p8 attenuates the apoptosis induced by dihydroartemisinin in cancer cells through promoting autophagy

References

• Krishna S, Bustamante L, Haynes RK, Staines HM. Artemisinins: their growing importance in medicine. Trends Pharmacol Sci 2008; 29:520-7; PMID: 18752857; http://dx.doi.org/10.1016/j.tips.2008.07.004
   PubMed Web of Science ®Google Scholar
• Singh NP, Lai H. Selective toxicity of dihydroartemisinin and holotransferrin toward human breast cancer cells. Life Sci 2001; 70:49-56; PMID: 11764006; http://dx.doi.org/10.1016/S0024-3205(01)01372-8
   PubMed Web of Science ®Google Scholar
• Chen T, Li MA, Zhang RW, Wang H. Dihydroartemisinin induces apoptosis and sensitizes human ovarian cancer cells to carboplatin therapy. J Cell Mol Med 2009; 13:1358-70; PMID: 18466355; http://dx.doi.org/10.1111/j.1582-4934.2008.00360.x
   PubMed Web of Science ®Google Scholar
• Hu CJ, Zhou L, Cai Y. Dihydroartemisinin induces apoptosis of cervical cancer cells via upregulation of RKIP and downregulation of bcl-2. Cancer Biol Ther 2014; 15:279-88; PMID: 24335512; http://dx.doi.org/10.4161/cbt.27223
   PubMed Web of Science ®Google Scholar
• Lu JJ, Chen SM, Zhang XW, Ding J, Meng LH. The anti-cancer activity of dihydroartemisinin is associated with induction of iron-dependent endoplasmic reticulum stress in colorectal carcinoma HCT116 cells. Invest New Drugs 2011; 29:1276-83; PMID: 20607588; http://dx.doi.org/10.1007/s10637-010-9481-8
   PubMed Web of Science ®Google Scholar
• Mercer AE, Maggs JL, Sun XM, Cohen GM, Chadwick J, O'Neill PM, Park BK. Evidence for the involvement of carbon-centered radicals in the induction of apoptotic cell death by artemisinin compounds. J Biol Chem 2007; 282:9372-82; PMID: 17227762; http://dx.doi.org/10.1074/jbc.M610375200
   PubMed Web of Science ®Google Scholar
• Shterman N, Kupfer B, Moroz C. Comparison of transferrin receptors, iron content and isoferritin profile in normal and malignant human breast cell-lines. Pathobiology 1991; 59:19-25; PMID: 2043266; http://dx.doi.org/10.1159/000163611
   PubMed Web of Science ®Google Scholar
• Lai H, Singh NP. Selective cancer cell cytotoxicity from exposure to dihydroartemisinin and holotransferrin. Cancer Lett 1995; 91:41-6; PMID: 7750093; http://dx.doi.org/10.1016/0304-3835(94)03716-V
   PubMed Web of Science ®Google Scholar
• Mallo GV, Fiedler F, Calvo EL, Ortiz EM, Vasseur S, Keim V, Morisset J, Iovanna JL. Cloning and expression of the rat p8 cDNA, a new gene activated in pancreas during the acute phase of pancreatitis, pancreatic development, and regeneration, and which promotes cellular growth. J Biol Chem 1997; 272:32360-9; PMID: 9405444; http://dx.doi.org/10.1074/jbc.272.51.32360
   PubMed Web of Science ®Google Scholar
• Vasseur S, Folch-Puy E, Hlouschek V, Garcia S, Fiedler F, Lerch MM, Dagorn JC, Closa D, Iovanna JL. p8 improves pancreatic response to acute pancreatitis by enhancing the expression of the anti-inflammatory protein pancreatitis-associated protein I. J Biol Chem 2004; 279:7199-207; PMID: 14660681; http://dx.doi.org/10.1074/jbc.M309152200
   PubMed Web of Science ®Google Scholar
• Brannon KM, Million Passe CM, White CR, Bade NA, King MW, Quirk CC. Expression of the high mobility group A family member p8 is essential to maintaining tumorigenic potential by promoting cell cycle dysregulation in LbetaT2 cells. Cancer Lett 2007; 254:146-55; PMID: 17451874; http://dx.doi.org/10.1016/j.canlet.2007.03.011
   PubMed Web of Science ®Google Scholar
• Salazar M, Carracedo A, Salanueva IJ, Hernandez-Tiedra S, Lorente M, Egia A, Vázquez P, Blázquez C, Torres S, García S, et al. Cannabinoid action induces autophagy-mediated cell death through stimulation of ER stress in human glioma cells. J Clin Invest 2009; 119:1359-72; PMID: 19425170; http://dx.doi.org/10.1172/JCI37948
   PubMed Web of Science ®Google Scholar
• Hamidi T, Algul H, Cano CE, Sandi MJ, Molejon MI, Riemann M, Calvo EL, Lomberk G, Dagorn JC, Weih F, et al. Nuclear protein 1 promotes pancreatic cancer development and protects cells from stress by inhibiting apoptosis. J Clin Invest 2012; 122:2092-103; PMID: 22565310; http://dx.doi.org/10.1172/JCI60144
   PubMed Web of Science ®Google Scholar
• Giroux V, Malicet C, Barthet M, Gironella M, Archange C, Dagorn JC, Vasseur S, Iovanna JL. p8 is a new target of gemcitabine in pancreatic cancer cells. Clin Cancer Res 2006; 12:235-41; PMID: 16397047; http://dx.doi.org/10.1158/1078-0432.CCR-05-1700
   PubMed Web of Science ®Google Scholar
• Davies ML, Parr C, Sanders AJ, Fodstad O, Jiang WG. The transcript expression and protein distribution pattern in human colorectal carcinoma reveal a pivotal role of COM-1/p8 as a tumour suppressor. Cancer Genomics Proteomics 2010; 7:75-80; PMID: 20335521
   PubMedGoogle Scholar
• Ree AH, Bratland A, Kroes RA, Aasheim HC, Florenes VA, Moskal JR, Fodstad O, Bruland OS, Maelandsmo GM. Clinical and cell line specific expression profiles of a human gene identified in experimental central nervous system metastases. Anticancer Res 2002; 22:1949-57; PMID: 12174869
   PubMed Web of Science ®Google Scholar
• Vasseur S, Hoffmeister A, Garcia-Montero A, Mallo GV, Feil R, Kuhbandner S, Dagorn JC, Iovanna JL. p8-deficient fibroblasts grow more rapidly and are more resistant to adriamycin-induced apoptosis. Oncogene 2002; 21:1685-94; PMID: 11896600; http://dx.doi.org/10.1038/sj.onc.1205222
   PubMed Web of Science ®Google Scholar
• Cano CE, Hamidi T, Sandi MJ, Iovanna JL. Nupr1: the Swiss-knife of cancer. J Cell Physiol 2011; 226:1439-43; PMID: 20658514; http://dx.doi.org/10.1002/jcp.22324
   PubMed Web of Science ®Google Scholar
• Carracedo A, Lorente M, Egia A, Blazquez C, Garcia S, Giroux V, Malicet C, Villuendas R, Gironella M, González-Feria L, et al. The stress-regulated protein p8 mediates cannabinoid-induced apoptosis of tumor cells. Cancer Cell 2006; 9:301-12; PMID: 16616335; http://dx.doi.org/10.1016/j.ccr.2006.03.005
   PubMed Web of Science ®Google Scholar
• Kim I, Xu W, Reed JC. Cell death and endoplasmic reticulum stress: disease relevance and therapeutic opportunities. Nat Rev Drug Discov 2008; 7:1013-30; PMID: 19043451; http://dx.doi.org/10.1038/nrd2755
   PubMed Web of Science ®Google Scholar
• Zhou Y, Liang X, Chang H, Shu F, Wu Y, Zhang T, Fu Y, Zhang Q, Zhu JD, Mi M. Ampelopsin-induced autophagy protects breast cancer cells from apoptosis through Akt-mTOR pathway via endoplasmic reticulum stress. Cancer Sci 2014; 105:1279-87; PMID: 25088800
   PubMed Web of Science ®Google Scholar
• Hart LS, Cunningham JT, Datta T, Dey S, Tameire F, Lehman SL, Qiu B, Zhang H, Cerniglia G, Bi M, et al. ER stress-mediated autophagy promotes Myc-dependent transformation and tumor growth. J Clin Invest 2012; 122:4621-34; PMID: 23143306; http://dx.doi.org/10.1172/JCI62973
   PubMed Web of Science ®Google Scholar
• Lu JJ, Chen SM, Zhang XW, Ding J, Meng LH. The anti-cancer activity of dihydroartemisinin is associated with induction of iron-dependent endoplasmic reticulum stress in colorectal carcinoma HCT116 cells. Invest New Drugs 2011; 29:1276-83; PMID: 20607588; http://dx.doi.org/10.1007/s10637-010-9481-8
   PubMed Web of Science ®Google Scholar
• Gao X, Luo Z, Xiang T, Wang K, Li J, Wang P. Dihydroartemisinin induces endoplasmic reticulum stress-mediated apoptosis in HepG2 human hepatoma cells. Tumori 2011; 97:771-80; PMID: 22322845
   PubMed Web of Science ®Google Scholar
• Zhou HJ, Wang Z, Li A. Dihydroartemisinin induces apoptosis in human leukemia cells HL60 via downregulation of transferrin receptor expression. Anticancer Drugs 2008; 19:247-55; PMID: 18510170; http://dx.doi.org/10.1097/CAD.0b013e3282f3f152
   PubMed Web of Science ®Google Scholar
• Hu W, Chen SS, Zhang JL, Lou XE, Zhou HJ. Dihydroartemisinin induces autophagy by suppressing NF-kappaB activation. Cancer Lett 2014; 343:239-48; PMID: 24099910; http://dx.doi.org/10.1016/j.canlet.2013.09.035
   PubMed Web of Science ®Google Scholar
• Kimura T, Takabatake Y, Takahashi A, Isaka Y. Chloroquine in cancer therapy: a double-edged sword of autophagy. Cancer Res 2013; 73:3-7; PMID: 23288916; http://dx.doi.org/10.1158/0008-5472.CAN-12-2464
   PubMed Web of Science ®Google Scholar
• Green DR. Apoptotic pathways: the roads to ruin. Cell 1998; 94:695-8; PMID: 9753316; http://dx.doi.org/10.1016/S0092-8674(00)81728-6
   PubMed Web of Science ®Google Scholar
• Mizushima N, Yoshimori T. How to interpret LC3 immunoblotting. Autophagy 2007; 3:542-5; PMID: 17611390; http://dx.doi.org/10.4161/auto.4600
   PubMed Web of Science ®Google Scholar
• White E, DiPaola RS. The double-edged sword of autophagy modulation in cancer. Clin Cancer Res 2009; 15:5308-16; PMID: 19706824; http://dx.doi.org/10.1158/1078-0432.CCR-07-5023
   PubMed Web of Science ®Google Scholar
• Mathew R, Karantza-Wadsworth V, White E. Role of autophagy in cancer. Nat Rev Cancer 2007; 7:961-7; PMID: 17972889; http://dx.doi.org/10.1038/nrc2254
   PubMed Web of Science ®Google Scholar
• Jansen FH, Adoubi I, J C KC, DE Cnodder T, Jansen N, Tschulakow A, Efferth T. First study of oral Artenimol-R in advanced cervical cancer: clinical benefit, tolerability and tumor markers. Anticancer Res 2011; 31:4417-22; PMID: 22199309
   PubMed Web of Science ®Google Scholar
• Lai HC, Singh NP, Sasaki T. Development of artemisinin compounds for cancer treatment. Invest New Drugs 2013; 31:230-46; PMID: 22935909; http://dx.doi.org/10.1007/s10637-012-9873-z
   PubMed Web of Science ®Google Scholar
• Sotelo J, Briceno E, Lopez-Gonzalez MA. Adding chloroquine to conventional treatment for glioblastoma multiforme: a randomized, double-blind, placebo-controlled trial. Ann Intern Med 2006; 144:337-43; PMID: 16520474; http://dx.doi.org/10.7326/0003-4819-144-5-200603070-00008
   PubMed Web of Science ®Google Scholar
• Sharma N, Thomas S, Golden EB, Hofman FM, Chen TC, Petasis NA, Schönthal AH, Louie SG. Inhibition of autophagy and induction of breast cancer cell death by mefloquine, an antimalarial agent. Cancer Lett 2012; 326:143-54; PMID: 22863539; http://dx.doi.org/10.1016/j.canlet.2012.07.029
   PubMed Web of Science ®Google Scholar
• Verfaillie T, Salazar M, Velasco G, Agostinis P. Linking ER stress to autophagy: potential implications for cancer therapy. Int J Cell Biol 2010; 2010:930509; PMID: 20145727; http://dx.doi.org/10.1155/2010/930509
   PubMedGoogle Scholar
• B'Chir W, Chaveroux C, Carraro V, Averous J, Maurin AC, Jousse C, Muranishi Y, Parry L, Fafournoux P, Bruhat A. Dual role for CHOP in the crosstalk between autophagy and apoptosis to determine cell fate in response to amino acid deprivation. Cell Signal 2014; 26:1385-91; PMID: 24657471; http://dx.doi.org/10.1016/j.cellsig.2014.03.009
   PubMed Web of Science ®Google Scholar
• Bernales S, Schuck S, Walter P. ER-phagy: selective autophagy of the endoplasmic reticulum. Autophagy 2007; 3:285-7; PMID: 17351330; http://dx.doi.org/10.4161/auto.3930
   PubMed Web of Science ®Google Scholar
• Li T, Su L, Zhong N, Hao X, Zhong D, Singhal S, Liu X. Salinomycin induces cell death with autophagy through activation of endoplasmic reticulum stress in human cancer cells. Autophagy 2013; 9:1057-68; PMID: 23670030; http://dx.doi.org/10.4161/auto.24632
   PubMed Web of Science ®Google Scholar