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Research Paper

Direct measurement of hypoxia in a xenograft multiple myeloma model by optical-resolution photoacoustic microscopy

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Pages 101-105 | Received 09 Nov 2016, Accepted 18 Dec 2016, Published online: 26 Jan 2017

References

  • Kyle RA, Rajkumar SV. Multiple myeloma. Blood 2008; 111:2962-72; PMID:18332230; http://dx.doi.org/10.1182/blood-2007-10-078022
  • Nair RR, Gebhard AW, Emmons MF, Hazlehurst LA. Emerging strategies for targeting cell adhesion in multiple myeloma. Adv Pharmacol 2012; 65:143-89; PMID:22959026; http://dx.doi.org/10.1016/B978-0-12-397927-8.00006-3
  • Asosingh K, De Raeve H, de Ridder M, Storme GA, Willems A, Van Riet I, Van Camp B, Vanderkerken K. Role of the hypoxic bone marrow microenvironment in 5T2MM murine myeloma tumor progression. Haematologica 2005; 90:810-7; PMID:15951294
  • Azab AK, Hu J, Quang P, Azab F, Pitsillides C, Awwad R, Thompson B, Maiso P, Sun JD, Hart CP, et al. Hypoxia promotes dissemination of multiple myeloma through acquisition of epithelial to mesenchymal transition-like features. Blood 2012; 119:5782-94; PMID:22394600; http://dx.doi.org/10.1182/blood-2011-09-380410
  • Rajkumar SV, Mesa RA, Fonseca R, Schroeder G, Plevak MF, Dispenzieri A, Lacy MQ, Lust JA, Witzig TE, Gertz MA, et al. Bone marrow angiogenesis in 400 patients with monoclonal gammopathy of undetermined significance, multiple myeloma, and primary amyloidosis. Clin Cancer Res 2002; 8:2210-6; PMID:12114422
  • Muz B, de la Puente P, Azab F, Luderer M, Azab AK. Hypoxia promotes stem cell-like phenotype in multiple myeloma cells. Blood Cancer J 2014; 4:e262; PMID:25479569; http://dx.doi.org/10.1038/bcj.2014.82
  • Martin SK, Diamond P, Gronthos S, Peet DJ, Zannettino AC. The emerging role of hypoxia, HIF-1 and HIF-2 in multiple myeloma. Leukemia 2011; 25:1533-42; PMID:21637285; http://dx.doi.org/10.1038/leu.2011.122
  • Milosevic M, Fyles A, Hedley D, Hill R. The human tumor microenvironment: invasive (needle) measurement of oxygen and interstitial fluid pressure. Semin Radiat Oncol 2004; 14:249-58; PMID:15254868; http://dx.doi.org/10.1016/j.semradonc.2004.04.006
  • Koukourakis MI, Giatromanolaki A, Polychronidis A, Simopoulos C, Gatter KC, Harris AL, Sivridis E. Endogenous markers of hypoxia/anaerobic metabolism and anemia in primary colorectal cancer. Cancer Sci 2006; 97:582-8; PMID:16827797; http://dx.doi.org/10.1111/j.1349-7006.2006.00220.x
  • Bussink J, Kaanders JH, van der Kogel AJ. Tumor hypoxia at the micro-regional level: clinical relevance and predictive value of exogenous and endogenous hypoxic cell markers. Radiother Oncol 2003; 67:3-15; PMID:12758235; http://dx.doi.org/10.1016/S0167-8140(03)00011-2
  • Wang LV, Hu S. Photoacoustic tomography: in vivo imaging from organelles to organs. Science 2012; 335:1458-62; PMID:22442475; http://dx.doi.org/10.1126/science.1216210
  • Yao J, Wang LV. Photoacoustic microscopy. Laser Photon Rev 2013; 7:5; PMID:24416085; http://dx.doi.org/10.1002/lpor.201200060
  • Yao J, Wang LV. Photoacoustic brain imaging: from microscopic to macroscopic scales. Neurophotonics 2014; 1:1; PMID:25401121; http://dx.doi.org/10.1117/1.NPh.1.1.011003
  • Wang L, Maslov K, Wang LV. Single-cell label-free photoacoustic flowoxigraphy in vivo. Proc Natl Acad Sci U S A 2013; 110:5759-64; PMID:23536296; http://dx.doi.org/10.1073/pnas.1215578110
  • Hu S, Maslov K, Wang LV. Second-generation optical-resolution photoacoustic microscopy with improved sensitivity and speed. Opt Lett 2011; 36:1134-6; PMID:21479007; http://dx.doi.org/10.1364/OL.36.001134
  • Folkman J. Tumor angiogenesis: therapeutic implications. N Engl J Med 1971; 285:1182-6; PMID:4938153; http://dx.doi.org/10.1056/NEJM197108122850711
  • Kumar S, Witzig TE, Timm M, Haug J, Wellik L, Kimlinger TK, Greipp PR, Rajkumar SV. Bone marrow angiogenic ability and expression of angiogenic cytokines in myeloma: evidence favoring loss of marrow angiogenesis inhibitory activity with disease progression. Blood 2004; 104:1159-65; PMID:15130943; http://dx.doi.org/10.1182/blood-2003-11-3811
  • Kumar S, Gertz MA, Dispenzieri A, Lacy MQ, Wellik LA, Fonseca R, Lust JA, Witzig TE, Kyle RA, Greipp PR, et al. Prognostic value of bone marrow angiogenesis in patients with multiple myeloma undergoing high-dose therapy. Bone Marrow Transplant 2004; 34:235-9; PMID:15170170; http://dx.doi.org/10.1038/sj.bmt.1704555

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