001320; PMID:22570591; http://dx.doi.org/10.1371/journal.pbio.1001320.
   PubMedGoogle Scholar
• Wang N, Tolic-Norrelykke IM, Chen J, Mijailovich SM, Butler JP, Fredberg JJ, Stamenovic D. Cell prestress. I. Stiffness and prestress are closely associated in adherent contractile cells. Am J Physiol Cell Physiol 2002; 282:C606-16; PMID:11832346; http://dx.doi.org/10.1152/ajpcell.00269.2001.
   PubMed Web of Science ®Google Scholar
• Samani A, Zubovits J, Plewes D. Elastic moduli of normal and pathological human breast tissues: an inversion-technique-based investigation of 169 samples. Phys Med Biol 2007; 52:1565-76; PMID:17327649; http://dx.doi.org/10.1088/0031-9155/52/6/002.
   PubMed Web of Science ®Google Scholar
• Hoffmeyer MR, Wall KM, Dharmawardhane SF. In vitro analysis of the invasive phenotype of SUM 149, an inflammatory breast cancer cell line. Cancer Cell Int 2005; 5:11; PMID:15857504; http://dx.doi.org/10.1186/1475-2867-5-11.
   PubMed Web of Science ®Google Scholar
• Butler JP, Tolic-Norrelykke IM, Fabry B, Fredberg JJ. Traction fields, moments, and strain energy that cells exert on their surroundings. Am J Physiol Cell Physiol 2002; 282:C595-605; PMID:11832345; http://dx.doi.org/10.1152/ajpcell.00270.2001.
   PubMed Web of Science ®Google Scholar
• Singh B, Berry JA, Shoher A, Ramakrishnan V, Lucci A. COX-2 overexpression increases motility and invasion of breast cancer cells. Int J Oncol 2005; 26:1393-9; PMID:15809733.
   PubMed Web of Science ®Google Scholar
• Bursac P, Fabry B, Trepat X, Lenormand G, Butler JP, Wang N, Fredberg JJ, An SS. Cytoskeleton dynamics: fluctuations within the network. Biochem Biophys Res Commun 2007; 355:324-30; PMID:17303084; http://dx.doi.org/10.1016/j.bbrc.2007.01.191.
   PubMed Web of Science ®Google Scholar
• Bursac P, Lenormand G, Fabry B, Oliver M, Weitz DA, Viasnoff V, Butler JP, Fredberg JJ. Cytoskeletal remodelling and slow dynamics in the living cell. Nat Mater 2005; 4:557-61; PMID:15937489; http://dx.doi.org/10.1038/nmat1404.
   PubMed Web of Science ®Google Scholar
• Angelini TE, Hannezo E, Trepat X, Fredberg JJ, Weitz DA. Cell migration driven by cooperative substrate deformation patterns. Phys Rev Lett 2010; 104:168104; PMID:20482085; http://dx.doi.org/10.1103/PhysRevLett.104.168104.
   PubMed Web of Science ®Google Scholar
• Abrahao AC, Castilho RM, Squarize CH, Molinolo AA, dos Santos-Pinto D, Jr., Gutkind JS. A role for COX2-derived PGE2 and PGE2-receptor subtypes in head and neck squamous carcinoma cell proliferation. Oral Oncol 2010; 46:880-7; PMID:20951077; http://dx.doi.org/10.1016/j.oraloncology.2010.09.005.
   PubMed Web of Science ®Google Scholar
• Trepat X, Deng L, An SS, Navajas D, Tschumperlin DJ, Gerthoffer WT, Butler JP, Fredberg JJ. Universal physical responses to stretch in the living cell. Nature 2007; 447:592-595; PMID:17538621; http://dx.doi.org/10.1038/nature05824.
   PubMed Web of Science ®Google Scholar
• Deshpande DA, Wang WCH, McIlmoyle EL, Robinett KS, Schillinger RM, An SS, Sham JSK, Liggett SB. Bitter taste receptors on airway smooth muscle bronchodilate by localized calcium signaling and reverse obstruction. Nat Med 2010; 16:1299-1304; PMID:20972434; http://dx.doi.org/10.1038/nm.2237.
   PubMed Web of Science ®Google Scholar
• Kim JJ, Yin B, Christudass CS, Terada N, Rajagopalan K, Fabry B, Lee DY, Shiraishi T, Getzenberg RH, Veltri RW, et al. Acquisition of paclitaxel resistance is associated with a more aggressive and invasive phenotype in prostate cancer. J Cell Biochem 2013; 114:1286-1293; PMID:23192682; http://dx.doi.org/10.1002/jcb.24464.
   PubMed Web of Science ®Google Scholar
• Lawrence RA, Jones RL. Investigation of the prostaglandin E (EP-) receptor subtype mediating relaxation of the rabbit jugular vein. Br J Pharmacol 1992; 105:817-824; PMID:1324050; http://dx.doi.org/10.1111/j.1476-5381.1992.tb09063.x.
   PubMed Web of Science ®Google Scholar
• Hu M, Peluffo G, Chen H, Gelman R, Schnitt S, Polyak K. Role of COX-2 in epithelial-stromal cell interactions and progression of ductal carcinoma in situ of the breast. Proc Natl Acad Sci U S A 2009; 106:3372-7; PMID:19218449; http://dx.doi.org/10.1073/pnas.0813306106.
   PubMed Web of Science ®Google Scholar
• Fulton AM. The role of eicosanoids in tumor metastasis. Prostaglandins Leukot Essent Fatty Acids 1988; 34:229-37; PMID:3065787.
   PubMed Web of Science ®Google Scholar
• Liu JF, Fong YC, Chang CS, Huang CY, Chen HT, Yang WH, Hsu CJ, Jeng LB, Chen CY, Tang CH. Cyclooxygenase-2 enhances alpha2beta1 integrin expression and cell migration via EP1 dependent signaling pathway in human chondrosarcoma cells. Mol Cancer; 9:43; PMID:20178602; http://dx.doi.org/10.1186/1476-4598-9-43.
   PubMed Web of Science ®Google Scholar
• Menter DG, Schilsky RL, DuBois RN. Cyclooxygenase-2 and cancer treatment: understanding the risk should be worth the reward. Clin Cancer Res; 16:1384-90; PMID:20179228; http://dx.doi.org/10.1158/1078-0432.CCR-09-0788.
   PubMed Web of Science ®Google Scholar
• Smith WL, DeWitt DL, Garavito RM. Cyclooxygenases: structural, cellular, and molecular biology. Annu Rev Biochem 2000; 69:145-82; PMID:10966456; http://dx.doi.org/10.1146/annurev.biochem.69.1.145.
   PubMed Web of Science ®Google Scholar
• Howe LR. Inflammation and breast cancer. Cyclooxygenase/prostaglandin signaling and breast cancer. Breast Cancer Res 2007; 9:210; PMID:17640394; http://dx.doi.org/10.1186/bcr1678.
   PubMed Web of Science ®Google Scholar
• Singh-Ranger G, Salhab M, Mokbel K. The role of cyclooxygenase-2 in breast cancer: review. Breast Cancer Res Treat 2008; 109:189-98; PMID:17624587; http://dx.doi.org/10.1007/s10549-007-9641-5.
   PubMed Web of Science ®Google Scholar
• Koch TM, Munster S, Bonakdar N, Butler JP, Fabry B. 3D Traction forces in cancer cell invasion. PloS one 2012; 7:e33476; PMID:22479403; http://dx.doi.org/10.1371/journal.pone.0033476.
   PubMedGoogle Scholar
• Kraning-Rush CM, Califano JP, Reinhart-King CA. Cellular traction stresses increase with increasing metastatic potential. PloS one 2012; 7:e32572; PMID:22389710; http://dx.doi.org/10.1371/journal.pone.0032572.
   PubMed Web of Science ®Google Scholar
• Grosch S, Maier TJ, Schiffmann S, Geisslinger G. Cyclooxygenase-2 (COX-2)-independent anticarcinogenic effects of selective COX-2 inhibitors. J Natl Cancer Inst. 2006; 98:736-747; PMID:16757698; http://dx.doi.org/10.1093/jnci/djj206.
   PubMed Web of Science ®Google Scholar
• Zhang W, Nandakumar N, Shi Y, Manzano M, Smith A, Graham G, Gupta S, Vietsch EE, Laughlin SZ, Wadhwa M, et al. Downstream of mutant KRAS, the transcription regulator YAP is essential for neoplastic progression to pancreatic ductal adenocarcinoma. Sci Signal 2014; 7:ra42; PMID:24803537.
   PubMed Web of Science ®Google Scholar
• Provenzano PP, Inman DR, Eliceiri KW, Knittel JG, Yan L, Rueden CT, White JG, Keely PJ. Collagen density promotes mammary tumor initiation and progression. BMC Med 2008; 6:11; PMID:18442412; http://dx.doi.org/10.1186/1741-7015-6-11.
   PubMed Web of Science ®Google Scholar
• Kakkad SM, Solaiyappan M, Argani P, Sukumar S, Jacobs LK, Leibfritz D, Bhujwalla ZM, Glunde K. Collagen I fiber density increases in lymph node positive breast cancers: pilot study. J Biomed Optics 2012; 17:116017; PMID:23117811; http://dx.doi.org/10.1117/1.JBO.17.11.116017.
   PubMed Web of Science ®Google Scholar
• Ulrich TA, de Juan Pardo EM, Kumar S. The mechanical rigidity of the extracellular matrix regulates the structure, motility, and proliferation of glioma cells. Cancer Res 2009; 69:4167-74; PMID:19435897; http://dx.doi.org/10.1158/0008-5472.CAN-08-4859.
   PubMed Web of Science ®Google Scholar
• Pathak A, Kumar S. Independent regulation of tumor cell migration by matrix stiffness and confinement. Proc Natl Acad Sci U S A 2012; 109:10334-9; PMID:22689955; http://dx.doi.org/10.1073/pnas.1118073109.
   PubMed Web of Science ®Google Scholar
• Wang YL, Pelham RJ, Jr. Preparation of a flexible, porous polyacrylamide substrate for mechanical studies of cultured cells. Methods Enzymol 1998; 298:489-96; PMID:9751904; http://dx.doi.org/10.1016/S0076-6879(98)98041-7.
   PubMed Web of Science ®Google Scholar
• Fabry B, Maksym GN, Butler JP, Glogauer M, Navajas D, Fredberg JJ. Scaling the microrhelolgy of living cells. Phys Rev Lett 2011; 87:148102; http://dx.doi.org/10.1103/PhysRevLett.87.148102.
   Web of Science ®Google Scholar
• Dai ZJ, Ma XB, Kang HF, Gao J, Min WL, Guan HT, Diao Y, Lu WF, Wang XJ. Antitumor activity of the selective cyclooxygenase-2 inhibitor, celecoxib, on breast cancer in vitro and in vivo. Cancer Cell Int 2012; 12:53-61; PMID:23249419; http://dx.doi.org/10.1186/1475-2867-12-53.
   PubMed Web of Science ®Google Scholar