Overexpression of HN1L promotes cell malignant proliferation in non-small cell lung cancer

References

• Siegel RL, Miller KD, Jemal A. Cancer statistics, 2016. CA Cancer J. Clin. 2016;66(1):7–30.
   PubMed Web of Science ®Google Scholar
• Heist RS, Engelman JA. SnapShot: non-small cell lung cancer. Cancer Cell. 2012;21(3):448 e2. doi:10.1016/j.ccr.2012.03.007.
   PubMedGoogle Scholar
• Varisli L, Ozturk BE, Akyuz GK, Korkmaz KS. HN1 negatively influences the beta-catenin/E-cadherin interaction, and contributes to migration in prostate cells. J. Cell. Biochem. 2015;116(1):170–8. doi:10.1002/jcb.24956.
   PubMed Web of Science ®Google Scholar
• Laughlin KM, Luo D, Liu C, Shaw G, Warrington KH, Jr., Law BK, Harrison JK. Hematopoietic- and neurologic-expressed sequence 1 (Hn1) depletion in B16.F10 melanoma cells promotes a differentiated phenotype that includes increased melanogenesis and cell cycle arrest. Differentiation. 2009;78(1):35–44. doi:10.1016/j.diff.2009.04.001.
   PubMed Web of Science ®Google Scholar
• Zujovic V, Luo D, Baker HV, Lopez MC, Miller KR, Streit WJ, Harrison JK. The facial motor nucleus transcriptional program in response to peripheral nerve injury identifies Hn1 as a regeneration-associated gene. J Neurosci. Res. 2005;82(5):581–91. doi:10.1002/jnr.20676.
   PubMed Web of Science ®Google Scholar
• Goto T, Tokunaga F, Hisatomi O. Hematological- and Neurological-Expressed Sequence 1 Gene Products in Progenitor Cells during Newt Retinal Development. Stem Cells Int. 2012;2012:436042.
   PubMed Web of Science ®Google Scholar
• Laughlin KM, Luo D, Liu C, Shaw G, Warrington KH, Jr., Qiu J, Yachnis AT, Harrison JK. Hematopoietic- and neurologic-expressed sequence 1 expression in the murine GL261 and high-grade human gliomas. Pathol. Oncol. Res. 2009;15(3):437–44. doi:10.1007/s12253-008-9147-4.
   PubMed Web of Science ®Google Scholar
• Lu KH, Patterson AP, Wang L, Marquez RT, Atkinson EN, Baggerly KA, Ramoth LR, Rosen DG, Liu J, Hellstrom I, et al. Selection of potential markers for epithelial ovarian cancer with gene expression arrays and recursive descent partition analysis. Clin. Cancer Res. 2004;10(10):3291–300. doi:10.1158/1078-0432.CCR-03-0409.
   PubMed Web of Science ®Google Scholar
• Zhang ZG, Chen WX, Wu YH, Liang HF, Zhang BX. MiR-132 prohibits proliferation, invasion, migration, and metastasis in breast cancer by targeting HN1. Biochem. Biophys. Res. Commun. 2014;454(1):109–14.
   PubMed Web of Science ®Google Scholar
• Varisli L, Gonen-Korkmaz C, Syed HM, Bogurcu N, Debelec-Butuner B, Erbaykent-Tepedelen B, Korkmaz KS. Androgen regulated HN1 leads proteosomal degradation of androgen receptor (AR) and negatively influences AR mediated transactivation in prostate cells. Mol. Cell. Endocrinol. 2012;350(1):107–17. doi:10.1016/j.mce.2011.11.027.
   PubMed Web of Science ®Google Scholar
• Varisli L, Gonen-Korkmaz C, Debelec-Butuner B, Erbaykent-Tepedelen B, Muhammed HS, Bogurcu N, Saatcioglu F, Korkmaz KS. Ubiquitously expressed hematological and neurological expressed 1 downregulates Akt-mediated GSK3beta signaling, and its knockdown results in deregulated G2/M transition in prostate cells. DNA Cell Biol. 2011;30(6):419–29. doi:10.1089/dna.2010.1128.
   PubMed Web of Science ®Google Scholar
• Ko MS, Kitchen JR, Wang X, Threat TA, Wang X, Hasegawa A, Sun T, Grahovac MJ, Kargul GJ, Lim MK, et al. Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000;127(8):1737–49.
   PubMed Web of Science ®Google Scholar
• Zhou G, Wang J, Zhang Y, Zhong C, Ni J, Wang L, Guo J, Zhang K, Yu L, Zhao S. Cloning, expression and subcellular localization of HN1 and HN1L genes, as well as characterization of their orthologs, defining an evolutionarily conserved gene family. Gene. 2004;331:115–23. doi:10.1016/j.gene.2004.02.025.
   PubMed Web of Science ®Google Scholar
• Petroziello J, Yamane A, Westendorf L, Thompson M, McDonagh C, Cerveny C, Law CL, Wahl A, Carter P. Suppression subtractive hybridization and expression profiling identifies a unique set of genes overexpressed in non-small-cell lung cancer. Oncogene. 2004;23(46):7734–45. doi:10.1038/sj.onc.1207921.
   PubMed Web of Science ®Google Scholar
• Li J, Yang H, Chen L, Li Y, Zhu Y, Dai Y, Chen K, Ai J, Zeng T, Mao X, Liu L, Li X, Guan XY. Establishment and characterization of human non-small cell lung cancer cell lines. Mol. Med. Rep. 2012;5(1):114–7.
   PubMed Web of Science ®Google Scholar
• Zhu YH, Yang F, Zhang SS, Zeng TT, Xie X, Guan XY. High expression of biglycan is associated with poor prognosis in patients with esophageal squamous cell carcinoma. Int. J. Clin. Exp. Pathol. 2013;6(11):2497–505.
   PubMed Web of Science ®Google Scholar
• Gratzner HG. Monoclonal antibody to 5-bromo- and 5-iododeoxyuridine: A new reagent for detection of DNA replication. Science. 1982;218(4571):474–5. doi:10.1126/science.7123245.
   PubMed Web of Science ®Google Scholar
• Kirilov M, Clarkson J, Liu X, Roa J, Campos P, Porteous R, Schutz G, Herbison AE. Dependence of fertility on kisspeptin-Gpr54 signaling at the GnRH neuron. Nat. Commun. 2013;4:2492. doi:10.1038/ncomms3492.
   PubMed Web of Science ®Google Scholar
• Nakahata S, Ichikawa T, Maneesaay P, Saito Y, Nagai K, Tamura T, Manachai N, Yamakawa N, Hamasaki M, Kitabayashi I, et al. Loss of NDRG2 expression activates PI3K-AKT signalling via PTEN phosphorylation in ATLL and other cancers. Nat. Commun. 2016;5:3393.
   Web of Science ®Google Scholar
• Lockyer PJ, Kupzig S, Cullen PJ. CAPRI regulates Ca(2+)-dependent inactivation of the Ras-MAPK pathway. Curr Biol. 2001;11(12): p. 981–6. doi:10.1016/S0960-9822(01)00261-5.
   PubMed Web of Science ®Google Scholar
• Fan DN, Schmitt CA. Detecting Markers of Therapy-Induced Senescence in Cancer Cells. Methods Mol Biol. 2017;1534: p. 41–52. doi:10.1007/978-1-4939-6670-7_4.
   PubMedGoogle Scholar
• Cafarotti S, Lococo F, Froesh P, Zappa F, Andre D. Target Therapy in Lung Cancer. Adv. Exp. Med. Biol. 2016;893:127–36.
   PubMedGoogle Scholar
• Sculier JP, Berghmans T, Meert AP. Advances in target therapy in lung cancer. Eur Respir Rev. 2015;24(135):23–9. doi:10.1183/09059180.00011014.
   PubMed Web of Science ®Google Scholar
• Desai A, Adjei AA. FGFR Signaling as a Target for Lung Cancer Therapy. J Thorac Oncol. 2016;11(1):9–20.
   PubMed Web of Science ®Google Scholar
• Sharma SP. New therapeutic target for non-small-cell lung cancer. The Lancet Oncology. 2014;15(12):e533. doi:10.1016/S1470-2045(14)70493-0.
   PubMed Web of Science ®Google Scholar
• Smit EF, van den Heuvel MM. PD-L1 in non-small-cell lung cancer: the third target for immunotherapy. Lancet. 2016;387(10030):1795–6. doi:10.1016/S0140-6736(16)00700-5.
   PubMed Web of Science ®Google Scholar
• Li CW, Chen BS. Investigating core genetic-and-epigenetic cell cycle networks for stemness and carcinogenic mechanisms, and cancer drug design using big database mining and genome-wide next-generation sequencing data. Cell Cycle. 2016;15(19):2593–607. doi:10.1080/15384101.2016.1198862.
   PubMed Web of Science ®Google Scholar
• Dominguez D, Tsai YH, Gomez N, Jha DK, Davis I, Wang Z. 2016. A high-resolution transcriptome map of cell cycle reveals novel connections between periodic genes and cancer. Cell Res. 26(8):946–62. doi:10.1038/cr.2016.84.
   PubMed Web of Science ®Google Scholar
• Vermeulen K, Berneman ZN, Van Bockstaele DR. Cell cycle and apoptosis. Cell prolif. 2003;36(3):165–75. doi:10.1046/j.1365-2184.2003.00267.x.
   PubMed Web of Science ®Google Scholar
• Kang KA, Piao MJ, Madduma Hewage SR, Ryu YS, Oh MC, Kwon TK, Chae S, Hyun JW. Fisetin induces apoptosis and endoplasmic reticulum stress in human non-small cell lung cancer through inhibition of the MAPK signaling pathway. Tumour Biol. 2016;37(7):9615–24. doi:10.1007/s13277-016-4864-x.
   PubMedGoogle Scholar
• Zhen Y, Li D, Li W, Yao W, Wu A, Huang J, Gu H, Huang Y, Wang Y, Wu J, et al. Reduced PDCD4 Expression Promotes Cell Growth Through PI3K/Akt Signaling in Non-Small Cell Lung Cancer. Oncol Res. 2016;23(1–2):61–8.
   Web of Science ®Google Scholar